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Welcome to the Pubget Medical Subject Headings (MESH) browser. Click on a topic or subtopic below to explore related papers. In the gold box is the most recent paper about the current MESH term, and below are 20 related papers.
Amino Acids (26):
- Excitatory Amino Acids
- Aminocaproic Acids
- Aminobutyric Acids
- Amino Acids, Diamino
- Creatine
- Amino Acids, Essential
- Amino Acids, Basic
- Amino Acid Chloromethyl Ketones
- Threonine
- Aminolevulinic Acid
- Phosphoamino Acids
- Amino Acids, Cyclic
- Amino Acids, Acidic
- Alanine
- Oxamic Acid
- Homoserine
- Glycine
- Canavanine
- Amino Acids, Branched-Chain
- RNA, Transfer, Amino Acyl
- Quisqualic Acid
- Amino Acids, Neutral
- Serine
- Kynurenine
- Amino Acids, Dicarboxylic
- Amino Acids, Sulfur
Recent article
Amino Acids
Abstract
We have undertaken an extensive structural analysis of proteins containing CUG-encoded residues and solved the crystal structures of the two natural isoforms of Candida albicans seryl-tRNA synthetase. We show that codon reassignment resulted in a nonrandom genome-wide CUG redistribution tailored to...
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PMID: 21825144
PDF is available here.
PDF is available here.
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Biomacromolecules (12)6 2011
Abstract
Currently, biomedical engineering is rapidly expanding, especially in the areas of drug delivery, gene transfer, tissue engineering, and regenerative medicine. A prerequisite for further development is the design and synthesis of novel multifunctional biomaterials that are biocompati...
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PMID: 21469742
PDF is available here.
PDF is available here.
Organic Letters (13)9 2011
Abstract
An asymmetric nucleophilic addition/protonation reaction of 3-substituted oxindoles and ethyl 2-phthalimidoacrylate has been described. This strategy can give direct access to C(γ)-tetrasubstituted α-amino acid derivatives bearing 1,3-nonadjacent stereocenters with up to 98% yield,...
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PMID: 21469699
PDF is available here.
PDF is available here.
Abstract
A new method for enhancing peptide ion identification in proteomics analyses using ion mobility data is presented. Ideally, direct comparisons of experimental drift times (t(D)) with a standard mobility database could be used to rank candidate peptide sequence assignments. Such a dat...
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PMID: 21417239
PDF is available here.
PDF is available here.
Abstract
We review modern developments in genomics and systems biology that have revolutionized our understanding of the multiple means by which translation is regulated. We suggest new means to model the process of translation in a richer framework that will incorporate information about gene sequences, the...
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PMID: 21487400
PDF is available here.
PDF is available here.
Abstract
We tested (1) how plant-based foods, together with ad libitum insect prey, affect the growth of a carnivorous ant, Solenopsis invicta, and (2) which macronutrients in these resources (i.e., carbohydrates, amino acids, or both) contribute to higher colony growth. Access to honeydew increased the prod...
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PMID: 21618912
PDF is available here.
PDF is available here.
YAKUGAKU ZASSHI (131)2 2011
Abstract
We have been developing modified nucleosides having an aminoalky linker at the pyrimidine nucleobase or sugar moiety. ODNs containing 5-N-(6-aminohexyl)carbamoyl-2'-deoxyuridine (7) were thermally stabilized about 3°C per modification and were about 160 times more stable to hydrolysis by snake veno...
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PMID: 21297374
PDF is available here.
PDF is available here.
Abstract
Pyrazinamidase (PncA) activates the first-line antituberculous drug pyrazinamide into pyrazinoic acid. The crystal structure of the Mycobacterium tuberculosis PncA protein has been determined, showing significant differences in the substrate binding cavity when compared to the pyrazinamidases from Py...
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PMID: 21283666
PDF is available here.
PDF is available here.
Abstract
We now corroborate this hypothesis by transplanting the TASK-2 extracellular pH (pH(o)) sensor in the background of a pH(o)-insensitive TASK-3 channel, which leads to the restitution of pH(o)-gating. Using a concatenated channel approach, we also demonstrate that for TASK-2 to open, pH(o) sensors mu...
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PMID: 21283586
PDF is available here.
PDF is available here.
British Journal of Nutrition (105)1 2011
Abstract
We suggest that the proteome changes in Longissimus muscle contributed to greater intramuscular lipid content in CLA-supplemented pigs....
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PMID: 20807461
PDF is available here.
PDF is available here.
Organic Letters (12)24 2010
Abstract
A highly enantioselective organocatalytic intermolecular conjugate addition of oximes to β-nitroacrylates has been developed. The highly functionalized adducts obtained are valuable precursors for asymmetric synthesis, as demonstrated by the synthesis of β(2,2)-amino acids and oxaz...
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PMID: 21080696
PDF is available here.
PDF is available here.
Abstract
In this study, hexachlorocyclotriphosphazene, N(3)P(3)Cl(6) (cylotriphosphazene), was reacted with hydrophilic and hydrophobic groups to synthesize amphiphilic phosphazene derivatives (4-12). Cylotriphosphazene was reacted triethylene glycol monomethyl ether (TEGME), dipropylene glycol monomethyl et...
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PMID: 20938539
PDF is available here.
PDF is available here.
Biochemical Journal (432)3 2010
Abstract
We generated a series of propeptide mutants to determine the minimal requirement to prevent PC-PLC enzymatic activity and to identify residues regulating compartmentalization and maturation. We found that a single residue at position P1 (Ser51) of the cleavage site is sufficient to prevent enzymatic...
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PMID: 20879990
PDF is available here.
PDF is available here.
Abstract
The rhodium-catalysed conjugate addition of arylboronic acids to an enantiopure acceptor derived from (R)-S-methylcysteine proceeds under substrate control to provide a range of functionalised phenylalanine derivatives with excellent stereocontrol via a highly diastereoselective protonation.
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PMID: 20835454
PDF is available here.
PDF is available here.
Abstract
SH3 is a ubiquitous domain mediating protein-protein interactions. Recent solution NMR structural studies have shown that a proline-rich peptide is capable of binding to the human vinexin SH3 domain. Here, an orthogonal amber tRNA/tRNA synthetase pair for (15)N/(19)F-trifluoromethyl-phenylalanine ((...
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PMID: 20946873
PDF is available here.
PDF is available here.
Abstract
We describe here how conformational preferences of non-polar amino acid residues can affect amyloid formation. The most non-polar residues promote either β-strands (Val, Ile, Phe, and Cys, VIFC) or α-helices (Leu, Ala, and Met, LAM), while the most polar residues promote only α-helices. For 12 pr...
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PMID: 20971069
PDF is available here.
PDF is available here.
Chemical Communications (46)42 2010
Abstract
An efficient method for highly diastereoselective synthesis of quaternary α-trifluoromethyl α-amino acids was developed via indium mediated allylation of (R)-phenylglycinol methyl ether based imines of trifluoropyruvate in good yields with high diastereoselectivities at room temperature; to illust...
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PMID: 20856962
PDF is available here.
PDF is available here.
Abstract
A facile synthetic route for the preparation of N-protected γ-amino β-keto esters from amino aldehydes and ethyl diazoacetate is described. The two component coupling is facilitated by tin(II) chloride followed by semipinacol rearrangement leading to the product in quantitative yield. The reaction...
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PMID: 20734011
PDF is available here.
PDF is available here.
Abstract
S-Nitrosocaptopril, a biologically active S-nitrosothiol, is generated as protonated species and isolated in the gas phase by electrospray ionization coupled to Fourier Transform Ion Cyclotron Resonance (FT-ICR) or ion-trap mass spectrometry. The structural and IR spectroscopic characterization of p...
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PMID: 20852770
PDF is available here.
PDF is available here.
Abstract
We found for the first time that JAK2/STAT3 was activated in HeLa cells when they were starved or treated with rapamycin. STAT3 activation was associated with autophagic processes, because it was completely inhibited by 3-methyladenine, partially inhibited by knockdown of molecules associated with a...
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PMID: 20930550
PDF is available here.
PDF is available here.
Abstract
We demonstrated that the insulin (INS) and amino acid (AA)-induced activation of mTORC1 is developmentally regulated in skeletal muscle (Suryawan A et al. Am J Physiol Endocrinol Metab 293: E1597-E1605, 2007). The present study aimed to characterize in more detail the effects of the postprandial ris...
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PMID: 20724570
PDF is available here.
PDF is available here.
Abstract
We provide NMR and crystallographic evidence that the PucG protein from Bacillus subtilis catalyzes the transamination between an unstable intermediate ((S)-ureidoglycine) and the end product of purine catabolism (glyoxylate) to yield oxalurate and glycine. This activity enables soil and gut bacteri...
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PMID: 20852637
PDF is available here.
PDF is available here.
British Journal of Nutrition (104)10 2010
Abstract
The aim of the present study was to investigate the cataract preventive effect of dietary histidine regimes in adult Atlantic salmon (Salmo salar L.) in seawater, both through manipulating the dietary histidine level and feeding period. Mean body weight of individually tagged Atlantic salmon at the...
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PMID: 20691125
PDF is available here.
PDF is available here.
British Journal of Nutrition (104)10 2010
Abstract
During exercise, ammonia levels are related to the appearance of both central and peripheral fatigue. Therefore, controlling the increase in ammonia levels is an important strategy in ameliorating the metabolic response to exercise and in improving athletic performance. Free amino acids can be used...
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PMID: 20594391
PDF is available here.
PDF is available here.
YAKUGAKU ZASSHI (130)11 2010
Abstract
We have previously found a new member of L-amino acid ligase, RizA, from B. subtilis NBRC3134, a microorganism that produces the peptide-antibiotic rhizocticin. We newly found that a gene at approximately 9 kbp upstream of rizA encoded a novel L-amino acid ligase RizB. Recombinant RizB synthesized h...
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PMID: 21048404
PDF is available here.
PDF is available here.
Abstract
We have summarized recent findings related to gastroduodenal mucosal defense as well as factors contributing to defensive failure, highlighting findings that illuminate new pathophysiological mechanisms.
Gastroduodenal bicarbonate secretion is mediated by prostaglandin E receptors and stimulated by...
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PMID: 20948371
PDF is available here.
PDF is available here.
Health Physics (99)5 2010
Abstract
The biokinetics of radiocarbon (¹⁴C) in rats continuously ingested in the forms of amino acids (glycine and leucine) or as foods (wheat and rapeseed) were examined and compared with each other. The differences in the biokinetics between ¹⁴C-amino acids and ¹⁴C-foods were observed in the exc...
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PMID: 20938237
PDF is available here.
PDF is available here.
Arerugi = [Allergy] (59)11 2010
Abstract
Abstract
We have revealed, for the first time, that the slight difference between the local structures of amino acid residues at the middle sites, SER45 and THR35 for streptavidin and avidin, respectively, strongly affects the microscopic reaction processes, i.e., the variation governs the type of bond as we...
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PMID: 20725689
PDF is available here.
PDF is available here.
Circulation Journal (74)11 2010
Abstract
Although lifestyle modification is the key treatment of metabolic syndrome (MetS), clinical data on the dynamical relationship between metabolic state and MetS has been limited. This study investigated the mutual correlations between demographic and biochemical variables, and the metabolic state bas...
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PMID: 20834187
PDF is available here.
PDF is available here.
Abstract
Geometric (HOMA) and magnetic (NICS) indices of aromaticity were estimated for aromatic rings of amino acids and nucleobases. Cartesian coordinates were taken directly either from PDB files deposited in public databases at the finest resolution available (≤ 1.5 Å), or from structures resulting fr...
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PMID: 20668897
PDF is available here.
PDF is available here.
Abstract
The interaction between photosensitizer anticancer drug hematoporphyrin monomethyl ether (HMME) and ctDNA has been studied based on the decreased resonance light scattering (RLS) phenomenon. The RLS, UV-vis and fluorescence spectra characteristics of the HMME-ctDNA system were investigated. Besides,...
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PMID: 20643575
PDF is available here.
PDF is available here.
Abstract
A novel beta-cyclodextrin (beta-CD) sensitized fluorescence quenching method for the determination of l-tyrosine (l-Tyr) with Mo(VI)-phenyl-fluorone (PF) as a fluorescence probe has been developed. The fluorescence intensity of Mo(VI)-PF-beta-CD was diminished as the l-tyrosine was added, the fluore...
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PMID: 20667765
PDF is available here.
PDF is available here.
Abstract
To optimize the extraction conditions of the total amino acid from Bubali Cornu.
An orthogonal test of L9 (3(4)) was designed to select optimum exaction conditions of the total amino acid. The influence of solvent concentration, the dosage of solvent and time of extraction were investigated with the...
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PMID: 21246820
PDF is available here.
PDF is available here.
Abstract
Some nutritional components of the edible seaweeds Cryptonemia obovata and Rhodymenia corallina were determined. The amino acid content ranged from 1.0 +/- 0.3 to 4174.2 +/- 14.2 mg 100 g(-1) dry wt in C. obovata and between 0.9 +/- 0.3 and 2657.0 +/- 13.5 mg 100 g(-1) dry wt in R. corallina. The mo...
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PMID: 21121265
PDF is available here.
PDF is available here.
Abstract
We used integrated proteomic and cytological approaches to probe the interconnections in rice (Oryza sativa) endosperm at the storage phase from 12 to 18 days after flowering (DAF). Starch granule packaging was completed first in the inner part of endosperm at 15 DAF and spread to almost the entire...
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PMID: 20712379
PDF is available here.
PDF is available here.
Abstract
We took an unbiased approach to studying IAV-nucleolar interactions by using stable isotope labeling with amino acids in cell culture (SILAC) in conjunction with LC-MS/MS to quantify changes in the nucleolar proteome following infection with A/PR/8/34 (H1N1) and A/Udorn/72 (H3N2) strains of the viru...
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PMID: 20701360
PDF is available here.
PDF is available here.
Abstract
A Gram-stain-positive, aerobic bacterium, designated strain BZ41(T), was isolated from hydrocarbon-contaminated soil. Phylogenetic analysis based on 16S rRNA gene sequences showed that strain BZ41(T) was related to members of the genus Agromyces and showed highest similarity with the type strain of...
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PMID: 19933590
PDF is available here.
PDF is available here.
Abstract
These results suggested that LDA cattle were in negative energy balance, but AA metabolism and protein synthesis were within a normal range. Lower glucogenic AA was due to the higher gluconeogenesis, and higher ketogenic AA was due to higher ketogenesis....
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PMID: 20460840
PDF is available here.
PDF is available here.
Journal of Physical Chemistry A: Molecules, Spectroscopy, Kinetics, Environment and General Theory (114)37 2010
Abstract
The proline cation based amino acid ionic liquid [Pro]+[NO3]− was systematically studied by density functional theory at the B3LYP/6-311++G** level. The stable geometries of the cation, anion, ion pair, as well as the ion-pair dimer [Pro]2+[NO3]2− with no imaginary frequencies were obtained and...
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PMID: 20735121
PDF is available here.
PDF is available here.
Abstract
Metabolite profiling of Cheonggukjang inoculated with different Bacillus strains including Bacillus amyloliqueciens CH86-1, Bacillus licheniformis 58, and Bacillus licheniformis 67 during fermentation, was performed using gas chromatography-time of flight-mass spectrometry after derivatization, comb...
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PMID: 20834151
PDF is available here.
PDF is available here.
Journal of Chromatography A (1217)47 2010
Abstract
This paper reports a new, simple, rapid and economical method for routine determination of 24 amino acids and biogenic amines in grapes and wine. No sample clean-up is required and total run time including column re-equilibration is less than 40min. Following automated in-loop automated pre-column d...
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PMID: 20950817
PDF is available here.
PDF is available here.
Nanotechnology (21)36 2010
Abstract
We present an experimental demonstration of a synthetic nanoporous membrane suitable for charge-selective transport of ionic species. The surfaces and walls of synthetic nanochannels, fabricated in heavy ion-tracked polyethylene terephthalate membranes are negatively charged due to the presence of c...
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PMID: 20699482
PDF is available here.
PDF is available here.
Kidney International (78)10 2010
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Kidney International (78)10 2010
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Kidney International (78)10 2010
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Kidney International (78)10 2010
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Kidney International (78)10 2010
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Kidney International (78)10 2010
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Kidney International (78)10 2010
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Kidney International (78)10 2010
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Kidney International (76) 2010
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Kidney International (76) 2010
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Kidney International (78)10 2010
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Kidney International (76) 2010
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Kidney International (76) 2010
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Kidney International (78)10 2010
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Kidney International (78)10 2010
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