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Parturient Paresis (0):
Recent article
Parturient Paresis
Abstract
Feeding anionic salts did not change the ruminal pH, total concentration of SCFA, or distribution pattern of the main SCFA acetic acid, propionic acid, butyric acid or valeric acid (p>0.05). CONCLUSIONS AND CLINICAL RELEVANCE: Feeding anionic salts has no negative side effect on the ruminal pH and c...
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PMID: 19649017
PDF is available here.
PDF is available here.
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Abstract
High serum concentrations of cholesterol and FAs were associated with an increased odds of RP. There was a 5% relative increase in the odds of RP for each 0.1 mmol/L increase in cholesterol or FAs concentration in the week before parturition. Season of parturition and twinning were also identified a...
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PMID: 19284347
PDF is available here.
PDF is available here.
Veterinary Record (163)19 2008
Abstract
Milk fever has been recognised in cattle for about 215 years and its clinical signs have not changed since they were described by Victorian veterinary surgeons in the mid-nineteenth century. It was only 80 years ago that abnormal parathyroid gland function was associated with the pathogenesis of the...
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PMID: 18997185
PDF is available here.
PDF is available here.
Abstract
The goal of this study was to investigate the efficacy of calcium chloride, sodium phosphate or a combination of these two substances administered orally immediately postpartum for the prevention of parturient paresis in cows. Thirty-two cows that had had parturient paresis at the previous calving,...
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PMID: 18714936
PDF is available here.
PDF is available here.
Veterinary Journal (176)1 2008
Abstract
The periparturient cow undergoes a transition from non-lactating to lactating at calving. The animal is tremendously challenged to maintain calcium homeostasis. Those that fail can develop milk fever, a clinical disorder that is life threatening to the cow and predisposes the animal...
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PMID: 18342555
PDF is available here.
PDF is available here.
Veterinary Journal (176)1 2008
Abstract
The periparturient or transition period of 4 weeks before and 4 weeks after calving is characterised by a greatly increased risk of disease. Hypocalcaemia around calving is a risk factor for many of these diseases and is an indirect risk factor for increased culling. The incidence of...
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PMID: 18329301
PDF is available here.
PDF is available here.
Abstract
The article describes the dynamics of changes in blood concentrations of the active substances present in the solution after its infusion to healthy cows in comparison to NaCI solution as well as the response of paretic cows to treatment with the new complex solution. Cows received a dose of 400 ml...
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PMID: 18540203
PDF is available here.
PDF is available here.
Abstract
The role of dietary calcium concentration during the feeding of anionic salts (AS) was reviewed. Hypocalcaemia is still the major cause of parturient paresis in dairy cows. Feeding AS is an established method for preventing severe hypocalcaemia by activating the calcium metabolism in the last two to...
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PMID: 18712261
PDF is available here.
PDF is available here.
Veterinary Record (161)14 2007
Abstract
Preventive strategies and risk factors for milk fever in Danish dairy herds: a questionnaire survey.
Abstract
Milk fever is a commonly recognized production disease in dairy cows around parturition. The aim of this questionnaire survey was therefore to investigate milk fever preventive strategies used in Danish dairy herds during 1998, to explore the reasons for choosing a specific strategy, and finally to...
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PMID: 17507107
PDF is available here.
PDF is available here.
Abstract
Our findings do not support the hypothesis that oral treatment with 350 g of sodium phosphate together with intravenous infusion of calcium in cows with parturient paresis results in an improved outcome, even though all the cows had hypophosphataemia as well as hypocalcaemia....
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PMID: 17645035
PDF is available here.
PDF is available here.
Abstract
The purpose of this prospective cohort study was to identify factors that place a dairy cow with uncomplicated milk fever (MF) at significant risk of becoming an alert downer cow (ADC) and to verify if these factors could be used to predict treatment outcome. Recumbent MF cows were examined before t...
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PMID: 17542366
PDF is available here.
PDF is available here.
Abstract
In our previous study, it was demonstrated that the administration of anion salts, which slightly lower the dietary cation-anion difference (DCAD), in the prepartum period is safe and effective for preventing milk fever in multiparous cows. In the present study, several clinico-pathological constitu...
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PMID: 17596033
PDF is available here.
PDF is available here.
Abstract
I concentrations in serum were almost the same among the three groups of multiparous cows with or without the oral administration of anion salts, while the levels of these serum biomarkers in the group of primiparous cows (heifer group) were much higher compared with those in the three multiparous g...
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PMID: 17409642
PDF is available here.
PDF is available here.
Abstract
We examined whether mildly altering dietary cation-anion difference (DCAD) contributes to the prevention of milk fever in dairy cows. Thirty multiparous cows and ten primiparous cows (heifer group) were used in this study and the multiparous cows were randomly divided into three groups of ten animal...
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PMID: 17339764
PDF is available here.
PDF is available here.
Animal Reproduction Science (96)3-4 2006
Abstract
This paper presents a practical, on-farm approach for the monitoring and prevention of production disease in dairy cattle. This integrated approach, should be used in an interdisciplinary way by farmers, veterinarians, nutrition advisors and other relevant professionals for the improvement of animal...
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PMID: 16979858
PDF is available here.
PDF is available here.
Journal of Dairy Science (89)7 2006
Abstract
We have hypothesized that the increased demand for calcium in periparturient cows may adversely affect intracellular calcium stores of immune cells. This reduction in intracellular calcium stores in immune cells could blunt intracellular calcium release following an activating stimulus, contributing...
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PMID: 16772578
PDF is available here.
PDF is available here.
Journal of Dairy Science (89)7 2006
Abstract
The objective of the present study was to quantify the climatic, animal, and management factors influencing incidence of milk fever (MF) in cows exposed to grazing systems. Data were extracted on 4,469 calvings of multiparous cows in a seasonal calving research herd between 1970 and 2000. Climatic d...
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PMID: 16772597
PDF is available here.
PDF is available here.
Veterinary Record (158)22 2006
Abstract
Journal of Dairy Science (89)4 2006
Abstract
The Journal of Dairy Science has increasingly become a primary outlet for scientific research concerning the health of the dairy cow and her calf. This paper attempts to highlight Journal of Dairy Science articles that have linked nutrition and nutritional strategies to reduce disease incidence on t...
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PMID: 16537961
PDF is available here.
PDF is available here.
Abstract
Our results indicate that increasing the dose of calcium administered does not improve the recovery rate of cows with parturient paresis....
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PMID: 16562723
PDF is available here.
PDF is available here.
Journal of Dairy Science (89)2 2006
Abstract
Data from 137 published trials involving 2,545 calvings were analyzed using random effects normal logistic regression models to identify risk factors for clinical hypocalcemia in dairy cows. The aim of the study was to examine which form, if any, of the dietary cation anion difference (DCAD) equatio...
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PMID: 16428636
PDF is available here.
PDF is available here.
Journal of Dairy Science (89)2 2006
Abstract
A meta-analysis of previous studies was performed to clarify the response of prepartum dairy cows to lowering dietary cation-anion difference (DCAD) and to compare different equations that have been proposed to calculate DCAD. Twenty-two published studies containing 75 treatment groups met criteria...
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PMID: 16428622
PDF is available here.
PDF is available here.
Abstract
In this study, the influence of simultaneous application of anionic salts (AS) and rumen buffer (RB) on the metabolism of dairy cows was examined. Eleven rumen fistulated, non-pregnant and non-lactating dairy cows received equal amounts of one AS (CaCl2 or CaSO4) and one RB (NaHCO3 or KHCO3) via rum...
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PMID: 16729472
PDF is available here.
PDF is available here.
Abstract
OBJECTIVE: To determine whether dietary supplementation with clinoptilolite affects the incidence of parturient paresis and serum concentrations of total calcium (tCa), inorganic phosphorus (PO(4) (2)), magnesium (Mg2+), potassium (K+), and sodium (Na+) in dairy cattle. ANIMALS: 52 dairy cows. Proce...
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PMID: 16379650
PDF is available here.
PDF is available here.
Journal of Dairy Science (88)9 2005
Abstract
The objectives were to infer heritability and genetic correlations between clinical mastitis (CM), milk fever (MF), ketosis (KET), and retained placenta (RP) within and between the first 3 lactations and to estimate genetic change over time for these traits. Records of 372,227 daughters of 2411 Norw...
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PMID: 16107417
PDF is available here.
PDF is available here.
Abstract
To determine the effect of exogenous 1,25-dihydroxyvitamin D3 [1,25(OH)2D3] combined with induced parturition on calcium (Ca) metabolism, cows received a single intramuscular injection of 1,25(OH)2D3 and prostaglandin F(2alpha) (PGF(2alpha)) closely before calving. Ten late-pregnant, multiparous Hol...
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PMID: 15933439
PDF is available here.
PDF is available here.
Journal of Dairy Science (88)5 2005
Abstract
The objectives of this study were to measure the changes in protein expression of the mammary Ca2+-ATPases during the periparturient period and to determine whether Ca2+-ATPase protein expression in the mammary gland is related to milk fever (MF) development. Abundance of Ca2+-ATPase in mammary tiss...
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PMID: 15829666
PDF is available here.
PDF is available here.
Journal of Dairy Science (88)3 2005
Abstract
We do not recommend the same approach for noninfectious disorders....
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PMID: 15738253
PDF is available here.
PDF is available here.
Abstract
Metabolic diseases of cows represent the leading internal pathology in Lithuania in terms of incidence and economic impact. This paper summarizes the mineral metabolic state of milk cows, and details the influence of feeding on serum levels of calcium, nonorganic phosphorus, magnesium, potassium, so...
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PMID: 15730133
PDF is available here.
PDF is available here.
Abstract
There is a large amount of excitement and uncertainty about the management and nutrition of the transition cow. A good rule of thumb is that the more ways that are proposed to do something, the less certain it is which are correct. The wide range of opinions currently held on this subject probably m...
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PMID: 15471627
PDF is available here.
PDF is available here.
Veterinary Record (155)2 2004
Abstract
Veterinary Record (154)21 2004
Abstract
Veterinary Journal (167)3 2004
Abstract
Veterinary Journal (167)3 2004
Abstract
The objective of this study was to evaluate the correlation between serum calcium (Ca) and inorganic phosphorus (IP) values and urine pH of cows fed common rations without the addition of anionic salts in late pregnancy. One hundred and seven Holstein cows, having completed two or more lactations an...
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PMID: 15080877
PDF is available here.
PDF is available here.
Journal of Dairy Science (87)5 2004
Abstract
High cation diets can cause milk fever in dairy cows as they induce a metabolic alkalosis reducing the ability of the cow to maintain calcium homeostasis at the onset of lactation. Adding anions to the diet can offset the effect of the high cation forages by inducing a mild metabolic acidosis, resto...
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PMID: 15290973
PDF is available here.
PDF is available here.
Veterinary Record (154)11 2004
Abstract
Journal of Dairy Science (87)2 2004
Abstract
The objective was to determine whether daily walking activity and milk yields could be used as predictors of metabolic and digestive disorders early in lactation. Data were collected from 1996 through 1999 from 1445 dairy cows in 3 Florida herds. Walking activity, milk yield, and other measures were...
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PMID: 14762096
PDF is available here.
PDF is available here.
Theriogenology (60)5 2003
Abstract
The objective of this study was to determine the effect of a calcium-energy supplement at calving on the incidence of calving-related disorders (CRD), fertility, BCS and milk yield in cows fed anionic diets and to establish any associations among outcome variables. In Florida, from October to Decemb...
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PMID: 12935862
PDF is available here.
PDF is available here.
Abstract
These results suggest that the hypocalcemic condition of parturient paretic cows in vivo causes decreased phagocytosis and resting [Ca(2+)](i) in PMNs, which may partly contribute to greater susceptibility to infection....
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PMID: 12801460
PDF is available here.
PDF is available here.
Journal of Dairy Science (86)7 2003
Abstract
These results reconfirm the occurrence of a generalized reduction in blood mononuclear leukocyte function during the periparturient period. They also suggest that the reduction in leukocyte function during the period may be, in part, due to the physiologic demands imposed on the dairy cow by the lac...
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PMID: 12906053
PDF is available here.
PDF is available here.
Preventive Veterinary Medicine (58)3-4 2003
Abstract
We present the base model and sensitivity analyses. The representation of the within-herd dynamics was based on the existing SimHerd II model. Because of the relationships between MF and other diseases, the new model (called "SimHerd III") includes diseases common in a dairy herd. The cow level risk...
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PMID: 12706054
PDF is available here.
PDF is available here.
Abstract
To determine the effects of ozone on the phagocytosis of bovine polymorphonuclear leukocytes (PMNs), ozone gas was administered in vitro on the blood and milk of healthy lactating cows, cows with acute mastitis, and cows with milk fever. In the blood of healthy dairy cattle, although there was no si...
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PMID: 12736440
PDF is available here.
PDF is available here.
Abstract
The present in vitro experiment was conducted to study the effect of two concentrations of short chain fatty acids [SCFA: 0 (control), 40 and 100 mmol/l in the buffer solution on mucosal side] on calcium ion (Ca2+) transport across the isolated rumen epithelium of two groups of sheep. One group was...
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PMID: 14511145
PDF is available here.
PDF is available here.
Abstract
Eight periparturient Holstein Friesian cows were examined for plasma tartrate-resistant acid phosphatase (TRAP) activity to assess the degree of bone metabolic activity and to evaluate the association between the change in calcium (Ca) concentration and bone metabolism during the periparturient peri...
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PMID: 12655132
PDF is available here.
PDF is available here.
Abstract
Abstract
Hypocalcaemia or milk fever is a condition resulting from an insufficiency of plasma calcium to maintain proper body function and is probably the most prevalent mineral-related disorder faced by the transition cow. It is also referred to as parturient paresis or parturient paralysis due to the recum...
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PMID: 14621397
PDF is available here.
PDF is available here.
Abstract
The background to the development of a novel concept for the prepartal activation of calcium absorption capacity as a means of preventing parturient hypocalcaemia and milk fever in grazing ruminants is described. It was hypothesised that this objective could be achieved by decreasing the bio-availab...
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PMID: 14621398
PDF is available here.
PDF is available here.
Abstract
The objective of the present study was to investigate the milk fever preventive strategies used by a representative group of Danish Milk Producers (MP). A telephone interview was performed in 1999. A total of 230 MPs were called and asked about how they prevented milk fever in the previous year. Thr...
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PMID: 14621403
PDF is available here.
PDF is available here.
Abstract
A large emphasis on precalving magnesium supplementation has substantially reduced the incidence of clinical hypocalaemia in pasture-based systems. Survey data in the major pasture-based systems suggest a 2 to 4% incidence of parturient paresis, although this can vary considerably between farms. Det...
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PMID: 14621404
PDF is available here.
PDF is available here.
Abstract
Strategies for the prevention of milk fever in the United States have made several 180 degree changes over the last several decades. During the 1950's and 1960's evidence suggested that low calcium diets could be utilized to stimulate the parathyroid prior to calving to initiate calcium homeostasis...
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PMID: 14621405
PDF is available here.
PDF is available here.
Role of vitamin D in calcium homeostasis and its use in prevention of bovine periparturient paresis.
Abstract
Calcium (Ca) is essential for life in higher animals. It is involved in the normal functioning of a wide variety of tissues and physiologic processes which include bone formation, muscle contraction, nerve transmission, blood clotting and as a second messenger regulating the actions of many hormones...
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PMID: 14621394
PDF is available here.
PDF is available here.
Abstract
The hypocalcemia associated with the clinical disease known as milk fever is due to a failure of the calcium homeostatic mechanisms in the cow to restore normal blood calcium concentration in a timely manner at the onset of lactation. The defect in calcium homeostasis appears to reside in the sensit...
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PMID: 14621395
PDF is available here.
PDF is available here.
Abstract
This paper summarise the development of the new principle of preventing parturient hypocalcaemia by reducing the bioavailability of ration calcium with calcium binders, based on the idea that a negative calcium balance would stimulate natural defence mechanisms against threatening hypocalcaemia. Syn...
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PMID: 14621399
PDF is available here.
PDF is available here.
Abstract
This article summarizes the results obtained in 6 separate studies concerned with the effect of zeolite A supplementation in the dry period on blood calcium, magnesium and phosphorus status around calving. The experiments were conducted on 5 different farms, and comprised a total of 117 cows. Two of...
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PMID: 14621400
PDF is available here.
PDF is available here.
Abstract
Abstract
These results are quite different from those in rodents and human, suggesting the different regulatory mechanism of circulating leptin concentration in cows....
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PMID: 12499694
PDF is available here.
PDF is available here.
Abstract
We carried out an expert opinion study. Animal husbandry advisors and veterinary practitioners were used as experts. The experts quantified the effect on milk fever and time needed by the farmer for two preselected options: Ca-gel fed orally peripartum and a low dietary cation-anion-difference in th...
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PMID: 12324208
PDF is available here.
PDF is available here.
Abstract
The correlation between the serum hydroxyproline concentration and serum activity levels of TRAP and BALP was examined in 41 cows. The correlated coefficient (r) was 0.6391 for TRAP and 0.3147 for BALP, respectively. Judging from the significant correlation to the serum hydroxyproline concentration,...
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PMID: 12185326
PDF is available here.
PDF is available here.
Journal of Dairy Science (85)7 2002
Abstract
One potential way of preventing parturient hypocalcemia in the dairy cow is to feed dry cow rations very low in calcium (<20 g/d); but, because it is difficult to formulate rations sufficiently low in calcium, this principle has been almost abandoned. Recent studies have shown, however, that it is p...
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PMID: 12201536
PDF is available here.
PDF is available here.