Abstract
We found that MNV infection can accelerate bacteria-induced inflammatory bowel disease (IBD) progression in Mdr1a(-/-) mice. The studies presented here examined whether MNV infection also affects the phenotype of a bacterially driven mouse model of inflammation-associated colon cancer in genetically...
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PMID: 21819691
PDF is available here.
Abstract
We carried out a frequency analysis of co-infection patterns, and a Markov chain analysis of panels of successive mixed infection time series for testing some particular gene-based grouping of the Bartonella variants with a panel of observed disease data from a rodent population. Our analysis sugges...
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PMID: 21352787
PDF is available here.
Abstract
We studied the effect of density of larvae on pre-imaginal development in 2 flea species (Xenopsylla conformis and Xenopsylla ramesis) parasitic on 2 desert rodent species (Dipodillus dasyurus, adult body mass 20 g and Meriones crassus, 80 g). We predicted a decrease in duration of development with...
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PMID: 20619065
PDF is available here.
Miklós Gyuranecz,
Béla Dénes,
Adám Dán,
Krisztina Rigó,
Gábor Földvári,
Levente Szeredi,
László Fodor,
Sallós Alexandra,
Katalin Jánosi,
Károly Erdélyi,
Katalin Krisztalovics and
László Makrai
Abstract
We examined the role of the common hamster in the natural cycle of tularemia using serologic methods on 900 hamsters and real-time polymerase chain reaction (PCR) on 100 hamsters in an endemic agricultural area. We collected 374 Ixodes acuminatus ticks from the hamsters and tested them by real-time...
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PMID: 20966287
PDF is available here.
Abstract
Five southern red-backed voles (Myodes gapperi) of the first generation of a wild-caught breeding colony were presented with lesions at the maxillary incisors consistent with elodontoma. The affected animals had a history of chronic weight loss, were >16 months of age, and were siblings. Radiographs...
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PMID: 20945662
PDF is available here.
Abstract
We developed a feed-based treatment regime in which ivermectin was the active ingredient. Rodent feed was compounded with 3 different concentrations of ivermectin (12, 24, and 48 ppm) and γ-irradiated. Postcompounding analysis revealed loss of ivermectin during manufacturing, but the remaining drug...
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PMID: 20858356
PDF is available here.
Abstract
We asked what are the factors that affect the manifestation and extent of gender-biased parasitism and studied the relationship between parasite-related (mean abundance, mean species richness and total species richness of all parasites), host-related (rodent density and proportion of reproductive ma...
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PMID: 20550754
PDF is available here.
Abstract
We investigated helminth parasitism in 2 South American rodent species, Ctenomys australis and C. talarum (Octodontidae), to determine whether the unusual solitary and subterranean nature of these hosts would impact their patterns of infection. We applied generalized linear models to infection data...
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PMID: 20500917
PDF is available here.
Abstract
We characterized a human H5N1 virus isolate (KAN-1) encoding a hemagglutinin (HA) with a K-to-E substitution at amino acid position 222 that was previously described to be selected in the lung of the infected patient. In mice, the growth of the HA(222E)-encoding virus was mainly confined to the lung...
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PMID: 20519408
PDF is available here.
Abstract
Knowledge about the protozoan parasite fauna in voles (Arvicolinae) in Austria is rather limited, although some of these pathogens play an important role in human medicine and cause zoonoses (e.g., Toxoplasma gondii and Encephalitozoon cuniculi). Others are of relevance in veterinary medicine and ha...
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PMID: 20480373
PDF is available here.
Abstract
We report 37 cases, affecting 12 strains of laboratory mice, of spontaneous infections in which S. xylosus was isolated and considered to be the primary pathogen contributing to the death or need for euthanasia of the animal. Infection with S. xylosus was the major cause of death or euthanasia in 3...
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PMID: 20819397
PDF is available here.
Abstract
Our data show that woodrats are permissive to several strains of A. phagocytophilum, but strains originating from woodrats did not cause clinical disease in horses....
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PMID: 20688687
PDF is available here.
Abstract
We investigated whether prevalence of antibodies to Toxoplasma gondii in woodchucks (Marmota monax) was related to urbanization in a Midwestern landscape. We collected serum samples from adult woodchucks captured across an urban-rural gradient in Illinois, USA in May-November 2007. We used an indire...
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PMID: 20688709
PDF is available here.
Abstract
We isolated arenavirus RNA from white-toothed woodrats (Neotoma leucodon) captured in a region of Mexico in which woodrats are food for humans. Analyses of nucleotide and amino acid sequence data indicated that the woodrats were infected with a novel Tacaribe serocomplex virus, proposed name Real de...
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PMID: 20507759
PDF is available here.
Abstract
We identified a natural focus of infection suspected to be the source of hantavirus infection in forest workers. The focus was characterized geobotanically as a montane mixed forest with the predominance of beeches within the association Dentario enneaphylli-Fagetum, alliance Fagion, sub-alliance Eu...
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PMID: 20939264
PDF is available here.
Abstract
To investigate how different routes of Toxoplasma gondii transmission influence the antibody response and infection status of deer mice (Peromyscus maniculatus), 80 mice were orally infected with 1, 5, 10, or 100 T. gondii oocysts. Ten weeks postinfection, 15 T. gondii -seropositive female mice were...
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PMID: 20557196
PDF is available here.
Abstract
Helminths, 3 cestode and 8 nematode species, including 2 new genera, 5 new species, and 1 putative new species, of nematode were collected from the digestive tracts of 23 Lorentzimys nouhuysi (Murinae; Hydromyini) from Papua New Guinea. Odilia wauensis n. sp. (Heligmonellidae) most closely resembles...
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PMID: 20557207
PDF is available here.
Abstract
Anoplocephalid cestodes have a worldwide distribution, but relatively few species are known from South American rodents. By examining the collections of the Harold W. Manter Laboratory of Parasitology and the United States National Parasite Collection, 6 new species of Monoecocestus Beddard, 1914, a...
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PMID: 20557205
PDF is available here.
Lin Zhan,
Wu Chun Cao,
Jia Fu Jiang,
Xiao Ai Zhang,
Yun Xi Liu,
Xiao Ming Wu,
Wen Yi Zhang,
Pan He Zhang,
Chang Ling Bian,
J Stephen Dumler,
Hong Yang,
Shu Qing Zuo,
Chen Yi Chu,
Wei Liu,
Jan H Richardus and
J Dik F Habbema
Abstract
We isolated the organism from rodents and sheep in northeastern China. We isolated 3 strains (2 from rodents and 1 from sick sheep) through propagation in BALB/c mice and then cell culture in HL60 cells. The 3 isolates were identified by Wright-Giemsa staining, immunofluorescence, and electronic mic...
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PMID: 20409364
PDF is available here.
Abstract
Parastrongylus cantonensis is a parasite of murid rodents that can infect humans and cause health problems as eosinophilic meningitis. Although it is endemic in south Asia, the Pacific islands, Australia, USA, and a few Caribbean islands, it has been extended to new geographical regions. In the Cana...
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PMID: 20153283
PDF is available here.
Abstract
Rat theilovirus is a commonly reported infection in research rat colonies. The author's institution experienced an outbreak of rat theilovirus in a breeding colony of unique outbred rats. To manage this outbreak, the institution chose to use a 'test and cull' strategy because this approach is report...
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PMID: 20410900
PDF is available here.
S R Boutin,
Z Shen,
P L Roesch,
S M Stiefel,
A E Sanderson,
H M Multari,
E A Pridhoko,
J C Smith,
N S Taylor,
J J Lohmiller,
F E Dewhirst,
H J Klein and
J G Fox
Abstract
Helicobacter pullorum is a bacterial pathogen in humans. By using microaerobic culture techniques, H. pullorum was isolated from the feces of barrier-maintained mice and identified, on the basis of biochemical, restriction fragment length polymorphism, and 16S rRNA gene sequence analyses. This findi...
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PMID: 20220161
PDF is available here.
Takaaki Koma,
Kumiko Yoshimatsu,
Noemi Pini,
David Safronetz,
Midori Taruishi,
Silvana Levis,
Rika Endo,
Kenta Shimizu,
Shumpei P Yasuda,
Hideki Ebihara,
Heinz Feldmann,
Delia Enria and
Jiro Arikawa
Abstract
These results indicated that a screening ELISA using an E. coli-expressed antigen followed by a serotyping ELISA using trN100s is useful for epidemiological surveillance in regions where two or more hantavirus species cocirculate....
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PMID: 20335425
PDF is available here.
Abstract
Histiocytic sarcoma (HS) and histiocyte-associated lymphoma (HAL) of mice are difficult to distinguish histologically. Studies of multiple cases initially diagnosed as HS or HAL allowed us to define HS as round, fusiform, or mixed cell types that were F4/80+, Mac-2+, and PAX5-; that lacked markers f...
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PMID: 20472805
PDF is available here.
Abstract
In this retrospective study, spontaneous osteosarcomas were found in 85 of 1,202 (7.1%) nonobese diabetic (NOD) and NOD-derived mice. Gross tumors were evident at an average age of 155.8 days in male mice and 151.4 days in female mice. Compared with male mice, female mice had a statistically insigni...
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PMID: 20348488
PDF is available here.
Abstract
We asked whether the occurrence and the extent of host gender-biased parasitism vary among higher parasite taxa, among individual species within these taxa and within parasite species among localities. To answer this question, we studied prevalence, abundance, species richness and the level of aggre...
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PMID: 19835648
PDF is available here.
Abstract
Heligmosomoides craigi n. sp. (Nematoda: Heligmosomoidea) is described from Microtus limnophilus Büchner, 1889 (Rodentia: Cricetidae) from Rangtang, Sichuan, China. It is related to H. protobullosus Asakawa, 1987 and H. longispiculum Tokobaev & Erkulov, 1966 both parasites of Microtus spp. from Jap...
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PMID: 20387734
PDF is available here.
Abstract
We have shown that primary blood stage infection induced the expansion of CD4+ T cells and CD8+ T cells in adult resistant rats while the number of CD4+CD25+ cells was found to be higher in young susceptible rats. In this work, the respective contribution of each cell population was determined in yo...
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PMID: 20387739
PDF is available here.
Abstract
Ten spontaneous mammary gland tumors affecting guinea pigs (GP) were analyzed histologically and immunohistochemically. Histologically, 3 were benign (2 simple adenomas and 1 benign mixed tumor) and 7 were malignant (1 simple solid carcinoma and 6 simple tubulopapillary carcinomas)....
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PMID: 20106793
PDF is available here.
Abstract
C hepatica, an important zoonotic parasite, and C fasciolaris are common parasites in rodents. In rodent livers, C hepatica causes sequential morphologic changes that are designated as early, intermediate, or late phase, and C fasciolaris forms cysts surrounded by fibroplasia and gra...
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PMID: 20118322
PDF is available here.
Abstract
Borna disease is a severe viral-induced disorder of the central nervous system of horses, sheep, and a few other animal species, occurring in certain areas of central Europe. Pathogenesis and epidemiology of natural Borna disease virus (BDV) infections are still not fully understood;...
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PMID: 20133953
PDF is available here.
Abstract
Our findings show that, after an environmental disaster, the behaviour of helminth species might be related to their pre-catastrophe presence, their biological cycles, the host's immunological condition, the change of host dynamics, the direct effects of the perturbation, and the processes related t...
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PMID: 19580689
PDF is available here.
Abstract
We report 2 cases of Sin Nombre virus (SNV) infection in field workers, possibly contracted through rodent bites. Screening for antibodies to SNV in rodents trapped in 2 seasons showed that 9.77% were seropositive. Quantitative real-time PCR showed that 2 of 79 deer mice had detectable titers of SNV...
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PMID: 20113567
PDF is available here.
Abstract
Noroviruses belong to the Caliciviridae family. They are a major cause of sporadic cases and outbreaks of gastroenteritis in all age groups, and are responsible for a considerable disease burden in industrialized countries. Noroviruses are single-stranded RNA viruses, and show great genetic diversit...
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PMID: 20132778
PDF is available here.
Abstract
A 3-year-old, intact female guinea pig (Cavia porcellus) was presented for anorexia and abdominal distention of 24 hours' duration. Radiographs revealed a severely distended stomach, suggestive of severe gastric dilatation or gastric dilatation-volvulus (GDV). Exploratory surgery was recommended, bu...
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PMID: 20439940
PDF is available here.
Abstract
At first blush, an outbreak of mouse hepatitis virus or epizootic diarrhea of infant mice virus in a research colony of laboratory mice may not seem like a disaster. However, irrespective of magnitude, such an outbreak at an academic institution is disruptive for researchers at all levels. It can be...
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PMID: 20375435
PDF is available here.
Abstract
We surveyed P. aeruginosa distribution in chinchillas bred as pets or laboratory animals. We also characterized the isolates from these chinchillas by testing for antibiotic susceptibility and by gene analysis.
P. aeruginosa was isolated from 41.8% of the 67 chinchillas included in the study. Slide...
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PMID: 21083906
PDF is available here.
Abstract
Suppuration of the preputial gland in mice occurs as a septic complication of fight wounds around the external genitalia. Currently reported bacterial isolates from these lesions are limited to Staphylococcus aureus, Pasteurella pneumotropica, and Klebsiella oxytoca. In the context of a pilot experi...
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PMID: 20122320
PDF is available here.
Kyrre Linne Kausrud,
Mike Begon,
Tamara Ben Ari,
Hildegunn Viljugrein,
Jan Esper,
Ulf Buntgen,
Herwig Leirs,
Claudia Junge,
Bao Yang,
Meixue Yang,
Lei Xu and
Nils Chr Stenseth
Abstract
We find that high-resolution palaeoclimatic indices correlate with plague prevalence and population density in a major plague host species, the great gerbil (Rhombomys opimus), over 1949-1995. Climate-driven models trained on these data predict independent data on human plague cases in early 20th-ce...
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PMID: 20799946
PDF is available here.
Abstract
The xenotropic/polytropic subgroup of mouse leukemia viruses (MLVs) all rely on the XPR1 receptor for entry, but these viruses vary in tropism, distribution among wild and laboratory mice, pathogenicity, strategies used for transmission, and sensitivity to host restriction factors. M...
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PMID: 21118532
PDF is available here.
Abstract
Morphofunctional changes induced by the tapeworm in the thymus and blood of its definitive host, by an example of the experimental model "Diphyllobothrium dendriticum--Mesocricetus auratus", have been investigated. The morphofunctional changes in the thymus and immunological transformations in the o...
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PMID: 20536005
PDF is available here.
Abstract
We conclude that the distribution and abundance of intermediate host structure the gastrointestinal parasite community of the Arctic fox on the Svalbard archipelago....
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PMID: 19723357
PDF is available here.
Abstract
I reproduction toxicity study died at the age of fifteen weeks. At necropsy, the thymus was abnormally enlarged and virtually obliterated the thoracic cavity. Histopathological examination of thymus revealed abundant cell population consisting of mature lymphocytes and few lymphoblasts arranged in c...
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PMID: 20100842
PDF is available here.
Abstract
Histological examination of the heart of a clinically normal, 10-week-old female Han Wistar rat revealed a 600 x 400-mum mass of ectopic thyroid tissue within the subendothelial connective tissue of the aortic valve. The mass protruded into the left ventricular lumen and was composed...
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PMID: 20100844
PDF is available here.
Abstract
Spontaneous salivary gland tumors in rats are rare. The authors report a poorly differentiated carcinoma of a submandibular gland in a ten-week-old rat that was positive for vimentin. Microscopically, the neoplastic cells showed a diffuse growth pattern in most areas of the tumor mas...
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PMID: 20124499
PDF is available here.
Abstract
The aim of the study was to identify the causes underlying overgrowth of incisors in chinchillas through an analysis of selected plasma electrolyte concentrations, with particular consideration of minerals involved in the formation of osseous tissue, i.e., Ca, Mg, and P. The analysis involved 40 fem...
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PMID: 20420204
PDF is available here.
Abstract
The Kilham rat virus (KRV) is a parvovirus originally isolated from a rat sarcoma in the late 1950s. The clinical signs associated with a natural KRV infection include foetal resorption in dams, runting, ataxia, cerebellar hypoplasia and jaundice in suckling rats, and sudden death, scrotal cyanosis,...
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PMID: 20461290
PDF is available here.
Abstract
The main objective of this study was to investigate the role of wild rodents as Leptospira spp. reservoirs in a suburban area of Tandil city, Buenos Aires province (Argentina), where a person had died due to pulmonary leptospirosis. The specific objectives were: to estimate the rodent density near t...
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PMID: 20589335
PDF is available here.
Abstract
A 21-year-old male presented at the emergency room with jaundice, itching, dry cough, malaise and weight loss of 10 kg during the preceding four weeks. Eighteen months earlier, the patient had suffered an automobile accident leading to polytrauma. Serological markers for viral or other causes of hep...
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PMID: 20072994
PDF is available here.
Abstract
Human cases of Q fever appear to be common in Northern Ireland compared to the rest of the British Isles. The purpose of this study was to describe the seroepidemiology of Coxiella burnetii infection in cattle in Northern Ireland in terms of seroprevalence and determinants of infection. A total of 5...
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PMID: 19480726
PDF is available here.
Abstract
We report, for the first time, an incidental finding of Calodium hepaticum infestation in a sub-adult female Cape ground squirrel (Xerus inaurus). Post mortem examination of the squirrel revealed severe haemoperitoneum, splenomegaly and hepatomegaly with miliary white spots distributed diffusely thr...
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PMID: 20458874
PDF is available here.
Abstract
Information related to infection of wild rodents or lagomorphs in Canada by Francisella tularensis, Yersinia pestis, other Yersinia spp., and Clostridium piliforme was searched for this study. Reports on tularemia in humans linked to these species came from diagnostic databases, literature, wildlife...
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PMID: 20190973
PDF is available here.