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Welcome to the Pubget Medical Subject Headings (MESH) browser. Click on a topic or subtopic below to explore related papers. In the gold box is the most recent paper about the current MESH term, and below are 20 related papers.
Vesicular Stomatitis (0):
Recent article
Vesicular Stomatitis
Abstract
We show that mouse embryonic fibroblasts and mice lacking S6K1 and S6K2 are more susceptible to vesicular stomatitis virus (VSV) infection than their WT counterparts as a result of an impaired type I IFN response. We used this knowledge to employ a pharmacoviral approach to treat MGs. The highly spe...
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PMID: 20080710
PDF is available here.
PDF is available here.
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Abstract
We found that the transcript levels of IL-6, IL-8, IL-12, TNF-alpha and TLR3 were increased obviously whereas TGF-beta showed no significant difference. TPEC-J2 cell did not secrete IL-2, IL-10, IFN-alpha and IFN-gamma. CONCLUSION: The level of inflammatory response was increased when VSV infected T...
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PMID: 19873763
PDF is available here.
PDF is available here.
Abstract
Vesicular stomatitis New Jersey virus (VSNJV) is an insect-transmitted Rhabdovirus causing vesicular disease in domestic livestock including cattle, horses, and pigs. Natural transmission during epidemics remains poorly understood, particularly in cattle, one of the most affected species during outb...
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PMID: 19645291
PDF is available here.
PDF is available here.
Abstract
Abstract
The dynamics of viral infection spread, whether in laboratory cultures or in naturally infected hosts, reflects a coupling of biological and physical processes that remain to be fully elucidated. Biological processes include the kinetics of virus growth in infected cells while physical processes inc...
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PMID: 20027375
PDF is available here.
PDF is available here.
Abstract
A majority of adults without evidence of exposure to vesicular stomatitis virus (VSV) have serum IgG antibodies that interact with pro-inflammatory TLR7 in the presence of VSV, and enhance several aspects of VSV-induced IFN-alpha production. Enhancing IgG antibody enables human PBMC to make IFN-alph...
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PMID: 18649334
PDF is available here.
PDF is available here.
Cell Cycle (7)15 2008
Abstract
We show that PKR and HRI have no effects on VSV replication as opposed to PERK and GCN2, which exhibit strong inhibitory effects. When MEFs containing the serine 51 to alanine mutation of eIF2alpha were used, we found that VSV replication is independent of eIF2alpha phosphorylation. Nevertheless, th...
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PMID: 18677106
PDF is available here.
PDF is available here.
Journal of Immunology (181)2 2008
Abstract
We previously reported that the lack of serglycin proteoglycan affects secretory granule morphology and granzyme B (GrB) storage in in vitro generated CTLs. In this study, the role of serglycin during viral infection was studied by infecting wild-type (wt) mice and serglycin-deficient (SG(-/-)) mice...
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PMID: 18606656
PDF is available here.
PDF is available here.
Abstract
We show that the length of dsRNA is important for differential recognition by RIG-I and MDA5. The MDA5 ligand, polyinosinic-polycytidylic acid, was converted to a RIG-I ligand after shortening of the dsRNA length. In addition, viral dsRNAs differentially activated RIG-I and MDA5, depending on their...
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PMID: 18591409
PDF is available here.
PDF is available here.
Abstract
I interferons (IFNs) and proinflammatory cytokines. RLRs recognize distinct and overlapping sets of viruses, but the mechanisms that dictate this specificity were unknown. A new study now provides evidence for size-based discrimination of double-stranded RNA (dsRNA) by RLRs and suggests how host cel...
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PMID: 18591413
PDF is available here.
PDF is available here.
Abstract
We used RNA virus populations of large size and high mutation rate to study the impact of historical environment on genome evolution, thus increasing our ability to detect repeatable patterns in the evolution of genetic architecture. Experimental vesicular stomatitis virus populations were evolved o...
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PMID: 18353798
PDF is available here.
PDF is available here.
Journal of Virology (82)9 2008
Abstract
We propose a simpler method. We infer the initial population structure of vesicular stomatitis virus (VSV) by fitting a mathematical model of asexual evolution to an extensive set of measurements of VSV fitness dynamics under various conditions, including new and previously published data. The infer...
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PMID: 18287227
PDF is available here.
PDF is available here.
Journal of Virology (82)5 2008
Abstract
We transfected reporter mRNAs into cells at various times relative to the time of infection and measured their rate of translation in mock- and VSV-infected cells. We found that translation of mRNAs transfected during infection was not inhibited but that translation of mRNAs transfected prior to inf...
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PMID: 18094194
PDF is available here.
PDF is available here.
Journal of Immunology (180)4 2008
Abstract
We show that Pg inhibits TLR9-induced IFN-alpha production by human and mouse pDCs and that DMPA impairs TLR9- and virus-induced IFN-alpha production by pDCs in mice, providing a potential explanation for how DMPA impairs innate antiviral immunity in women. Pg failed to inhibit the Mda-5 pathway of...
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PMID: 18250406
PDF is available here.
PDF is available here.
Abstract
A highly sensitive and specific one-step multiplex RT-PCR assay has been developed and standardised for the simultaneous and differential detection of the most important vesicular viruses affecting livestock: foot-and-mouth disease virus (FMDV), swine vesicular disease virus (SVDV), and vesicular st...
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PMID: 17964668
PDF is available here.
PDF is available here.
Abstract
Control of insect populations in the 2 weeks before the VS investigation decreased the odds of disease for premises where vegetation coverage was grassland or pasture (odds ratio [OR], 0.08; 95% confidence interval [CI], 0.01 to 0.7). Odds of VS for premises covered with grassland or pasture increas...
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PMID: 18275393
PDF is available here.
PDF is available here.
Archives of Virology (153)7 2008
Abstract
We describe the full-length genomic sequences and organization of the prototype strains of VSIV-2 Cocal virus (COCV) and VSIV-3 Alagoas virus (VSAV). These viruses showed similar genomic organizations to VSIV field isolates except that the non-structural C'/C proteins, markedly conserved throughout...
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PMID: 18512001
PDF is available here.
PDF is available here.
Journal of Neurovirology (13)5 2007
Abstract
I interferon (IFN) is critical for resistance of mice to infection with vesicular stomatitis virus (VSV). Wild type (wt) VSV infection did not induce type I IFN production in vitro or in the central nervous system (CNS) of mice; however IFN-beta was detected in lungs, spleen, and serum within 24 h....
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PMID: 17994428
PDF is available here.
PDF is available here.
Journal of Virology (81)20 2007
Abstract
We show that mRNA cap formation is further distinct, requiring a specific cis-acting signal in the RNA. Using recombinant VSV, we determined the function of the eight conserved positions of the gene-start sequence in mRNA initiation and cap formation. Alterations to this sequence compromised mRNA in...
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PMID: 17686869
PDF is available here.
PDF is available here.
Abstract
The highly contagious transboundary animal diseases (TADs), e.g., foot-and-mouth disease (FMD), classical swine fever (CSF), African swine fever (ASF) and highly pathogenic avian influenza (HPAI) are regularly occurring and re-occurring on various continents, causing severe losses. This epidemiologi...
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PMID: 18084935
PDF is available here.
PDF is available here.
Abstract
As our understanding of the molecular aspects of human disease increases, it is becoming possible to create designer therapeutics that are exquisitely targeted and have greater efficacy and fewer side effects. One class of targeted biological agents that has benefited from recent advances in molecul...
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PMID: 15121047
PDF is available here.
PDF is available here.