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Bursa of Fabricius (0):
Recent article
Bursa of Fabricius
Abstract
Infection with pigeon circovirus (PiCV) has been associated with young pigeon disease syndrome (YPDS), which is considered to be a multifactorial disease. The factors that determine whether birds succumb to clinical disease are not known. To evaluate the potential effect of vaccination with a commer...
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PMID: 20806655
PDF is available here.
PDF is available here.
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British Poultry Science (51)1 2010
Abstract
These results give some morphological evidence for immunosuppression induced by high temperature exposure during the embryonic development. Temperature distribution and air circulation in incubator should be questioned in the case of lower broiler flock immunity....
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PMID: 20390568
PDF is available here.
PDF is available here.
Abstract
I based one-step real-time reverse transcriptase polymerase chain reaction was developed for the detection and differentiation of very virulent (vv) and classical strains of infectious bursal disease virus (IBDV). The assay showed high PCR efficiency >93% and high reproducibility with coefficient of...
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PMID: 19591873
PDF is available here.
PDF is available here.
Avian Diseases (53)3 2009
Abstract
Infectious bursal disease virus (IBDV) is an immunosuppressive virus which primarily infects IgM B-cells in the bursa of Fabricius. Flow cytometric analysis was used to phenotype B-cell populations in the bursa and spleen following IBDV infection. In the bursa, two IgM B-cell subpopulations, designa...
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PMID: 19848071
PDF is available here.
PDF is available here.
Abstract
Cryptosporidiosis has a worldwide geographical and zoological distribution. Cryptosporidium baileyi oocysts were isolated from the bursa of Fabricius (BF) of 4 weeks-old of 100 broilers. Twenty five broiler chicks of 2 day old free from cryptosporidial infection were inoculated intratracheally at a...
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PMID: 19795766
PDF is available here.
PDF is available here.
Abstract
The aim of this study was to examine the efficacy of in ovo prime-boost vaccination against infectious bursal disease virus (IBDV) using a DNA vaccine to prime in ovo followed by a killed-vaccine boost post hatching. In addition, the adjuvant effects of plasmid-encoded chicken interleukin-2 and chic...
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PMID: 19461208
PDF is available here.
PDF is available here.
Avian Diseases (53)2 2009
Abstract
This report documents the occurrence of a very virulent infectious bursal disease virus (vvIBDV) in Northern California commercial brown pullets. Diagnosis was made from multiple accessions from two neighboring and epidemiologically related ranches submitted to the California Animal Health and Food...
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PMID: 19630244
PDF is available here.
PDF is available here.
Avian Diseases (53)2 2009
Abstract
An outbreak of systemic histomoniasis in 9-to-11-wk-old meat-type male turkeys associated with high mortality is reported. Clinical signs in turkeys included anorexia, depression, diarrhea, loss of weight, and increased mortality between 7 and 13 wk of age. Seven-week cumulative mortality in the tur...
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PMID: 19630229
PDF is available here.
PDF is available here.
Immunogenetics (61)3 2009
Abstract
We pyrosequenced four small RNA libraries derived from the spleen and the bursa of Fabricius of embryonic chicks at days 15 and 20 of development. A total of 90,322 sequence reads were obtained, among which 44,387 reads represented known chicken miRNAs, 3,503 reads were not found in the Gallus gallu...
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PMID: 19198828
PDF is available here.
PDF is available here.
Avian Diseases (53)1 2009
Abstract
We speculate that the changes in splenic CD4+ and IgM+ cell populations are associated with protective immune responses against IBDV in the host....
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PMID: 19432007
PDF is available here.
PDF is available here.
Avian Diseases (53)1 2009
Abstract
The effects of chicken anemia virus (CAV) and infectious bursal disease virus (IBDV) coinfection in commercial layer-type and meat-type (broiler) chickens with specific maternal immunity were evaluated. In addition, the broiler progeny used had been vaccinated in ovo against IBDV. Layer chickens wer...
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PMID: 19432010
PDF is available here.
PDF is available here.
Molecular and Cellular Biochemistry (320)1-2 2009
Abstract
We described molecular cloning, characterization and distribution of glycosylphosphatidylinositol (GPI)-anchored Arts, Art7.1 and Art7.2 (formerly, we referred as cgArt1 and cgArt2, respectively) in chicken tissues (Terashima et al (2005) Biochem J 389:853-861). Here, we demonstrate for the first ti...
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PMID: 18696216
PDF is available here.
PDF is available here.
Abstract
The pathological and immunological effects of two infectious bursal disease (Gumboro disease) vaccines containing attenuated virus were evaluated under experimental conditions. A total of 200 conventional broiler chicks were divided into three batches, two of which were administered an experimental...
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PMID: 19284047
PDF is available here.
PDF is available here.
Avian Diseases (52)4 2008
Abstract
These results suggest that environmentally acquired L. monocytogenes can transiently colonize the liver and synovial tissues of stressed turkeys and may be a sporadic source of contamination of processing plants....
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PMID: 19166048
PDF is available here.
PDF is available here.
Avian Diseases (52)4 2008
Abstract
Immunosuppression in chickens as a consequence of Cryptosporidium baileyi infection may compromise the effectiveness of vaccination for control of avian influenza (AI) H5N1. In a 13-wk study using 260 specific-pathogen-free chicks, immunological response and bursa weight:body weight ratios following...
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PMID: 19166065
PDF is available here.
PDF is available here.
Abstract
We show that both the RAD9(-/-) and RAD17(-/-) mutants exhibit substantially reduced immunoglobulin gene conversion. However, the level of nontemplated immunoglobulin point mutation increased in these mutants, a finding that is reminiscent of the phenotype resulting from the loss of RAD51 paralogs o...
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PMID: 18662998
PDF is available here.
PDF is available here.
Abstract
The bursa of Fabricius serves as an important tissue in the process of Marek's disease virus (MDV) pathogenesis, since B cells of the bursa harbor the cytolytic phase of MDV replication cycle. In the present study, host responses associated with MDV infection in the bursa of Fabricius of chickens we...
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PMID: 18675437
PDF is available here.
PDF is available here.
Avian Diseases (52)3 2008
Abstract
Pigeon circovirus (PiCV) infection and young pigeon disease syndrome (YPDS), associated with high morbidity and mortality, have been recognized in young racing pigeons from large portions of Central Europe. There exist a number of data indicating that YPDS is a consequence of PiCV infection and subs...
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PMID: 18939623
PDF is available here.
PDF is available here.
Avian Diseases (52)3 2008
Abstract
Recently, pathogenesis studies, using genetically distinct turkey-origin reoviruses (TRVs), revealed that poults infected with certain TRV isolates had moderate to severe bursal atrophy, suggesting virus-induced immune dysfunction. In order to characterize the effect of TRV infection on the turkey i...
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PMID: 18939624
PDF is available here.
PDF is available here.
Avian Pathology (37)4 2008
Abstract
The presence of the very virulent (vv) Brazilian strain of infectious bursal disease virus (IBDV) was determined in the bursa of Fabricius, thymus and liver of 2-week-old broilers from a flock with a higher than expected mortality. For this purpose, a direct in situ reverse transcriptase (RT)-linked...
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PMID: 18622865
PDF is available here.
PDF is available here.
Abstract
Reverse transcription polymerase chain reaction (RT-PCR) of turkey astrovirus (TAstV) capsid and polymerase genes was applied to the bursa of Fabricius (BF), thymus (TH), spleen (SP) and cloacal swabs (CS) of young poults with "Poult enteritis complex" (PEC). The histological lesions included atroph...
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PMID: 18628608
PDF is available here.
PDF is available here.
Abstract
The illegal use of beta2-agonists as repartitioning agents to improve production performance and carcass composition can induce changes in various organs of exposed animals. The aim of the present study was to evaluate the effects induced by dietary beta-agonists on beta-AR, AnR and GR in male broil...
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PMID: 18407392
PDF is available here.
PDF is available here.
Avian Diseases (52)2 2008
Abstract
The development and use of recombinant vaccine vectors for the expression of poultry pathogens proteins is an active research field. The adeno-associated virus (AAV) is a replication-defective virus member of the family Parvoviridae that has been successfully used for gene delivery in humans and oth...
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PMID: 18646463
PDF is available here.
PDF is available here.
Avian Diseases (52)2 2008
Abstract
These results suggest that coarse spray vaccination can be considered as another tool to control IBDV in the field....
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PMID: 18646460
PDF is available here.
PDF is available here.
Avian Pathology (37)2 2008
Abstract
The pathogenicity of three different type 2 turkey astroviruses (TAstV-2) was studied in specific pathogen free turkeys. These viruses differ based on sequence analysis of the capsid gene. Poults were inoculated at 2 days of age and examined during 14 days for clinical signs and virus shedding. All...
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PMID: 18393099
PDF is available here.
PDF is available here.
Experimental Parasitology (118)4 2008
Abstract
In the present investigation, a polyclonal antibody-based immunohistochemical technique was developed to localize Histomonas meleagridis in formalin-fixed, paraffin-embedded tissues of experimentally infected turkeys. The developed technique was highly specific for histomonads as no immunohistochemi...
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PMID: 18155698
PDF is available here.
PDF is available here.
Abstract
Experiments were conducted with chickens exposed to corticosterone and lipopolysaccharide (LPS) from Escherichia coli, with the aim of evaluating and differentiating their effects on endocrine, metabolic and immune response. Both, corticosterone and LPS significantly elevated plasma corticosterone c...
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PMID: 18024213
PDF is available here.
PDF is available here.
Poultry Science (87)2 2008
Abstract
A panel of monoclonal antibodies was generated against the guinea fowl's bursal cells. One of the antibodies, designated BoA1, recognized both cortical and medullary B cells of bursal follicles and B cell dependent regions of peripheral lymphoid organs, like germinal centers and splenic periellipsoi...
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PMID: 18212380
PDF is available here.
PDF is available here.
Abstract
We determined that GAPF-detected palindromes are abundant and distributed nonrandomly throughout the genome of bursal lymphoma cells, frequently at preexisting short inverted repeats. By combining GAPF with chromatin immunoprecipitation (ChIP), we found a significant association between occupancy of...
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PMID: 18636108
PDF is available here.
PDF is available here.
Abstract
Abstract
We identified and characterised chicken receptors BAFFR and TACI, but found that the gene encoding the third BAFF-binding receptor, BCMA, was disrupted, implying differences in mechanisms for maintenance of long-lived antibody responses. A BAFFR-Ig fusion protein expressed in vivo lowered B cell num...
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PMID: 18395254
PDF is available here.
PDF is available here.
Abstract
We demonstrated that intramuscular administration of oligodeoxynucleotides containing CpG motifs (CpG-ODN) induces protection in neonatal chicks against a lethal challenge of Escherichia coli. However, the mechanism of induction of the protection was not clear. In an attempt to elucidate the mechani...
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PMID: 18395255
PDF is available here.
PDF is available here.
Abstract
Expression of growth hormone (GH) and GH receptor (GHR) genes in the bursa of Fabricius of chickens suggests that it is an autocrine/paracrine site of GH production and action. The cellular localization of GH and GH mRNA within the bursa was the focus of this study. GH mRNA was expressed mainly in t...
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PMID: 18539326
PDF is available here.
PDF is available here.
Abstract
We have investigated the use of embryo-safe IBDV and IBV vaccines and the effects of co-delivery of a turkey herpesvirus recombinant expressing bioactive chicken IL-2 (IL-2/HVT). Co-delivery of the IL-2/HVT with low doses of the IBDV or IBV vaccines significantly increased the antibody response agai...
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PMID: 17996994
PDF is available here.
PDF is available here.
British Poultry Science (48)6 2007
Abstract
1. An experiment on 1-week-old, White Leghorn female chicks was conducted to study the effect of aflatoxin AFB1 on weight gain, feed intake, feed gain ratio, age at sexual maturity, production and quality of eggs, retention of nutrients, pathoanatomical and histopathological parameters, and also on...
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PMID: 18085454
PDF is available here.
PDF is available here.
Abstract
Corticosterone, a glucocorticoid secreted during stress responses, has a range of actions that help birds respond to stressors. Although effects of corticosterone treatment have been described in several avian species, the impacts of defined increases in plasma corticosterone on early development an...
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PMID: 17681843
PDF is available here.
PDF is available here.
Abstract
Clinically severe disease was produced in ostriches aged 4 weeks by oral infection with a virulent strain of infectious bursal disease virus (vIBDV), namely strain Faragher 52/70. Four days after infection the birds were humanely killed and tissue samples, including thymus, bursa of Fabricius (BF),...
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PMID: 17880991
PDF is available here.
PDF is available here.
Poultry Science (86)11 2007
Abstract
Prolactin (PRL) is a pituitary hormone with multiple homeostatic roles among vertebrates. Although it has mainly been studied in relation to its role during the initiation and maintenance of incubation behavior in avian species, it has also been shown to act on the immune system. In this study, leve...
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PMID: 17954592
PDF is available here.
PDF is available here.
Journal of Immunology (179)8 2007
Abstract
We identify chicken CD83 (chCD83) as the avian equivalent of the human and murine DC marker CD83. We demonstrate for the first time that unlike human and murine CD83, chCD83 is uniquely expressed in the B cell areas of secondary lymphoid organs and in organs with no human or murine equivalent such a...
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PMID: 17911597
PDF is available here.
PDF is available here.
Avian Pathology (36)5 2007
Abstract
A real-time quantitative polymerase chain reaction was utilized to study the in vivo replication of Marek's disease vaccine viruses and of virulent oncogenic strains. In the first of four experiments, the growth of the herpes virus of turkeys (HVT) vaccine was detectable in various organs of infecte...
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PMID: 17899458
PDF is available here.
PDF is available here.
Avian Pathology (36)5 2007
Abstract
Our results reveal that the acute phase of infectious bursal disease coincides, on one hand, with high levels of systemic ChIFNgamma and chicken interleukin-6 and, on the other hand, with a strong inhibition of proliferation and activation of mitogen-stimulated splenocytes from infected chickens, as...
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PMID: 17899460
PDF is available here.
PDF is available here.
Avian Pathology (36)5 2007
Abstract
The right strategy for infectious bursal disease (IBD) control and its success rate under field conditions depends on hygiene management, IBD field pressure, level and variation in maternally derived IBD antibodies, and the IBD vaccine strains to be used. Usually, standard vaccination programmes are...
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PMID: 17899465
PDF is available here.
PDF is available here.
Avian Pathology (36)5 2007
Abstract
For this retrospective study, infectious bursal disease virus (IBDV) was detected in 134 bursal samples that originated from flocks with conditions such as airsacculitis, tracheitis, pneumonia, septicaemia, inclusion body hepatitis, coccidiosis, and/or a history of production problems without overt...
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PMID: 17899469
PDF is available here.
PDF is available here.
Abstract
We describe here a previously unrecognized cathelicidin gene in chickens, chCATH-B1, that is expressed exclusively in the epithelium of the bursa of Fabricius. Like the mature peptides of previously identified cathelicidins, the carboxyl-terminal peptide of chCATH-B1 has broad antimicrobial activity...
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PMID: 17827276
PDF is available here.
PDF is available here.
Journal of Anatomy (211)3 2007
Abstract
Our results demonstrate that the blood vessels, as major and supplying part of the lymphoid system of the bursa Fabricii, clearly reflect three different phases of development: the evolution phase from about day 20 until day 50 post-hatching, the mature phase from days 50 to 90, and the involution p...
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PMID: 17573827
PDF is available here.
PDF is available here.
Poultry Science (86)9 2007
Effect of polysavone (alfalfa extract) on abdominal fat deposition and immunity in broiler chickens.
Abstract
These results showed that polysavone may decrease abdominal fat deposition and enhance immunity without an adverse effect on the performance of broiler chickens....
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PMID: 17704384
PDF is available here.
PDF is available here.
Poultry Science (86)9 2007
Abstract
These results indicate that performance differences in gender occur with additives during different grow-out periods, and mushroom extract promotes bifidobacteria growth in broiler chickens after 4 wk of withdrawal. It appears that probiotics and mushroom extract offered no combination potential for...
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PMID: 17704371
PDF is available here.
PDF is available here.
Avian Diseases (51)3 2007
Abstract
Three hundred 1-day-old Japanese quail (Coturnix coturnix japonica) were divided into two groups of 150 each. One group was maintained on quail mash alone, whereas Fusarium verticillioides culture material (FCM) was added to quail mash in the second group from 5 days of age and supplied 150 mg FB1/k...
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PMID: 17992930
PDF is available here.
PDF is available here.
Journal of General Virology (88)Pt 8 2007
Abstract
Chicken anemia virus (CAV) is a significant immunosuppressive pathogen of chickens, but relatively little is known about the effect of specific mutations on its virulence. In order to study the virulence of CAV, an infection model was developed in embryos. Significant growth depression, measured as...
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PMID: 17622619
PDF is available here.
PDF is available here.
Abstract
These results indicate that a prime-boost approach by priming with DNA vaccine encoding the large segment gene of the IBDV and boosting with killed IBD vaccine can adequately protect SPF chickens against challenge by homologous or heterologous IBDV....
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PMID: 17561315
PDF is available here.
PDF is available here.
Abstract
B-cell activating factor (BAFF), belonging to the TNF family, is critical for B cell survival and maturation. cDNA of goose BAFF (gBAFF) was amplified from goose spleen by RT-PCR. The open reading frame (ORF) of gBAFF encodes a protein of 288-amino acid. The gBAFF shows 98, 92, 44 and 55% amino acid...
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PMID: 17482274
PDF is available here.
PDF is available here.
Abstract
The influences of avian reovirus (ARV) infection at 1 day of age on bursa development, antibody responses after vaccinations to avian influenza virus (AIV), Newcastle disease virus (NDV) and infectious bursal disease virus (IBDV), and pathogenecity of virulent IBDV (v-IBDV) were studied in chickens...
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PMID: 17672312
PDF is available here.
PDF is available here.
Avian Diseases (51)2 2007
Abstract
The maximum dosage of gamma irradiation approved by the U.S. Food and Drug Administration (FDA) for poultry is 3.0 kiloGrays (kGy). This treatment is designed to reduce bacterial contamination on uncooked poultry carcasses and meat products. The possible presence of infectious bursal disease virus (...
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PMID: 17626493
PDF is available here.
PDF is available here.
Abstract
We now find that purified primary murine OBs also support the differentiation of primitive hematopoietic stem cells through lymphoid commitment and subsequent differentiation to all stages of B-cell precursors and mature B cells. Lin(-)Sca-1(+)Rag-2(-) BM cell differentiation to B cells requires the...
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PMID: 17227831
PDF is available here.
PDF is available here.
Journal of Virology (81)8 2007
Abstract
We previously demonstrated the susceptibility of pheasants to infection with influenza A viruses of 15 hemagglutinin (HA) subtypes: 13/23 viruses tested were isolated for >or=14 days, all in the presence of serum-neutralizing antibodies; one virus (H10) was shed for 45 days postinfection. Here we co...
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PMID: 17267493
PDF is available here.
PDF is available here.
Abstract
The progression of coccidiosis provoked by Eimeria acervulina was followed in chicks fed on OTA-contaminated as well as on OTA-free diets. More heavy progress of duodenal coccidiosis, including mortality, occurred in OTA-treated chicks as can be seen from the higher value of lesion (3.50) and oocyst...
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PMID: 16997337
PDF is available here.
PDF is available here.
Veterinary Pathology (44)2 2007
Abstract
The pathogenesis of 4 isolates of turkey-origin reovirus (NC/SEP-R44/03, NC/98, TX/98, and NC/85) and 1 chicken-origin reovirus (1733) was examined by infecting specific pathogen free (SPF) poults. These turkey-origin reovirus (TRV) isolates were collected from turkey flocks experiencing poult enter...
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PMID: 17317795
PDF is available here.
PDF is available here.
Abstract
We report here that Marek's disease virus (MDV), a lymphotrophic avian alphaherpesvirus, up-regulates MHC class II cell surface expression in infected cells, contrary to all other herpesviruses examined to date. This MDV-induced class II up-regulation was detected both in vitro and in vivo. This eff...
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PMID: 17028059
PDF is available here.
PDF is available here.
Abstract
Previous studies indicated that the pathogenesis of infectious bursal disease virus (IBDV) may vary depending on the age of the infected chicken. The reason for this difference is not clear, immunopathogenesis studies comparing different age groups are lacking. In the present study the IBDV-immunopa...
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PMID: 17157923
PDF is available here.
PDF is available here.
Avian Pathology (36)1 2007
Abstract
We have observed this in Brazil, associated with diarrhoea, loss of weight gain and, commonly, high mortality. In this study, we have used the reverse transcriptase polymerase chain reaction (RT-PCR) to detect turkey coronavirus (TCoV) in sick poults 30 to 120 days of age from a particular producer...
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PMID: 17364507
PDF is available here.
PDF is available here.