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Eye Infections, Bacterial (5):
Recent article
Eye Infections, Bacterial
Abstract
Our experience based on the above and other cases suggest that CXL could be an effective tool in battling difficult cases of infectious keratitis. This treatment could present many advantages but will need further investigation....
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PMID: 21102196
PDF is available here.
PDF is available here.
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Abstract
To determine the etiologic diagnosis of infectious corneal ulcers at Tilganga Institute of Ophthalmology, a tertiary teaching hospital in Kathmandu Nepal, from 2006-2009.
This study involved a review of all microbiology records at Tilganga Institute of Ophthalmology from August 2006 through July 200...
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PMID: 20847686
PDF is available here.
PDF is available here.
Abstract
To determine the in vitro susceptibility of methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-resistant coagulase-negative Staphylococcus (MRCNS) isolates to various antibiotics.
All cases of bacterial keratitis caused by Staphylococcus species during 2006 and 2007 were identified....
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PMID: 20595899
PDF is available here.
PDF is available here.
Abstract
To identify the pathophysiological changes produced by contact lens wear that predispose the cornea to infection and search for prospective modifiable risk factors that could reduce the incidence of this critical complication in millions of patients worldwide.
Significant experimental and clinical p...
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PMID: 20622672
PDF is available here.
PDF is available here.
Abstract
We detected a subtle lagophthalmos, which was complicated by upper eyelid retraction in the right eye. A bilateral upper blepharotomy improved the keratopathy.
Patients with AIDS with severe weight loss can present with lagophthalmos because of adipose and muscular atrophy in the so-called wasting s...
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PMID: 20628297
PDF is available here.
PDF is available here.
Abstract
An 84-year-old white female with nonprogressive conjunctival scarring developed infectious crystalline keratopathy (ICK) recalcitrant to topical therapy. After determination of the causative organism's antibiotic sensitivities, superficial keratectomy was performed with intrastromal corneal infiltra...
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PMID: 20595892
PDF is available here.
PDF is available here.
Abstract
The use of topical agents poses unique and challenging hurdles for drug delivery. Topical steroids effectively control ocular inflammation, but are associated with the well-recognized dilemma of patient compliance. Although administration of topical antimicrobials as prophylaxis is acceptable among...
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PMID: 20645672
PDF is available here.
PDF is available here.
Abstract
Our purpose was to analyse the current bacterial spectrum in cLDO and to compile a bacterial resistogram in order to specify antimicrobiological therapy.
66 samples from the lacrimal duct of 6- to 16-month-old children (41 female, 25 male) were obtained by collecting the refluxing liquids with cotto...
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PMID: 20645232
PDF is available here.
PDF is available here.
Abstract
In recent years, infectious agents have been increasingly recognised as an important pathogenetic factor for various malignant tumours of the ocular adnexa. Many of these viruses and bacteria affect the cell cycle and physiological apoptosis. Ocular adnexal lymphoma (OAL), especially extranodal marg...
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PMID: 20535664
PDF is available here.
PDF is available here.
Nippon Ganka Gakkai zasshi (114)7 2010
Abstract
Recurrence of infection, negative Seidel tests, aphakia and avitreous are risk factors for visual impairment following bleb-related infection after trabeculectomy....
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PMID: 20681255
PDF is available here.
PDF is available here.
Abstract
To our knowledge, this is the first-described case of spontaneous subconjunctival abscess formation in an immunocompetent individual unrelated to preexisting ocular pathology, previous ocular surgery, or trauma. H. influenzae species may possess the ability to penetrate an intact conjunctiva and dev...
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PMID: 20489592
PDF is available here.
PDF is available here.
Abstract
A total of 61 patients were enrolled [cefazolin and tobramycin (n = 20), gatifloxacin (n = 21), and moxifloxacin (n = 20)]. Overall, 57 patients (93%) healed on treatment. On comparison of the mean time taken to heal, no statistically significant difference was found among all the 3 treatment groups...
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PMID: 20489580
PDF is available here.
PDF is available here.
Abstract
At the tertiary referral centre, 22 patients were diagnosed with pre-septal cellulitis and discharged, as were 20 cases at the district general hospital. At the tertiary referral centre, 95 per cent of patients were correctly seen by an ophthalmologist and 82 per cent by a senior ENT surgeon, compar...
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PMID: 20082744
PDF is available here.
PDF is available here.
Abstract
The ability of the ocular surface to mount an immune response is in part attributed to a family of proteins called toll-like receptors (TLRs). The latter are evolutionary conserved receptors that recognize and respond to various microbes and endogenous ligands. In addition to their recognition funct...
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PMID: 20346359
PDF is available here.
PDF is available here.
Abstract
P. aeruginosa induces keratitis in this lens-wearing model after a single inoculation. Delayed disease onset was interesting considering the greater keratitis risk during extended wear. Infection did not require the disruption of corneal barrier function before lens wear and occurred without exposur...
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PMID: 20130275
PDF is available here.
PDF is available here.
Abstract
Acute microbial keratitis incidence after intrastromal corneal ring segment implantation was 1.4%. Gram-positive cocci were the organisms isolated more frequently. Proper management of this condition requires intrastromal corneal ring segment explantation and intensive topical antibiotics.
Copyright...
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PMID: 20506994
PDF is available here.
PDF is available here.
Abstract
Fas-FasL interaction in the cornea balances the host innate immune response to improve disease outcome by promoting earlier apoptosis and regulating proinflammatory cytokines/chemokines and nitric oxide (nitrite) production. Dysregulation of this interaction contributes to bystander tissue damage, e...
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PMID: 20019368
PDF is available here.
PDF is available here.
Abstract
Abstract
We report a case of Mycobacterium abscessus keratitis after elective laser in situ keratomileusis in a 19-year-old woman. The infection started 3 weeks after uneventful surgery, and the patient received multiple antimicrobial treatments without response. A corneal scrape isolate showed an acid-fast...
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PMID: 20457379
PDF is available here.
PDF is available here.
Abstract
We report a case of endophthalmitis as a complication of Descemet's stripping with automated endothelial keratoplasty. Although a rare pathogen in endophthalmitis, M. abscessus is difficult to culture and treat. Surgical hypotony combined with contamination of intraoperative materials and/or postsur...
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PMID: 20335806
PDF is available here.
PDF is available here.
Abstract
Similar to the findings of previous studies, this study showed that fungi, especially Candida species, were the most common causative organisms of endogenous endophthalmitis. Endogenous endophthalmitis is generally associated with poor visual acuity outcomes, particularly when caused by more virulen...
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PMID: 20370344
PDF is available here.
PDF is available here.
Abstract
Bleb-associated endophthalmitis is associated with severe visual impairment. Clinical features associated with better visual outcome include early presentation, better presenting visual acuity, clear cornea at presentation, culture of a less virulent organism, and absence of diabetes mellitus....
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PMID: 20370342
PDF is available here.
PDF is available here.
Abstract
We offer a perspective on the complex pathogenesis of microbial keratitis, the factors that have prevented a better understanding of this disease, and new approaches being used to tackle this important clinical problem....
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PMID: 20190671
PDF is available here.
PDF is available here.
Abstract
We describe a 5-year-old girl who developed bilateral staphylococcal sub-Tenon's abscess resistant to fourth-generation fluoroquinolones that resolved completely after surgical drainage and irrigation with povidone iodine followed by administration of oral amoxicillin and clavulanic acid. A lost mus...
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PMID: 20304690
PDF is available here.
PDF is available here.
Abstract
Abstract
To determine the conjunctival bacterial flora in cataract surgery patients and the effect of presurgical irrigation with 5% povidone-iodine solution.
Three samples from the inferior conjunctival fornix of the eye to be operated were obtained at baseline before washing (T0) with 10 ml 5% povidone-iod...
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PMID: 20549039
PDF is available here.
PDF is available here.
Abstract
Purpose. Ulcerative keratitis due to Pseudomonas aeruginosa is a sight-threatening disease leading to loss of vision due to corneal inflammation. A human IgG1 monoclonal antibody (MAb F429) to the alginate capsule significantly reduces pathology and bacterial burdens in the cornea when applied topic...
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PMID: 19892865
PDF is available here.
PDF is available here.
Abstract
Abstract
To report successful therapy with gatifloxacin 0.3% ophthalmic solution (Zymar) in a patient with atypical mycobacterium keratitis after penetrating keratoplasty.
A 58-year-old patient was referred for evaluation of microbial keratitis after penetrating keratoplasty.
Clinical examination of the pati...
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PMID: 20164758
PDF is available here.
PDF is available here.
Abstract
In a tropical region, it is important to consider uncommon organisms such as fungi, Nocardia, and Acanthamoeba as possible etiological agents in keratitis after LASIK. A detailed microbiology work-up will help in definitive diagnosis and appropriate treatment.
Copyright 2010, SLACK Incorporated....
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PMID: 20229954
PDF is available here.
PDF is available here.
IL-33 shifts macrophage polarization, promoting resistance against Pseudomonas aeruginosa keratitis.
Abstract
These data provide evidence that IL-33 promotes a Th2-type immune response and reduces inflammation by polarizing the Mvarphi production of anti-inflammatory mediators in the cornea....
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PMID: 19892870
PDF is available here.
PDF is available here.
Abstract
Tsukamurella exhibits laboratory similarities to mycobacteria and should be considered in the differential of atypical infection of the ocular surface....
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PMID: 20098312
PDF is available here.
PDF is available here.
Abstract
Although rare, simultaneous implantation of ICRSs may carry a risk of severe bilateral infectious keratitis. Early recognition of infection, aggressive treatment with antibiotics, and, in some cases, removal of ICRSs may be necessary to prevent serious sight-threatening complication of this refracti...
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PMID: 20098317
PDF is available here.
PDF is available here.
Abstract
Twenty-four patients with a mean age of 46.4 years and a mean follow-up of 14.6 months were included. Treatment options included intravitreal antibiotics, vitrectomy, evisceration, and systemic antibiotics. Optimal structural outcome was achieved in 6 (25%) eyes. A total of 70.8% eyes had no light p...
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PMID: 19996830
PDF is available here.
PDF is available here.
Current Eye Research (35)3 2010
Abstract
All the isolates were sensitive to amikacin, azithromycin, and clarithromycin, but the MIC values of clarithromycin and azithromycin were lower than amikacin. Based on in vitro susceptibility results it appears that the topical amikacin in combination with oral clarithromycin or azithromycin is the...
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PMID: 20373881
PDF is available here.
PDF is available here.
Survey of Ophthalmology (55)3 2010
Abstract
A 52-year-old man developed transient, migratory polyarthralgias in the presence of hearing loss. He then developed persistent leukocytosis and thrombocytosis. His initial transient, bilateral visual obscurations happened in context with bilateral disk edema and an enlarged blind spot. Visual sympto...
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PMID: 20083288
PDF is available here.
PDF is available here.
Abstract
The eye may be infected from external sources or through intra-ocular invasion of micro-organisms carried by the blood stream. This study was undertaken to isolate and identify the specific bacterial pathogens causing ocular infections and to determine their in-vitro antibacterial susceptibilities t...
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PMID: 20551533
PDF is available here.
PDF is available here.
Vestnik oftalmologii (126)1 2010
Abstract
The investigation was undertaken to study changes in the structure of the vitreoretinal complex in experimental chlamydial infection. Six rabbits were inoculated with Ch. pneumonia (6 eyes) and Ch. trachomatis (6 eyes) via instillations, subconjunctivally and intravitreally. Clinical and pathomorpho...
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PMID: 20645572
PDF is available here.
PDF is available here.
Abstract
Abstract
Abstract
Abstract
Goldenhar syndrome is a rare, presumably inherited condition that has a multifactorial etiopathology that results in disturbances of blastogenesis. The syndrome is characterized by the presence of dermal epibulbar tumors, periauricular appendices, malformed ears, and vertebral anomalies, with occasi...
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PMID: 20128554
PDF is available here.
PDF is available here.
Abstract
Bacterial corneal infections threaten vision. With the widespread use of contact lenses and the increasing number of vision-correction (refractive) surgeries, the number of bacterial corneal infection (keratitis) cases has dramatically increased over the past decade. These infections...
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PMID: 21178447
PDF is available here.
PDF is available here.
Abstract
The authors investigate clinical settings, antibiotic susceptibility and resistance patterns, and visual outcomes associated with endophthalmitis caused by Stenotrophomonas maltophilia.
Records of six patients with S. maltophilia endophthalmitis between January 1, 199...
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PMID: 20873692
PDF is available here.
PDF is available here.
Abstract
Abstract
We found a synergistic effect for in vitro tests but failed to demonstrate it in vivo. When 100 microg moxifloxacin/0.1 mL is given intravitreally, it has some toxic effects that are limited to the inner retinal layers....
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PMID: 20130687
PDF is available here.
PDF is available here.
Abstract
Early pars plana vitrectomy and intravitreal vancomycin plus ceftazidime injection improved anatomic and functional success in pediatric eyes with exogenous endophthalmitis....
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PMID: 19967667
PDF is available here.
PDF is available here.
Abstract
No specimens (0%) aspirated on entry into the anterior chamber or obtained at the conclusion of surgery were positive for microorganisms on culture or eubacterial polymerase chain reaction. None of the eyes developed acute endophthalmitis. The incidence of anterior chamber bacterial contamination du...
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PMID: 19967676
PDF is available here.
PDF is available here.
Abstract
Monotherapy with moxifloxacin or gatifloxacin can be an effective alternative to cefazolin-tobramycin combination as a first-line empirical therapy for bacterial keratitis. The addition of cefazolin to a fourth-generation fluoroquinolone is of limited value....
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PMID: 19924668
PDF is available here.
PDF is available here.
Abstract
The high incidence of fungal keratitis in the studied population shows their vulnerability to such infections, which may result in devastating visual outcomes....
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PMID: 20175055
PDF is available here.
PDF is available here.
Abstract
To date, this is the second reported case of postoperative endophthalmitis by this species. Although endophthalmitis is rare, ophthalmologists should be alert to the possibility of patients having endophthalmitis caused by G morbillorum. Especially, it is necessary to be cautious with surgery in pat...
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PMID: 20037912
PDF is available here.
PDF is available here.
Abstract
We conducted a clinical retrospective study including all the consecutive cases with traumatic endophthalmitis that have been hospitalized in the University Ophthalmology Department from Cluj-Napoca (Romania), for a 28 months period of time (September the 1st 2007 - December the 31st 2009)....
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PMID: 21516871
PDF is available here.
PDF is available here.
Abstract
We report a rare presentation of periorbital cellulitis caused by B thuringiensis....
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PMID: 19882531
PDF is available here.
PDF is available here.
Abstract
Delayed presentation, rural address, and dirty wound were associated with development of endophthalmitis. Retained IOFB in association with rural address or dirty wound was associated with a particularly high risk of endophthalmitis....
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PMID: 19882538
PDF is available here.
PDF is available here.
Abstract
Rhodococcus species are rare human pathogens. Most cases of human infection have involved Rhodococcus equi, a natural zoonotic pathogen causing pneumonia in young foals. The human population at risk mainly includes immunocompromised patients. Infection of immunocompetent hosts has been rare, with le...
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PMID: 20305518
PDF is available here.
PDF is available here.
Abstract
To identify the etiology, incidence and prevalence of ocular bacterial infections, and to assess the in vitro susceptibility of these ocular bacterial isolates to commonly used antibiotics.
Retrospective analysis of consecutive samples submitted for microbiological evaluation from patients who were...
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PMID: 20952834
PDF is available here.
PDF is available here.
Abstract
We herein present four cases of isolated EOM pyomyositis. Three of our cases presented with acute onset of proptosis, pain, swelling and redness. One patient presented with mass in the inferior orbit for 4 months. One patient had central retinal artery occlusion on presentation. None of them had mar...
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PMID: 20952842
PDF is available here.
PDF is available here.
Abstract
Mycetoma is a chronic granulomatous infection. Lower extremities are commonly involved. A 20-year-old male came with complaints of multiple sinuses on scalp, left eyelid swelling with a sinus and dystopia, since one year. On examination there was relative proptosis in left eye of 2 mm. Computed tomo...
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PMID: 20029148
PDF is available here.
PDF is available here.
Abstract
We investigated the time-dependent ocular surface bacterial colonisation of sedated patients hospitalised in an intensive care unit and aimed to evaluate whether proper topical antibiotic prophylaxis could prohibit corneal infection. The study lasted 12 months and included 134 patients undergoing se...
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PMID: 20191796
PDF is available here.
PDF is available here.