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Spirochaetales Infections (3):
Recent article
Spirochaetales Infections
Abstract
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Acta Medica Okayama (63)4 2009
Human intestinal spirochetosis accompanied by human immunodeficiency virus infection: a case report.
Abstract
We present a middle-aged, heterosexual Japanese man with mixed infections including human intestinal spirochetosis, which led us to the detection of human immunodeficiency virus (HIV) infection. The patient had syphilis without related physical or neurological findings. An examination for the serum...
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PMID: 19727207
PDF is available here.
PDF is available here.
Abstract
Veterinary Microbiology (130)1-2 2008
Abstract
Bovine digital dermatitis (BDD) is a severe infectious cause of lameness which has spread through dairy cattle populations worldwide, causing serious welfare and agricultural problems. Spirochetes are the main organisms implicated and have previously proven difficult to isolate. This study aimed to...
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PMID: 18243592
PDF is available here.
PDF is available here.
Journal of Gastroenterology and Hepatology (23)7 Pt 1 2008
Abstract
Modern Pathology (21)2 2008
Abstract
We retrospectively investigated biopsy, and endoscopically or surgically resected specimens of the large intestine. Among a series of 2556 samples, 11 cases of human intestinal spirochetosis were detected (0.4%). Together with additional nine cases sporadically found, 20 cases of human intestinal sp...
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PMID: 18084255
PDF is available here.
PDF is available here.
Abstract
Nine cases (4.9%) of otosyphilis and none of Lyme disease were diagnosed by serological tests. CONCLUSION: Routine serological testing for otosyphilis, but not Lyme disease, is recommended for all cases of idiopathic, progressive sensorineural hearing loss....
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PMID: 18165003
PDF is available here.
PDF is available here.
Abstract
If intestinal spirochetosis is diagnosed to be the sole intestinal pathology in symptomatic patients, the bacteria should be eradicated with metronidazole and a colonoscopy/biopsy follow-up performed, where indicated, in patients with persisting symptoms. Significant results regarding symptoms and t...
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PMID: 17994468
PDF is available here.
PDF is available here.
Microbiology (153)Pt 12 2007
Abstract
The purpose of this study was to evaluate a multilocus sequence typing (MLST) scheme for intestinal spirochaetes of the genus Brachyspira. Eight loci mainly coding for enzymes previously used in multilocus enzyme electrophoresis analysis of Brachyspira species were examined in 66 Brachyspira field i...
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PMID: 18048921
PDF is available here.
PDF is available here.
The AIDS reader (17)11 2007
Abstract
Abstract
Our results demonstrated that intestinal spirochetosis, although rarely occurring, might play a role in chronic diarrhea and suggested a pathogenetic mechanism of intestinal spirochetosis based on the destruction of colonic microvilli and colitis histologically documented, providing additional clini...
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PMID: 17914949
PDF is available here.
PDF is available here.
Nippon rinsho. Japanese journal of clinical medicine (Suppl 5 Pt 2) 2007
Abstract
Abstract
Ten one-day-old goslings were inoculated orally with a Brachyspira alvinipulli strain isolated from the large intestine of geese that had died of intestinal spirochaetosis (Group A), 10 day-old goslings were inoculated orally with a B. hyodysenteriae strain (Group B), and a third group of 10 gosling...
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PMID: 17867459
PDF is available here.
PDF is available here.
Acta bio-medica de L'Ateneo parmense : organo della Societa di medicina e scienze naturali di Parma (78)2 2007
Abstract
Despite the fact that HIS seems to be a low prevalence infection in our area, in a strongly selected population we found 12 cases of this infection (12.12%). These results stimulate us to extend the research of intestinal spirochaetosis in the general population, when long standing gastrointestinal...
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PMID: 17933280
PDF is available here.
PDF is available here.
Journal of Medical Microbiology (56)Pt 7 2007
Abstract
These results indicate that ClpX is both conserved and immunogenic and hence might be useful as a subunit vaccine component for Brachyspira spp. infections. Sera from humans with no known exposure to B. pilosicoli reacted with the recombinant ClpX protein, indicating that it is unlikely to be useful...
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PMID: 17577058
PDF is available here.
PDF is available here.
Abstract
The aim of this study was to examine blood concentrations of amino acids, glucose and lactate in association with experimental swine dysentery. Ten pigs (approximately 23kg) were orally inoculated with Brachyspira hyodysenteriae. Eight animals developed muco-haemorrhagic diarrhoea with impaired gene...
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PMID: 17078986
PDF is available here.
PDF is available here.
Abstract
The development of intestinal lesions after inoculation with Brachyspira hyodysenteriae was followed by repeated endoscopy and biopsy sampling through a caecal cannula. Seven eight-week-old pigs were cannulated and inoculated, two were cannulated but not inoculated, and two pigs were inoculated but...
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PMID: 17023011
PDF is available here.
PDF is available here.
Abstract
We propose that this atypical spirochaete genotype should be regarded as a new species within the genus Brachyspira, and be provisionally designated 'Brachyspira suanatina' sp. nov....
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PMID: 17359270
PDF is available here.
PDF is available here.
Abstract
We observed a significant difference in the organic acid profile of diarrheal feces between pigs infected with and free from pathogenic spirochetes. Diarrhea and loose feces were collected from growing pigs, held at 15 different commercial farms. A total of 106 samples were measured for organic acid...
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PMID: 17485934
PDF is available here.
PDF is available here.
Abstract
We report a 31-year-old patient with intestinal spirochetosis. Colonoscopy revealed edematous mucosa with multiple erythematous spots in the proximal colon. Barium enema examination demonstrated marked edema with luminal narrowing and thumb-printing predominantly in the ascending colon. Numerous spi...
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PMID: 17380285
PDF is available here.
PDF is available here.
Veterinary Microbiology (119)2-4 2007
Abstract
An experiment was conducted to study the effect of diets with contrasting fermentability in the large intestine on experimental infections with Brachyspira hyodysenteriae, the causative agent of swine dysentery, and the whip worm, Trichuris suis, in pigs. Two diets with organically grown ingredients...
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PMID: 17049759
PDF is available here.
PDF is available here.
Colonic amoebiasis and spirochetosis: morphological, ultrastructural and microbiological evaluation.
Abstract
The rapid identification of E. histolytica, B. aalborgi and B. pilosicoli using traditional and specific and sensitive molecular methods permitted an accurate diagnosis and a specific therapy. It is suggested that mixed infection by parasites and spirochetes might occur more frequently than expected...
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PMID: 17201883
PDF is available here.
PDF is available here.
Abstract
Veterinary Microbiology (118)1-2 2006
Abstract
Rapid identification of porcine Brachyspira species is required in order to differentiate pathogenic from non-pathogenic species. The aim of our study was to compare a recently described genetic method based on polymerase chain reaction (PCR) and restriction fragment length polymorphism (RFLP), nox...
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PMID: 16879935
PDF is available here.
PDF is available here.
Abstract
Spirochaetes are organisms that can infect the colon of people with normal or compromised immune systems. Infected patients can present with a variety of gastrointestinal symptoms, including diarrhoea and rectal bleeding. However, some report a lack of association between specific symptoms and the p...
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PMID: 17021136
PDF is available here.
PDF is available here.
Abstract
We identified the Matsumoto isolates as B. aalborgi and diagnosed the patient with a B. aalborgi infection....
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PMID: 17085888
PDF is available here.
PDF is available here.
Abstract
These results indicate that 23S rRNA PCR-RFLP could be used as an identification method for pathogenic Brachyspira spp. (B. hyodysenteriae and B. pilosicoli) as well as an epidemiological tool for characterizing spirochetes isolated from swine....
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PMID: 16871023
PDF is available here.
PDF is available here.
Veterinary Microbiology (116)1-3 2006
Abstract
Avian intestinal spirochaetosis (AIS) is an infection of the caeca and/or colo-rectum of laying and meat breeder hens caused by anaerobic intestinal spirochaetes of the genus Brachyspira. AIS can result in a variety of symptoms, including delayed and/or reduced egg production, and increased faecal w...
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PMID: 16677782
PDF is available here.
PDF is available here.
Abstract
Histological intestinal spirochetosis appears to be relatively uncommon in Catalonia (Spain) compared to previous reports from other countries, but was identified in patients (0.7%) with chronic watery diarrhea. Sustained clinical recovery after spontaneous or drug-induced spirochetal disappearance...
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PMID: 16872318
PDF is available here.
PDF is available here.
Abstract
Traditional culture and biochemical tests (CBT) were compared with PCR for sensitivity and detection of Brachyspira hyodysenteriae and Brachyspira pilosicoli in seeded faeces and clinical samples from diarrhoeic pigs. A duplex PCR system was developed based on primers detecting the tlyA-gene of B. h...
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PMID: 16457900
PDF is available here.
PDF is available here.
Journal of Medical Microbiology (55)Pt 7 2006
Abstract
The aim of this study was to examine changes in the systemic immune response during the incubation period and following the onset of clinical swine dysentery, including the recovery period. Ten healthy conventional pigs were inoculated with Brachyspira hyodysenteriae. Blood was sampled at pre-inocul...
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PMID: 16772410
PDF is available here.
PDF is available here.
Tijdschrift voor diergeneeskunde (131)11 2006
Abstract
The objective of the present study was to determine the risk factors for swine dysentery in East-European middle-to-large sized, farrow-to-finish units, with separate breeding and grower-finisher facilities. Samples of faeces from 10 breeding animals (3-10% of the female inventory) and 10 grower fin...
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PMID: 16800228
PDF is available here.
PDF is available here.
Abstract
Griseoviridin, a known antibiotic produced by Streptomyces cacaoi subsp. cacaoi, was found to be active against Brachyspira hyodysenteriae--the bacterium causing swine dysentery. An in vitro synergism is observed when it is used in combination with viridogrisein--a simultaneously produced antibiotic...
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PMID: 16820711
PDF is available here.
PDF is available here.
Avian Pathology (35)3 2006
Abstract
There has been much confusion over the significance of spirochaetes found in the caeca of laying hens and the impact they may have on egg production. In recent years, the situation has been made clearer and the presence of such species as Brachyspira pilosicoli have been shown to cause a mild, chron...
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PMID: 16753612
PDF is available here.
PDF is available here.
Veterinary Record (158)20 2006
Abstract
Veterinary Record (158)19 2006
Abstract
Abstract
Abstract
We selectively colonized defined (altered Schaedler) flora C3H mice with either Helicobacter bilis or Brachyspira hyodysenteriae. Following selective colonization, tissues were analyzed for gross/histopathologic lesions and bacterial antigen-specific B- and T-cell responses. Gnotobiotic mice coloniz...
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PMID: 16698302
PDF is available here.
PDF is available here.
Veterinary Microbiology (113)1-2 2006
Abstract
A novel outer membrane protein-encoding gene was identified in Brachyspira hyodysenteriae. The predicted protein, SmpB, was encoded by a gene that contains regions of identity with that encoding the previously identified lipoprotein SmpA. However, the majority of the reading frame encoding SmpA and...
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PMID: 16310325
PDF is available here.
PDF is available here.
Abstract
The M-PCR is a rapid, sensitive and specific test for detecting three important enteric bacterial pathogens of pigs. SIGNIFICANCE AND IMPACT OF THE STUDY: The availability of a new diagnostic M-PCR will allow rapid detection and control of three key porcine enteric pathogens....
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PMID: 16478518
PDF is available here.
PDF is available here.
Avian Pathology (35)1 2006
Abstract
The role of Brachyspira bacteria in the aetiology of increased mortality observed in two breeder goose flocks (Flock A consisting of 1,500 and Flock B comprising 4,500 laying geese) at the end of the first egg-laying season, in the period of moulting, was studied. In Flock A 415 geese (28%) died dur...
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PMID: 16448936
PDF is available here.
PDF is available here.
Avian Pathology (35)1 2006
Abstract
Susceptibilities of predominantly Australian isolates of the pathogenic intestinal spirochaetes Brachyspira intermedia (n = 25) and Brachyspira pilosicoli (n = 17) from chickens were tested in agar dilution against four concentrations each of the antimicrobials tiamulin, lincomycin, tylosin, metroni...
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PMID: 16448937
PDF is available here.
PDF is available here.
Abstract
Lakartidningen (103)46 2006
Abstract
FEMS Microbiology Letters (197)2 2006
Abstract
Previously-developed PCR protocols specific for the 16S rRNA gene of the intestinal spirochaetes Brachyspira aalborgi and Brachyspira pilosicoli were adapted for the detection of these species in human faeces, following DNA extraction and purification using mini-prep columns. The limits of detection...
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PMID: 11313130
PDF is available here.
PDF is available here.
Abstract
A 38-year-old heterosexual male presented with a 6 to 7 week history of severe diarrhoea but no other complaints. In routine faecal cultures and routine parasitological investigations no pathogenic micro-organisms were observed. Colonoscopy revealed a normal mucosa. Multiple biopsies were obtained....
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PMID: 16398171
PDF is available here.
PDF is available here.
Abstract
This study was done to characterize diversity in 10 Brachyspira hyodysenteriae isolates in Korea. The isolates were compared with 14 well-characterized non-Korean strains of various Brachyspira species. All Korean isolates showed strong beta haemolysis and had blunt cell ends with 7-14 periplasmic f...
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PMID: 16293998
PDF is available here.
PDF is available here.
Abstract
The prevalence of Lawsonia intracellularis, Brachyspira hyodysenteriae and Salmonella spp. were investigated by multiplex PCR using fecal samples of pigs with diarrhea or a history of diarrhea. The overall herd prevalence of L. intracellularis, B. hyodysenteriae and Salmonella spp. were 46.5%, 37.2%...
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PMID: 16293991
PDF is available here.
PDF is available here.
Veterinary Microbiology (111)1-2 2005
Abstract
Brachyspira infections are significant causes of enterocolitis in pigs. In order to differentiate pathogenic species (Brachyspira (Br.) hyodysenteriae, Brachyspira pilosicoli) from less pathogenic or non-pathogenic species (Brachyspira intermedia, Brachyspira innocens, Brachyspira murdochii) in para...
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PMID: 16213113
PDF is available here.
PDF is available here.
Abstract
The aim of the present study was to survey the prevalences of the enteric pathogens Brachyspira hyodysenteriae, Brachyspira pilosicoli and Lawsonia intracellularis in Swedish growing pigs and in the Swedish wild boar population and to relate these findings to clinical signs. The study included 105 r...
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PMID: 16283917
PDF is available here.
PDF is available here.
Abstract
Abstract
A multiplex PCR assay was developed for the simultaneous detection of the etiologic agents associated with porcine proliferative enteropathies (PPE), swine dysentery (SD) and porcine salmonellosis (PS) in a single reaction using DNA from swine intestinal samples. Single and multiplex PCR amplificati...
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PMID: 16131827
PDF is available here.
PDF is available here.
Veterinary Microbiology (109)3-4 2005
Abstract
There is no ring test for quality assessment available in Europe for diagnostics and antimicrobial susceptibility testing of the fastidious, anaerobic bacteria of the genus Brachyspira. Therefore, an international ring test for Brachyspira spp. was performed once a year during 2002-2004. Two sets of...
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PMID: 15982833
PDF is available here.
PDF is available here.
Abstract
We used the epidermal suction blister technique, in conjunction with multiparameter flow cytometry, to analyze the cellular and cytokine responses elicited by intradermal injection of human volunteers with synthetic analogs for spirochetal lipoproteins and compared the responses to findings previous...
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PMID: 16085913
PDF is available here.
PDF is available here.
Abstract
Abstract
Colonic spirochetosis is a disease caused by the gram-negative bacteria Brachyspira aalborgi and Brachyspira pilosicoli. B. pilosicoli induces disease in both humans and animals, whereas B. aalborgi affects only humans and higher primates. Symptoms in humans include diarrhea, rectal bleeding, and ab...
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PMID: 16013401
PDF is available here.
PDF is available here.
Abstract
OBJECTIVE: To review the aetiologies and preventative methods associated with Jarisch-Herxheimer reactions (JHR). DATA SOURCES: Ovid Medline (1966-June Week 1 2004) was utilized to assess biomedical literature; a review of the bibliographies of articles was also performed. DATA SYNTHESIS: JHR often...
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PMID: 15896248
PDF is available here.
PDF is available here.
Abstract
We devised a nested PCR-DGGE approach to survey samples from infected root canals for the presence of members of these two phyla, and to examine their diversity. The primers used also amplified DNA from Atopobium species. Eight of 10 cases showed bands representative of the target bacterial groups....
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PMID: 15914596
PDF is available here.
PDF is available here.
Current Microbiology (50)6 2005
Abstract
The nucleotide sequence of the Brachyspira hyodysenteriae ftnA gene, encoding a putative ferritin protein (FtnA), was determined. Analysis of the sequence predicted that this gene encoded a protein of 180 amino acids. RT-PCR and Western blot showed that the ftnA gene was expressed in B. hyodysenteri...
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PMID: 15968507
PDF is available here.
PDF is available here.