Abstract
Several reports have shown that the incidence of prostate cancer is on the increase and that more men would be diagnosed of prostate cancer in the next decades. Many approaches are being applied towards reducing the cases of prostate cancer, especially in the very rich countries. How...
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PMID: 21397049
PDF is available here.
Abstract
We applied ecological statistical tools to such culture-independent data, in a novel manner, to partition taxa within the metacommunity into core and satellite species. Sputa and clinical data were obtained from 14 clinically stable adult CF patients. Fourteen rRNA gene libraries were constructed wi...
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PMID: 21151003
PDF is available here.
Abstract
We focus on two sphingolipid signaling molecules, sphingosine-1-phosphate (S1P) and ceramide, as they are involved in cell fate decisions (survival vs. apoptosis) and in a wide range of pathophysiological processes. For S1P, we will discuss sphingosine kinases and S1P lyase as the enzymes which are...
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PMID: 18751924
PDF is available here.
Abstract
We will briefly review the structure and biological effects of TNF-α, the old and recent indications of adalimumab, the pretreatment considerations, the reported adverse events and finally, the recommendations for its use in pregnancy.
2011 Prous Science, S.A.U. or its licensors. Al...
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PMID: 21573251
PDF is available here.
Abstract
To identify the best combination of serum cytokines and clinical parameters to diagnose rapidly early-onset neonatal infection (EONI) in critically ill preterm infants. At birth, most critically ill neonates are receiving broad-spectrum antibiotics pending bacterial culture results,...
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PMID: 20495505
PDF is available here.
Abstract
We proposed the classification of IAE with poor prognosis from the neuroradiological findings. Four types of encephalopathy seem to be differentiated from each other, acute necrotizing encephalopathy (ANE) type, hemorrhagic shock and encephalopathy syndrome (HSES) type, acute brain swelling (ABS) ty...
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PMID: 21400830
PDF is available here.
Abstract
We will describe some results of theses studies and propose some practical recommendations in use of the anti-TNF alpha therapy....
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PMID: 21309182
PDF is available here.
Abstract
Bronchiectasis is a complex pathology which consists of some important morphopathological changes in the lumen of the bronchi that consecutively determines recurrent pulmonary infections with a diversity of germs. The repeated episodes of infection are associated with chronic coloniz...
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PMID: 21548197
PDF is available here.
Abstract
We describe the basic methodology for producing 3D tissue-engineered skin and oral mucosa based on de-epidermised acellular human dermis, and we give examples of how these models can be used for a variety of applications....
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PMID: 21042970
PDF is available here.
Abstract
Mucormycosis is a rare life-threatening fungal infection occurring primarily in patients with diabetics or immunocompromised patients. The authors report a case of mucormycosis in a patient with diabetes complicated by bacterial brain abscess. The bacteria cultured from the abscess were Staphylococc...
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PMID: 20861715
PDF is available here.
Abstract
Diet and sedentary lifestyle, interacting with "thrifty" genes, are widely accepted as the principal cause of the current global obesity epidemic. However, a number of alternative etiologies for obesity have been proposed, including "drifty" genes, viruses, bacteria, environmental toxins, social net...
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PMID: 21119332
PDF is available here.
Abstract
We examined earlier data indicating its role in pathogenesis. We conclude that although T6S can, in rare instances, directly influence interactions with higher organisms, the broader physiological significance of the system is likely to provide defense against simple eukaryotic cells and other bacte...
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PMID: 20961764
PDF is available here.
Abstract
A survey was carried out to determine the prevalence and appropriateness of antimicrobial therapy (AMT) in the Netherlands and to identify determinants for inappropriate AMT. Prevalence surveys of patients hospitalised in the Netherlands were performed three times in 2008 and 2009. Patients' demogra...
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PMID: 21144427
PDF is available here.
Abstract
We find no evidence for such a general recommendation. As neutropenic patients and patients with rheumatoid arthritis are generally more prone to develop periprosthetic infections it can be considered in these cases to give prophylactic antibiotics before more extensive dental treatments....
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PMID: 21073830
PDF is available here.
Abstract
We recently identified a gene encoding syndecan-1 (SYN1) in microarray studies of HIV-1 infection in lymphatic tissues and show here that increased expression of SYN1 in the gut of HIV-1-infected individuals is associated with increased microbial translocation. We further show that: (1) microbial ac...
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PMID: 20700059
PDF is available here.
Abstract
Chlamydia pneumoniae was the first pathogen linked with carotid atherosclerotic changes and plaque rupture. Currently, other common pathogens are also under investigation as potential contributors.
A systematic review of PubMed and Scopus databases was performed. Stud...
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PMID: 20180770
PDF is available here.
Abstract
To investigate the influencing factors for the time of umbilical cord separation in full-term newborns.
The time of umbilical cord separation was recorded in 337 full-term newborns. Single factor and multifactor unconditioned logistic regression were performed to investigate the influencing factors...
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PMID: 21083980
PDF is available here.
Abstract
Repetitive instillation of 2 M HCL in CVCs did not cause electron microscopically detectable damage of the silicone rubber CVCs....
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PMID: 20829718
PDF is available here.
Capucine Picard,
Horst von Bernuth,
Pegah Ghandil,
Maya Chrabieh,
Ofer Levy,
Peter D Arkwright,
Douglas McDonald,
Raif S Geha,
Hidetoshi Takada,
Jens C Krause,
C Buddy Creech,
Cheng-Lung Ku,
Stephan Ehl,
László Maródi,
Saleh Al-Muhsen,
Sami Al-Hajjar,
Abdulaziz Al-Ghonaium,
Noorbibi K Day-Good,
Steven M Holland,
John I Gallin,
Helen Chapel,
David P Speert,
Carlos Rodriguez-Gallego,
Elena Colino,
Ben-Zion Garty,
Chaim Roifman,
Toshiro Hara,
Hideto Yoshikawa,
Shigeaki Nonoyama,
Joseph Domachowske,
Andrew C Issekutz,
Mimi Tang,
Joanne Smart,
Simona Eva Zitnik,
Cyrille Hoarau,
Dinakantha S Kumararatne,
Adrian J Thrasher,
E Graham Davies,
Claire Bethune,
Nicolas Sirvent,
Dominique de Ricaud,
Yildiz Camcioglu,
Júlia Vasconcelos,
Margarida Guedes,
Artur Bonito Vitor,
Carlos Rodrigo,
Francisco Almazán,
Maria Méndez,
Juan Ignacio Aróstegui,
Laia Alsina,
Claudia Fortuny,
Janine Reichenbach,
James W Verbsky,
Xavier Bossuyt,
Rainer Doffinger,
Laurent Abel,
Anne Puel and
Jean-Laurent Casanova
Abstract
We documented the clinical features and outcome of 48 patients with IRAK-4 deficiency and 12 patients with MyD88 deficiency, from 37 kindreds in 15 countries.The clinical features of IRAK-4 and MyD88 deficiency were indistinguishable. There were no severe viral, parasitic, and fungal diseases, and t...
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PMID: 21057262
PDF is available here.
Abstract
Significant advances have been made in the characterization of Vitamin D and the Vitamin D receptor (VDR) in immune function. The studies of signaling pathways involved in the response to infection and inflammation have led to a more detailed understanding of the cellular response to Vitamin D throu...
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PMID: 20639756
PDF is available here.
Abstract
Intestinal epithelium, mucosal immune system, and bacterial flora represent a morpho-functional system on dynamic balance responsible for the intestinal metabolic and trophic functions, and the regulation of mucosal and systemic host's immunity. Obesity is a pathological condition af...
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PMID: 20865475
PDF is available here.
Abstract
A class of cyclic acyldepsipeptide antibiotics collectively known as the enopeptins has recently attracted much attention because of their activity against multidrug-resistant bacteria, including methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus faecalis. These antibi...
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PMID: 20833054
PDF is available here.
Abstract
We retrospectively compared the occurrence of perioperative infection following RP between two different AMP protocols. This study included 340 cases with prostate cancer who underwent RP at our institution between January 2005 and December 2008. The 1-day group consisting of 93 cases received a sec...
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PMID: 21063159
PDF is available here.
Abstract
One of the key questions in the study of mammalian gene regulation is how epigenetic methylation patterns on histones and DNA are initiated and established. These stable, heritable, covalent modifications are largely associated with the repression or silencing of gene transcription, and when deregul...
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PMID: 20724161
PDF is available here.
Abstract
Investigators have recently turned to the soil nematode Caenorhabditis elegans as a small animal infection model to study infectious disease. To extrapolate findings concerning bacterial pathogenesis from non-mammals to mammals, virulence factors should be conserved in function, independent of the i...
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PMID: 20667738
PDF is available here.
Abstract
The bioterrorism challenge program (LPS, LPX) provides important comparative data from more than 1300 sentinel laboratories that can be used by individual laboratories to evaluate their identification and LRN reporting performance....
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PMID: 20923306
PDF is available here.
Krow Ampofo,
Amy Herbener,
Anne J Blaschke,
Caroline Heyrend,
Mark Poritz,
Kent Korgenski,
Robert Rolfs,
Seema Jain,
Maria da Glória Carvalho,
Fabiana C Pimenta,
Judy Daly,
Edward O Mason,
Carrie L Byington and
Andrew T Pavia
Abstract
We examined the relationship between circulating 2009 H1N1 and the occurrence of secondary bacterial parapneumonic empyema in children.
Children hospitalized with parapneumonic empyema from August 2004 to July 2009, including a period when the 2009 H1N1 circulated in Utah, were identified using Inte...
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PMID: 20407400
PDF is available here.
Abstract
A series of novel 1H-dibenzo[a,c]carbazole derivatives were synthesized in good yield through reaction of methyl 7-oxo-dehydroabietate with a variety of substituted phenylhydrazines. The structures of the newly synthesized compounds were confirmed by IR, (1)H NMR, MS spectral studies and elemental a...
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PMID: 20702006
PDF is available here.
Abstract
A series of novel sulfanilamide-derived 1,2,3-triazole compounds were synthesized in excellent yields via 1,3-dipolar cycloaddition and confirmed by MS, IR and NMR spectra as well as elemental analyses. All the compounds were screened in vitro for their antibacterial and antifungal activities. Preli...
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PMID: 20708826
PDF is available here.
Abstract
We reviewed cases diagnosed with SBP over a 14-year period. The medical records of 780 SBP-diagnosed patients with decompensated cirrhosis and ascites admitted to Tangdu Hospital, Xian, Shaanxi Province, China were retrospectively reviewed between January 1996 and December 2009. The patients were pl...
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PMID: 20953533
PDF is available here.
Rasmus Larsen,
Raffaella Gozzelino,
Viktória Jeney,
László Tokaji,
Fernando A Bozza,
André M Japiassú,
Dolores Bonaparte,
Moisés Marinho Cavalcante,
Angelo Chora,
Ana Ferreira,
Ivo Marguti,
Sílvia Cardoso,
Nuno Sepúlveda,
Ann Smith and
Miguel P Soares
Abstract
We demonstrate that the protective effect of this heme-catabolizing enzyme relies on its ability to prevent tissue damage caused by the circulating free heme released from hemoglobin during infection. Heme administration after low-grade infection in mice promoted tissue damage and severe sepsis. Fre...
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PMID: 20881280
PDF is available here.
Abstract
To review the role of microorganisms in interstitial lung disease (ILD) and to emphasize their importance in initiation and course of ILD.
ILD can be idiopathic but often causality such as drugs or connective tissue disease can be found. Multiple microorganisms have been associated with ILD. On the...
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PMID: 20592601
PDF is available here.
Abstract
The order Passeriformes comprises the largest number of families and species of birds of any avian order. Brazil is rich in passerine birds, which are a common victim of wildlife trafficking in Brazil. Annually, many birds die as a consequence of illegal trade. To investigate the occurrence of the p...
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PMID: 21046940
PDF is available here.
Abstract
In patients with acute pancreatitis, the absolute influence of OF and IPN on mortality is comparable and thus the presence of either indicates severe disease. The relative risk of mortality doubles when OF and IPN are both present and indicates extremely severe disease or critical acute pancreatitis...
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PMID: 20540942
PDF is available here.
Abstract
Patients with chronic liver diseases sustain impairment to immune systems, which worsens over time. These defects in their host defense lead to risks of bacterial infections and increased morbidity. Providers should have heightened surveillance for infectious diseases and suspect one with any acute...
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PMID: 20691380
PDF is available here.
Abstract
Spain could be a potential area in Europe for the development and spread of emerging diseases from the tropics due to its geoclimatic characteristics, but there is little information on infectious diseases imported by travelers. The aim of this article was to analyze clinical-epidemiological charact...
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PMID: 20920050
PDF is available here.
Abstract
We remember his life and work.
Copyright © 2010 International Society for Infectious Diseases. Published by Elsevier Ltd. All rights reserved....
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PMID: 20413340
PDF is available here.
Abstract
We demonstrate that mild travel-related gastrointestinal symptoms and the lack of arthropod bites are significantly associated with poor observance of antimalarial prophylaxis.
In this study, we suggest the complementary nature of using cohort surveys and sentinel surveillance data. Effective protec...
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PMID: 20920049
PDF is available here.
Antoni Sisó,
Manuel Ramos-Casals,
Albert Bové,
Pilar Brito-Zerón,
Natalia Soria,
Norma Nardi,
Adriana Testi,
Marta Perez-de-Lis,
Cándido Díaz-Lagares,
Alejandro Darnell,
Juan Sentís and
Antonio Coca
Abstract
We describe the natural history of lupus nephritis (LN) in a historical cohort of 190 white patients with the diagnosis of biopsy-proven LN followed in a single reference center.We evaluated 670 patients with systemic lupus erythematosus (SLE) consecutively followed in our department from 1970 until...
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PMID: 20827107
PDF is available here.
Abstract
Musculoskeletal infection is a clinical problem with significant direct healthcare costs. The prevalence of infection after closed, elective surgery is frequently estimated to be less than 2%, but in severe injuries, posttraumatic infection rates have been reported as 10% or greater. Although clinic...
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PMID: 20736799
PDF is available here.
Abstract
Local antibiotic delivery is a viable and attractive option for preventing infection. Unfortunately, the current options are limited and often necessitate surgical removal. This study evaluates the ability of a biodegradable and biocompatible chitosan sponge to minimize infection by delivering local...
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PMID: 20736801
PDF is available here.
Abstract
Untreated infection may cause stillbirth by several mechanisms, including direct fetal infection, placental damage, and severe maternal illness. Many bacteria, viruses, and protozoa have been associated with stillbirth. In developed countries, up to 24% of stillbirths have been attributed to infecti...
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PMID: 20661048
PDF is available here.
Abstract
Acute primary endodontic infections are polymicrobial infections that affect both the root canal (RC) system and apical tissues. It is known that these communities cannot be detected by conventional culturing methods. The aim of this study was to examine the profile of microbial communities in necro...
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PMID: 20728712
PDF is available here.
Abstract
We accessed findings and data from published and unpublished cefepime clinical trials.
We performed meta-analyses using trial- and patient-level data from comparative trials. Trial-level analyses were performed using summary data from all patients in the trials, and patient-level analyses were perfo...
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PMID: 20624065
PDF is available here.
Abstract
We enrolled 27 children in our study, and reviewed 692 patients reported from six major studies in Taiwan. Of the 27 patients, 15 (55.6%) had concomitant bone and joint involvement. Blood cultures were positive in 44.4% of the children in this study and 48-52% in the other studies. Pathogens could b...
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PMID: 20688294
PDF is available here.