Abstract
Our data demonstrate the contribution of GDNF to DA neuron development and may also elucidate pathogenetic mechanisms in Parkinson disease and contribute to the development of novel therapies for the disorder....
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PMID: 21865882
PDF is available here.
Abstract
Our findings showed that subsequent application of ROS scavengers improve ischemia outcomes, with melatonin being more potent. Conversely, neither melatonin, nor tempol decreased swimming speed cased by ischemia....
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PMID: 21952435
PDF is available here.
Abstract
We show that nest inheritance can explain the presence of unrelated helpers in a classic social insect model, the primitively eusocial wasp Polistes dominulus. We found that subordinate helpers produced more direct offspring than lone breeders, some while still subordinate but most after inheriting...
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PMID: 21836014
PDF is available here.
Abstract
We found that mice carrying nAChR β2-subunit deletions have impaired attention performance. Efficient lentiviral vector-mediated reexpression of functional β2-subunit-containing nAChRs in PFC neurons of the prelimbic area (PrL) completely restored the attentional deficit but did not affect impulsi...
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PMID: 21836018
PDF is available here.
Abstract
Serine proteases, serine protease inhibitors, and protease-activated receptors have been intensively investigated in the periphery and their roles in a wide range of processes-coagulation, inflammation, and digestion, for example-have been well characterized (see Coughlin, 2000; Macf...
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PMID: 21782155
PDF is available here.
Abstract
We applied capture-mark-recapture analysis to 25 years of monthly trapping data from a fluctuating prairie vole Microtus ochrogaster population in Illinois, USA, to estimate realized population growth rates and associated vital rates (survival and recruitment) and modeled them as a function of vole...
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PMID: 21905434
PDF is available here.
Abstract
In spite of its plenitude the scientific works of the important German psychologist Ernst August Dölle (1898-1972) are little adapted till today, mostly they are being reduced to his studies about dichotomy and duplicity. But on base of his diaries of the year 1968 the authors can -...
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PMID: 21837611
PDF is available here.
Abstract
Post-conflict interactions between former opponents were investigated in a troop of hamadryas baboons, Papio hamadryas. This species is known for it's multilevel structure with evidently expressed hierarchy between males and females. Due to this fact hamadryas baboons represent an id...
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PMID: 21961312
PDF is available here.
Abstract
Intranasal administration of dopamine (0.3; 3 and 30 microg/kg) on anxious behaviour of mice was studied using elevated plus-maze and open fields tests and the pinch-induced catalepsy on parallel bars test. Dopamine was introduced as nose drops or inhalation of nanoparticles of the c...
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PMID: 21961293
PDF is available here.
Abstract
Twenty resting shelters were set on the edge of a known Culiseta breeding habitat in four groups of five to support a 4 x 4 Latin square field experiment. Collection times were 0900, 1100, 1300, and 1500 hours and systematically rotated for the order by which each group of five boxes was collected. M...
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PMID: 21845953
PDF is available here.
Abstract
Objective-To assess the efficacy of a commercially available topical vapocoolant spray in reducing responses to arthrocentesis of the middle carpal (MC) and metacarpophalangeal (MCP) joints and jugular vein catheterization in unsedated horses. Animals-8 healthy research horses. Procedures-Arthrocente...
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PMID: 21627519
PDF is available here.
Abstract
Objective-To determine plasma concentrations and behavioral, antinociceptive, and physiologic effects of methadone administered via IV and oral transmucosal (OTM) routes in cats. Animals-8 healthy adult cats. Procedures-Methadone was administered via IV (0.3 mg/kg) and OTM (0.6 mg/kg) routes to each...
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PMID: 21627522
PDF is available here.
Abstract
We therefore investigated the effects of amygdala activation on somatic and visceral pain perception over the rat estrous cycle. Female Wistar rats were implanted with either corticosterone (Cort) or cholesterol as a control onto the dorsal margin of the central amygdala. Visceral sensitivity was qu...
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PMID: 21454447
PDF is available here.
Abstract
We defined the activation of noradrenergic cells during HBO exposure by c-fos immunohistochemistry. Electroencephalogram electrodes were pre-implanted in all animals under general anesthesia. In HBO seizure animals, HBO was induced with 5 atm of 100% oxygen until manifestation of general tonic convu...
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PMID: 21709713
PDF is available here.
Abstract
We tested six commercial sources of honey bees, Apis mellifera L. (Hymenoptera: Apidae), whose breeding incorporated the trait of Varroa sensitive hygiene (VSH). VSH confers resistance to the parasitic mite Varroa destructor Anderson & Trueman by enhancing the ability of the bees to hygienically remo...
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PMID: 21735889
PDF is available here.
Abstract
We tested the responses of the small southern pine engraver, Ips avulsus (Eichhoff) (Coleoptera: Curculionidae), to multiple-funnel traps baited with (+)-, (-)-, and (+/-)-ipsdienol. Three experiments were conducted in Georgia with all traps co-baited with one of the following lure combinations, res...
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PMID: 21735909
PDF is available here.
Abstract
Tens of thousands of adhesive-coated purple prism traps are deployed annually in the United States to survey for the invasive emerald ash borer, Agrilus planipennis Fairmaire (Coleoptera: Buprestidae). A reusable, more user-friendly trap is desired by program managers, surveyors, and researchers. Fie...
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PMID: 21735910
PDF is available here.
Abstract
We tracked 24 hares and 34 cottontails in a protected area of northwestern Italy. Hares were found in different sites every week, while cottontails used the same site for two weeks, and occasionally for longer. It is supposed that this periodic nest switching reduces the risk of predation and parasi...
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PMID: 21627451
PDF is available here.
Abstract
We demonstrate the potential for using virtual endocasts (VEs) to examine inter- and intraspecific variation in brain volume in members of the family Hyaenidae. Total endocranial volume (adjusted for body size) and anterior cerebrum volume (adjusted for endocranial volume) were greater in the spotte...
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PMID: 21599694
PDF is available here.
Abstract
Macroscopic renal calculi were seen in 50 of 492 (10.2 per cent) wild Eurasian otters found dead in England from 1988 to 2007. Forty-eight adults and two subadults were affected. Calculi were present in 15.7 per cent (31 of 197) of adult males and 12.7 per cent (17 of 134) of adult females. There was...
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PMID: 21676988
PDF is available here.
Andrea A Jackowski,
Tarique D TD Perera,
Chadi G CG Abdallah,
Griselda G Garrido,
Cheuk Y CY Tang,
Jose J Martinez,
Sanjay J SJ Mathew,
Jack M JM Gorman,
Leonard A LA Rosenblum,
Eric L P EL Smith,
Andrew J AJ Dwork,
Dikoma C DC Shungu,
Arie A Kaffman,
Joel J Gelernter,
Jeremy D JD Coplan and
Joan J Kaufman
Abstract
Male bonnet monkeys (Macaca radiata) were subjected to the variable foraging demand (VFD) early stress paradigm as infants, MRI scans were completed an average of 4 years later, and behavioral assessments of anxiety and ex-vivo corpus callosum (CC) measurements were made when animals were fully matur...
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PMID: 21377844
PDF is available here.
Abstract
We examined the extracellular levels of DA, behavioural deficits and the response to L-DOPA treatment in severely intoxicated mice. The MPTP intoxication produced more than a 90% reduction in tissue DA and a 65% decline in extracellular DA levels. In-vivo binding did not show any increased racloprid...
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PMID: 19262413
PDF is available here.
Abstract
We show here that establishment of select CNS longitudinal tracts and formation of precise mechanosensory afferent innervation to the same CNS region are coordinately regulated by the secreted semaphorins Sema-2a and Sema-2b. Both Sema-2a and Sema-2b utilize the same neuronal receptor, plexin B (Ple...
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PMID: 21521614
PDF is available here.
Abstract
We have found that multidendritic nociceptors in the head respond to harsh touch throughout their receptive field but respond to gentle touch only at the tip of the nose. Whereas the harsh touch response depends solely on cell-autonomous mechanosensory channels, gentle nose touch responses require f...
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PMID: 21521615
PDF is available here.
Abstract
We show that in freely behaving rats after a long period in an awake state, cortical neurons can go briefly 'offline' as in sleep, accompanied by slow waves in the local EEG. Neurons often go offline in one cortical area but not in another, and during these periods of 'local sleep', the incidence of...
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PMID: 21525926
PDF is available here.
Abstract
We generated transgenic mice expressing cDNA that encodes htt N118-82Q with the mouse prion promoter vector. In mice generated in this manner, we demonstrate robust inclusion pathology accompanied by early death and failure to gain weight. These phenotypes are the most robust abnormalities identifie...
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PMID: 21307087
PDF is available here.
Abstract
We summarize the behavioral phenotype associated with two knockout mouse models to define the role of GRs specifically within the forebrain and amygdala. We report that forebrain-specific GR knockout mice exhibit impaired negative feedback regulation of the hypothalamic-pituitary-adrenal (HPA) axis...
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PMID: 21094675
PDF is available here.
Abstract
To describe daily, hourly, and animal-to-animal effects on lying behavior in steers.
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PMID: 21453147
PDF is available here.
Abstract
To perform the modulation of an assay system for the sensory integration of 2 sensory stimuli that inhibit each other.
The assay system for assessing the integrative response to 2 reciprocally-inhibitory sensory stimuli was modulated by changing the metal ion barrier....
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PMID: 21441968
PDF is available here.
Abstract
We compared B. indica under a high-fiber diet and a standard rat diet using video monitoring. Our results show that B. indica are mainly active and feed at night, typical of nocturnal animals. A high-fiber diet resulted in a longer time to feed and become active at night and reduced the time spent f...
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PMID: 21509972
PDF is available here.
Abstract
We have shown that when E₂ was removed from embryonic zebrafish (Danio rerio) system using the aromatase inhibiter (AI) 4-hydroxyandrostenedione (4-OH-A) fish did not developmentally express normal sensory-motor (S-M) functions such as tactile, vestibular, and swimming behaviors, creating a condit...
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PMID: 21255558
PDF is available here.
Abstract
We review recent studies showing that heritable variation in these traits exists among individuals, and that they are costly to activate and maintain. We also discuss findings from genome annotation and expression studies to show how immune system-based and non-immunological defenses interact. Placi...
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PMID: 21435735
PDF is available here.
Abstract
We identified five studies which varied magnitude ratios over at least four levels and six studies in which reinforcer rate and magnitude ratios were varied factorially. The generalized matching law provided a reasonably good description of the data, accounting for 77.1% and 90.1% of the variance in...
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PMID: 21419833
PDF is available here.
Abstract
We construct a simple but biologically reasonable model based on the experimental results of two frogs, extend the model to a system of three frogs, and theoretically predict the occurrence of rich synchronization phenomena, such as triphase synchronization and 1:2 antiphase synchronization. In addi...
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PMID: 21517531
PDF is available here.
Abstract
A discrete chemotactic predator-prey model is proposed in which the prey secrets a diffusing chemical which is sensed by the predator and vice versa. Two dynamical states corresponding to catching and escaping are identified and it is shown that steady hunting is unstable. For the es...
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PMID: 21517532
PDF is available here.
Abstract
We examined synaptic plasticity and performed a comparative analysis of spatial learning, fear conditioning and step-down avoidance in wild-type mice and CNGA3 null mutants (CNGA3(-/-) ). CNGA3(-/-) mice showed normal basal synaptic transmission in the amygdala and the hippocampus. However, cornu Am...
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PMID: 20846178
PDF is available here.
Abstract
The purpose of this study was to establish a technique for collecting semen from blue-fronted Amazon parrots (Amazona aestiva aestiva) and to evaluate the samples that were collected. The massage method is the most common technique used to collect semen in birds and has been proven s...
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PMID: 21657181
PDF is available here.
Abstract
We keep can suffer has spread recently. An improved understanding of motivation, cognition and the complexity of social behaviour in animals has led in the last 30 years to the rapid development of animal welfare science. Early attempts to define welfare referred to individuals being in harmony with...
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PMID: 21347723
PDF is available here.
Abstract
We tested this hypothesis via RNA interference (RNAi) knockdown of the insulin receptor substrate (IRS) homologue, a key adaptor protein in IIS. Female larvae naturally develop into queens (reproductives) or workers (helpers) after being fed rich versus limited diets, respectively. Feeding larvae a...
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PMID: 20591854
PDF is available here.
Abstract
We tested this hypothesis via RNA interference (RNAi) knockdown of the insulin receptor substrate (IRS) homologue, a key adaptor protein in IIS. Female larvae naturally develop into queens (reproductives) or workers (helpers) after being fed rich versus limited diets, respectively. Feeding larvae a...
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PMID: 20591854
PDF is available here.
Abstract
The mechanism of pain in chronic pancreatitis (CP) has yet to be explored. Proteinase-activated receptor 2 (PAR2) plays a pronociceptive role in visceral pain. The study aimed to assess the expression of PAR2 in dorsal root ganglia (DRGs) and validate its role of thermal hyperalgesia in CP.
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PMID: 21311307
PDF is available here.
Author(s) unavailable
Abstract
The method of "low choice" of food value reinforcement depending on delayed response to its reception demonstrated various strategy of behaviour, showing short or delayed responses of pressing pedal for reception of low or high value of food reinforcement. In trained cats, multiunit activity was reco...
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PMID: 21598673
PDF is available here.
Abstract
Our findings suggest that alterations of sleep and sleep architecture during cocaine subacute and subchronic withdrawals after repeated cocaine administration may be partially involved in A(2A) receptors over-expression in the rat hypothalamus....
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PMID: 21380812
PDF is available here.
Abstract
We investigated the molecular mechanisms of the smoking cessation drug varenicline, a nicotinic acetylcholine receptor (nAChR) partial agonist, in its ability to decrease voluntary ethanol intake in mice. Previous to our study, other labs had shown that this drug can decrease ethanol consumption and...
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PMID: 21239887
PDF is available here.
Alessandro A Gozzi,
Giuliano G Turrini,
Laura L Piccoli,
Mario M Massagrande,
David D Amantini,
Marinella M Antolini,
Prisca P Martinelli,
Nicola N Cesari,
Dino D Montanari,
Michela M Tessari,
Mauro M Corsi and
Angelo A Bifone
Abstract
We used functional magnetic resonance imaging (fMRI) in the rat to map the modulatory effect of selective OXR blockade on the functional response produced by D-amphetamine, a psychostimulant and arousing drug that stimulates orexigenic activity. OXR blockade was produced by GSK1059865 and JNJ1037049...
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PMID: 21307957
PDF is available here.
Abstract
Knowledge about how frugivory and seed deposition are spatially distributed is valuable to understand the role of dispersers on the structure and dynamics of plant populations. This may be particularly important within anthropogenic areas, where either the patchy distribution of wild plants or the pr...
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PMID: 21297861
PDF is available here.
Abstract
We investigated how human activity interacted with maternal status and individual variation in behavior to affect reliability of spatially-explicit models intended to guide conservation of critical ungulate calving resources. We studied Rocky Mountain elk (Cervus elaphus) that occupy a region where...
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PMID: 21297866
PDF is available here.
S Helene SH Richter,
Joseph P JP Garner,
Benjamin B Zipser,
Lars L Lewejohann,
Norbert N Sachser,
Chadi C Touma,
Britta B Schindler,
Sabine S Chourbaji,
Christiane C Brandwein,
Peter P Gass,
Niek N van Stipdonk,
Johanneke J van der Harst,
Berry B Spruijt,
Vootele V Võikar,
David P DP Wolfer and
Hanno H Würbel
Abstract
We have recently shown in mice that standardization may generate spurious results in behavioral tests, accounting for poor reproducibility, and that this can be avoided by population heterogenization through systematic variation of experimental conditions. Here, we examined whether a simple form of...
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PMID: 21305027
PDF is available here.
Abstract
We show that many natural genotypes of D. melanogaster prefer to lay eggs near nutritious substrate, rather than in nutritious substrate. These preferences are highly polymorphic in both degree and direction, with considerable heritability (0.488) and evolvability.Relative preferences are modulated...
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PMID: 21283727
PDF is available here.
Abstract
We evaluated the immune system of BTBR mice, and compared their immunity and degree of neuroinflammation with that of C57BL/6 (B6) mice, a highly social control strain, and with F1 offspring. Mice were assessed at postnatal day (pnd) 21 and after behavioral analysis at pnd70. BTBR mice had significa...
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PMID: 21799730
PDF is available here.