Abstract
As the proportion of persons in the United States older than 65 years increases, the prevalence of dementia will increase as well. Risk factors for dementia include age, family history of dementia, apolipoprotein E4 genotype, cardiovascular comorbidities, chronic anticholinergic use,...
|
PMID: 22010769
PDF is available here.
Abstract
We conducted this study to examine the reproductive health status and depression levels of women who live in sanctuary houses after being subjected to domestic violence. The total number of women in the study is 65. Data were collected via descriptive, violence, and women's reproductive health proble...
|
PMID: 21834719
PDF is available here.
Abstract
This investigation supplements the study by D. Bouckenooghe, K. Vanderheyden, S. Mestdagh, and S. van Laethem (2007) on the role of cognitive dispositions in coping patterns for resolving decisional conflict. Literature suggests emotional vulnerabilities may significantly affect decision making. Thus...
|
PMID: 21834323
PDF is available here.
Abstract
We compared the pattern of cognitive deficits exhibited by people with schizophrenia at Allen Cognitive Level (ACL) 4 with that of people at Level 5.
|
PMID: 21834461
PDF is available here.
Abstract
Most functional neuroimaging studies of major depressive disorder (MDD) employ univariate methods of statistical analysis to localize abnormalities of neural activity. Less has been done to investigate functional relations between these regions, or with regions not usually implicated in depression. E...
|
PMID: 21764265
PDF is available here.
Abstract
In a four-wave, cohort-longitudinal design with a community sample of 515 children and adolescents (grades 2 through 9), this study examined the longitudinal structure of and prospective interrelations between maladaptive cognitions and depressive symptoms. Multigroup structural equation modeling gen...
|
PMID: 21823760
PDF is available here.
Abstract
Little is known about the impact of comorbid psychiatric symptoms in health related quality of life (HRQL) in patients with HIV infection. The aim of this investigation was to describe depressive symptoms and the impact in HRQL in HIV infected people.
|
PMID: 21845794
PDF is available here.
Abstract
Major depressive disorder, the most common psychiatric illness, is often chronic and a major cause of disability. Many patients with major depressive episodes who have an underlying but unrecognized bipolar disorder receive pharmacologic treatment with ineffective regimens that do no...
|
PMID: 21810644
PDF is available here.
Abstract
quality of life was reduced in both behavioural groups compared with participants without either condition. Disability was greater in the group with apathy. Variation in disability score (56%, P < 0.001) was explained by greater levels of apathy, depression, motor impairment and longer disease dur...
|
PMID: 21788252
PDF is available here.
John C Breitner,
Laura D Baker,
Thomas J Montine,
Curtis L Meinert,
Constantine G Lyketsos,
Karen H Ashe,
Jason Brandt,
Suzanne Craft,
Denis E Evans,
Robert C Green,
M Saleem Ismail,
Barbara K Martin,
Michael J Mullan,
Marwan Sabbagh,
Pierre N Tariot and
ADAPT Research Group
Abstract
We continued the double-masked ADAPT protocol for 2 additional years to investigate incidence of AD (primary outcome). We then collected cerebrospinal fluid (CSF) from 117 volunteer participants to assess their ratio of CSF tau to Aβ(1-42.)
Including 40 new events observed during fo...
|
PMID: 21784351
PDF is available here.
Abstract
To compare the effects of haloperidol, amisulpride, olanzapine, quetiapine, and ziprasidone on hostility in first-episode schizophrenia, schizoaffective disorder, or schizophreniform disorder.
|
PMID: 21824456
PDF is available here.
Abstract
Personality factors have shown to be related to mortality, morbidity, and psychological aspects in chronic disorders. Little is known about the effect of personality on disease severity in sarcoidosis and idiopathic pulmonary fibrosis (IPF). The aim of this study was to assess the pr...
|
PMID: 21796893
PDF is available here.
Abstract
We examined whether perceived discrimination, which has been associated with poor mental health in prior research, contributes to greater depression and PTSD symptoms among HIV-positive Black men who have sex with men (MSM), who are at high risk for discrimination from multiple stigmatized character...
|
PMID: 21787061
PDF is available here.
Abstract
We aimed to identify the neural substrates associated with emotional lability that were distinct from impairments in cognitive control and to assess the effects that stimulants have on those substrates. We used functional magnetic resonance imaging (fMRI) to assess neural activity in adolescents wit...
|
PMID: 21778039
PDF is available here.
Abstract
We examined the relation of maternal history of depression to individual differences in theory of mind in a sample of adult women. Sixty-one depressed women (23% with a positive maternal history of depression) and 30 non-depressed women (33% with a positive maternal history of depression) completed...
|
PMID: 21733579
PDF is available here.
Abstract
The present study was to examine the efficacy of Telephone-based intervention (TBI) with alcohol abusers.
Sixty individuals suffering from alcohol abuse were randomly assigned to either the intervention group (n=30) (in which the TBI was modified based on the combinat...
|
PMID: 21774293
PDF is available here.
Abstract
The well-established relationship between childhood adversity and psychosis is likely to involve other factors such as genetic variants that can help us to understand why not everyone exposed to adverse events develops psychotic symptoms later in life.
|
PMID: 21719879
PDF is available here.
Abstract
These results suggest that positive world assumptions and better social functioning during training may protect police officers from critical incident related PTSD....
|
PMID: 21095622
PDF is available here.
Abstract
One of the common symptoms of dementia is delusions. Due to a biological conceptualization of the behaviors represented as delusions, these are classified as psychotic symptoms. This is a qualitative and quantitative study aiming to describe the delusions experienced by older persons with dementia an...
|
PMID: 21669463
PDF is available here.
Abstract
A growing body of research suggests that deficient emotional self-regulation (DESR) is prevalent and morbid among patients with attention deficit hyperactivity disorder (ADHD). Family studies provide a method of clarifying the co-occurrence of clinical features, but no family studies have yet address...
|
PMID: 21498464
PDF is available here.
Priya P Wickramaratne,
Marc J MJ Gameroff,
Daniel J DJ Pilowsky,
Carroll W CW Hughes,
Judy J Garber,
Erin E Malloy,
Cheryl C King,
Gabrielle G Cerda,
A Bela AB Sood,
Jonathan E JE Alpert,
Madhukar H MH Trivedi,
Maurizio M Fava,
A John AJ Rush,
Stephen S Wisniewski and
Myrna M MM Weissman
Abstract
Maternal major depressive disorder is an established risk factor for child psychopathology. The authors previously reported that 1 year after initiation of treatment for maternal depression, children of mothers whose depression remitted had significantly improved functioning and psychiatric symptoms....
|
PMID: 21406462
PDF is available here.
Abstract
After adjusting for potential confounders, lifetime experience of two or more psychotic symptoms was associated with lifetime use of cocaine (AOR 1.94; 95% CI 1.10-3.45) and psychedelics (AOR 2.37; 95% CI 1.20-4.66). Additionally, when mood or anxiety disorders were excluded, lifetime experience...
|
PMID: 21054283
PDF is available here.
Abstract
Attention deficit/hyperactivity disorder (ADHD) can sometimes coexist with bipolar disorder (BD). Despite controversies about the coexistence of the two disorders, recent clinical as well as biological studies support the concept of comorbid adult ADHD and BD. Although there is some overlapping sympt...
|
PMID: 21717696
PDF is available here.
Abstract
Negative symptoms have clear functional implications in schizophrenia and are typically unresponsive to current treatments. The cognitive model of negative symptoms suggests that dysfunctional beliefs are influential in the development and maintenance of negative symptoms and schizophrenia. The curre...
|
PMID: 21704387
PDF is available here.
Abstract
Panic is commonly co-morbid with schizophrenia. Panic may emerge prodromally, contribute to specific psychotic symptoms, and predict medication response. Panic is often missed due to agitation, impaired cognition, psychotic symptom overlap and limited clinician awareness. Carbon dioxide exposure has...
|
PMID: 21719111
PDF is available here.
Abstract
The purpose of this study is to compare the efficacy of olanzapine and risperidone for the acute treatment of first-episode schizophrenia patients with cannabis use disorders. This secondary analysis of a previously published study included 49 first-episode patients with a diagnosis...
|
PMID: 21636134
PDF is available here.
Abstract
This study describes the characteristics of children suffering from attention deficit/hyperactivity disorder (ADHD) symptoms and evaluates the ability of primary health care to assess ADHD. A population of 494 children was referred during one year to the outpatient clinic Child and A...
|
PMID: 21621851
PDF is available here.
Abstract
The dysfunctional behavior of excessive Internet gamers, such as preferring the immediate reward (to play World of Warcraft) despite the negative long-term consequences may be comparable with the dysfunctional behavior in substance abusers or individuals with behavioral addictions, e...
|
PMID: 21641048
PDF is available here.
Abstract
preoperatively, plasma esterase activity was significantly lower in patients who developed delirium compared with the remaining subjects. Following surgery BuChE activity was lower in the delirium group but this difference disappeared after controlling for preoperative values. Plasma cholinesterase...
|
PMID: 21576115
PDF is available here.
Abstract
We found that 8% (n=33) reported current sexual orientation obsessions and 11.9% (n=49) endorsed lifetime symptoms. Patents with a history of sexual orientation obsessions were twice as likely to be male than female, with moderate OCD severity. Time, interference, and distress items from the YBOCS o...
|
PMID: 21094531
PDF is available here.
Abstract
Studies of individuals at ultra high risk (UHR) for psychosis have revealed deviations in cognitive and neural development before the onset of psychosis. As affective impairments are among the core dysfunctions in psychotic disorders such as schizophrenia, this study assessed emotion processing and t...
|
PMID: 21094533
PDF is available here.
Jocelyn J Catty,
Sarah S White,
Marsha M Koletsi,
Thomas T Becker,
Angelo A Fioritti,
Rana R Kalkan,
Christoph C Lauber,
Pascale P Lissouba,
Wulf W Rössler,
Toma T Tomov,
Jooske T JT van Busschbach,
Durk D Wiersma,
Tom T Burns and
Abstract
We aimed to determine predictors of good relationships, using data from an international randomized controlled trial of supported employment (n=312). Baseline predictors of early therapeutic relationships with vocational workers were assessed, along with the impact of vocational status and changing...
|
PMID: 21094532
PDF is available here.
Abstract
We explored the extent to which childhood abuse (physical or sexual), variants of a main glucocorticoid receptor (GR) polymorphism (Bcl1), or their interaction, differentiated women with and without BN. Women seeking treatment for BN (N=129) and non-eating-disordered comparison women (N=98) provided...
|
PMID: 21093928
PDF is available here.
Marte M Tandberg,
Torill T Ueland,
Kjetil K Sundet,
Ulrik U Haahr,
Inge I Joa,
Jan Olav JO Johannessen,
Tor Ketil TK Larsen,
Stein S Opjordsmoen,
Bjørn Rishovd BR Rund,
Jan Ivar JI Røssberg,
Erik E Simonsen,
Per P Vaglum,
Ingrid I Melle,
Svein S Friis and
Thomas T McGlashan
Abstract
Neurocognitive deficits are a core feature of schizophrenia that is associated with poor occupational functioning. Few studies have investigated this relationship in patients with first-episode psychosis. The current study examined the characteristics of employed and unemployed patie...
|
PMID: 21575993
PDF is available here.
Abstract
Dizzy patients with both psychological and physical symptoms tend to have high levels of disability and are at risk of remaining symptomatic and disabled. The objective of this study was to develop a prediction model for the presence of anxiety and/or depression in older dizzy patients in primary car...
|
PMID: 21546650
PDF is available here.
Abstract
These data suggest that in the long term, DBS remains a safe and effective treatment for treatment-resistant depression. Additional trials with larger samples are needed to confirm these findings....
|
PMID: 21285143
PDF is available here.
Lara C LC Foland-Ross,
Paul M PM Thompson,
Catherine A CA Sugar,
Sarah K SK Madsen,
Jim K JK Shen,
Conor C Penfold,
Kyle K Ahlf,
Paul E PE Rasser,
Jeffrey J Fischer,
Yilan Y Yang,
Jennifer J Townsend,
Susan Y SY Bookheimer and
Lori L LL Altshuler
Abstract
Using a technique that is highly sensitive to subtle neuroanatomical differences, significant regional cortical thinning was found in lithium-free euthymic patients with bipolar disorder....
|
PMID: 21285139
PDF is available here.
Abstract
Both suicidal and nonsuicidal self-harm persisted in depressed adolescents receiving treatment in the ADAPT study. A history of nonsuicidal self-injury prior to treatment is a clinical marker for subsequent suicide attempts and should be as carefully assessed in depressed youths as current suicidal...
|
PMID: 21285141
PDF is available here.
Abstract
Transcranial magnetic stimulation (TMS) effectiveness in major depression has so far been studied mainly with high-frequency (>1 Hz) administration (HF-TMS). However, some available studies with low-frequency TMS (LF-TMS) have provided similar response rates to HF-TMS with better tolerance, but the e...
|
PMID: 21093060
PDF is available here.
J Hampton JH Atkinson,
Hua H Jin,
Chuan C Shi,
Xin X Yu,
Nichole A NA Duarte,
Corinna Young CY Casey,
Donald R DR Franklin,
Ofilio O Vigil,
Lucette L Cysique,
Tanya T Wolfson,
P Katie PK Riggs,
Saurabh S Gupta,
Scott S Letendre,
Thomas D TD Marcotte,
Igor I Grant,
Zunyou Z Wu,
Robert K RK Heaton and
Abstract
China's HIV epidemic commenced in its agrarian provinces through contaminated commercial plasma donation centers and is now becoming a public health concern nationwide. Little is known of the psychiatric and substance use disorder characteristics of this population, or their impact on everyday functi...
|
PMID: 21094530
PDF is available here.
Abstract
Psychosis is broadly defined as the presence of delusions and hallucinations. It can be organic or functional. The former is secondary to an underlying medical condition, such as delirium or dementia, the latter to a psychiatric disorder, such as schizophrenia or bipolar disorder. The identification...
|
PMID: 21714473
PDF is available here.
Abstract
We conclude that CRT leads to measurable physiological adaptation associated with improved cognitive ability. Trial name: Cognitive Remediation Theraphy and Schizophrenia. http://clinicaltrials.gov/ct2/show/NCT01078129. Registration number: NCT01078129....
|
PMID: 21543191
PDF is available here.
Abstract
We investigated the relationship between pretreatment EEG and early improvement in predicting clinical outcome in 72 MDD subjects across three placebo-controlled treatment trials. Subjects were randomized to receive fluoxetine, venlafaxine, or placebo. Theta current density in the rACC and mOFC was...
|
PMID: 21546222
PDF is available here.
Abstract
We aimed to assess the association between core cerebrospinal fluid (CSF) biomarkers, regional brain atrophy and clinical severity in the Alzheimer's disease (AD) continuum, as well as to investigate how cognitive reserve (CR) may modulate these putative associations. Forty-nine subjects (11 controls...
|
PMID: 21546220
PDF is available here.
Abstract
Our results suggest preserved hippocampal size in women with schizophrenia during the first years of illness....
|
PMID: 21546218
PDF is available here.
Abstract
We explored ideal, ought, and feared body image self-discrepancies as predictors of social physique anxiety within Carver, Lawrence, and Scheier's and Woodman and Hemmings' interaction frameworks. One hundred women completed actual, ideal, ought, and feared body self-discrepancy visual analogue scale...
|
PMID: 21492139
PDF is available here.
Abstract
Our study suggests that the gray matter volume and density of limbic structure decreased in recent onset PTSD patients who were exposed to extreme trauma. PTSD symptom severity was associated with gray matter density in calcarine cortex and hippocampus....
|
PMID: 21498053
PDF is available here.
Abstract
We therefore investigated the cerebral correlates of NSS by using magnetic resonance imaging (MRI) in 102 patients with first episode schizophrenia. NSS were assessed after remission of acute psychotic symptoms using the Heidelberg scale (HS), which consists of five NSS subscales ("motor coordinatio...
|
PMID: 21498055
PDF is available here.
Abstract
We used structural magnetic resonance imaging (MRI) to study 37 depressed and 27 healthy control subjects to show that prevalence of WMH T2-WI is higher in depressed patients and that severity of depression and cognitive impairment is associated with presence of WMH T2-WI in basal ganglia. The occur...
|
PMID: 21482458
PDF is available here.
Abstract
We assessed the relationship between clinically assessed premorbid function, and cortico-striatal activity during sustained attention in controls (HC: with no family history of psychosis) and SCZ-Off. Subjects (n=39) were assessed using the Structured Interview for Prodromal Syndromes and the Scale...
|
PMID: 21497490
PDF is available here.
Abstract
We investigated the mechanisms that underpin the modulation of affect in bipolar disorder to examine the contributions of cortico-limbic brain networks in the processing of affect. We employed a simultaneous functional magnetic resonance imaging and galvanic skin response methodology to investigate...
|
PMID: 21493046
PDF is available here.
Abstract
We investigated Single Nucleotide Polymorphism (SNP) and haplotype association of three candidate genes of the three enzymes involved in this metabolism. The three genes, namely, tryptophan hydroxylase 2 (TPH2), kynurenine 3 monooxygenase (KMO) and kynurenine amino transferase 3 (KAT III) SNPs and h...
|
PMID: 21492941
PDF is available here.
Abstract
We examined the interrelationships among number of distinct traumatic event exposures, PTSD diagnosis, physical health, and substance use behavior using epidemiological data from the National Comorbidity Survey Replication (NCS-R; Kessler et al., 2004). Results provide some evidence that PTSD mediat...
|
PMID: 21481478
PDF is available here.
Abstract
We examined the hypothesis that women suffering with MD in pregnancy would have relatively increased cortisol secretion, a time-advanced rise in placental CRH production and an earlier delivery of the baby....
|
PMID: 21093926
PDF is available here.
Abstract
The authors conducted a randomized, placebo-controlled study of nicotine replacement therapy for the reduction of agitation and aggression in smokers with schizophrenia.
|
PMID: 21245085
PDF is available here.
Abstract
Previous anatomic studies have established a reduction in hippocampal volume in schizophrenia, but few have investigated the progressive course of these changes and whether they are trait markers. In the present study, the authors examined hippocampal volumes in relation to age for patients with chil...
|
PMID: 21245087
PDF is available here.
Abstract
The impact of hormonal fluctuation during the menstrual cycle on the course of bipolar disorder is poorly understood. The authors determined the course of illness and time to relapse of bipolar disorder in prospectively followed women with premenstrual exacerbation.
|
PMID: 21324951
PDF is available here.
Abstract
It has been suggested that illness perceptions in mental health are related to treatment outcomes.
|
PMID: 20854175
PDF is available here.