Abstract
Postmenopausal women make up one of the fastest growing populations in the United States. Women typically have a higher incidence of cardiovascular disease following menopause. One of the major risk factors for cardiovascular disease is hypertension, and after menopause, blood pressu...
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PMID: 21463249
PDF is available here.
Abstract
The use of low-dose aspirin for primary prevention of cardiovascular events in patients with diabetes is recommended by existing guidelines, but definitive evidence supporting its efficacy is lacking. The authors undertook a meta-analysis of published trials to determine the effect of low-dose aspir...
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PMID: 21191260
PDF is available here.
Abstract
The first part of the chapter describes the Icelandic Genealogical Database, how it was created, what it contains, and how it operates. In the second part, an overview of research accomplished with material from the database is given.
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PMID: 20949392
PDF is available here.
Abstract
Chronic kidney disease (CKD) is characterized by the progressive retention of a myriad of compounds, several of which play a role in cardiovascular damage, a major cause of mortality in CKD. Over the past years, especially protein-bound compounds (e.g. indoxylsulfate and p-cresylsulfate) and/or midd...
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PMID: 20938131
PDF is available here.
Abstract
The objective of the present study was to compare whole pea flour (WPF) to fractionated pea flour (FPF; hulls only) for their ability to reduce risk factors associated with CVD and diabetes in overweight hypercholesterolaemic individuals. Using a cross-over design, twenty-three hypercholesterolaemic...
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PMID: 20807459
PDF is available here.
Abstract
We randomised healthy non-smoking postmenopausal women to consume a buttered roll with and without tomato purée (70 g) in a cross-over design. Endothelial-dependent flow-mediated dilation (FMD) and endothelial-independent nitro-mediated dilation of the brachial artery were assessed with high-resolu...
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PMID: 20735877
PDF is available here.
Abstract
Hypercholesterolemia is a major risk factor for cardiovascular diseases. Serumcholesterol concentrations are regulated by enteral absorption and hepatic synthesis. Statins inhibit the rate-limiting enzyme of endogenous cholesterol synthesis, HMG-CoA-reductase and reduce serum cholesterol concentrati...
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PMID: 21181614
PDF is available here.
Abstract
We can distinguish: the male sex, race, overweight and obesity, thyroid hypofunction, age and alcohol abuse. Obstructive sleep apnea results in the absence (apnea) or reduction (hypopnea) of airflow lasting at least 10 s despite normal respiratory exertion. The apnea and hypopnea result in decreased...
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PMID: 21190150
PDF is available here.
Alan D Bell,
André Roussin,
Raymond Cartier,
Wee Shian Chan,
James D Douketis,
Anil Gupta,
Maria E Kraw,
Thomas F Lindsay,
Michael P Love,
Neesh Pannu,
Rémi Rabasa-Lhoret,
Ashfaq Shuaib,
Philip Teal,
Pierre Théroux,
Alexander G G Turpie,
Robert C Welsh,
Jean-François Tanguay and
Canadian Cardiovascular Society
Abstract
We provide specific guidelines for secondary prevention in patients discharged from hospital following acute coronary syndromes, post-percutaneous coronary intervention, post-coronary artery bypass grafting, patients with a history of transient cerebral ischemic events or strokes, and patients with...
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PMID: 21640290
PDF is available here.
Abstract
The objective of this study was to determine if gene-environment interactions between cigarette smoking and interleukin-6 (IL6), interferon-γ (IFNG), interleukin-1β (IL1B), or interleukin-1 receptor antagonist (IL1RN) single nucleotide polymorphisms are associated with lung functio...
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PMID: 21814463
PDF is available here.
Abstract
Four and a half LIM domains protein 1 (FHL1) and FHL2, as the name suggests, contain four and a half LIM domain binding proteins. Proteins in this family capable of interacting with many types of proteins, including structural proteins, kinases, and several classes of transcription f...
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PMID: 21539754
PDF is available here.
Abstract
We developed a model to examine cardiometabolic plasticity (i.e., changes in Si and plasma lipids) in MA compared to NHW adults in response to a diet-exercise intervention.
Sedentary subjects (20 NHW: 11F, 9M, 23.0 y, 25.5 kg/m(2); 17 MA: 13F, 4M, 22.7 y, 25.4 kg/m(2)) consumed their...
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PMID: 21364957
PDF is available here.
Abstract
We sought to compare the predictive value of various lipid measures for coronary events and to further examine the incremental value of novel lipid parameters over traditional cardiovascular risk factors in estimating cardiac risk.
We performed a post-hoc analysis of the National Hea...
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PMID: 21392721
PDF is available here.
Abstract
Diabetes-induced micro- and macrovascular complications are the major causes of morbidity and mortality in diabetic patients. While hyperglycemia is a key factor for the pathogenesis of diabetic microvascular complications, it is only one of the multiple factors capable of increasing...
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PMID: 21453786
PDF is available here.
Abstract
Metabolic syndrome (MetS), cardiovascular diseases (CVD) and cancers such as colon cancer (CCa), prostate cancer (PCa) and breast cancer (BCa) have been recognized as obesity-initiated diseases. The development of obesity can cause changes in metabolic and hormonal conditions, which...
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PMID: 21392470
PDF is available here.
Abstract
We examined EPC numbers in 37 type 1 diabetic patients with DN and 35 type 1 diabetic patients with long-standing normoalbuminuria. Patients were without symptoms of CVD and the prevalence of CVD was previously shown to be very low. EPC number was assessed in in vitro cultures by fluorescent stainin...
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PMID: 21252582
PDF is available here.
Abstract
We hypothesized that the functional KL-VS and the exonic C1818T variants of Klotho gene may be associated with ischemic stroke in Indian population. We enrolled a total of 460 patients with ischemic stroke and 574 age- and gender-matched controls for the study. Genotyping was done by polymerase chai...
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PMID: 21093413
PDF is available here.
Abstract
We discuss here some recent advances in the endovascular field. Technical aspects of sub-intimal vs intraluminal recanalisation will be discussed, focusing on the different kinds of devices (e.g. crossing, reentry, debulking devices) actually at the interventionist's disposal. As endovascular techni...
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PMID: 21145678
PDF is available here.
Abstract
We hypothesized that early neuronal and delayed inducible nitric oxide synthase blockade attenuates multiple organ dysfunctions during sepsis.
Sheep were randomly allocated to sham-injured, nontreated animals (n = 6); injured (48 breaths of cotton smoke and instillation of Pseudomonas aeruginosa int...
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PMID: 21068663
PDF is available here.
Abstract
Recent evidence suggests that lower HDL-cholesterol (HDL-C) may worsen the atherosclerotic process by promoting inflammation and progression from subclinical lesion to clinical event. Carotid intima-media thickness (CIMT) is recognized as a marker of early atherosclerosis and used to...
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PMID: 21830454
PDF is available here.