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Welcome to the Pubget Medical Subject Headings (MESH) browser. Click on a topic or subtopic below to explore related papers. In the gold box is the most recent paper about the current MESH term, and below are 20 related papers.
Blood Vessels (9):
Recent article
Blood Vessels
Abstract
Tissue engineering promises to restore tissue and organ function following injury or failure by creating functional and transplantable artificial tissues. The development of artificial tissues with dimensions that exceed the diffusion limit (1-2 mm) will require nutrients and oxygen...
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PMID: 21892744
PDF is available here.
PDF is available here.
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Abstract
The aim of the study was to construct small-diameter vascular grafts using canine mesenchymal stem cells (cMSCs) and a pulsatile flow bioreactor. cMSCs were isolated from canine bone marrow and expanded ex vivo. cMSCs were then seeded onto the luminal surface of decellularized arteri...
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PMID: 21784877
PDF is available here.
PDF is available here.
Abstract
We employed EPCs seeded in PCL scaffold with surface-immobilized heparin and vascular endothelial growth factor (VEGF). EPCs seeded on scaffolds with VEGF exhibited phosphorylation of the receptor. After 7 days of subcutaneous implantation in immunodeficient mice, heparin-immobilized PCL scaffolds w...
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PMID: 21395445
PDF is available here.
PDF is available here.
Abstract
Our 3-month study in nondiabetic hypertensive patients showed a decrease in biomarkers of IR and chronic systemic inflammation with the PIO monotherapy and the PIRA combination only, which may help to explain some findings in other cardiovascular outcome trials.
© 2011 Diabetes Tech...
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PMID: 21880242
PDF is available here.
PDF is available here.
Abstract
Our 3-month study in nondiabetic hypertensive patients showed a decrease in biomarkers of IR and chronic systemic inflammation with the PIO monotherapy and the PIRA combination only, which may help to explain some findings in other cardiovascular outcome trials.
© 2011 Diabetes Tech...
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PMID: 21880242
PDF is available here.
PDF is available here.
Journal of Immunotherapy (34)3 2011
Abstract
We investigated the molecular mechanism of the effects of this combination therapy on melanoma tumor growth. In B16 tumor-bearing mice, the addition of IFN-α to DTIC treatment significantly reduced tumor volume, compared with control or DTIC alone. Consistently, Digital Radiography data showed less...
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PMID: 21389866
PDF is available here.
PDF is available here.
Integrative Biology (3)4 2011
Abstract
We recently reported that apolipoprotein A-I (apoA-I) and apoA-I mimetic peptides inhibit tumor growth and improve survival in a mouse model of ovarian cancer. The current study was designed to examine whether inhibition of angiogenesis is one of the mechanisms for the observed anti-tumorigenic effe...
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PMID: 21283904
PDF is available here.
PDF is available here.
Integrative Biology (3)4 2011
Abstract
We describe the design, production and characterization of a novel immunocytokine, in which murine interferon-alpha2 was sequentially fused with the tumor-targeting antibody fragment scFv(F8), specific to the alternatively-spliced EDA domain of fibronectin. The resulting fusion protein (F8-IFNa) cou...
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PMID: 21225052
PDF is available here.
PDF is available here.
Abstract
To test whether obese children with non-alcoholic fatty liver disease have impaired vascular function compared with obese children with normal liver fat content.
Obese children (n = 28, 16 males, mean age 10.9 ± 0.7 years, body mass index [BMI] 31.9 ± 4.5 kg/m(2)) w...
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PMID: 20950125
PDF is available here.
PDF is available here.
Abstract
Total atherosclerotic occlusions often include significant calcium deposits. Current animal models do not mimic the pathology of gradual occlusion of arteries and lack cell-mediated calcium. The primary goal of this project was to establish an animal model incorporating these feature...
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PMID: 20827712
PDF is available here.
PDF is available here.
Journal of Proteomics (74)4 2011
Abstract
Assessing protein changes in the cerebral vasculature of brain disorders may increase our understanding of disease pathogenesis and facilitate diagnostic and therapeutic intervention. By combining perfusion of mice with a charged reactive biotin derivative and subsequent quantificati...
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PMID: 21262399
PDF is available here.
PDF is available here.
Cell Cycle (10)4 2011
Abstract
SIRT1 is a NAD (+) -dependent class III histone deacetylase (HDAC) that mediates the effects of caloric restriction on lifespan and metabolic pathways in various organisms. It deacetylates both histone and non-histone proteins, and targets proteins with diverse cellular and tissue fu...
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PMID: 21293192
PDF is available here.
PDF is available here.
Cell Cycle (10)3 2011
Abstract
Developmental Cell (20)1 2011
Abstract
We performed a protein-protein interaction screen with the Robo4 extracellular domain. We find that Robo4 specifically binds to UNC5B, a vascular Netrin receptor, revealing unexpected interactions between two endothelial guidance receptors. We show that Robo4 maintains vessel integrity by activating...
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PMID: 21238923
PDF is available here.
PDF is available here.
Abstract
Total laparoscopic hysterectomy (LH) is a minimally invasive technique, which results in comparable morbidity and better cosmesis compared with total abdominal hysterectomy. The literature is discrepant as to whether it is associated with a higher incidence of positive peritoneal cytology compared w...
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PMID: 21164295
PDF is available here.
PDF is available here.
Abstract
Abstract
We identified the chicken chorioallantoic membrane (CAM) as a model system to study the endogenous function of TEM8 in blood vessels as we found that TEM8 expression was induced transiently between day 10 and 12 of embryonic development, when the vascular tree is undergoing final development and gro...
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PMID: 21829615
PDF is available here.
PDF is available here.
Abstract
We show that SDF-1 and VEGF, which are produced by tumors, increase Dll4 expression on recruited BM-VPC. Mechanistically, BM-VPC activated, in a Dll4-dependent manner, a transcriptional program on mature EC suggestive of EC activation and stabilization. BM-VPC induced ICAM-2 and Fibronectin expressi...
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PMID: 21483741
PDF is available here.
PDF is available here.
Abstract
Modular tissue engineering is a means of building functional, vascularized tissues using small (∼1 mm long×0.5 mm diameter) components. While this approach is being explored for its utility in adipose and cardiac tissue engineering and in islet transplantation, the initial que...
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PMID: 20695789
PDF is available here.
PDF is available here.
Abstract
We have generated a zebrafish line carrying a stop mutation in the kinase domain of the Tie-2 receptor. Mutant embryos lack Tie-2 protein, but do not display any defect in heart and vessel development. Simultaneous loss of Tie-1 and Tie-2, however, leads to a cardiac phenotype. Our study shows that...
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PMID: 21045210
PDF is available here.
PDF is available here.
Abstract
Although Klippel-Trénaunay syndrome is a mixed vascular malformation characterized by abnormal growth in the extremities, no uniform diagnostic criteria have been established because of the variety in its manifestation. Consequently, no anatomical analysis based on a comparison study has been repor...
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PMID: 21200228
PDF is available here.
PDF is available here.
Abstract
We studied their expression and localization in normal subjects and in genetically characterized UCMD and BM patients. We found that localization of α5, and to a lesser extent α6, is restricted to the papillary dermis, where the protein mainly colocalizes with collagen fibrils. In addition, both c...
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PMID: 20882040
PDF is available here.
PDF is available here.
Clinical calcium (20)11 2010
Abstract
The cohort studies reported the subclinical vascular calcification including atheroslerosis starts during prediabetic state characterized by impaired fasting glucose. In the cardiovascular systems of diabetes mellitus there is an original mechanism to induce the medial calcification other than intim...
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PMID: 21037381
PDF is available here.
PDF is available here.
Clinical calcium (20)11 2010
Abstract
Atherosclerotic vascular damage associated with aging manifest several features, namely atherosis, sclerosis and calcified change, finally leading to cardiovascular (CV) events. Accumulating recent reports show the importance of cellular senescence in atherosclerogenesis; however, few reports have a...
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PMID: 21037384
PDF is available here.
PDF is available here.
Abstract
We report, based on measurements of dihydroethidium fluorescence, tissue isoprostane, GSH, and ascorbate content, that peripubertal GH/IGF-1 deficiency in Lewis dwarf rats increases vascular oxidative stress, which is prevented by GH replacement. Peripubertal GHD did not alter superoxide dismutase o...
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PMID: 20713653
PDF is available here.
PDF is available here.
Abstract
Abstract
A thorough understanding of vascular biology will assist the reconstructive surgeon in both operative planning and development of novel surgical approaches to treat chronic wounds and tissue loss, and to optimize regenerative strategies for tissue reconstruction. In this review, several fundamental...
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PMID: 21042110
PDF is available here.
PDF is available here.
Abstract
Perforator flaps have increased in use, with advantages such as sparing of the underlying muscle with resultant decreased donor-site morbidity and the possibility of improving aesthetic outcome. Theoretically, a flap can be based on any perforator, whether free or pedicled, based on the perforasome...
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PMID: 21042115
PDF is available here.
PDF is available here.
Abstract
Various tissue resident stem cells are receiving attention from basic scientists and clinicians as they hold promise for myocardial regeneration. For practical reasons, adipose tissue-derived stem cells (ASCs) are attractive cells for clinical application in repairing damaged myocardium based on the...
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PMID: 20833143
PDF is available here.
PDF is available here.
Oral Diseases (16)7 2010
Abstract
Tooth extraction has been identified as an important risk factor for bisphosphonate-induced osteonecrosis of the jaw. Therefore, the main goal of this study was to determine the effects of alendronate on healing of the extraction socket and on interdental alveolar bone after tooth extraction in rats...
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PMID: 20846154
PDF is available here.
PDF is available here.
Abstract
We report eight homologs of mical family genes in zebrafish and their expression profiles during embryonic development. Consistent with the findings in Drosophila and mammals, most zebrafish mical family genes display expression in neural and musculature systems. In addition, five mical homologs are...
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PMID: 21035094
PDF is available here.
PDF is available here.
Abstract
The molecular regulation of smooth muscle cell (SMC) behavior is reviewed, with particular emphasis on stimuli that promote the contractile phenotype. SMCs can shift reversibly along a continuum from a quiescent, contractile phenotype to a synthetic phenotype, which is characterized...
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PMID: 20334504
PDF is available here.
PDF is available here.
Biomedical Materials (5)5 2010
Abstract
We exploited a polymer blending procedure to heparinize the chitosan material under simple and mild conditions to improve its antithrombogenic property. By an optimized procedure, a macroscopically homogeneous chitosan-heparin (Chi-Hep) blended suspension was obtained, with which Chi-Hep composite f...
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PMID: 20826908
PDF is available here.
PDF is available here.
Biomedical Materials (5)5 2010
Abstract
We investigated whether implantation of vascular bundles or sensory nerves affected the expression of calcitonin gene-related peptide type I receptor (CGRP1R) and neuropeptide Y1 receptor (NPY1R) in tissue-engineered bone. We implanted osteogenically induced bone marrow mesenchymal stem cells (BMSCs...
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PMID: 20826910
PDF is available here.
PDF is available here.
Brain research (1354) 2010
Abstract
The pathophysiology of early ischemic injury after aneurysmal subarachnoid hemorrhage (SAH) is not understood. This study examined the acute effect of endovascular puncture-induced SAH on parenchymal vessel function in rat, using intravascular fluorescent tracers to assess flow and vascular permeabi...
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PMID: 20654597
PDF is available here.
PDF is available here.
Abstract
In this Commentary, the roles of uridine adenosine tetraphosphate as an endothelium-derived contracting or relaxing factor described in the paper by Tölle et al. are considered and put into the wider context of the mechanisms of control of vascular tone by purinergic signalling via receptors loca...
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PMID: 20880393
PDF is available here.
PDF is available here.
Abstract
Our data suggest that, notwithstanding the large analytical variability found, multiple proteomic profiles obtained from each subject can differentiate cirrhosis with and without HCC, and HCCs with and without vascular invasion, warranting further investigation in a prospective setting....
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PMID: 20509833
PDF is available here.
PDF is available here.
Acta Biomaterialia (6)9 2010
Abstract
We developed an extracellular microenvironment by modifying fibrinogen with various polyethylene glycol (PEG) derivatives. We hypothesized that adjusting the type of PEG derivative to modify the resultant physical and mechanical characteristics of fibrin would allow us to create a tunable system for...
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PMID: 20302976
PDF is available here.
PDF is available here.
Abstract
A series of 5-(3',4',5'-trimethoxyphenyl)pyrrolo[3,4-a]carbazole-1,3(2H,10H)-diones was designed as cis-restricted analogues of 3-aroylindoles, arylthioindoles and 3-benzylidoneindolin-2-ones derived from combretastatin A4 (CA-4). Starting from various indoles, compounds were synthesized by means of...
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PMID: 20538383
PDF is available here.
PDF is available here.
Orvosi Hetilap (151)35 2010
Abstract
Journal of Hypertension (28)9 2010
Abstract
We re-examined earlier data in Page hypertension.
Total peripheral resistance (TPR) and total peripheral conductance (TPC) responsiveness were compared in hypertensive and normotensive rabbits, 5 weeks after bilateral renal cellophane wrapping or sham operation. The rabbits were studied with effecto...
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PMID: 20543714
PDF is available here.
PDF is available here.
Abstract
The amount of fluid administered was not significantly different between the groups. Two patients in group 1, 13 patients in group 2 and 12 patients in group 3 were treated with dobutamine (P < 0.001). None of the patients anaesthetized with sevoflurane (groups 1 and 2) experienced postoperative car...
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PMID: 20613538
PDF is available here.
PDF is available here.
Kardiologia polska (68)9 2010
Abstract
Remodelling process is associated with activity of such substances as transforming growth factor β1 (TGFβ1), basic fibroblast growth factor (bFGF, FGF2), or insulin like growth factor-1 (IGF-1). In the course of hypertension the remodelling of blood vessels and heart muscle takes place. Studies pe...
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PMID: 20859888
PDF is available here.
PDF is available here.
Kardiologia polska (68)9 2010
Abstract
Anesthesia & Analgesia (111)3 2010
Abstract
Ultrasound-guided interscalene and supraclavicular blocks are effective and safe for shoulder arthroscopy. Temporary and permanent PONS is uncommon....
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PMID: 20686013
PDF is available here.
PDF is available here.
Thrombosis and Haemostasis (104)3 2010
Abstract
Thrombosis and Haemostasis (104)3 2010
Abstract
Elevated serum phosphate is a risk factor for vascular calcification and cardiovascular events in kidney disease as well as in the general population. Elevated phosphate levels drive vascular calcification, in part, by regulating vascular smooth muscle cell (VSMC) gene expression, function, and fate....
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PMID: 20664908
PDF is available here.
PDF is available here.
Thrombosis and Haemostasis (104)3 2010
Abstract
Neovascularisation is crucial both for physiological processes, like development, wound healing, tissue regeneration, hair growth or menstrual cycle, and for pathological states, such as tumour progression, retinopathy and psoriasis. Blood vessel formation is orchestrated by numerous pro-angiogenic...
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PMID: 20539916
PDF is available here.
PDF is available here.
Abstract
We report effects of TCDD exposure on the morphology of some blood vessels in the head of developing zebrafish. TCDD caused concentration-dependent anatomical rearrangements in the shape of the prosencephalic artery in zebrafish larvae. In contrast, no major vascular defects were recognized in the t...
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PMID: 20554057
PDF is available here.
PDF is available here.
Developmental Biology (344)2 2010
Abstract
Tightly regulated crosstalk between endothelial cells and pericytes is required for formation and maintenance of functional blood vessels. When the NG2 proteoglycan is absent from pericyte surfaces, vascularization of syngeneic tumors growing in the C57Bl/6 mouse brain is aberrant in several respect...
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PMID: 20599895
PDF is available here.
PDF is available here.
Circulation Journal (74)8 2010
Abstract
Circulation Journal (74)8 2010
Abstract
Matrix metalloproteinases (MMPs) contribute to extracellular remodeling in Kawasaki disease (KD). MMP-9 is an essential vasculature-remodeling factor but its role in the vascular lesions of KD is not understood. This study focused on MMP-9 regulation via cytokines in endothelial cells (ECs).
Plasma...
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PMID: 20534943
PDF is available here.
PDF is available here.
Abstract
Our computational results for alterations in flow and pressure, using reasonable physiological values for rates of constituent growth and turnover, concur with findings in the literature. For example, for flow-induced remodeling, our simulations predict that, although the wall shear stress is restor...
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PMID: 20039091
PDF is available here.
PDF is available here.
Abstract
This review focuses on mechanisms and emerging concepts that drive the science of stroke in a therapeutic direction. Once considered exclusively a disorder of blood vessels, growing evidence has led to the realization that the biological processes underlying stroke are driven by the...
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PMID: 20670828
PDF is available here.
PDF is available here.
Abstract
Abstract
Oncotarget (1)4 2010
Abstract
We and others have shown that PDGF-C is a critical player in pathological angiogenesis because of its pleiotropic effects on multiple cellular targets. The angiogenic pathways induced by PDGF-C are, to a large extent, VEGF-independent. These pathways may include, but not limited to, the direct effec...
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PMID: 20871734
PDF is available here.
PDF is available here.
Abstract
Folia morphologica (69)3 2010
Abstract
This study introduces an anatomical basis for surgeries such as thoracoscope-assisted thoracolumbar spinal anterior interbody fusion in terms of image observing and corpse specimen anatomising. The observation of the 3-dimensional computed tomography (CT) image indicates that segmental arteries are...
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PMID: 21154281
PDF is available here.
PDF is available here.
Urological Research (38)4 2010
Abstract
Our results suggest that all three mechanisms, vessel distention, invagination and liquid jets, can contribute to vessel rupture....
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PMID: 20680255
PDF is available here.
PDF is available here.