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Anesthetics (3):
Recent article
Anesthetics
Abstract
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Anesthesiology (114)1 2011
Abstract
Anesthesiology (114)1 2011
Abstract
We collected data of inpatients who had general anesthesia between July and December 2006-2008. Patients' age, gender, diagnoses, procedures, and the use of drugs during anesthesia, including volatile agents, muscle relaxants, and propofol, were investigated. Univariate comparisons were made to exam...
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PMID: 21169796
PDF is available here.
PDF is available here.
Anesthesiology (113)6 2010
Abstract
Abstract
Maternal complications related to anesthesia are low in comparison with the results from obstetric factors in developing countries. The purposes of the present study were to determine the incidence of maternal mortality related to anesthesia, to analyze the causes and to suggest measures to improve...
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PMID: 21114206
PDF is available here.
PDF is available here.
Progress in Brain Research (170)170 2029
Abstract
Vasopressin (VP) secreted from parvocellular neurons of the hypothalamic paraventricular nucleus (PVN) stimulates pituitary adrenocorticotropic hormone (ACTH) secretion, through interaction with receptors of the V1b subtype (V1bR) in the pituitary corticotroph, mainly by potentiating the stimulatory...
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PMID: 18655869
PDF is available here.
PDF is available here.
Abstract
Abstract
We consider substrate-related compounds, intermediates or products of the Luc catalyzed reactions, in addition to anesthetics and, fatty acids. This review summarizes the main inhibitors of Luc and the corresponding inhibition kinetic parameters.
Copyright 2010 Elsevier B.V. All rights reserved....
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PMID: 20655239
PDF is available here.
PDF is available here.
Dermatologic Clinics (28)4 2010
Abstract
Vulvar pruritus is a common and distressing condition for patients, and its presentation is often delayed and complicated by home remedies. The true prevalence cannot be accurately estimated. Vulvar pruritus is a symptom, and an underlying cause must be sought and not assumed. This is best accomplis...
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PMID: 20883911
PDF is available here.
PDF is available here.
Anesthesiology (113)4 2010
Abstract
Anesthesiology (113)4 2010
Abstract
Abstract
The chromatographic evaluation divided the tested drugs into more hydrophobic ones containing nonselective beta-blockers and less hydrophobic ones containing selective beta1-blockers. Nonselective beta-blockers, but not selective beta1-blockers, fluidized liposomal membranes, with the potency being...
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PMID: 20601889
PDF is available here.
PDF is available here.
Abstract
The amount of fluid administered was not significantly different between the groups. Two patients in group 1, 13 patients in group 2 and 12 patients in group 3 were treated with dobutamine (P < 0.001). None of the patients anaesthetized with sevoflurane (groups 1 and 2) experienced postoperative car...
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PMID: 20613538
PDF is available here.
PDF is available here.
Abstract
Sixty patients completed the study, 30 in each group. VAS scores at 8 h were significantly higher in the H-BIS group, both at rest [1 (0-4) vs. 2 (0-8), P = 0.036] and on cough [1 (0-5) vs. 2 (2-9), P = 0.021], but at 24 h were similar between the two groups. Four patients in the L-BIS group and 17...
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PMID: 20679774
PDF is available here.
PDF is available here.
Abstract
Abstract
Mean +/- SD interval to achieve stage 2 anesthesia with isoeugenol ranged from 22.4 +/- 6.2 minutes at 20 mg/L to 0.25 +/- 0.4 minutes at 500 mg/L, whereas the mean interval to stage 3 anesthesia ranged from 28.1 +/- 3.9 minutes at 20 mg/L to 0.33 +/- 0.48 minutes at 500 mg/L. With the exception of...
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PMID: 20673083
PDF is available here.
PDF is available here.
Abstract
Abstract
POCD has emerged as a new concern for anesthesiologists and their older patients. Several recent studies indicate that POCD is common after noncardiac surgery, with an incidence approaching 30-40% at discharge, although this incidence declines at 3 months. Some data suggest that POCD imparts risk fo...
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PMID: 20489604
PDF is available here.
PDF is available here.
Abstract
A morbidly obese individual's increased cardiac output requires administration of higher drug doses than would be required for a standard-size person to attain the same peak-plasma concentration. Lean body weight (LBW) is highly correlated with the increased cardiac output, more so than fat mass or...
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PMID: 20531173
PDF is available here.
PDF is available here.
Abstract
Anesthesia in prehospital emergencies and in the emergency department is reviewed and guidelines are discussed. SUMMARY: Preoxygenation should be performed with high-flow oxygen delivered through a tight-fitting face mask with a reservoir. Ketamine may be the induction agent of choice in hemodynamic...
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PMID: 20543679
PDF is available here.
PDF is available here.
Abstract
Anesthesia outside of the operating room is rapidly increasing in numbers, which has seen a growth of older and sicker patients. These circumstances have created a need for guidelines, for both specialist anesthesia providers and nonanesthesia-trained practitioners, that define patient selection, mi...
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PMID: 20585246
PDF is available here.
PDF is available here.
Abstract
We review the emergency department evaluation of the airway in obesity, discussing anatomy, physiology, and pharmacology. In addition, we describe techniques and devices used to improve intubating conditions in the obese patient. After our review of the relevant literature, we conclude that research...
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PMID: 20363528
PDF is available here.
PDF is available here.
NeuroImage (51)4 2010
Abstract
To date, the majority of neurovascular coupling studies focused on the thalamic afferents' activity in layer IV and the corresponding large spiking activity as responsible for functional hyperemia. This paper highlights the role of the secondary and late cortico-cortical transmission in neurovascula...
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PMID: 20350606
PDF is available here.
PDF is available here.
Abstract
Abstract
Anesthesiology (113)1 2010
Abstract
Anesthesiology (113)1 2010
Abstract
In patients undergoing cardiopulmonary bypass, we found no overall association between BIS and Svo2. A weak but statistically significant association between BIS and Svo2 was observed in patients with temperatures less than 34.1 degrees C. These data suggest that low Svo2 values on bypass are unlike...
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PMID: 20508497
PDF is available here.
PDF is available here.
Abstract
Endosulfan is an organochlorine pesticide commonly used in agriculture. Endosulfan has affects on vertebrate xenobiotic metabolism pathways that may be mediated, in part, by its ability to activate the pregnane X receptor (PXR) and/or the constitutive androstane receptor (CAR) which can elevate expr...
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PMID: 20361990
PDF is available here.
PDF is available here.
Abstract
Abstract
There is no integrated pharmacokinetic/pharmacodynamic analysis that can supply parameter estimates to be programmed into pumps for either plasma or effect-site concentration determination over the broad paediatric age range. The six pharmacokinetic parameter sets available for children out of infan...
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PMID: 20386438
PDF is available here.
PDF is available here.
Abstract
New antiepileptic drugs (AEDs) have been a major change in the approach to management of patients with epilepsy. These drugs tend to have fewer significant drug interactions and less severe side effects. Nonetheless, first-generation AEDs are still widely used. Propofol and desflurane have reliable...
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PMID: 20421790
PDF is available here.
PDF is available here.
Abstract
Among 407 incident reports and 559 incidents, there were more male (52.8%) than female (46.7%) patients with ASA PS 2, 3, 4 and 5 = 38.6%, 42.8%, 14.5% and 4.2% respectively. Surgical specialties that posed high risk of incidents were general, orthopedic, neurological, urologic and otorhiolaryngolog...
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PMID: 20572375
PDF is available here.
PDF is available here.
AANA Journal (78)3 2010
Abstract
Apoptosis, or programmed cell death, is a physiologic mechanism employed by most multicellular organisms to maintain homeostasis of body tissues. In balance with the production of new cells by mitosis, apoptosis provides for the orderly destruction and removal of cells that are no longer needed by t...
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PMID: 20572411
PDF is available here.
PDF is available here.
Abstract
Abstract
Knowledge of biological rhythms has led to better understanding of the time-of-day dependent effects of anaesthetic drugs. These chronopharmacological effects are currently explained by the biological rhythms modulating the pharmacokinetic, toxic and pharmacodynamic parameters of these substances. S...
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PMID: 20598847
PDF is available here.
PDF is available here.
Abstract
To expose the current knowledge about the anaesthetic effects on the developing brain.
Publications (original articles and reviews) in English and in French language from 1980 were obtained from the Medline database using alone or in combination following keywords: anaesthetics, developing brain, ne...
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PMID: 20537849
PDF is available here.
PDF is available here.
Anesthesiology (112)6 2010
Abstract
Abstract
The increase in the use of magnetic resonance imaging (MRI) for diagnostic use in companion animals has increased the demand for anesthesia support in a strong magnetic environment. In many instances, this may necessitate anesthesia being provided by individuals that are unfamiliar w...
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PMID: 20515673
PDF is available here.
PDF is available here.
Abstract
We modelled the financial and environmental costs of two commonly used anaesthetic plastic drug trays. We proposed that, compared with single-use trays, reusable trays are less expensive, consume less water and produce less carbon dioxide, and that routinely adding cotton and paper increases financi...
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PMID: 20514965
PDF is available here.
PDF is available here.
Abstract
A final standardized medication drawer (content and positioning) was developed over 30 months, with agreement from anesthesiologists (n = 12) and anesthesia assistants (n = 3) at the three hospitals. Guidelines for placing each medication in the drawer included grouping them according to order of us...
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PMID: 20143279
PDF is available here.
PDF is available here.
Zhonghua Yixue Zazhi (90)17 2010
Abstract
Such minimally invasive surgery has little effect on the circulation. The difficulty of anesthetic management is smaller. Specific anticoagulation management is administered. Implementation of the Fast-track technology can demonstrate the further advantages in such surgery....
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PMID: 20646564
PDF is available here.
PDF is available here.
Anesthesiology (112)5 2010
Abstract
Anesthesiology (112)5 2010
Abstract
Abstract
Critically ill patients are at an increased risk to develop drug-drug interactions (DDIs). DDIs that increase the risk of QT prolongation, and ultimately torsades de pointes, can result in a medical emergency. Many clinicians are unaware of the risk of certain drug combinations that may precipitate...
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PMID: 20377471
PDF is available here.
PDF is available here.
Abstract
Modern computer-based methods to monitor anesthesia are widespread. They are used in order to avoid awareness, to reduce consumption of anesthetics, to optimize recovery times and to detect prolonged times of deep anesthesia and associated immunsuppression, mortality and morbidity. This review illus...
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PMID: 20387178
PDF is available here.
PDF is available here.
Abstract
In this 10-year period, 23 cases of iatrogenic colonic perforation were recorded (0.065%) affecting 11 men and 12 women. The mean age was 71.2 years. There were 13 patients in American Society of Anesthesiology (ASA) classifications 1 or 2 (low anesthetic risk, group A), and ten patients in ASA clas...
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PMID: 19855987
PDF is available here.
PDF is available here.
Abstract
Antiinflammatory (antiexudative, antiproliferative) activity of calcium pectate was revealed by tests on the mice leg carrageenan-induced edema and cotton-ball granuloma models. It was also established that this polysaccharide produced an anesthetic effect comparable with that of indomethacin on the...
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PMID: 20486555
PDF is available here.
PDF is available here.
Abstract
The risk of death associated with anaesthesia is closely related to patient age and physical status. In otherwise healthy patients (ASA 1), the risk of such deaths is approximately 1:250 000. Medication errors occur in approximately 1:1 000 anaesthetic procedures. The risk of awareness during genera...
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PMID: 20224619
PDF is available here.
PDF is available here.
Abstract
When selecting anaesthetic approach and anaesthetic drugs one has to consider not only the perioperative period, but also postoperative aspects such as pain relief, awakeness, functional ability and absence of nausea. After major surgery, regional anaesthesia (especially epidural anaesthesia) and po...
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PMID: 20220866
PDF is available here.
PDF is available here.
Abstract
Day case surgery is becoming more and more important. In order to perform these services cost-efficiently it is of primary importance to ensure that procedures can be scheduled with the largest possible patient satisfaction. Up to now spinal anaesthesia was of little importance in day case surgery d...
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PMID: 20232274
PDF is available here.
PDF is available here.
Abstract
The case of an 8 year-old boy undergoing resection of pheochromocytoma, who received a combination of dexmedetomidine and magnesium sulfate (MgSO4) for hemodynamic control, is reported. He was prepared for surgery with phenoxybenzamine and atenolol. Dexmedetomidine was started in the preoperative ho...
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PMID: 20304355
PDF is available here.
PDF is available here.
Abstract
We present the maternal and fetal considerations in anesthesia for intracranial hemorrhage....
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PMID: 20229751
PDF is available here.
PDF is available here.
Anesthesiology (112)3 2010
Abstract
Anesthesiology (112)3 2010
Abstract
Anesthesiology (112)3 2010
Abstract
Endothelial nitric oxide synthase activity is regulated by (6R-)5,6,7,8-tetrahydrobiopterin (BH4) and heat shock protein 90. The authors tested the hypothesis that hyperglycemia abolishes anesthetic preconditioning (APC) through BH4- and heat shock protein 90-dependent pathways.
Myocardial infarct s...
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PMID: 20124983
PDF is available here.
PDF is available here.
Journal of Anesthesia (24)1 2010
Abstract
According to the guidelines of the American College of Cardiology/American Heart Association 2006 for perioperative cardiovascular evaluation for non-cardiac surgery, beta-blocker therapy should be considered for high-risk individuals undergoing vascular surgery or high- and intermediate-risk patien...
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PMID: 20175288
PDF is available here.
PDF is available here.
Abstract
A total of 104 patients' records were read and 80 anesthesiologists were surveyed. We found that 31 (29.8%) patients received N2O during anesthesia. The survey showed that 62 (77.5%) of the anesthesiologists had used N2O in the last 6 months. Nine (50%) of the anesthesiologists who had not used N2O...
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PMID: 20336997
PDF is available here.
PDF is available here.
Abstract
General anesthesia was given twice to a 9-year-old girl with Lennox-Gastaut syndrome (LGS). LGS is one of the catastrophic forms of childhood epilepsy, and very few reports describe its anesthetic management. The anesthetic concern in LGS patients is a possibility of perioperative epilepsy due to pr...
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PMID: 20169970
PDF is available here.
PDF is available here.
Critical Care (14)2 2010
Abstract
In the previous issue of Critical Care, Meybohm and colleagues provide evidence to support hypothermia as a kind of therapeutic option for patients suffering cardiac arrest. Although anesthetics had been used to induce hypothermia, sevoflurane post-conditioning fails to confer additional anti-inflam...
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PMID: 20398330
PDF is available here.
PDF is available here.
Abstract