Abstract
To compare outcomes among neonates delivered after documentation of fetal lung maturity before 39 weeks and those delivered at 39 or 40 weeks.
This was a retrospective cohort study of women with singleton pregnancy delivered at 36 0/7 to 38 6/7 weeks after positive fetal lung maturity testing (based...
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PMID: 21099593
PDF is available here.
Abstract
Despite substantial progress in prevention of perinatal group B streptococcal (GBS) disease since the 1990s, GBS remains the leading cause of early-onset neonatal sepsis in the United States. In 1996, CDC, in collaboration with relevant professional societies, published guidelines for the prevention...
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PMID: 21088663
PDF is available here.
Abstract
We investigated the prevalence of neonatal deaths in the special care baby unit (SCBU) at the main children's hospital in Tripoli and the factors associated with these deaths. We reviewed the medical records of all neonates who died in our SCBU from 1 January 2003 to 31 December 2005. A total of 117...
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PMID: 21218737
PDF is available here.
Abstract
We compared 15,136 gestations born late preterm with 170,593 deliveries between 37 0/7 and 41 6/7 weeks. We defined the following categories of precursors for late preterm delivery: "spontaneous labor," "premature rupture of the membranes (preterm PROM)," "indicated" delivery, and "unknown." Inciden...
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PMID: 20966688
PDF is available here.
Abstract
We report a series of cases of thyroid dysfunction in adults associated with ingestion of a brand of soy milk manufactured with kombu (seaweed), and a case of hypothyroidism in a neonate whose mother had been drinking this milk. We also report two cases of neonatal hypothyroidism linked to maternal...
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PMID: 20919974
PDF is available here.
Abstract
To determine the predictors of mortality in neonatal septicemia.
The records of babies with culture-proven septicemia managed in a Nigerian newborn unit between 2006 and 2008 were studied using bivariate and multivariate analysis.
Out of 174 babies with septicemia, 56 (32.2%) died. Outborn babies, b...
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PMID: 21053706
PDF is available here.
Abstract
We examined listeriosis cases reported through the U.S. Listeria Initiative during 2004-2007. Cases were classified as pregnancy-associated if illness occurred in a pregnant woman or an infant aged <28 days. Of 758 reported Listeria cases, 128 (16.9%) were pregnancy-associated. Maternal infection re...
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PMID: 20158931
PDF is available here.
Abstract
About 5000 babies annually, or 1/12 of all births, are the result of vacuum-assisted delivery in Denmark. Towards the end of the 1990'ies, the US FDA published a national warning concerning increasing complications and mortality after vacuum-assisted delivery, and other countries followed. One expla...
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PMID: 20825742
PDF is available here.
Abstract
We studied all infants with birth weights between 500 g and 1500 g who were admitted to 6 neonatal intensive care units of the Brazilian Network on Neonatal Research for 2 years. Exclusion criteria were major malformations, death in the delivery room, and maternal chronic hypertension. Absolute neut...
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PMID: 20400101
PDF is available here.
Abstract
We evaluated the effect of IaIp on survival and systemic responses to sepsis in neonatal mice. Sepsis was induced in 2-d-old mice with lipopolysaccharide (LPS), Escherichia coli, and group B Streptococci. Sepsis was associated with 75% mortality. IaIp, given by i.p. administration at doses between 1...
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PMID: 20520583
PDF is available here.
Abstract
We report definitive diagnosis and effective chenodeoxycholic acid (CDCA) treatment of two Japanese children with 3[beta]-hydroxy-[DELTA]5-C27-steroid dehydrogenase/isomerase deficiency. Findings of cholestasis with normal serum [gamma]-glutamyltransferase activity and total bile acid concentration...
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PMID: 20531254
PDF is available here.
Jerrie S Refuerzo,
Valerija Momirova,
Alan M Peaceman,
Anthony Sciscione,
Dwight J Rouse,
Steve N Caritis,
Catherine Y Spong,
Michael W Varner,
Fergal D Malone,
Jay D Iams,
Brian M Mercer,
John M Thorp,
Yoram Sorokin,
Marshall W Carpenter,
Julie Lo,
Margaret Harper and
Eunice Kennedy Shriver National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network
Abstract
We compared neonatal outcomes in twin pregnancies following moderately preterm birth (MPTB), late preterm birth (LPTB), and term birth. A secondary analysis of a multicenter, randomized controlled trial of multiple gestations was conducted. MPTB was defined as delivery between 32 (0)/(7) and 33 (6)/...
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PMID: 20175042
PDF is available here.
Abstract
Demographic, labor characteristics, and neonatal outcomes of the two groups were comparable. The onset of analgesia was relatively more rapid for ropivacaine group (p = 0.067). Duration of analgesia after the first bolus dose was longer and the need for supplemental epidural analgesic doses was less...
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PMID: 20583937
PDF is available here.
Abstract
Compared to all other obese and non-obese women, super-obese women had the highest rates of preeclampsia, GDM, LGA, and cesarean delivery (all p < 0.05 for trend test). Super-obesity was also associated with a 44% reduction in SGA compared to all other women (OR 0.55, 95% confidence interval (CI) 0....
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PMID: 20438391
PDF is available here.
Abstract
We report three unrelated Malay children with genetically confirmed NICCD characterised by an insertion mutation IVS16ins3kb in SLC25A13 gene. All 3 patients presented with prolonged neonatal jaundice which resolved without specific treatment between 5 to 10 months. Of note was the manifestation of...
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PMID: 20614727
PDF is available here.
Abstract
Metabolomics is a new approach based on the systematic study of the full complement of metabolites in a biological sample. This technology consists of two sequential steps: (1) an experimental technique, based on mass spectrometry or nuclear magnetic resonance (NMR) spectroscopy, designed to profile...
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PMID: 21089734
PDF is available here.
Abstract
The field of neonatology presents a fascinating context in which hugely important decisions have to be made on the basis of physicians' assessments of the long term consequences of various possible choices. In many cases such assessments cannot be derived from a consensual professional opinion; the...
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PMID: 21089732
PDF is available here.
Abstract
Hypoxia-ischemia (H-I) constitutes the main phenomenon responsible for brain-blood barrier permeability modifications leading to cerebral vascular autoregulation loss in newborns. Hypotension, cerebral ischemia, and reperfusion are the main events involved in vascular auto-regulation loss leading to...
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PMID: 21090084
PDF is available here.
Abstract
With increased survival of extremely low birth weigh (ELBW) and very ill infants, a lot of them are discharged with unresolved medical issues that complicate their subsequent care. Infants born preterm with low birth weight who require neonatal intensive care experience a much higher rate of hospita...
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PMID: 21090070
PDF is available here.
Abstract
Macrosomic infants (birth weight >4000 g) show increased risk for shoulder dystocia and associated injuries, hypoglycemia and respiratory distress. Higher risk is directly related to neonatal birth weight. High birth weight is also associated with increased risk of developing metabolic syndrome late...
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PMID: 21090075
PDF is available here.
Sarah Saleem,
Dwight J Rouse,
Elizabeth M McClure,
Anita Zaidi,
Tahira Reza,
Y Yahya,
I A Memon,
N H Khan,
G Memon,
N Soomro,
Omrana Pasha,
Linda L Wright,
Janet Moore and
Robert L Goldenberg
Abstract
From 2005 to 2008, 5,008 laboring women and their neonates were randomly assigned to receive either chlorhexidine wipes (n=2,505) or wipes with a saline placebo (n=2,503). The primary outcome was similar in the chlorhexidine and control groups (3.1% compared with 3.4%; relative risk 0.91, 95% confid...
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PMID: 20502294
PDF is available here.
Abstract
There were 34 pregnancies and deliveries complicated by HELLP syndrom between the years 2004 and 2009 (64 months). The average age of mothers was 28.5 years, the average gestational age at delivery time was 33 weeks and 4 days. Only 2 women delivered vaginaly, the other 32 delivered by cesarean sect...
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PMID: 20731305
PDF is available here.
Abstract
Three hundred-forty-eight out of a regional population of 1272 newborn infants were randomly chosen and followed neurologically until age of two years to study the epidemiology of neurodevelopmental disorders, and to reveal the main factors influencing outcome. The most frequent neonatal pathologies...
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PMID: 19683948
PDF is available here.
Abstract
A 6-week-old girl, the first child of non-consanguineous parents, was admitted to the hospital for evaluation of vomiting. She was small for gestational age (1500 g). On admission, she weighed 1830 g, and appeared dehydrated. The blood glucose was 880 mg/dL. Insulin and C-peptide levels were <1 micr...
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PMID: 20662354
PDF is available here.
Abstract
We examined whether the incidence of neonatal respiratory disorders has increased with the increased rate of elective cesarean delivery in twin pregnancies. We reviewed the obstetric records of 292 twin deliveries with vertex presentation of the first twin after 37 weeks' gestation at our hospital f...
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PMID: 20453421
PDF is available here.
Abstract
OBJECTIVE: To determine whether planned route of delivery leads to differences in neonatal morbidity. STUDY DESIGN: Analysis was based on planned route of delivery, not actual route of delivery. A total of 4048 subjects were divided into two groups: planned vaginal delivery and planned cesarean deli...
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PMID: 19812591
PDF is available here.
Abstract
We investigated the relationship between illness severity and accuracy of neonatal sepsis screen. Consecutive neonates with clinically suspected early onset sepsis (EOS) were enrolled and blood culture and sepsis screen [C-reactive protein, absolute neutrophil count, immature to total ratio (ITR) an...
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PMID: 20013577
PDF is available here.
Abstract
We performed 2-dimensional difference gel electrophoresis, statistical analysis, and tandem mass spectrometry using serum samples from 19 infants with BA and 19 infants with non-BA neonatal cholestasis.
Eleven potential serum biomarkers were found that could in combination classify children with neo...
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PMID: 20216099
PDF is available here.
Abstract
We present an observational study of 55 premature infants born weighing less than 1.3 kg within two level III neonatal intensive care units. Endotracheal aspirates (ETA) and nasogastric aspirates (NGA) were studied with denaturing gradient gel electrophoresis (DGGE) profiling to elucidate the total...
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PMID: 20035248
PDF is available here.
Abstract
An evaluation of infant morbimortality and mother morbidity was undertaken according to the type of delivery. A prospective study was undertaken on 170 puerperal patients divided into two groups: Group 1 (n = 95), natural or vaginal delivery, Group 2 (n = 75), submitted to caesarean delivery. Compli...
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PMID: 20414611
PDF is available here.
Abstract
Gestational diabetes mellitus (GDM) is a type of diabetes that presents during pregnancy and usually disappears shortly after a woman gives birth. Better recognition of the risk factors of GDM, combined with more universal screening for the disease in many countries, has led to the increased detecti...
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PMID: 20121460
PDF is available here.
Abstract
We report herein the case of a newborn baby with critical PVS with inferior vena cava interruption, severe tricuspid regurgitation and a severely enlarged right atrium. We tried BPV through the transumbilical approach with difficulty, but he was successfully treated with the assistance of a coronary...
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PMID: 20191053
PDF is available here.
Abstract
When maternal APS features and variables of infant outcome were analyzed, it was evident that lupus anticoagulant (LAC), triple antiphospholipid positivity, and history of vascular thrombosis were significantly associated with some parameters of a poor infant outcome. History of pregnancy morbidity...
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PMID: 20391475
PDF is available here.
Abstract
Neonatal-Perinatal Medicine has had both its triumphs and its disasters regarding the dissemination of new interventions. Evidence-based medicine (EBM), the integration of clinical expertise, patient values, and best evidence for decision making in patient care, provides a blueprint for how to safel...
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PMID: 20363445
PDF is available here.
Abstract
Neonatal cytomegalovirus (CMV) infection is common, has myriad presentations and severe sequelae. Six neonates clinically suspected of CMV infection were confirmed by qualitative PCR (Digene) and evaluated. Those with persistent viremia were treated with Ganciclovir intravenously for 4-6 weeks, and...
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PMID: 19430062
PDF is available here.
Abstract
In spite of not being currently recommended, intrapartum suction and postnatal intubation and suction of vigorous infants with MSAF are commonly performed in Argentina while in depressed newborns the latter procedure is not always carried out. Our study confirms the frequent gaps observed between sc...
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PMID: 20204237
PDF is available here.
Abstract
Low risk CD at term was associated with a higher neonatal morbidity, NICU admission and maternal pain in the puerperium. It also reduces exclusive breastfeeding rate at discharge....
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PMID: 20204235
PDF is available here.
Abstract
Haemosiderosis in the placenta is not an artefact of placental handling. Haemosiderosis is seen considerably more frequently than previously reported and may be physiological. Haemosiderosis is not a useful indicator for chronic placental abruption and adverse neonatal outcome is not significantly c...
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PMID: 20085512
PDF is available here.
Abstract
Perinatal and infant mortality are two major contributors to child mortality in developing world. It is widely recognised that synergistic efforts by paediatric and obstetric healthcare providers result in improvement of neonatal and infant survival. Close working relationship betwee...
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PMID: 21409928
PDF is available here.
Abstract
We report an asymptomatic mother of a cutaneous neonatal lupus child was diagnosed with Sjögren's syndrome suspected after parturition. A 30-year old woman was visited our hospital to evaluated autoimmune disease because her baby was diagnosed as cutaneous neonatal lupus. Both gum test and Schirmer...
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PMID: 20601836
PDF is available here.
Abstract
Presence of delivery complications was related to tic severity and prenatal smoking exposure to severity of comorbid ADHD symptoms. The relationship between smoking exposure in utero and ADHD symptom severity appeared to be more pronounced in children with a positive family history of mental disorde...
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PMID: 20110829
PDF is available here.
Abstract
CMV-IgM and IgG antibodies assessment was not a potential discriminative test to identify congenitally infected newborns. In addition, low birth weight and small head circumference at birth failed to predict congenital CMV infection. CMV-DNA detection in umbilical cord blood at the time of delivery...
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PMID: 20130378
PDF is available here.
Abstract
During that period, a total of 296 (13.17%) blood samples were found to be positive for bacterial isolates. Gram-negative septicemia (80.40%) was identified in more cases than Gram-positive septicemia (20.60%) with Klebsiella species 84 (28.3%) being the most common isolate. Maximum resistance among...
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PMID: 20130381
PDF is available here.
Abstract
The study was designed to evaluate activity of the blood nitric oxide (NO) system in newborns at high risk of perinatal pathology. The observed rise in NO production should be regarded as a compensatory and adaptive reaction facilitating the maintenance of microcirculation and hemodynamics in organs...
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PMID: 20422756
PDF is available here.
Abstract
We examined the effect of body mass index in early pregnancy on pregnancy outcome since no study in Saudi Arabia has addressed this question.
This prospective cohort study involved women registered for antenatal care during the first month of pregnancy at primary health care centers in Al-Hassa, Sau...
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PMID: 20697173
PDF is available here.
Abstract
A short interpregnancy interval less than or equal to six months is not a risk factor for adverse obstetrical and perinatal outcome....
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PMID: 20931802
PDF is available here.
Abstract
The paper describes a rare case of hereditary thesaurismosis, galactosemia, in a full-term neonate girl aged 12 days with morphologically verified fetal giant-cell cholestatic hepatitis with the development of ascitis and jaundice.
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PMID: 20369586
PDF is available here.
Abstract
The paper gives the results of a histological study of 21 liver biopsy specimens from babies of the first year of life, who had clinical manifestations of neonatal hepatitis with cholestasis syndrome. The major morphological variants of hepatic lesion, such as giant-cell hepatitis, chronic active he...
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PMID: 20369579
PDF is available here.
Abstract
Maternal smoking during pregnancy was the most prevalent risk factor, affecting 20% of mothers by self-report, with the figure being possibly twice as high once corrected for under-reporting. Smoking (ORs 1.2), alcohol consumption (ORs 1.2-1.5) and drug dependence (ORs 1.7-2) by the mother during pr...
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PMID: 20524381
PDF is available here.
Abstract
Most of deliveries were vaginal without obstetric intervention (86.6%). The number of deliveries finished with vacuum extractor (4.6%) was statistically significantly bigger in the group with epidural anaesthesia than in the control group. Most of the newborns in the first group were born on time (9...
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PMID: 20499499
PDF is available here.
Abstract
We destroy harmful insects. The most frequent insecticides which are used today are organophosphorus pesticides. This group of compounds make substances whose activity mechanism is based on the inhibition of acetylcholinesterase in nerve synapsis, thus producing holynergic syndrome, resulting from t...
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PMID: 21186557
PDF is available here.
Abstract
Abstract Of diverse growth factors that contribute to normal lung development, vascular endothelial growth factor (VEGF) plays an especially prominent role in the normal growth and development of the pulmonary circulation in the fetus and newborn. Strong experimental and clinical data support the ro...
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PMID: 20204740
PDF is available here.
Abstract
A neonate presented with non-pitting oedema of both feet and right lower leg, caused by primary non-hereditary congenital lymphedema.
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PMID: 20456778
PDF is available here.