Abstract
Metabolic characteristics of physiological and diabetic pregnancies are discussed. The basic factor of these changes is the increasing insulin resistance throughout pregnancy, which in case of diabetes may result in hyperglycemia with undesirable clinical consequences and complicatio...
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PMID: 21959936
PDF is available here.
Abstract
The 2008 National HIV testing guidelines produced jointly by the British Association of Sexual Health and HIV, British HIV Association and British Infection Society recommend HIV testing for patients attending termination of pregnancy (TOP) services and patients diagnosed with cervical intraepithelia...
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PMID: 21835967
PDF is available here.
Abstract
We identified 433 dippers and 230 subjects with a nocturnal non-dipping pattern. Nocturnal SBP dipping was independently of office SBP associated with decreased PWV (p = 0.008), lower ACR (p = 0.001) and NT-proBNP (p = 0.001) and increased GFR (p<0.001).
We conclude that diurnal BP v...
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PMID: 21546328
PDF is available here.
Abstract
We explore the expected epidemiological impact of this strategy in a small population in which HIV transmission is predominantly confined to men who have sex with men (MSM)....
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PMID: 21851767
PDF is available here.
Abstract
Ignorance of bowel cancer symptoms prevent people taking action. One charity's nurses are informing and supporting patients.
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PMID: 21826868
PDF is available here.
Abstract
To investigate the expression of the soluble form of the resident macrophage marker CD163 (sCD163) and its association with core parameters for disease activity, including radiographic progression in early rheumatoid arthritis (RA).
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PMID: 21813065
PDF is available here.
Philip P Haaf,
Cathrin C Balmelli,
Tobias T Reichlin,
Raphael R Twerenbold,
Miriam M Reiter,
Julia J Meissner,
Nora N Schaub,
Claudia C Stelzig,
Michael M Freese,
Patricia P Paniz,
Christophe C Meune,
Beatrice B Drexler,
Heike H Freidank,
Katrin K Winkler,
Willibald W Hochholzer and
Christian C Mueller
Abstract
We hypothesized that NT-proBNP might be useful in the early diagnosis and risk stratification of patients with suspected acute myocardial infarction....
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PMID: 21787902
PDF is available here.
Abstract
We retrospectively reviewed the records of 16 children treated for spondylodiscitis at our hospital between 2000 and 2007. The mean follow-up was 24 months (12 to 38). There was a mean delay in diagnosis in hospital of 25 days in the ten children aged less than 24 months. At presentation only five o...
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PMID: 21768640
PDF is available here.
Abstract
Bipolar disorder often exists for 10 or more years without being correctly diagnosed or treated. Early-onset bipolar disorder is associated with longer treatment delay and a worse outcome than adult-onset bipolar disorder. This activity describes various risk factors for the development of bipolar di...
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PMID: 21824451
PDF is available here.
Abstract
Various early arthritis clinics have provided extensive data on presentation, disease course and outcomes of early inflammatory arthritis (EIA). The present Review summarizes the epidemiological data from these early arthritis cohorts (EACs), which provide information about the frequ...
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PMID: 21670767
PDF is available here.
Abstract
Fungal infections of the orbit represent a small minority of orbital infections. However, due to the virulent nature of some of the fungal species, they can have a devastating effect on ocular functions. Most of these fungi are saprophytes, which cause opportunistic infections. Asper...
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PMID: 21695805
PDF is available here.
Abstract
Drug-induced hepatotoxicity: clinical and biochemical features of 26 patients and a review of the literature. Drug-induced hepatotoxicity is a major cause of iatrogenic diseases. More than 1200 compounds are involved and can reproduce the full range of hepatic disorders. Clinical and biochemical feat...
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PMID: 21779107
PDF is available here.
Abstract
The development and evaluation of early preventative interventions for individuals exposed to a potentially traumatic event (PTE) have been increasing in number and sophistication over the last decade. Evaluation of early interventions for individuals who are symptomatic several weeks after exposure...
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PMID: 21654600
PDF is available here.
Abstract
We compared maturational and degenerative changes of the cellular organizations in rat and human cartilage specimens....
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PMID: 21630246
PDF is available here.
Abstract
ST elevation myocardial infarction (STEMI) is related to acute occlusion of a coronary artery by a fibrin reach thrombus. Early reperfusion may reduce infarct size and improve prognosis. Percutaneous coronary intervention (PCI) is more effective than intravenous fibrinolysis (IVF). Fibrinolysis remai...
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PMID: 21570245
PDF is available here.
Abstract
We have used new techniques to enable structure at depth, using Optical Coherence Tomography, to be imaged in high resolution. Other advances, using Raman spectroscopy, enable the early endoscopic detection of biochemical and molecular changes in tissue that precede any changes in morphology, thus e...
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PMID: 21550515
PDF is available here.
Abstract
The new imaging technology made available today allows for an early detection of small subclinical breast lesions which frequently call for guided presurgical micro-histology.
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PMID: 21565889
PDF is available here.
Philip Haaf,
Tobias Reichlin,
Nils Corson,
Raphael Twerenbold,
Miriam Reiter,
Stephan Steuer,
Stefano Bassetti,
Katrin Winkler,
Claudia Stelzig,
Corinna Heinisch,
Beatrice Drexler,
Heike Freidank and
Christian Mueller
Abstract
We hypothesized that BNP might be useful in the early diagnosis and risk stratification of patients with acute chest pain.
In a prospective, international multicenter study, BNP was measured in 1075 unselected patients with acute chest pain. The final diagnosis was adjudicated by 2 i...
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PMID: 21531234
PDF is available here.
Abstract
Monoclonal antibodies have emerged as a new class of agents causing drug-related pulmonary involvement in patients with systemic rheumatologic autoimmune diseases. The most frequently associated noninfectious pulmonary diseases are interstitial pneumonia (118 cases reported by August 2010), sarcoid-l...
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PMID: 21531225
PDF is available here.
Philip P Haaf,
Tobias T Reichlin,
Nils N Corson,
Raphael R Twerenbold,
Miriam M Reiter,
Stephan S Steuer,
Stefano S Bassetti,
Katrin K Winkler,
Claudia C Stelzig,
Corinna C Heinisch,
Beatrice B Drexler,
Heike H Freidank and
Christian C Mueller
Abstract
Myocardial ischemia is a strong trigger of B-type natriuretic peptide (BNP) release. As ischemia precedes necrosis in acute myocardial infarction, we hypothesized that BNP might be useful in the early diagnosis and risk stratification of patients with acute chest pain.
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PMID: 21531234
PDF is available here.
Abstract
The concept of pancreatic cancer prevention through surveillance of high-risk patients has come of age. It is cost-effective to provide surveillance of patients who have a lifetime risk of pancreatic cancer that is ≥16%. Studies are currently ongoing that contribute to our understanding of the imag...
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PMID: 21540900
PDF is available here.
Abstract
We suggest that dialysis initiation is justified at GFR levels of 5-9 ml/min/1.73m(2), if accompanied by uremia symptoms or fluid management issues....
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PMID: 21555505
PDF is available here.
Abstract
This study was to compare the performance of three HIV antibody confirmatory assay kits in confirming early HIV infection.
Five HIV antibody-positive plasma specimens were ten-fold serially diluted and then detected by ELISA. The above diluted specimens were detected...
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PMID: 21756787
PDF is available here.
Abstract
We evaluated the positive rate of the Anderson criteria of suspected early glaucomatous visual field defects (GVFDs).
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PMID: 21706836
PDF is available here.
Abstract
Vascular inflammation is a major pathogenetic factor for the progression of an atherosclerotic process and for the development of destructive plaque changes. Now an active search is under way for markers to diagnose acute coronary syndrome at the early stage of development. The paper discusses the ro...
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PMID: 21786607
PDF is available here.
Abstract
Serous exudates were studied by immunoperoxidase and immunofluorescence immunocytochemical assays and by laser flow cytofluorimetry. The current high-tech techniques detect sparse tumor complexes in the exudates at the early metastatic stages, which are undetectable by the routine cytological assay,...
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PMID: 21786609
PDF is available here.
Abstract
Analysis of the results of examining 57 primary and metastatic soft tissues tumors has shown the principal capabilities of immunophenotyping in the cytosmears for differential diagnosis, the determination of histogenesis, and the assessment of their prolferative activity. Its major benefit is short r...
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PMID: 21786610
PDF is available here.
Abstract
We assessed risk factors for advanced stage disease in a population-based study. Study population was all Ontario patients with anterior tongue or floor of mouth cancers diagnosed between 1991 and 2000 (n=2033). Data are from a retrospective chart review. Risk factors included: demographic character...
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PMID: 21612975
PDF is available here.
Abstract
The objective of this study was to compare the performance of the NucliSENS EasyQ HIV-1 v1.2 platform (bioMérieux, France) to the Amplicor HIV-1 DNA test v1.5 (Roche Molecular Systems, Switzerland) in detecting HIV-1 infection in infants using venipuncture-derived whole blood in tubes and dried bloo...
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PMID: 21543563
PDF is available here.
Abstract
The universal definition of myocardial infarction has proved how important the role of biomarkers in the assessment of acute coronary syndrome (ACS) has become. As a result, management of patients with ACS today is more specific and personalized than ever, but there is still a lot of room for improve...
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PMID: 21516070
PDF is available here.
Abstract
The authors review the historical and epidemiological aspects, clinical features and complications of acromegaly while emphasizing the importance of the early diagnosis and treatment. Acromegaly is a rare and mostly sporadic disorder due to excessive production of growth hormone. It is characterized...
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PMID: 21498157
PDF is available here.
Abstract
Silent myocardial ischemia is more frequent in diabetic patients. Nevertheless, its prevalence depends on global cardiovascular risk. Although this is a factor of overmortality, its screening is discussed. In fact, crucial issue is the demonstration of a benefit from revascularizing immediately any c...
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PMID: 21507598
PDF is available here.
Abstract
Multiparametric magnetic resonance imaging (MRI) includes 1 H magnetic resonance spectroscopy, diffusion-weighted imaging, and dynamic contrast-enhanced MRI. These new MRI techniques are increasingly being used to supplement conventional T 2 and T 1-weighted MR sequences in prostate imaging. The f...
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PMID: 21487980
PDF is available here.
Abstract
An early reperfusion of the culprit artery in patients with myocardial infarction leads to a reduction of the infarct size and mortality. The benefit of reperfusion (primary angioplasty or fibrinolysis) is well established in the first 12 hours following the symptom onset, remains discussed between 1...
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PMID: 21489745
PDF is available here.
Abstract
Pressure ulcers are areas of soft tissue breakdown induced by a sustained mechanical stress that damages the skin and underlying tissues. They represent a considerable burden to the society in terms of health care and cost. Yet, techniques for prevention and detection of pressure ulcers still remain...
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PMID: 21626927
PDF is available here.