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Welcome to the Pubget Medical Subject Headings (MESH) browser. Click on a topic or subtopic below to explore related papers. In the gold box is the most recent paper about the current MESH term, and below are 20 related papers.
Laboratory Techniques and Procedures (16):
- Radioligand Assay
- Occult Blood
- Neonatal Screening
- Specimen Handling
- Parasite Egg Count
- Metabolic Clearance Rate
- Age Determination by Skeleton
- Semen Analysis
- Sex Determination by Skeleton
- Hematologic Tests
- Cytodiagnosis
- Urinalysis
- Sex Determination (Analysis)
- Pregnancy Tests
- Immunologic Tests
- Clinical Chemistry Tests
Recent article
Laboratory Techniques and Procedures
Abstract
Hemoglobinopathies are the most common genetic diseases in the world. They are most frequent in areas where malaria is endemic. Sickle cell disease and severe thalassemia require prompt diagnosis. The purpose of this article is to describe first-line techniques for diagnosis in non-specialized labora...
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PMID: 21870542
PDF is available here.
PDF is available here.
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Xenobiotica (41)5 2011
Abstract
We describe a novel, sensitive, homogenous high throughput reporter-based in vitro assay for SUMO protease activity developed by Progenra, Inc. A reporter construct was created by fusing His(6)-tagged small ubiquitin-like modifier (SUMO) to the amino terminus of the reporter enzyme phospholipase A(2...
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PMID: 19107424
PDF is available here.
PDF is available here.
Xenobiotica (41)5 2011
Abstract
We will describe the construction of a fusion protein with the SUMO-tag, its expression in Escherichia coli, and its purification followed by the removal of the SUMO-tag by a SUMO-specific protease in vitro....
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PMID: 19107426
PDF is available here.
PDF is available here.
Abstract
We report a case of a rare Hb variant, Hb Santa Juana, manifesting as a falsely high HbA1c in a 62-year-old patient with type 2 diabetes mellitus. The patient presented with high HbA1c values that persisted despite the intensification of anti-diabetic treatment. His home blood glucose levels were in...
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PMID: 21552778
PDF is available here.
PDF is available here.
Delaware medical journal (83)4 2011
Abstract
Abstract
A large number of cases of undiagnosed fever and joint pain were reported from different parts of the State of Orissa since February 2006. Epidemiological and laboratory investigation were carried out to confirm the cause of emerging illness, which was provisionally suspected as Chikungunya (CHIK) fe...
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PMID: 21441687
PDF is available here.
PDF is available here.
Abstract
Abstract
We have established a diagnostic system based on a manual focusing on rapidity of procedures and prevention of malpractice consisting of a distinction between priority analysis (for blood gas and blood type) and secondary analysis, the development of a blood typing method, adoption of blood sampling...
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PMID: 21476298
PDF is available here.
PDF is available here.
Abstract
We estimate the net selective effect of Wolbachia on its host in a laboratory-adapted population of D. melanogaster, to determine the mechanisms leading to its persistence in the laboratory environment. We found i) no significant effects of Wolbachia infection on female egg-to-adult survival or adul...
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PMID: 21283625
PDF is available here.
PDF is available here.
Abstract
With the persistent challenges towards controlling the HIV epidemic, there is an ongoing need for research into HIV vaccines and drugs. Sub-Saharan African countries--worst affected by the HIV pandemic--have participated in the conduct of clinical trials for HIV vaccines. In Kenya, the Kenya AIDS Vac...
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PMID: 21283743
PDF is available here.
PDF is available here.
Abstract
Chronic liver diseases (CLDs) represent a major cause of morbidity and mortality worldwide. In all etiologies of CLDs, staging of liver fibrosis is essential for both prognosis and management. Until a few years ago, liver biopsy was the only tool for the diagnosis of liver fibrosis in patients with C...
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PMID: 20961196
PDF is available here.
PDF is available here.
Euro surveillance : bulletin europeen sur les maladies transmissibles = European communicable disease bulletin (15)48 2010
Abstract
To identify procedures employed by publicly funded clinical diagnostic laboratories in the United Kingdom (UK) for the detection of Cryptosporidium in community cases of diarrhoea, a telephone survey was conducted between August 2008 and January 2009 of all such laboratories that test stools from co...
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PMID: 21144447
PDF is available here.
PDF is available here.
Abstract
Abstract
The conference Applications of Nucleic Acids Technologies in Molecular Diagnostics (part of TIDES) consisted of four sessions: Regulatory Pathways and Quality Strategies, Manufacturing and Business Considerations for Successful Launch in the Clinical Market, Analytical Methods and Validation, and Ne...
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PMID: 20964604
PDF is available here.
PDF is available here.
Abstract
Abstract
For any analytical system the population mean (μ) number of entities (e.g., cells or molecules) per tested volume, surface area, or mass also defines the population standard deviation (σ = square root(μ)). For a preponderance of analytical methods, σ is very small relative to μ due to their lar...
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PMID: 20635079
PDF is available here.
PDF is available here.
Abstract
Leprosy Review (81)3 2010
Abstract
To understand the characteristics of newly detected leprosy patients at low endemic situation in China in order to provide information for better leprosy control.
A study was carried out using a designed questionnaire in a retrospective method in China in 2007.
Among 1462 new patients studied, the a...
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PMID: 21067058
PDF is available here.
PDF is available here.
Abstract
We have no proper reference indicating the quality of clinical laboratory practice, which should clearly illustrates that better medical tests require more expenses. Japanese Society of Laboratory Medicine was concerned about recent difficult medical economy and issued a committee report proposing a...
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PMID: 20963949
PDF is available here.
PDF is available here.
Abstract
The costs of laboratory tests were surveyed, aiming at realizing medical treatment fees corresponding to the costs of hospital laboratory tests. Using exclusive application software, the costs of blood cell count, peripheral blood and bone marrow, PT, general urinalysis, urine sediment, AST, glucose...
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PMID: 20963952
PDF is available here.
PDF is available here.
Journal of Biophotonics (3)8-9 2010
Abstract
Abstract
Proteins can contain multiple domains each of which is capable of possessing a separate independent function and three-dimensional structure. It is often useful to clone and express individual protein domains to study their biochemical properties and for structure determination. However, the annotat...
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PMID: 20658975
PDF is available here.
PDF is available here.
Abstract
We developed an A(2A) adenosine receptor (AR) FP assay using a newly synthesized fluorescent antagonist of the A(2A)AR (MRS5346), a pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine derivative conjugated to the fluorescent dye Alexa Fluor-488. MRS5346 displayed a K(i) value of 111+/-16nM in rad...
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PMID: 20438717
PDF is available here.
PDF is available here.
Abstract
The present review describes the diagnostic value of the metabolites of epinephrine, norepinephrine, dopamine, and serotonin in the laboratory diagnosis of drug abuse. The metabolism and effects of these substances in health and drug addiction are considered. A procedure for their analysis is presen...
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PMID: 20886714
PDF is available here.
PDF is available here.
Abstract
Risk management is essential for providing patients with safe medical services. In the United States, the Institute for Healthcare Improvement (IHI) launched a 1.5-year national campaign to save 100,000 lives by improving the quality of medical care (100 K campaign) in 2004. They successfully preven...
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PMID: 20860177
PDF is available here.
PDF is available here.
Abstract
We utilized PDCA cycle as required by the international standard in order to establish appropriate safety management and crisis control. We introduced practices for quality improvement and prevention of medical test malpractice proposed by the ISO committee of our medical laboratory and describe the...
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PMID: 20860179
PDF is available here.
PDF is available here.
Abstract
We have developed a work manual in consultation with past incident reports and update this manual regularly. We can reduce medical accidents by including a check system for each task. For pathological diagnosis, we perform some of the same checks as for tissue specimen preparation and can make more...
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PMID: 20860180
PDF is available here.
PDF is available here.
Haemophilia (16) 2010
Abstract
SUMMARY: This review outlines a number of key issues when performing laboratory testing of homeostasis. The effect pre-analytical variables have on the reliability and consistency of screening tests is often forgotten due to a lack of understanding and awareness. This can be improved through educati...
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PMID: 20590860
PDF is available here.
PDF is available here.
Haemophilia (16) 2010
Abstract
SUMMARY: In this paper, the recent developments in the diagnosis and laboratory issues of von Willebrand's disease (VWD) are presented. Dr. Castaman reviews the functional tests available for the diagnosis of VWD and their pathophysiological significance, focusing on which tests are best used in the...
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PMID: 20590859
PDF is available here.
PDF is available here.
Medical Journal of Australia (193)2 2010
Abstract
Pathology test-ordering rates are not higher in practices co-located with PCCs. To the extent inappropriate commercial influences and relationships exist in the pathology sector, GPs' test-ordering behaviour may be unaffected....
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PMID: 20642420
PDF is available here.
PDF is available here.
Abstract
Dipsticks are one of the most commonly used near-patient tests in primary care, but few clinical or dipstick algorithms have been rigorously developed.
To confirm whether previously documented clinical and dipstick variables and algorithms predict laboratory diagnosis of urinary tract infection (UTI...
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PMID: 20594439
PDF is available here.
PDF is available here.
Abstract
The Vitamin D External Quality Assessment Scheme (DEQAS) has been monitoring 25-OHD assay performance since 1989. The scheme has expanded rapidly in recent years and has 670 participants in 35 countries (July 2009). Five samples of human serum are distributed quarterly and the results analyzed to gi...
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PMID: 20302938
PDF is available here.
PDF is available here.
Lab On a Chip (10)17 2010
Abstract
A method for patterning narrow lines of biomolecules onto nitrocellulose membranes using laboratory syringe pumps is described. One syringe pump is used to drive the biomolecule solution through a needle, while another modified syringe pump acts as a one-dimensional translation stage, moving the need...
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PMID: 20607151
PDF is available here.
PDF is available here.
Haemophilia (16 Suppl 5) 2010
Abstract
Haemophilia (16 Suppl 5) 2010
Abstract
Abstract
Abstract
We examined the basic performance of "Microsemi LC-667CRP" (LC-667, HORIBA, Ltd.) which has been newly developed as compact laboratory instrument capable of simultaneous measuring of complete blood count (CBC) including 3-part differentials of white blood cells (WBC) and C-reactive protein (CRP) usi...
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PMID: 20715509
PDF is available here.
PDF is available here.
Abstract
I have tackled these issues. Not only laboratory performance and activity, but the information system for healthcare workers were significantly improved. As a result, appropriate antimicrobial use has been achieved in part....
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PMID: 20715517
PDF is available here.
PDF is available here.
Abstract
We hope our ISO15189 accreditation will be helpful in its dissemination in Japan, thereby playing a role in clinical laboratory standardization, benefiting both clinicians and patients....
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PMID: 20715511
PDF is available here.
PDF is available here.
Abstract
Abstract
A CPD course for pharmacists on integrating laboratory values improved pharmacists' knowledge and confidence and produced changes in practice....
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PMID: 20509351
PDF is available here.
PDF is available here.
Genetics in Medicine (12)6 2010
Abstract
Variants in genes including APOE, F5, HFE, CYP21A2, MEFV, SPINK1, BTD, GALT, and G6PD were found on single nucleotide polymorphism arrays or in the HapMap. Some of these variants may warrant further review to determine their likelihood to trigger incidental findings in the course of genome-wide asso...
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PMID: 20556870
PDF is available here.
PDF is available here.
Abstract
Abstract
Abstract
The methodology allows assessment of the long-term performance of laboratories, taking into account samples with different target values. Outliers in the first step indicate accidental mistakes, outliers in the second and third step point to high analytical variability or bias....
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PMID: 20158445
PDF is available here.
PDF is available here.
Abstract
Laboratory errors made during the pre-analytical phase can have an impact on clinical care. Quality management tools such as Six Sigma may help improve error rates.
To use elements of a Six Sigma model to establish the error rate of test registration onto the laborato...
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PMID: 20299386
PDF is available here.
PDF is available here.
Fertility and Sterility (93)7 2010
Abstract
OBJECTIVE: To compare the semen quality and age-specific changes in men between the 1980s and 2000s. DESIGN: Prospective study. SETTING: Andrology laboratory, University of Calcutta, India. PATIENT(S): A semen sample was obtained from 3729 men presenting for infertility problems in two distinct deca...
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PMID: 19328484
PDF is available here.
PDF is available here.
Anticancer Research (30)5 2010
Abstract
the variety of mathematical methods currently applied, the non-standardized handling of input variables and the potential lack of accuracy due to PSA variability. The aim of this project was to develop a reproducible PSA-DT determination tool which simultaneously provides a PSA-DT error estimation....
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PMID: 20592353
PDF is available here.
PDF is available here.
Metabolic Engineering (12)3 2010
Abstract
We applied gas chromatography-mass spectrometry metabolomics to analyze baby hamster kidney (BHK) cells of various cell ages cultivated in high-cell density perfusion reactors at both laboratory and manufacturing scales. Cell growth, metabolic activity and protein productivity measurements, which ar...
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PMID: 19914390
PDF is available here.
PDF is available here.
Abstract
Abstract
Applied Optics (49)11 2010
Abstract
We used colorimetric measurements and conventional statistical tools to determine the effects on the measurement of the color of cyanobacteria, of the concentration of the microorganisms and their moisture content, as well as of the size of the target area and the minimum number of measurements. It...
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PMID: 20390000
PDF is available here.
PDF is available here.
Abstract
Linear gradient gels, which are polyacrylamide gels having a gradient of increasing acrylamide concentration (and linearly decreasing pore size), can have advantages over fixed-concentration SDS-PAGE gels. First, a much greater range of protein M(r) values can be separated on a linear gradient gel t...
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PMID: 20360365
PDF is available here.
PDF is available here.
Abstract
Accreditation according to international standards can decrease differences regarding the management of critical values across laboratories of different countries. However, the issues concerning critical limits should be debated and a consensus critical values list should be considered. Automated sy...
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PMID: 20128733
PDF is available here.
PDF is available here.
Applied Spectroscopy (64)4 2010
Abstract
Raman spectra of Gram-positive and Gram-negative plant bacteria have been measured with micro-Raman spectrometers equipped with 785 and 514.5 nm lasers. The Gram-positive bacteria Microbacterium testaceum, Paenibacillus validus, and Clavibacter michiganensis subsp. michiganensis have strong caroteno...
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PMID: 20412629
PDF is available here.
PDF is available here.
Abstract
Rapid accurate laboratory diagnosis is necessary for effective malaria management. In Mali, meeting this prerequisite is impeded by underuse of laboratory diagnosis by clinicians, absence of qualified laboratory facilities in some locations, and poor continuous professional education of laboratory t...
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PMID: 20486352
PDF is available here.
PDF is available here.
Abstract
Abstract
We conclude that even in the setting of low resource tertiary centres found in many developing countries, challenges could be overcome and standard acceptable patency rates obtained in the microsurgery laboratory ....
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PMID: 20348985
PDF is available here.
PDF is available here.
Abstract
In 1947 the Medical Research Council of Britain established the Laboratory Animals Bureau in order to develop national standards of animal production that would enable commercial producers better to provide for the needs of laboratory animal users. Under the directorship of William Lane-Petter, the...
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PMID: 20575490
PDF is available here.
PDF is available here.
Abstract
This study indicates that liposarcomas are heterogeneous tumors. Expert assessment and implementation of molecular biological analysis are valuable for adequate classification as a basis for treatment decisions....
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PMID: 20183915
PDF is available here.
PDF is available here.