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Welcome to the Pubget Medical Subject Headings (MESH) browser. Click on a topic or subtopic below to explore related papers. In the gold box is the most recent paper about the current MESH term, and below are 20 related papers.
Fetus (7):
Recent article
Fetus
Abstract
We used a flow cytometric method specifically designed for use in a routine hematology analyzer. Pregnant women were recruited through midwives. The participating laboratories used the FMH QuikQuant method (Trillium Diagnostics, Brewer, ME) in a CELL-DYN Sapphire hematology analyzer (Abbott Diagnost...
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PMID: 21917687
PDF is available here.
PDF is available here.
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Abstract
Before effective antiretroviral treatment was introduced in children with HIV, cardiovascular complications were a major cause of morbidity and mortality. Now that antiretroviral treatment is the standard of care in this population, there has been a shift from fulminant cardiovascula...
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PMID: 21643782
PDF is available here.
PDF is available here.
Abstract
Noninvasive prenatal determination of fetal sex using cell-free fetal DNA provides an alternative to invasive techniques for some heritable disorders. In some countries this testing has transitioned to clinical care, despite the absence of a formal assessment of performance....
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PMID: 21828326
PDF is available here.
PDF is available here.
Genes & Development (25)15 2011
Abstract
Maturation of hematopoietic stem cells (HSCs) from fetal to adult state and differentiation to progenitors are thought to follow a one-way street. In this issue of Genes & Development, He and colleagues (pp. 1613-1627) show that overexpression of Sox17 can convert adult multipotentia...
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PMID: 21828265
PDF is available here.
PDF is available here.
Genes & Development (25)15 2011
Abstract
We previously showed that the transcription factor SOX17 is expressed by fetal, but not adult, HSCs and is required for the maintenance of fetal and neonatal, but not adult, HSCs. In the current study, we show that ectopic expression of Sox17 in adult HSCs and transiently reconstituting multipotent...
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PMID: 21828271
PDF is available here.
PDF is available here.
Abstract
We used high resolution 244K oligonucleotide array in addition to conventional karyotype and molecular (fluorescent in situ hybridization, microsatellite markers analysis) techniques in two independent probands carrying a deletion 13q13 to 13q21. First patient was a 3-year-old girl with mental retar...
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PMID: 21741501
PDF is available here.
PDF is available here.
Abstract
In the context of increasing extinction rates and the potential loss of essential evolutionary biological and anthropological information, it is an important task to support efforts to prepare, preserve, and curate collections of histological brain sections; to disseminate informatio...
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PMID: 21599701
PDF is available here.
PDF is available here.
Abstract
The Zagreb Collection of developing and adult human brains was founded in 1974 by Ivica Kostović and consists of 1,278 developing and adult human brains, including 610 fetal, 317 children, and 359 adult brains. It is one of the largest collections of developing human brains. The col...
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PMID: 21599691
PDF is available here.
PDF is available here.
Abstract
Journal of Proteomics (74)4 2011
Abstract
A large series of protein pathway components have been shown to be dysregulated in Down syndrome (DS) brain. No information about pathomechanisms linked to the trisomic state can be obtained from adult DS brain, however, as neurodegeneration occurs from the fourth decade. The aim of...
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PMID: 21262400
PDF is available here.
PDF is available here.
Abstract
We studied the properties of perivascular cells from a novel source, the foetal human umbilical cord (HUC) collected from pre-term newborns. By immunohistochemistry and flow cytometry we show that pre-term/foetal HUCs contain more perivascular cells than their full-term counterparts (2.5%versus 0.15...
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PMID: 20219017
PDF is available here.
PDF is available here.
Reproductive Sciences (18)3 2011
Abstract
We conclude that enhanced cortisol production in LTH adrenals is the result of enhanced protein expression of StAR and potential downstream signaling pathways....
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PMID: 21079237
PDF is available here.
PDF is available here.
Abstract
We define the gene expression network topology of cardiac hypertrophy and failure and the extent of recapitulation of fetal gene expression programs in failing and hypertrophied adult myocardium.
We assembled all myocardial transcript data in the Gene Expression Omnibus (n=1617). Bec...
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PMID: 21127201
PDF is available here.
PDF is available here.
Abstract
Mice models are an important way to understand the relation between the fetus with cleft palate and changes of maternal biofluid. This paper aims to develop a metabonomics approach to analyze dexamethasone-induced cleft palate in pregnant C57BL/6J mice and to study the relationship between the chang...
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PMID: 20814536
PDF is available here.
PDF is available here.
Abstract
Hypospadias is a common congenital anomalies, yet its molecular basis remains unknown. Recent studies have linked perturbations in the Hedgehog signaling pathway to hypospadias. However, the expression of Sonic hedgehog (Shh) has not been reported during genital development. Immunohi...
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PMID: 21434830
PDF is available here.
PDF is available here.
Epigenetics (6)1 2011
Abstract
We identify biallelic and variably expressed genes that may inform on overall epigenetic stability. As differential methylation did not correlate with imprinted expression changes we propose that other epigenetic effectors are adversely influenced by the in vitro environment. Since DMR integrity was...
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PMID: 20864803
PDF is available here.
PDF is available here.
Abstract
Fetal rat epiglottis and its developmental potential in ectopic transplants under the influence of the epigenetic drug was investigated. Epiglottises from 17-days-old rat embryos were transplanted under kidney capsules of adult rats for 14 days. 5-azacytidine (5 mg/kg) was injected i...
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PMID: 21196336
PDF is available here.
PDF is available here.
Abstract
Presence of foreign tissue in a host's body would immediately lead to a strong immune response directed to destroy the alloantigens present in fetus and placenta. However, during pregnancy, the semiallogeneic fetus is allowed to grow within the maternal uterus due to multiple mechanisms of immune to...
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PMID: 20941623
PDF is available here.
PDF is available here.
Abstract
We made a molecular analysis through array comparative genomic hybridization (array CGH) of a group of fetuses with prenatal ultrasound diagnosis of CDH and normal G-banded karyotypes. A whole genome BAC-array CGH, composed of approximately 5000 BAC clones, was carried out on blood samples from fetu...
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PMID: 21341218
PDF is available here.
PDF is available here.
Ukrainskij biokhimicheskij zhurnal/Ukrayins'kij biokhimichnij zhurnal/Ukrainian biochemical journal (83)2 2011
Abstract
We observed previously in other experimental models (partial hepatectomy, chronic alcohol poisoning and hypercholesterolemia). In conclusion, cell therapy may be considered as the universal method for correction of disorders in regulation of free-radical processes in various experimental pathologies...
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PMID: 21851050
PDF is available here.
PDF is available here.
Abstract
We studied the relation of first trimester nuchal translucency and first trimester biochemical markers using low molecular weight heparin (LMWH) at 11-14 weeks of gestation.
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PMID: 21485734
PDF is available here.
PDF is available here.
Cuadernos de bioetica : revista oficial de la Asociacion Espanola de Bioetica y Etica Medica (21)73 2010
Abstract
We doctors, find ourselves, both in the medical and ethical area, upon two patients: mother and son. Doctors have the same therapeutical responsibilities upon them. What alternatives would be presented in our country if the Jehovah's Witness's transfusional negative was accepted, and we had a pregna...
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PMID: 21090844
PDF is available here.
PDF is available here.
Zhongguo shi yan xue ye xue za zhi / Zhongguo bing li sheng li xue hui = Journal of experimental hematology / Chinese Association of Pathophysiology (18)6 2010
Abstract
The aim of this study was to investigate the feasibility of using fetal short tandem repeat (STR) loci in maternal plasma as gender-independent fetal DNA marker. DNA from maternal plasma sample was extracted using QIAamp DNA Kit. AmpF1 STR profiler box was used to amplify 9 different polymorphic shor...
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PMID: 21176384
PDF is available here.
PDF is available here.
Free Radical Research (44)11 2010
Abstract
Despite their being good markers of oxidative stress for clinical use, little is known about ubiquinol-10 (reduced coenzyme Q10) and ubiquinone-10 (oxidized coenzyme Q10) levels in foetuses and their mothers. This study investigates oxidative stress in 10 healthy maternal venous, umbilical arterial...
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PMID: 20815779
PDF is available here.
PDF is available here.
Abstract
To study the role of antenatal glucocorticoid (dexamethasone and betamethasone) on bone morphogenetic protein (BMP) signal transduction of the rat fetal lungs.
Fifteen pregnant rats were randomly divided into five groups: the rats treated with dexamethasone for 1 day (1D-DEX) or 3 days (3D-DEX), wit...
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PMID: 21083986
PDF is available here.
PDF is available here.
Abstract
We aim to provide an overview of the current knowledge on the ABCB1 and ABCG2 transporter expression profiles in the placenta and fetal tissues in humans relative to other species.
The available information on ABCB1 and ABCG2 temporal expression profiles in placenta and fetus indicates rather good c...
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PMID: 20738225
PDF is available here.
PDF is available here.
Abstract
Noninvasive prenatal diagnosis based on detection of fetal cell-free DNA is hampered when mother and father are both carriers for the same autosomal recessive mutation.
To compare the diagnosis of Bart's hydrops fetalis using conventional Gap-PCR analysis of fetal cells/tissues with the measurement...
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PMID: 21114201
PDF is available here.
PDF is available here.
Pediatric Research (68)5 2010
Abstract
In complicated labor, neonatal outcome may depend not only on the extent of fetal asphyxia and acidosis but also on the effects on the fetal cardiovascular system of reactive oxygen species (ROS) generated during the ischemia-reperfusion (I/R) associated with repeated compressions of the umbilical c...
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PMID: 20613682
PDF is available here.
PDF is available here.
Pediatric Research (68)5 2010
Abstract
We hypothesized that maternal creatine supplementation from mid-pregnancy would protect the diaphragm of the newborn spiny mouse from the effects of intrapartum hypoxia. Pregnant mice were fed a control or 5% creatine-supplemented diet from mid-gestation. On the day before term, intrapartum hypoxia...
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PMID: 20639795
PDF is available here.
PDF is available here.
Abstract
Our data indicate that the terminal maturation and enucleation of human primitive RBCs occurs in first trimester placental villi. Extravascular ζ-globin(+) primitive erythroid cells were found in placental villi between 5-7 weeks of development, at which time the frequency of enucleated RBCs was hi...
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PMID: 20628147
PDF is available here.
PDF is available here.
British Journal of Cancer (103)8 2010
Abstract
The majority of testicular germ cell cancers develop through a pre-invasive carcinoma in situ (CIS) stage. The CIS cell is a neoplastic counterpart of foetal germ cells. During their development, foetal germ cells undergo extensive and essential epigenetic modifications, but little is known about ep...
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PMID: 20823885
PDF is available here.
PDF is available here.
Abstract
Fetal hearts show a remarkable ability to develop under hypoxic conditions. The metabolic flexibility of fetal hearts allows sustained development under low oxygen conditions. In fact, hypoxia is critical for proper myocardial formation. Particularly, hypoxia inducible factor 1 (HIF-...
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PMID: 20712587
PDF is available here.
PDF is available here.
Abstract
Ustekinumab is a human monoclonal antibody that binds to the p40 subunit of interleukin (IL) 12 and IL-23 and inhibits their pharmacological activity. To evaluate potential effects of ustekinumab treatment during pregnancy, developmental studies were conducted in cynomolgus macaques....
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PMID: 20540088
PDF is available here.
PDF is available here.
Abstract
We describe the efficient derivation of connective tissue progenitors (CTPs) from hESC lines and fetal tissues. The CTPs were significantly expanded and induced to generate tendon tissues in vitro, with ultrastructural characteristics and biomechanical properties typical of mature tendons. We descri...
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PMID: 20486794
PDF is available here.
PDF is available here.
Food and Chemical Toxicology (48)10 2010
Abstract
We questioned whether this mycotoxin, administered during known critical exposure periods such as the fetal period and the first days of life, at doses compatible with mean daily intake in humans, could have an effect on mammary gland development in rodents. Wistar female rats were exposed to zearal...
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PMID: 20637251
PDF is available here.
PDF is available here.
Biology of Reproduction (83)4 2010
Abstract
We examined whether erythromycin would eradicate intra-amniotic ureaplasma infections in pregnant sheep. At Gestational Day (GD) 50 (term, GD 150), pregnant ewes received intra-amniotic injections of erythromycin-sensitive Ureaplasma parvum serovar 3 (n = 16) or 10B medium (n = 16). At GD 100, amnio...
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PMID: 20610808
PDF is available here.
PDF is available here.
Abstract
Our potential for further testing is limited; thus far, no other congenital disorders of glycosylation-positive samples have been available. Verification of our results in another laboratory with the exclusion of several potentially pertinent variables is advisable....
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PMID: 20528096
PDF is available here.
PDF is available here.
Abstract
I report on an additional case of a male fetus with a mosaic male karyotype mos 46,X,der(Y)t(Y;1)(q12;q21)[31]/46,XY[21] and multiple anomalies that included "teardrop"-shaped head with a triangular face, a short-nasal bridge with upturned nose, microretrognathia, microtia, kyphoscoliosis, oligodact...
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PMID: 20684010
PDF is available here.
PDF is available here.
Abstract
The safe prescribing, use, administration, and monitoring of medications are an important component of patient safety efforts and are of particular importance to the obstetrician/gynecologist. Safe use of medications requires a team-based approach focused on medication safety with effective 2-way co...
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PMID: 20661034
PDF is available here.
PDF is available here.
Pediatric Research (68)3 2010
Abstract
We tested the hypothesis that IL-1 mediates the systemic and pulmonary induction of MCP-1 and MCP-2 in response to lipopolysaccharide (LPS)-induced chorioamnionitis. MCP-1 mRNA, MCP-2 mRNA, and MCP-1 protein expression were measured in two models: 1) intra-amniotic LPS and 2) intra-amniotic recombin...
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PMID: 20517173
PDF is available here.
PDF is available here.
Abstract
We tested the hypothesis that the differential effects of BPA and MXC on LH surge system involved changes in hypothalamic gonadotropin-releasing hormone (GnRH) and estrogen receptors (ESR), ESR1 and ESR2, mRNA expression. Pregnant sheep were given daily injections of cottonseed oil (controls), MXC,...
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PMID: 20621667
PDF is available here.
PDF is available here.
Abstract
We have used collision-induced dissociation mass spectrometry to examine the architecture of the polydisperse assemblies of alpha-crystallin. For total alpha-crystallin isolated directly from fetal calf lens using size-based chromatography, the alphaB-crystallin subunit was found to be preferentiall...
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PMID: 20535821
PDF is available here.
PDF is available here.
Abstract
I psychiatric disorders) had higher uterine artery PI than those scoring below 20.This was significant after adjusting for alcohol and nicotine use, as well as when nicotine dependence was considered. This work highlights the complexities of the relationship between increased measures of distress an...
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PMID: 20119861
PDF is available here.
PDF is available here.
Abstract
We aimed to analyse the immunohistochemical distribution of Lf in human embryonal and fetal bone and cartilaginous tissues at different gestational weeks in order to evaluate whether a role for this protein might be proposed also in human osteogenesis. Bone and cartilaginous specimens were taken at...
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PMID: 20443779
PDF is available here.
PDF is available here.
Abstract
The aims of this study were (i) to determine whether NSCs (neural stem cells) could be isolated from the brain of porcine fetuses at intermediate and late gestational age and (ii) to determine if these stem cells could be differentiated in vitro into osteogenic and neurogenic lineages following tran...
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PMID: 20423329
PDF is available here.
PDF is available here.
Abstract
The ability of human embryonic stem cells (hESCs) to differentiate into essentially all somatic cell types has made them a valuable tool for studying human development and has positioned them for broad applications in toxicology, regenerative medicine, and drug discovery. This unit describes a proto...
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PMID: 20814935
PDF is available here.
PDF is available here.
Abstract
Genes & Development (24)15 2010
Abstract
We address the vexing issue of how developmental restriction is achieved in Down syndrome acute megakaryoblastic leukemia (DS-AMKL), characterized by the triad of fetal origin, mutated GATA1 (GATA1s), and trisomy 21. We demonstrate overactivity of insulin-like growth factor (IGF) signaling in authen...
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PMID: 20679399
PDF is available here.
PDF is available here.
Chemosphere (80)10 2010
Abstract
The main objective of the present study was to gain knowledge about the disposition of the PCB congeners 118 and 153 in a sheep model where ewes were given oral doses of PCB in two consecutive gestations. The study aimed to investigate how maternal exposure with PCBs affected tissue concentrations i...
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PMID: 20605042
PDF is available here.
PDF is available here.
Abstract
Pon3, a putative circulating antioxidant, was systemically up-regulated in late-gestation rat, sheep, and human fetuses and is a candidate therapeutic in preterm human infants....
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PMID: 20463093
PDF is available here.
PDF is available here.
Journal of Anatomy (217)2 2010
Abstract
We examined the immunohistochemical expression of intermediate filaments in skeletal muscles of the head, neck and thorax in 12 mid-term human fetuses at 9-18 weeks of gestation. We also used immunohistochemistry to localize the expression of the myosin heavy chain and silver impregnation to identif...
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PMID: 20500537
PDF is available here.
PDF is available here.
Abstract
We examined AhR protein expression in human placentas from normal (N) and severe preeclamptic (sPE) pregnancies, as well as human fetal tissues from the second trimester of pregnancy, using immunohistochemistry and/or Western blot analysis. In the placentas, the AhR immunoreactivity was present prim...
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PMID: 20354149
PDF is available here.
PDF is available here.
Abstract
Folia morphologica (69)3 2010
Abstract
Fusion of the neural arches was studied in 6 serially sectioned human foetuses aged 9 and 10 weeks. In foetuses of 9 weeks, the completion of arches was observed in the cervical, upper thoracic, and middle thoracic regions of the vertebral column. During the 10th week of development, fusion of neura...
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PMID: 21154289
PDF is available here.
PDF is available here.
Folia morphologica (69)3 2010
Abstract
The arterial fibrous rings were investigated in human embryos aged 7 and 8 weeks under light and scanning electron microscopes. In the present study it was shown that the arrangement of collagen and formation of fibres changes rapidly within one week. In the 7(th) week there are no collagen fibres a...
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PMID: 21154290
PDF is available here.
PDF is available here.
Abstract
We examined semiserial sections of 16 fetuses between 15 and 30 weeks of gestation (6 males and 10 females). The subcutaneous part of the EAS (EASsc) developed along the male perineal raphe and extended posteriorly. Thus, the male EAS was characterized by anterior protrusion of the subcutaneous musc...
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PMID: 20882767
PDF is available here.
PDF is available here.
Abstract
Epithelial/ectodermal plug formation in the developing nose, ear, and eye regions is followed by canalization/recanalization mediated by cell death. However, the mechanism is not well understood. Recently, substance P (SP)-mediated cell death, rather than cell apoptosis, has been reported in neurona...
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PMID: 20882765
PDF is available here.
PDF is available here.
Obstetrics & Gynecology (116 Suppl 2)supplement 2010
Abstract
We report a case of a retained single intrauterine pregnancy after an elective vacuum aspiration of a dichorionic-diamniotic twin gestation. CASE: A patient presented to the emergency department reporting vaginal spotting, breast engorgement, and lower abdominal cramping for the previous 2 weeks. Th...
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PMID: 20664430
PDF is available here.
PDF is available here.
Experimental Hematology (38)8 2010
Abstract
Fus(-/-) fetal livers developed normally, except for a mild reduction in numbers of hematopoietic stem and progenitor cells compared to wild-type. The proliferation and differentiation of Fus(-/-) hematopoietic progenitors were normal in vitro. However, the number of colony-forming cells present in...
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PMID: 20412831
PDF is available here.
PDF is available here.
Abstract
We immunolocalized lymphatic and vascular blood vessels in 12- and 14-week-old human fetal knee joint tissues using a polyclonal antibody to a lymphatic vascular endothelium specific hyaluronan receptor (LYVE-1) and a monoclonal antibody to podoplanin (mAb D2-40). A number of lymphatic vessels were...
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PMID: 20334573
PDF is available here.
PDF is available here.