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Welcome to the Pubget Medical Subject Headings (MESH) browser. Click on a topic or subtopic below to explore related papers. In the gold box is the most recent paper about the current MESH term, and below are 20 related papers.
Endocrine System (4):
Recent article
Endocrine System
Annales d'Endocrinologie (72)5 2011
Abstract
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Abstract
Pathologic hyperplasia of various pancreatic endocrine cells is rare but has been long known. β cell hyperplasia contributes to persistent hyperinsulinemic hypoglycemia of infancy, which is commonly caused by mutations in the islet ATP-sensitive potassium channel, and to non-insulinoma pancreatogeno...
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PMID: 21245985
PDF is available here.
PDF is available here.
Diabetes forecast (63)11 2010
Abstract
Abstract
The aim of this study was to evaluate long-term changes in endocrine and metabolic parameters and body mass index in women with polycystic ovary syndrome (PCOS) who were treated with metformin over 2 years without caloric restriction.
Twenty-six obese women with PCOS were treated with metformin over...
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PMID: 19998243
PDF is available here.
PDF is available here.
Abstract
Our analysis revealed the regulation of inflammatory processes via thymic hormones that could be prospective for therapeutic application. This regulation may be mediated through thymic hormone effects on peripheral immune cell activities and bidirectional coupling between thymic hormones and the hyp...
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PMID: 20536297
PDF is available here.
PDF is available here.
Abstract
Opioids are widely used for the management of acute and chronic pain. They are also abused for recreational purposes. Long term use may lead to abnormalities in the endocrine system. The axis mainly affected is the gonadal axis leading to hypogonadism. However adrenal insufficiency and growth hormon...
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PMID: 20486065
PDF is available here.
PDF is available here.
Abstract
Neoadjuvant endocrine therapy improves surgical outcomes for postmenopausal women with bulky hormone receptor-positive breast cancer. Recent studies indicate that this approach may also be used in the management of smaller tumors with the hope of predicting outcomes from adjuvant endocrine manipulat...
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PMID: 20620931
PDF is available here.
PDF is available here.
Abstract
We have compared fracture repair between Cyp24a1-/- mice and wild-type controls. We have observed a delay in the mineralization of the cartilaginous matrix of the soft callus in Cyp24a1-/- mutant animals, accompanied by reduced expression of chondrocyte marker genes. These results show that Cyp24a1...
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PMID: 20144713
PDF is available here.
PDF is available here.
Abstract
Since its discovery in the 1920s, relaxin has enjoyed a reputation as a peptide hormone of pregnancy. However, relaxin and other relaxin family peptides are now associated with numerous non-reproductive physiologies and disease states. The new millennium bought with it the sequence of the human geno...
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PMID: 20213277
PDF is available here.
PDF is available here.
Abstract
We present a review of salient developments over the past decade that have helped shape the adjuvant systemic therapy of today....
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PMID: 20497918
PDF is available here.
PDF is available here.
Journal of Autoimmunity (34)4 2010
Abstract
We incidentally identified 26 patients (61% female) with an IgG that bound selectively to neural elements in enteric ganglia, sympathetic nerve trunks and discrete nerve tracts in mid-brain and hind-brain. The target antigen was identified as peripherin, a 55kDa - type III intermediate filament prot...
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PMID: 20061119
PDF is available here.
PDF is available here.
Acta clinica Croatica (49)2 2010
Abstract
Abstract
In teleosts, growth hormone (GH) production is governed by multiple neuroendocrine factors from the hypothalamus and other regulators from the pituitary and peripheral organs. Exploring the principles followed by pituitary somatotropes when differentiating and integrating the signals from these regu...
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PMID: 20596912
PDF is available here.
PDF is available here.
Biology of Reproduction (82)4 2010
Abstract
Knowledge of fish reproduction is of high relevance to basic fish biology and comparative evolution. Furthermore, fish are excellent biomedical models, and the impact of aquaculture on worldwide food production is steadily increasing. Consequently, research on fish reproduction and the potential mod...
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PMID: 19864315
PDF is available here.
PDF is available here.
Parasitology (137)4 2010
Abstract
These results demonstrate significant negative effects on the reproductive function of wild roach infected by the tapeworm L. intestinalis collected from a site with low contamination....
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PMID: 19961656
PDF is available here.
PDF is available here.
Abstract
The kisspeptin/kisspeptin receptor (KISS1R) system is a critical regulator of reproductive function. The kisspeptins are potent stimulators of the hypothalamic-pituitary-gonadal (HPG) axis via their actions ongonadotropin-releasing hormone. Therefore, kisspeptins represent putative drug targets for...
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PMID: 20336591
PDF is available here.
PDF is available here.
Abstract
Obstructive sleep apnoea (OSA) is a prevalent disorder with significant co-morbidities. Presently only rarely, treatments for obstructive sleep apnoea are curative. More typically, this is a disease that requires lifelong intervention and commitment from both the patients and healthcare providers. I...
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PMID: 20308749
PDF is available here.
PDF is available here.
Ecotoxicology (19)2 2010
Abstract
European eel (Anguilla anguilla (L.)) stocks are in decline in most of their geographical distribution and their status is considered below safe biological limits. Recently, there is an increasing awareness that spawner quality might be an essential element in the decline of the spec...
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PMID: 19806452
PDF is available here.
PDF is available here.
Endocrine Journal (57)1 2010
Abstract
We discuss recent advances in the understanding of autocrine/paracrine actions of BMPs in the systemic regulation of endocrine function....
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PMID: 19875899
PDF is available here.
PDF is available here.
Abstract
In mammals, the adipose organ is composed of white adipocytes (primary site in energy storage) and of brown adipocytes (specialized in thermogenesis). Adipocytes arise from mesenchymal stem cells (MSCs) by a sequential pathway of differentiation. MSCs develop either from ectoderm or mesoderm and com...
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PMID: 20551665
PDF is available here.
PDF is available here.
Abstract
I and II, are also produced by adipose tissue, which could influence appetite and the reproductive axis. Targets of leptin in the hypothalamus include neuropeptide Y, proopiomelanocortin and kisspeptin. Transsynaptic connection of hypothalamic neurons to porcine adipose tissue may result in a direct...
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PMID: 20551666
PDF is available here.
PDF is available here.
Abstract
Oncology Reports (23)1 2010
Abstract
We further investigated the effects of DEHP, BPA as well as 17beta-estradiol (E2) on the invasion and metastasis of human neuroblastoma SK-N-SH cells in vitro. SK-N-SH cells expressed estrogen receptor (ER)-beta, matrix metalloproteinases-2 (MMP-2), MMP-9 and tissue inhibitor of matrix metalloprotei...
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PMID: 19956873
PDF is available here.
PDF is available here.
Abstract
Vitamin D insufficiency and deficiency have been identified as having a correlation with poor clinical outcomes in patients with chronic kidney disease (CKD). The availability of vitamin D for metabolism into 25(OH)D and the ability to further metabolize to 1,25(OH)D are known to hav...
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PMID: 20333900
PDF is available here.
PDF is available here.
Abstract
I try to provide an overview of the evolution from endocrine cell types in invertebrates to the higher mammals and focus on what has been reported in the literature and some of our own experiences and also include a description of other hormones reported to be found in islets....
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PMID: 20217492
PDF is available here.
PDF is available here.
Abstract
We will discuss the main transcription factors involved in pancreas specification and beta-cell formation....
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PMID: 20217494
PDF is available here.
PDF is available here.
Abstract
Type 2 diabetes mellitus (T2D) arises when the endocrine pancreas fails to secrete sufficient insulin to cope with the metabolic demand because of beta-cell secretory dysfunction and/or decreased beta-cell mass. Defining the nature of the pancreatic islet defects present in T2D has been difficult, i...
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PMID: 20217511
PDF is available here.
PDF is available here.
Abstract
The singular gene for a peptide hormone is expressed not only in a specific endocrine cell type but also in other endocrine cells as well as in entirely different cells such as neurons, adipocytes, myocytes, immune cells, and cells of the sex-glands. The cellular expression pattern for each gene var...
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PMID: 19859674
PDF is available here.
PDF is available here.
Abstract
Over a period of two years, 72 adult males with liver cirrhosis of different aetiologies were studied in terms of clinical and biochemical evidence of endocrine dysfunctions related to hypothalamic-pituitary-gonadal axis and the thyroid status, and compared with 40 age-matched control subjects. With...
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PMID: 20509471
PDF is available here.
PDF is available here.
Abstract
The low-carbohydrate, high-protein diet (Diet 1) appeared to offer certain advantages to working dogs, including higher apparent nutrient digestibility, slower release of glucose into the bloodstream, and reduced large intestinal fermentation of carbohydrate. CLINICAL RELEVANCE: A low-carbohydrate,...
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PMID: 19966890
PDF is available here.
PDF is available here.
Psychoneuroendocrinology (34 Suppl 1) 2009
Abstract
We summarize data collected in recent years which clearly indicate that the opioid-induced effects on steroid hormones depend on the opioid used and in some cases on the sex of the subject. Indeed morphine is able to reduce hormones like testosterone and cortisol in both male and female subjects in...
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PMID: 19540049
PDF is available here.
PDF is available here.
Medicina Clínica (133)9 2009
Abstract
Abstract
Within the last decade, several studies have investigated whether adjuvant treatment of breast cancer affects cognitive function. A number of prospective studies have demonstrated inconsistent results regarding whether chemotherapy affects cognitive function. Approximately half of the studies demons...
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PMID: 19702450
PDF is available here.
PDF is available here.
Abstract
Abstract
A three-spined stickleback (Gasterosteus aculeatus) cDNA array and one-dimensional 1H nuclear magnetic resonance (NMR) spectroscopy-based metabolomics approach, together with individual biomarkers,were employed to investigate the responses of male sticklebacks to polycyclic aromatic hydrocarbon expo...
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PMID: 19746735
PDF is available here.
PDF is available here.
Abstract
We focus on novel roles of PGRN as a sex steroid-responsible gene in the developing and adult rodent brain. While the developing brain is feminine by default, hormone exposure, including androgen and estrogen, induces masculinization during the critical period. We have shown that PGRN is a sex stero...
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PMID: 19721334
PDF is available here.
PDF is available here.
Abstract
We examined the associations between Hg and endocrine function (adrenocortical responses and plasma thyroid hormone concentrations) of insectivorous tree swallow nestlings adjacent to a Hg-contaminated river and nearby reference rivers in Virginia. Nestlings from the contaminated sites had blood Hg...
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PMID: 19731714
PDF is available here.
PDF is available here.
Bioscience Reports (29)4 2009
Abstract
We provide an overview of the synaptotagmin family, and review the recent mouse genetic studies aimed at understanding the functions of synaptotagmins in neurotransmission and endocrine-hormone secretion. Also, we discuss potential roles of synaptotagmins in non-traditional endocrine systems....
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PMID: 19500075
PDF is available here.
PDF is available here.
Abstract
Strahlentherapie und Onkologie (185 Suppl 2)s2 2009
Abstract
Molecular Endocrinology (23)8 2009
Abstract
Obesity and obesity-related disorders, such as type 2 diabetes, hypertension, and cardiovascular disease, are epidemic in Western countries, particularly the United States. The conventional wisdom holds that obesity is primarily the result of a positive energy balance, i.e. too many calories in and...
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PMID: 19372238
PDF is available here.
PDF is available here.
Abstract
Molecular Endocrinology (23)7 2009
Abstract
We postulate that the increased inflammatory response and NF-kappaB activation promote uterine contractility via 1) direct activation of contractile genes (e.g. COX-2, oxytocin receptor, and connexin 43) and 2) impairment of the capacity of PR to mediate uterine quiescence. PR function near term may...
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PMID: 19282364
PDF is available here.
PDF is available here.
Abstract
This review reports current knowledge regarding the roles that cadmium (Cd), mercury (Hg), arsenic (As), lead (PB), manganese (Mn), and zinc (Zn) play as endocrine-disrupting chemicals (EDCs). The influence of these metals on the endocrine system, possible mechanisms of action, and consequent health...
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PMID: 19466673
PDF is available here.
PDF is available here.
Abstract
Until recently, the popular notion that psychoemotional stress can have an impact on hair growth has been treated with skepticism and assigned to the realm of folklore by many authorities. Yet it has long been appreciated that episodes of alopecia areata (AA) have occurred after severely stressful l...
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PMID: 19434088
PDF is available here.
PDF is available here.
Abstract
We concluded that there are five main endocrine-related mechanisms of Hg across these systems: (a) accumulation in the endocrine system; (b) specific cytotoxicity in endocrine tissues; (c) changes in hormone concentrations; (d) interactions with sex hormones; and (e) up-regulation or down-regulation...
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PMID: 19280433
PDF is available here.
PDF is available here.
Abstract
Abstract
The standard gluco-tolerance test was carried out in 104 healthy women, 20-30 years living in Archangelsk at different year periods (October, March, December and June). The higher spare capacities levels were determined for glucose, lactate and pyruvate against the background of lactate dehydrogenas...
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PMID: 19505044
PDF is available here.
PDF is available here.
Abstract
We describe a 17-year-old female with a phenotype consistent with GPS. Being the oldest reported patient, she is the first one showing severe symptomatic osteoporosis and endocrine abnormalities including primary hypothyroidism and delayed puberty. We suggest that these novel findings are also manif...
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PMID: 19208376
PDF is available here.
PDF is available here.
Abstract
We report on two children from an inbred Arab family with anterior segment anomalies of the eyes, growth retardation, associated with small pituitary gland, and endocrine abnormalities. The features in the sibs in this report are similar to those described in Peters-plus syndrome. However, small pit...
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PMID: 19161143
PDF is available here.
PDF is available here.
Child's Nervous System (25)2 2009
Abstract
This LESS seems to be a simple and practical tool to quantify late effects in former brain tumor patients. Although both groups differ significantly with regard to neurocognitive parameters and severity of late effects, this does not apply for all QoL outcomes. Neurological late effects seem to be m...
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PMID: 18974990
PDF is available here.
PDF is available here.
Abstract
We investigated the hypothesis that DHEA metabolism may be increased in a reactive prostate stroma environment in the presence of proinflammatory cytokines such as transforming growth factor beta1 (TGFbeta1), and further, whether red clover extract, which contains a variety of compounds including is...
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PMID: 19141600
PDF is available here.
PDF is available here.
Oncology (Basel) (77 Suppl 1) 2009
Abstract
Endocrine therapy, the first targeted therapy in oncology, is the most successful systemic therapy in the management of estrogen receptor (ER)-positive breast cancer. Approximately 50% of patients with advanced disease do not respond to first-line treatment with tamoxifen, and many women who receive...
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PMID: 20130429
PDF is available here.
PDF is available here.
Oncology (Basel) (77 Suppl 1) 2009
Abstract
These results are largely irrespective of age, use of chemotherapy or other tumor features. Moreover, the expert panel of the St. Gallen Conference accepted both tamoxifen or tamoxifen plus ovarian suppression as standard endocrine therapy for premenopausal breast cancer patients with endocrine-resp...
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PMID: 20130426
PDF is available here.
PDF is available here.
Nursing Times (105)22 2009
Abstract
This article is the second in a three-part series discussing the effects of long periods of bedrest on the body. It explores what happens to the gastrointestinal, endocrine and renal systems when a person is confined to bed. The effects on the reproductive and nervous systems are also covered. Part...
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PMID: 19579399
PDF is available here.
PDF is available here.
BioFactors (35)1 2009
Abstract
Endocrine fibroblast growth factors (FGFs) function as hormones that maintain specific metabolic states by controlling homeostasis of bile acid, glucose, fatty acid, phosphate, and vitamin D. Endocrine FGFs exert their biological activity through a common design of coreceptor system consisting of th...
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PMID: 19319846
PDF is available here.
PDF is available here.
Abstract
After statistical analysis of the data a significant decrease of cortisol levels of patients was found, which was not directly correlated with radon concentration. In the case of thyroid hormones, there were no significantly detectable changes of the hormone levels except for low radon concentration...
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PMID: 19296342
PDF is available here.
PDF is available here.
Medical Science Monitor (15)1 2009
Abstract
There is no doubt that the nervous system is involved in the etiopathogenesis of various pathological states and diseases. Interactions between the nervous, endocrine, and immune systems might represent the anatomical and functional basis for understanding the pathways and mechanisms that enable the...
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PMID: 19114982
PDF is available here.
PDF is available here.
BMC Genomics (10)1 2009
Abstract
We have analyzed with microarrays five tissues from the endocrine axis (hypothalamus, adenohypophysis, thyroid gland, gonads and fat tissue) of 16 pigs from both sexes pertaining to four extreme breeds (Duroc, Large White, Iberian and a cross with SinoEuropean hybrid line). Using a Bayesian linear m...
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PMID: 19239697
PDF is available here.
PDF is available here.
Abstract
Phenolic compounds may be of natural or anthropogenic origin and be present in the environment as well as in food. They comprise a large and diverse group of compounds that may be either beneficial or harmful for consumers. In this review first a non-exhausting overview of interesting phenolics is g...
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PMID: 19158655
PDF is available here.
PDF is available here.