Abstract
Over the past 20 years, naturally occurring mutations that affect G protein-coupled receptors (GPCRs) have been identified, mainly in patients with endocrine diseases. The study of loss-of-function or gain-of-function mutations has contributed to our understanding of the pathophysiol...
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PMID: 21301490
PDF is available here.
Abstract
We assessed the prevalence of post-BMT endocrine complications in children treated at the Alberta Children's Hospital (ACH) from 1991 to 2001. Time of onset of endocrine dysfunction, underlying disease processes, chemotherapy, radiation therapy and age at BMT were characterized. Subjects of <18 year...
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PMID: 21823531
PDF is available here.
Abstract
Craniopharyngiomas are the third most common pediatric brain tumor and most common pediatric suprasellar tumor. Contemporary treatment of craniopharyngiomas uses limited surgery and radiation in an effort to minimize morbidity, but the long-term health status of patients treated in this fashion has...
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PMID: 21207770
PDF is available here.
Abstract
To identify the association between medical or psychiatric comorbidities, clinical characteristics, or course of illness/recovery in pediatric bipolar disorder (BD).
Data from the South Carolina Medicaid program covering all medical services and medication prescriptions between January 1996 and Dece...
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PMID: 20584522
PDF is available here.
Abstract
Systemic diseases may affect the oral tissues, i.e. oral mucosa, salivary glands, teeth or bone, and oral manifestations will frequently present early, i.e. in association with (non-fulminant) systemic disease. Thus, recognition and proper diagnosis is essential to initiate appropriate treatment sch...
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PMID: 21044560
PDF is available here.
Abstract
Children who are diagnosed with cancer have a five-year survival rate of nearly 80%, and many live well into adulthood. Because of their disease and treatment exposures, survivors of childhood cancer are at risk for unique long-term health effects. This article reviews some of the more common late e...
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PMID: 21140760
PDF is available here.
Abstract
VTE can be considered as a multicausal disease involving various inherited and acquired prothrombotic conditions. Although greater emphasis has classically been given to traditional thrombophilic risk factors, there is increasing recognition of less typical precipitating conditions and events. In th...
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PMID: 20659655
PDF is available here.
Abstract
We demonstrate strong association between non-DM ESRD in African Americans with MYH9, and have identified additional candidate loci....
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PMID: 20532800
PDF is available here.
Abstract
Hypothyroidism is a common hormonal disorder in women that may affect the phases of female sexual function.
To investigate female sexual function in patients with clinic hypothyroidism and subclinic hypothyroidism.
A total of 25 women with clinic hypot...
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PMID: 20412428
PDF is available here.
Abstract
Hypothyroidism is a common hormonal disorder in women that may affect the phases of female sexual function.
To investigate female sexual function in patients with clinic hypothyroidism and subclinic hypothyroidism.
A total of 25 women with clinic hypot...
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PMID: 20412428
PDF is available here.
Abstract
Hypothyroidism is a common hormonal disorder in women that may affect the phases of female sexual function.
To investigate female sexual function in patients with clinic hypothyroidism and subclinic hypothyroidism.
A total of 25 women with clinic hypot...
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PMID: 20412428
PDF is available here.
Abstract
Hypothyroidism is a common hormonal disorder in women that may affect the phases of female sexual function.
To investigate female sexual function in patients with clinic hypothyroidism and subclinic hypothyroidism.
A total of 25 women with clinic hypot...
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PMID: 20412428
PDF is available here.
Abstract
Hypothyroidism is a common hormonal disorder in women that may affect the phases of female sexual function.
To investigate female sexual function in patients with clinic hypothyroidism and subclinic hypothyroidism.
A total of 25 women with clinic hypot...
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PMID: 20412428
PDF is available here.
Abstract
Hypothyroidism is a common hormonal disorder in women that may affect the phases of female sexual function.
To investigate female sexual function in patients with clinic hypothyroidism and subclinic hypothyroidism.
A total of 25 women with clinic hypot...
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PMID: 20412428
PDF is available here.
Abstract
Hypothyroidism is a common hormonal disorder in women that may affect the phases of female sexual function.
To investigate female sexual function in patients with clinic hypothyroidism and subclinic hypothyroidism.
A total of 25 women with clinic hypot...
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PMID: 20412428
PDF is available here.
Abstract
Hypothyroidism is a common hormonal disorder in women that may affect the phases of female sexual function.
To investigate female sexual function in patients with clinic hypothyroidism and subclinic hypothyroidism.
A total of 25 women with clinic hypot...
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PMID: 20412428
PDF is available here.
Abstract
We observed significant weight changes in ovaries, adrenal glands, thyroid glands, liver, and kidneys; conversely, body weight was not altered following paraben treatment. The potential effects of parabens on estrogenicity were shown in histopathological abnormities in the reproductive organs. Histo...
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PMID: 20132880
PDF is available here.
Abstract
Long-term treatment of chronic pain with strong opioids causes side effects that can be attributed to hormonal abnormalities caused by opioid-induced inhibition of hypothalamic-pituitary function. Hormone substitution can be indicated to treat symptoms. Decreasing the opioid dose or stopping the opi...
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PMID: 20473043
PDF is available here.
Abstract
Secondary osteoporosis is caused by various disorders, metabolic derangements, and drug administration, whose elimination as a cause for osteoporosis is necessary before establishing the diagnosis of primary osteoporosis. The underlying diseases or conditions are diversified, including those related...
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PMID: 20445274
PDF is available here.
Abstract
Testosterone, as the most important sex hormone of the male, plays a critical role in growth, development, reproduction, and maintenance of the functions of vital organs. Testosterone deficiency may lead to functional disorders in many organs or systems, which are collectively termed testosterone de...
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PMID: 20626153
PDF is available here.
Abstract
There is only limited community-based practice safety information available regarding antidepressant use in pediatric patients. This study identifies the factors associated with incident neuroendocrine-related metabolic, digestive, and sexual/reproductive adverse events in children a...
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PMID: 19769598
PDF is available here.
Abstract
Endocrine impairment is more common in patients with diabetes than in general population. Both hyper- and hypothyroidism increases cardiovascular morbidity and mortality. Subclinical hypothyroidism is a risk factor for coronary hearth disease in patients younger than 65 years. In elderly is its infl...
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PMID: 20465095
PDF is available here.
Abstract
A pioneer study has been established in Germany for investigating the frequency of AGS (CAH), PP, PCH, MB, UTS, and GHD among children and adolescents. Our data shows that these disorders occur in approx. 2,700 children per year in total Germany, and about 12 000 of these children need to be treated...
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PMID: 20148377
PDF is available here.
Abstract
There is a long history of hormones altering behavior and endocrinopathies playing a role in psychiatric disease. This article highlights the hormonal changes that occur with aging and the effects of these hormonal changes on the brain, concentrating not on the well-known psychiatric manifestations...
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PMID: 20176293
PDF is available here.
Abstract
Bone age is a measure of developmental age, or physiological maturity, which represents more truthfully than chronological age, how far an individual has progressed towards full maturity. It is particularly helpful in the clinical workup of children with growth and/or puberty disorders as well as in...
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PMID: 20190534
PDF is available here.
Abstract
Therapeutic intervention with 5-HTP, carbidopa and a specific serotonin reuptake inhibitor significantly improved her clinical symptoms and caused biochemical normalisation of neurotransmitters. CONCLUSION: The girl described had the typical symptoms of a hypothalamic disorder and a defective seroto...
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PMID: 20190542
PDF is available here.
Abstract
In this article, we describe the recent studies on pathophysiology of the muscular skeletal complaints in endocrine disease. In addition we report on population as well as genetic studies, which address the relationship between endocrine and rheumatologic disease, both of which are autoimmune. SUMMA...
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PMID: 19935068
PDF is available here.
Abstract
The central neuroendocrine systems are responsible for the control of homeostatic processes in the body, including reproduction, growth, metabolism and energy balance, as well as stress responsiveness. These processes are initiated by signals in the central nervous system, specifically the hypothala...
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PMID: 20363718
PDF is available here.
Abstract
Variation in the normal eruption of teeth is a common finding, but significant deviation from established norms should alert the clinician to take some diagnostic procedures in order to evaluate patient health and development. Disturbance in tooth eruption time could be a symptom of general conditio...
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PMID: 21063135
PDF is available here.
Abstract
We summarize the existing literature data concerning the involvement of skeletal muscle (SM) in whole body glucose homeostasis and the contribution of SM insulin resistance (IR) to the metabolic derangements observed in several endocrine disorders, including polycystic ovary syndrome (PCOS), adrenal...
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PMID: 20300436
PDF is available here.
Abstract
There is a complex interplay between sleep, metabolism and the function of the endocrine system. A number of endocrine systems are modulated by either the homeostatic drive to sleep, or by the function of the circadian system. As a result, changes in sleep duration and quality have reciprocal effect...
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PMID: 20526243
PDF is available here.
Abstract
A total of 1038 Muscovites (740 males and 298 females) aged 20 to 60 years were examined using a broad range of clinical and diagnostic methods. In the study cohort, the prevalence of all diseases taken together was 1533 cases per 1000 examinees, the number of cases being 1108.1 and 2590.6% per hund...
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PMID: 20496492
PDF is available here.
Abstract
Functional ovarian neoplasms have unique clinical manifestations related to hormone overproduction and may give rise to a broad spectrum of clinical syndromes. Sex cord-stromal tumors, the most common functional ovarian neoplasms, are associated with either hyperestrogenism (as in granulosa cell tum...
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PMID: 20631359
PDF is available here.
Abstract
The objective of the present study was to analyse changes of morphological properties in the organs of immune and endocrine systems in subjects with opioid addiction and chronic alcoholic intoxication (CAI) based on the results of 322 autopsies. These included 190 cases of drug addiction from 0.5 to...
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PMID: 20394195
PDF is available here.
Abstract
Eating disorders belong to frequent health problems affecting people in developed countries. They are generally seen in young women and are particularly common in adolescence. Endocrine consequences of these disorders include: excessive activity of hypothalamic-pituitary-adrenal axis, hypogonadotrop...
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PMID: 20941919
PDF is available here.
Abstract
Over a period of two years, 72 adult males with liver cirrhosis of different aetiologies were studied in terms of clinical and biochemical evidence of endocrine dysfunctions related to hypothalamic-pituitary-gonadal axis and the thyroid status, and compared with 40 age-matched control subjects. With...
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PMID: 20509471
PDF is available here.
Abstract
A thorough assessment of a patient's medical status is standard practice when dental care is provided. Although this is true for procedures performed under local anesthesia alone, the information gathered may be viewed somewhat differently if the dentist is planning to provide sedation or general an...
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PMID: 20020794
PDF is available here.
Abstract
We shall try to characterize it and to propose formulas of prediction of the alveolar bone loss according to the age of the patient. We shall expose an analysis of factors bound to the alveolar bone loss and propose a modeling of the alveolar bone loss according to the age in an essentially predicti...
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PMID: 20614694
PDF is available here.
Abstract
More than 80% of children with acute lymphoblastic leukemia can now be cured. Relapses are rare after five years of remission. The most frequent sites of relapse are bone marrow, the central nervous system, and the testicles. Long-term follow-up is needed to detect late adverse effects of treatment....
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PMID: 20669633
PDF is available here.
Abstract
The successful introduction of highly active antiretroviral therapy (HAART), a combination of potent antiretroviral agents, including protease inhibitors, nucleoside reverse transcriptase inhibitors, and nonnucleoside reverse transcriptase inhibitors, has impacted positively on morbidity and mortali...
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PMID: 19355810
PDF is available here.
Abstract
We discuss the current published data on sex differences observed in the occurrence, symptomatology and reporting of the adverse effects associated with psychotropic drug effects, and discuss their clinical relevance. We reviewed the published data up to April 2009 on sex differences in the side eff...
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PMID: 19761372
PDF is available here.
Abstract
Acute and chronic diarrheal disorders are common problems at all ages. It has been estimated that 5% to 7% of the population has an episode of acute diarrhea each year and that 3% to 5% have chronic diarrhea that lasts more than 4 weeks. It is likely that the prevalence of diarrhea is similar in old...
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PMID: 19699409
PDF is available here.
Abstract
Rheumatoid arthritis (RA) in the geriatric population presents a unique challenge to treating clinicians. It can present as preexisting disease that may have been present for years or as a de novo onset of the illness. Diagnosis and management requires a detailed knowledge of the disease, its differ...
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PMID: 20722245
PDF is available here.
Abstract
Increasing data are known for dialogue between neuroendocrine and immune systems recently. Results of molecular genetic studies provided evidences for common languages of these systems by various signals including neurotransmitters, hormones, cytokines. It is proved the immune system is able to prod...
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PMID: 19648077
PDF is available here.
Abstract
Cognitive effects of CRT through 5 years after CRT correlated with patient age, neurofibromatosis type 1 status, tumor location and volume, extent of resection, and radiation dose. The effect of age exceeded that of radiation dose; patients younger than 5 years experienced the greatest decline in co...
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PMID: 19581535
PDF is available here.
Abstract
Fanconi anemia (FA) is a genetically and phenotypically heterogeneous recessive disorder characterized by diverse congenital malformations, progressive pancytopenia, and predisposition to both hematologic malignancies and solid tumors. Congenital anomalies vary from patient to patient and may affect...
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PMID: 19622403
PDF is available here.