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Diabetes Mellitus (6):
Recent article
Diabetes Mellitus
Abstract
We hypothesized that ESRD patients with relative thrombocytosis (platelet count >300 × 10(3)/μL) have a higher mortality rate and that this association may be related to malnutrition-inflammation cachexia syndrome (MICS).
We examined the associations of 3-mo-averaged platelet count...
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PMID: 21813809
PDF is available here.
PDF is available here.
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Abstract
We compared achievement of and improvement in quality standards for diabetes at practices using EHRs with those at practices using paper records. All practices, including many safety-net primary care practices, belonged to a regional quality collaborative and publicly reported performance....
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PMID: 21879900
PDF is available here.
PDF is available here.
Abstract
We conducted a randomized trial involving 150 kidney transplant recipients to compare tacrolimus/sirolimus, tacrolimus/mycophenolate mofetil (MMF), and cyclosporine/sirolimus. All patients received daclizumab induction and maintenance corticosteroids. Median follow-up was 8 yr post-transplant. Acute...
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PMID: 21807891
PDF is available here.
PDF is available here.
Abstract
We report a comprehensive analysis of genotype-dependent metabolic phenotypes using a GWAS with non-targeted metabolomics. We identified 37 genetic loci associated with blood metabolite concentrations, of which 25 show effect sizes that are unusually high for GWAS and account for 10-60% differences...
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PMID: 21886157
PDF is available here.
PDF is available here.
Orvosi Hetilap (152)34 2011
Abstract
Despite advances in the management of cardiovascular diseases, the incidence of cardiovascular diseases is increasing both in developed and developing world. This phenomenon is associated with the worldwide pandemic of obesity and type 2 diabetes; both are related to the life style o...
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PMID: 21835741
PDF is available here.
PDF is available here.
Abstract
This study aimed to examine the participation of Australian Chinese in cardiovascular risk factor and cancer screening.
A telephone survey of a random sample of Chinese in New South Wales, Australia, was conducted. The presence of, and participation in screening for,...
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PMID: 21819359
PDF is available here.
PDF is available here.
Abstract
Diabetes mellitus (DM) is a metabolic disorder caused by insufficient or inefficient insulin secretary response and it is characterized by increased blood glucose levels (hyperglycemia). DM is a heterogonous group of syndromes. Glucose is the main energy source for the body, and in t...
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PMID: 21826590
PDF is available here.
PDF is available here.
Abstract
To assess the prevalence of diabetes and diabetic retinopathy in indigenous Australians aged ≥40 years.
The National Indigenous Eye Health Survey used a stratified, multistage cluster probability sampling frame to provide a representative sample of the indigenous Au...
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PMID: 21819502
PDF is available here.
PDF is available here.
Abstract
The aim of this study was to compare coronary artery plaque burden, composition, distribution, and the degree of coronary artery stenosis in diabetic and nondiabetic patients with known or suspected coronary artery disease (CAD). The study group consisted of 594 patients with known o...
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PMID: 21741605
PDF is available here.
PDF is available here.
Abstract
Abstract
Diabetes mellitus is a complex metabolic disorder characterized by chronic hyperglycemia and vascular complications, leading to significant morbidity and mortality. All forms of diabetes are ultimately related to insufficient functional pancreatic β-cell mass to maintain euglycemia....
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PMID: 21644916
PDF is available here.
PDF is available here.
Abstract
Our results indicate that the stability of the complexes between W and proteins is not too high enough to remain unaltered during protein separation by SDS-PAGE in denaturing and reducing conditions. However, the procedures for in-solution tryptic digestion and for ESI-MS analysis in MeOH/H(2)O/with...
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PMID: 21530773
PDF is available here.
PDF is available here.
Abstract
This exploratory study set out to identify how communities in the Tufts University Clinical Translational Science Institute (CTSI) catchment area define health-related research priority areas.
Three focus groups comprising community stakeholders were conducted in thre...
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PMID: 21707945
PDF is available here.
PDF is available here.
Abstract
The person with diabetes have a number of tensions that may precipitate a psychological disorder. All studies in this regard indicate that the most prevalent are anxiety and depression. Nursing consultation is in a prime location for early detection to facilitate their treatment. So...
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PMID: 21830366
PDF is available here.
PDF is available here.
Transplantation (91)9 2011
Abstract
Cardiovascular disease, the most common cause of death with a functioning graft among kidney transplant recipients, can be exacerbated by immunosuppressive drugs, particularly the calcineurin inhibitors. Belatacept, a selective co-stimulation blocker, may provide a better cardiovascu...
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PMID: 21372756
PDF is available here.
PDF is available here.
MMW Fortschritte der Medizin (153)19 2011
Abstract
Abstract
GPR40, a G-protein-coupled receptor has been well established to play a crucial role in regulating blood glucose levels. Hence, GPR40 is a potential target for future antidiabetic agents. The present 3D QSAR study is aimed at delineating structural parameters governing GPR40 agonisti...
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PMID: 21352503
PDF is available here.
PDF is available here.
Abstract
An alert system in a hospital information system (HIS) would be helpful for physicians to prescribe medication appropriately. In this study we developed an alert system that extracts target problems from the raw data and verifies whether contraindicated medication is prescribed.
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PMID: 21706868
PDF is available here.
PDF is available here.
Abstract
Patients with diabetes have increased in-hospital mortality following acute myocardial infarction (AMI), with studies suggesting higher risk with both hypoglycemia and hyperglycemia. We assessed whether a J-shaped relation exists between hemoglobin A1c (A1C) in patients with diabetes and AMI.
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PMID: 21473963
PDF is available here.
PDF is available here.
Abstract
Abstract
We offer a theory to predict reversibility of diabetes after bariatric surgery that is based on baseline beta cell function.
This review will improve the understanding of the physiology of bariatric surgery and its impact on T2DM, stimulate investigations into new avenues to treat T2...
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PMID: 21522001
PDF is available here.
PDF is available here.
Proteomics (11)7 2011
Abstract
We established a 2-DE reference map for INS-1E cells. Using MALDI-TOF/TOF-MS/MS, we identified 546 spots. These included various proteins with an important role in β-cell physiology and with known roles as crucial proteins for diabetes development. We believe that the availability of this reference...
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PMID: 21365744
PDF is available here.
PDF is available here.
Journal of Pediatrics (158)4 2011
Abstract
Our findings indicate that hyperglycemia and DM can occur with pancreatitis. In some cases, postpancreatitis DM was associated with mental retardation, seizure disorder, and use of antiseizure medication. As opposed to adults who develop DM after chronic pancreatitis, children can develop DM due to...
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PMID: 21093873
PDF is available here.
PDF is available here.
Abstract
Acta Physiologica (201)3 2011
Abstract
We specifically focus in this review on the impact of those adipocytokines on the modulation of insulin action in skeletal muscle.
© 2011 The Author. Acta Physiologica © 2011 Scandinavian Physiological Society....
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PMID: 21040498
PDF is available here.
PDF is available here.
Abstract
The purpose of the study was to assess the presence and extent of atherosclerosis determined by 64-slice CTA in patients with 0 coronary calcium score (CACS) and to evaluate the affect of demographic features and risk factors on the atheroma burden of these patients. 883 cases (378 (...
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PMID: 20734235
PDF is available here.
PDF is available here.
Abstract
Interleukin-25 (IL-25) plays a key role in the initiation and expansion of T helper (Th) 2 cell-mediated immune responses, thereby contributing to allergic diseases and host defense against helminthic parasites. More recent studies have however shown that IL-25 can also control the f...
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PMID: 21189120
PDF is available here.
PDF is available here.
Abstract
Abstract
the evidence from epidemiologic, clinical, and mechanistic studies is consistent in finding that the risk of CHD is reduced when SFAs are replaced with polyunsaturated fatty acids (PUFAs). In populations who consume a Western diet, the replacement of 1% of energy from SFAs with PUFAs lowers LDL chol...
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PMID: 21270379
PDF is available here.
PDF is available here.
Abstract
We hypothesized that individual exposure to particulate matter (PM) derived from fossil fuel would correlate with plasma concentrations of oxidized low-density lipoprotein (LDL), taken as a marker of atherosclerosis. We tested this hypothesis in patients with diabetes, who are at high risk for ather...
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PMID: 21283820
PDF is available here.
PDF is available here.
Abstract
Hypertension frequently coexists with diabetes and the cardiometabolic syndrome. β-Blockers have been a mainstay for controlling blood pressure for nearly 4 decades. However, β-blockers are perceived to cause glucose and lipid metabolism dysregulation, including hypoglycemia masking, reduced glycem...
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PMID: 21214722
PDF is available here.
PDF is available here.
Abstract
A 74-year-old woman with impaired glucose tolerance exhibited virilization. An examination of various hormone levels showed normal pituitary hormone and adrenal hormone levels. However, the patient's blood testosterone level was remarkably high and was suspected of having caused the virilization. An...
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PMID: 20924286
PDF is available here.
PDF is available here.
Abstract
We have been investigating the efficacy of various modalities of blood purification therapy by continuously monitoring changes of tissue blood flow in the lower limbs and earlobes (head) using non-invasive continuous monitoring method (NICOMM). In this report, we assess the clinical effectiveness of...
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PMID: 20938141
PDF is available here.
PDF is available here.
Epigenetics (6)1 2011
Abstract
We identified potential epigenetic biomarkers for chronic kidney disease progression by comparing site-specific DNA methylation levels in more than 14,000 genes between African American and Hispanic diabetes patients with end stage renal disease (ESRD) and diabetes patients without nephropathy. We i...
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PMID: 21150313
PDF is available here.
PDF is available here.
Epigenetics (6)1 2011
Abstract
We identified potential epigenetic biomarkers for chronic kidney disease progression by comparing site-specific DNA methylation levels in more than 14,000 genes between African American and Hispanic diabetes patients with end stage renal disease (ESRD) and diabetes patients without nephropathy. We i...
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PMID: 21150313
PDF is available here.
PDF is available here.
Abstract
Persistently elevated oxidative stress and inflammation precede or occur during the development of type 1 or type 2 diabetes mellitus and precipitate devastating complications. Given the rapidly increasing incidence of diabetes mellitus and obesity in the space of a few decades, new...
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PMID: 21610689
PDF is available here.
PDF is available here.
Abstract
Recent advances in pancreas organogenesis have greatly improved the understanding of cell lineage from inner cell mass to fully differentiated β-cells. Based upon such knowledge, insulin-producing cells similar to β-cells to a certain extent have been generated from various cell so...
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PMID: 20589399
PDF is available here.
PDF is available here.
Medical Care (49)1 2011
Abstract
Professional and patient groups have called for increased participation of patients' informal support networks in chronic disease care, as a means to improve clinical care and self-management. Little is known about the current level of participation of family and friends in the physician visits of a...
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PMID: 21102357
PDF is available here.
PDF is available here.
Abstract
We assessed the prevalence of post-BMT endocrine complications in children treated at the Alberta Children's Hospital (ACH) from 1991 to 2001. Time of onset of endocrine dysfunction, underlying disease processes, chemotherapy, radiation therapy and age at BMT were characterized. Subjects of <18 year...
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PMID: 21823531
PDF is available here.
PDF is available here.
Critical Care Medicine (39)1 2011
Abstract
Critical Care Medicine (39)1 2011
Abstract
We tested whether the degree of preexisting hyperglycemia would modulate the association between glycemia and outcome during critical illness in patients with diabetes mellitus.
Retrospective observational study.
Two tertiary intensive care units.
Four hundred fifteen critically ill diabetic patient...
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PMID: 20975552
PDF is available here.
PDF is available here.
West Indian Medical Journal (60 Suppl 1) 2011
Abstract
British Journal of Nutrition (105)1 2011
Abstract
The objective of the present study was to compare whole pea flour (WPF) to fractionated pea flour (FPF; hulls only) for their ability to reduce risk factors associated with CVD and diabetes in overweight hypercholesterolaemic individuals. Using a cross-over design, twenty-three hypercholesterolaemic...
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PMID: 20807459
PDF is available here.
PDF is available here.
Abstract
We report the first results of a pilot trial aiming to test the feasibility and safety of this technique in humans.
Islets were labeled in culture with 5 μL/mL ferucarbotran for 6 to 48 hr and transplanted into the portal vein (12 infusions) in 8 C-peptide negative recipients. The liver area was ex...
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PMID: 21197715
PDF is available here.
PDF is available here.
Journal of Biological Chemistry (285)52 2010
Abstract
We examined aspects of the Igf1r regulatory signaling cascade in β cells. To examine genetically the involvement of Irs1 and Irs2 in Igf1r signaling, we generated double mutant mice lacking Igf1r specifically in pancreatic β cells in an Irs1- or Irs2-null background. We show that Igf1r/Irs1 double...
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PMID: 20947509
PDF is available here.
PDF is available here.
Abstract
We analyzed the clinical and electrophysiologic characteristics in, and the clinical outcome of, patients with AF with and without an abnormal glucose metabolism. The right atrial (107.2 ± 15.4 vs 96.0 ± 16.5 ms, p < 0.001) and left atrial (108.4 ± 22.3 vs 94.0 ± 17.5 ms, p < 0.001) total activa...
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PMID: 21094363
PDF is available here.
PDF is available here.
Journal of Glaucoma (19)9 2010
Abstract
We found that the central cornea of diabetic patients is thicker when compared with nondiabetic patients. Thicker central cornea associated with diabetes mellitus should be taken into consideration while obtaining accurate intraocular pressure measurements in diabetics....
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PMID: 20051882
PDF is available here.
PDF is available here.
Abstract
We used a protocol based on dynamic insulin administration targeted to achieve moderately tight glycemic control and tested its impact on clinical outcomes after cardiac surgery.
Patients with diabetes mellitus or random blood glucose greater than 150 mg/dL were treated in the intensive care unit wi...
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PMID: 21095319
PDF is available here.
PDF is available here.
Medical Care (48)12 2010
Abstract
We link patients to their principal ambulatory care physician. The patients are then linked to the hospital where their physicians work or have their patients admitted, creating physician-hospital networks.
Proportion of recommended diabetes testing received by black and nonblack diabetes patients....
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PMID: 21063231
PDF is available here.
PDF is available here.
Abstract
British Journal of Nutrition (104)12 2010
Abstract
MMW Fortschritte der Medizin (152)44 2010
Abstract
Abstract
We hypothesized these behaviors would predispose FI adults with diabetes to hypoglycemia and impaired diabetes self-management. We therefore assessed whether food insecurity was associated with multiple indicators of diabetes self-management (self-efficacy, medication- and glucose-monitoring adheren...
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PMID: 21099074
PDF is available here.
PDF is available here.
Abstract
Despite the large disease burden of diabetes, little is known about the care experiences of Latinos with diabetes across diverse primary care settings. This study compares problematic care experiences among Latinos with diabetes across usual care sites (community health centers [CHCs], private physi...
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PMID: 21099068
PDF is available here.
PDF is available here.
Clinical calcium (20)11 2010
Abstract
The cohort studies reported the subclinical vascular calcification including atheroslerosis starts during prediabetic state characterized by impaired fasting glucose. In the cardiovascular systems of diabetes mellitus there is an original mechanism to induce the medial calcification other than intim...
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PMID: 21037381
PDF is available here.
PDF is available here.
Abstract
We review the literature describing the effect of lipid-lowering agents on adiponectin bioavailability. Statins exert variable effects that can be influenced by patient-dependent characteristics (i.e. diabetes or insulin resistance). Fibrates and especially niacin can raise adiponectin levels. The i...
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PMID: 20180775
PDF is available here.
PDF is available here.
Abstract
The pen injection format, typically used for insulin administration, has been adapted for the injectable, noninsulin diabetes therapy pramlintide. Administered before major meals, pramlintide therapy requires two to four injections/day in addition to the patients' usual insulin injec...
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PMID: 21129339
PDF is available here.
PDF is available here.
Abstract
This study deals with the effects of daily intermittent fasting for 15 h upon the development of diabetes in sand rats exposed to a hypercaloric diet. The same pattern of daily intermittent fasting was imposed on sand rats maintained on a purely vegetal diet (control animals). Over the last 30 days...
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PMID: 20878099
PDF is available here.
PDF is available here.
Revue de l'infirmiere ()165 2010
Abstract
Diabetes forecast (63)11 2010
Abstract