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Welcome to the Pubget Medical Subject Headings (MESH) browser. Click on a topic or subtopic below to explore related papers. In the gold box is the most recent paper about the current MESH term, and below are 20 related papers.
Enzymes and Coenzymes (4):
Recent article
Enzymes and Coenzymes
Experimental Dermatology (12)4 2003
Abstract
We performed a detailed kinetic study to clarify the mechanism of androgen action on sebaceous gland function. We demonstrated that the growth of sebaceous glands observed after androgen treatment was due to both an increase in sebocyte proliferation and a parallel induction of sebocyte terminal dif...
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PMID: 12930306
PDF is available here.
PDF is available here.
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Protein Science (12)7 2003
Abstract
We utilize the same approach to investigate the possibility of a similar interaction in pyruvate formate-lyase activating enzyme (PFL-AE) and biotin synthase (BioB), two additional members of the radical-SAM superfamily. The results show that the latter two enzymes do not exhibit the same Fe-Se inte...
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PMID: 12824504
PDF is available here.
PDF is available here.
Abstract
The methyl esters of carboxylic acids are characteristic olfactory volatile compounds for the sweet aroma of snake fruit, (Salacca edulis, Reinw) cv. Pondoh. Although methanol was not detected as a volatile constituent, the crude enzymes showed activity to synthesize the methyl esters in the presenc...
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PMID: 12843652
PDF is available here.
PDF is available here.
Chemical Reviews (103)6 2003
Abstract
Plant Physiology (132)2 2003
Abstract
We examined transcriptional changes that occur during systemic defense responses in Arabidopsis plants inoculated with the incompatible fungal pathogen Alternaria brassicicola. Substantial changes (2.00-fold and statistically significant) were demonstrated in distal tissue of inoculated plants for 3...
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PMID: 12805628
PDF is available here.
PDF is available here.
Acta Crystallographica Section D (59)Pt 2 2003
Abstract
A program, Hess2FF, has been developed that automatically constructs parameter and topology files to be used in crystallographic refinement for any molecule, based on a Hessian (force-constant) matrix estimated by any method. The program is tested by redefining hetero-compounds in five different pro...
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PMID: 12554938
PDF is available here.
PDF is available here.
Abstract
Genome analyses and the resolution of three-dimensional structures have provided evidence in recent years for hitherto unexpected family relationships between redox proteins of very diverse enzymes involved in bioenergetic electron transport. Many of these enzymes appear in fact to be constructed fr...
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PMID: 12594934
PDF is available here.
PDF is available here.
Abstract
The potential energy surface of the free 5'-deoxyadenosyl radical in the gas phase is explored using density functional and second-order Møller-Plesset perturbation theories with 6-31G(d) and 6-31++G(d,p) basis sets and interpreted in terms of attractive and repulsive interactions. The 5',8-cycliza...
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PMID: 12517173
PDF is available here.
PDF is available here.
Abstract
These results indicate that robinia and oleander have a pathway that produces sinapyl alcohol from sinapic acid via sinapoyl-CoA. By contrast, in magnolia and Arabidopsis, 4CL activity toward sinapic acid could not be detected, and labeled sinapic acid was not incorporated into lignin. These results...
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PMID: 12520342
PDF is available here.
PDF is available here.
Abstract
The structural analysis of all enzymes in a metabolic pathway is a prerequisite to answering fascinating questions, such as those relating to the evolutionary relationships between enzymes within the same and related pathways. Furthermore, the observed impressive diversity of catalytic functions dis...
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PMID: 12504674
PDF is available here.
PDF is available here.
Journal of Experimental Botany (53)375 2002
Abstract
The transition element molybdenum (Mo) is essential for (nearly) all organisms and occurs in more than 40 enzymes catalysing diverse redox reactions, however, only four of them have been found in plants. (1) Nitrate reductase catalyses the key step in inorganic nitrogen assimilation, (2) aldehyde ox...
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PMID: 12147719
PDF is available here.
PDF is available here.
Abstract
As many as one-third of mutations in a gene result in the corresponding enzyme having an increased Michaelis constant, or K(m), (decreased binding affinity) for a coenzyme, resulting in a lower rate of reaction. About 50 human genetic dis-eases due to defective enzymes can be remedied or ameliorated...
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PMID: 11916749
PDF is available here.
PDF is available here.
Biochimica et Biophysica Acta (1595)1-2 2002
Abstract
These results demonstrate that a small alteration of local structure by ligand binding and mutation is dramatically magnified in the flexibility of protein molecule to affect the function. Compressibility gives new insight into protein dynamics and enzyme function from the aspect of atomic packing o...
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PMID: 11983410
PDF is available here.
PDF is available here.
Journal of Bacteriology (183)24 2001
Abstract
We have named fbiA and fbiB for F(420) biosynthesis. Homologues of fbiA were found in all seven microorganisms that have been fully sequenced and annotated and that are known to make F(420). fbiB homologues were found in all but one such organism. Complementation of the fbiA mutant with fbiAB and co...
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PMID: 11717263
PDF is available here.
PDF is available here.
Trends in Biotechnology (19)12 2001
Abstract
Escherichia coli has been a popular organism for studying metabolic pathways. In an attempt to find out more about how these pathways are constructed, the enzymes were analysed by defining their protein domains. Structural assignments and sequence comparisons were used to show that 213 domain famili...
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PMID: 11711174
PDF is available here.
PDF is available here.
Chemical Reviews (101)10 2001
Abstract
Natural Product Reports (18)5 2001
Abstract
Inorganic Chemistry (40)18 2001
Abstract
We have studied the interactions of Cu(2+) ions with 2-(alpha-hydroxyethyl)thiamin pyrophosphate (HETPP), the pentapeptide Asp-Asp-Asn-Lys-Ile surrounding the thiamin pyrophosphate moiety in the transketolase enzyme, and the tertiary Cu(2+)-pentapeptide-HETPP system in aqueous solutions at various p...
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PMID: 11511203
PDF is available here.
PDF is available here.
Abstract
We have established previously that a heterogeneous population of mRNAs and biologically active polyribosomes exist in the giant axon and presynaptic nerve terminals of the photoreceptor neurons in squid. We report that these mRNA populations contain mRNAs for nuclear-encoded mitochondrial proteins...
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PMID: 11391699
PDF is available here.
PDF is available here.
FEBS Letters (495)1-2 2001
Abstract
Over the last years, significant progress has been made in the understanding of the genetics and enzymology of the biosynthetic pathway of the vitamin biotin. The enzymes catalyzing the last four steps of this pathway, from pimeloyl-CoA to biotin, provide an ensemble of intriguing reaction mechanism...
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PMID: 11322938
PDF is available here.
PDF is available here.
Abstract
The technology for fluorescence protein-sensing is advancing rapidly owing to the continued introduction of new concepts, new fluorophores, and proteins engineered for sensing-specific analytes. Concerns about the reversibility and selectivity of engineered proteins are being addressed by developing...
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PMID: 11167081
PDF is available here.
PDF is available here.
Abstract
New catalytic synthetic methods in organic chemistry that satisfy increasingly stringent environmental constraints are in great demand by the pharmaceutical and chemical industries. In addition, novel catalytic procedures are necessary to produce the emerging classes of organic compounds that are be...
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PMID: 11196651
PDF is available here.
PDF is available here.
Abstract
We investigated whether differentiation-evoked changes in acetyl-CoA and acetylcholine metabolism contribute to the susceptibility of cholinergic neuroblastoma to cytotoxic effects of Al. In SN56 cells differentiated with retinoic acid and dibutyryl cAMP (DC), pyruvate utilization and acetyl-CoA con...
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PMID: 11070506
PDF is available here.
PDF is available here.
Journal of Bacteriology (182)17 2000
Abstract
Metabolic pathways involved in the formation of cytotoxic end products by Porphyromonas gingivalis were studied. The washed cells of P. gingivalis ATCC 33277 utilized peptides but not single amino acids. Since glutamate and aspartate moieties in the peptides were consumed most intensively, a dipepti...
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PMID: 10940008
PDF is available here.
PDF is available here.