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Oxygenators (1):
Recent article
Oxygenators
Abstract
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Abstract
We revised all of our set up protocols and the recommended actions from manufacturers. We further report three separate incidents of pump boot disconnection from the venous reservoir outlet of the oxygenator during bypass (that occurred within a 13-month period), and an outline of immediate and pros...
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PMID: 20648902
PDF is available here.
PDF is available here.
Abstract
Gaseous microemboli (GME) remain a challenge for cardiopulmonary bypass procedures in adult as well as pediatric cardiac surgery patients. The present study tested the effectiveness of a new adult membrane oxygenator in models both with and without an integrated arterial filter to evaluate GME trapp...
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PMID: 20648898
PDF is available here.
PDF is available here.
Abstract
Adult and pediatric extracorporeal life support (ECLS) has been transformed by the European(1) and Australian( 2) experiences with a reduction of the circuit to its most basic form (Figure 1). Many factors have converged at this point in time to allow us to offer this support. The av...
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PMID: 20172901
PDF is available here.
PDF is available here.
Pediatric Research (66)6 2009
Abstract
Respiratory failure is a major contributor to mortality and morbidity in newborn infants. The lung assist device (LAD) is a novel gas exchange device that supplements mechanical ventilation. The objective is to test the effect of the LAD on pulmonary histopathology in juvenile piglets with acute lun...
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PMID: 19687779
PDF is available here.
PDF is available here.
Pediatric Research (66)6 2009
Abstract
Persistent pulmonary hypertension is an important cause of mortality and morbidity in term infants. The lung assist device (LAD) is a novel, pumpless, low-resistance extracorporeal oxygenator to supplement mechanical ventilation. The LAD may be associated with fewer complications compared with conve...
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PMID: 19687777
PDF is available here.
PDF is available here.
Abstract
We evaluated the ability of the Quadrox-D (Maquet) to effectively remove the electrostatic charge accumulation, with and without a heater/cooler connection (H/C). A Quadrox-D oxygenator was evaluated using a Stockert SIII pump head, Cincinnati subzero H/E, and a custom adult extracorporeal membrane...
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PMID: 19681309
PDF is available here.
PDF is available here.
Abstract
Extracorporeal life support (ECLS) is a procedure used to support the failing heart and/or lungs via a heart lung machine. Over 145 institutions perform this practice in the United States with more than 24,000 ECLS cases recorded. While many articles are published each year on common perfusion pract...
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PMID: 19681303
PDF is available here.
PDF is available here.
Abstract
Abstract
Abstract
We report on the first use of the Terumo CAPIOX FX05 (Baby-FX) oxygenator with integral arterial filter, prime volume 43 ml, evaluating performance and air-handling of six Baby-FX versus thirteen Baby-RX oxygenators. The Terumo Baby-FX primes and performs as easily as the Baby-RX series. A significa...
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PMID: 19654153
PDF is available here.
PDF is available here.
Annals of Internal Medicine (149)12 2008
Abstract
The train from Golmud in Qinghai Province, China, to Lhasa, Tibet, travels for more than 14 hours at an average altitude of 4500 m, the highest point being 5072 m (16,600 ft). Therefore, passengers are potentially exposed to very severe sustained hypoxia. The enterprising solution is to increase the...
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PMID: 19075209
PDF is available here.
PDF is available here.
Abstract
Hemolysis is a fact in all extracorporeal circuits, as shown in various studies by the increasing levels of plasma-free hemoglobin (PfHb) and decreasing levels of haptoglobin during and after cardiopulmonary bypass (CPB). Beside complete red blood cell (RBC) destruction or hemolysis, RBCs can also b...
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PMID: 19192755
PDF is available here.
PDF is available here.
Abstract
The data obtained with this case encourage further research into PAL systems, which may hopefully serve as a bridge to lung transplant device in appropriate patients in the future....
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PMID: 18355495
PDF is available here.
PDF is available here.
ASAIO Journal (54)1 2008
Abstract
We reviewed our experience with a new PMP oxygenator (Quadrox D) and a centrifugal pump (RotaFlow) used to support adult patients with refractory cardiogenic shock. Between January 2000 and April 2007, 25 patients required ECMO for primary or postcardiotomy cardiogenic shock. Eighteen patients were...
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PMID: 18204321
PDF is available here.
PDF is available here.
Artificial Organs (32)1 2008
Abstract
We showed the new design of a blood oxygenator with direct blood-gas contact in an open circuit, specially designed for rats in which the blood oxygenation takes place in a slowly rotating plastic tube with blood spread onto its inner walls in a thin layer. The oxygenator is simple and efficient, do...
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PMID: 18181805
PDF is available here.
PDF is available here.
AADE editors' journal (57)4 2008
Abstract
Premature infants were 13 times more likely to develop NEC if the infant required increased respiratory support to maintain oxygenation during the early neonatal period and 6.4 times more likely to develop NEC if the infant did not receive nutritionally fortified enteral feedings of breast milk. Whe...
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PMID: 18641495
PDF is available here.
PDF is available here.
Abstract
In August 2006, Duke University Perfusion Services had the opportunity to be the first institution in the United States to clinically evaluate the Dideco D100 Neonatal Oxygenator. The device was used on six pediatric patients to facilitate correction or palliation of their cardiac defects, which inc...
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PMID: 18788216
PDF is available here.
PDF is available here.
Abstract
A 50-year-old female underwent surgery for removal of a massive retroperitoneal sarcoma (RPS) involving the right hepatic lobe and the inferior vena cava (IVC), abdominal aorta, right lung, right hemi-diaphragm and pericardium. Resection of the RPS necessitated cross-clamping of the abdominal aorta,...
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PMID: 18788220
PDF is available here.
PDF is available here.
Abstract
We describe an innovative, simple technique of blood conservation for adult patients of tetralogy of Fallot with severely raised hemoglobin. With this technique, hemoglobin can be normalized on CPB; moreover, there is no fear of hypoxemic spell or hemodynamic instability. Furthermore, the blood cons...
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PMID: 18293813
PDF is available here.
PDF is available here.
Abstract
We describe a high-fidelity perfusion simulation system intended for use in the training and continuing education of perfusionists. The system comprises a hydraulic simulator, an electronic interface unit and a controlling computer with associated real-time computer models. It is designed for use wi...
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PMID: 18293807
PDF is available here.
PDF is available here.
Abstract
We present a newborn in whom an ECS was established with the oxygenator used for the surgical correction....
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PMID: 18666738
PDF is available here.
PDF is available here.
Ambulatory oxygenator right ventricular assist device for total right heart and respiratory support.
Abstract
Our ambulatory OxyRVAD can provide total assistance for the right heart and lungs in normal awake sheep for 14 days....
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PMID: 17954089
PDF is available here.
PDF is available here.
Abstract
We present an oxygenation failure with root cause analysis that prompted a new oxygenation safety algorithm and multi-service training initiative....
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PMID: 17972454
PDF is available here.
PDF is available here.
Abstract
Journal of Cardiology (49)2 2007
Abstract
The price disparities for cardiovascular devices between Japan and the US were reconfirmed. Japan's healthcare system should establish group-purchasing organizations, promote centers of clinical excellence, and abolish regulation of parallel imports and protectionism under the Japanese Pharmaceutica...
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PMID: 17354581
PDF is available here.
PDF is available here.
Abstract
Except for a somewhat higher platelet count during CPB, there was no indication that PMEA coating resulted in less activation of coagulation and fibrinolytic systems. The lower postoperative chest tube output observed after CPB with PMEA-coated oxygenators needs to be studied further....
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PMID: 17289476
PDF is available here.
PDF is available here.
Abstract
This article describes recent progress in the field of artificial lungs, centering on the current state and trends in clinical use and research and development. Trends in the recent clinical use in Japan can be found in shipment-number-based surveys as well as in the questionnaire surveys for clinic...
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PMID: 17380289
PDF is available here.
PDF is available here.
ASAIO Journal (53)4 2007
Abstract
We substituted autologous lung for the artificial oxygenator to assess reduction of lung injury after conventional cardiopulmonary bypass (CPB). Twelve piglets were randomly divided into two groups. Experimental animals (n = 6) underwent bilateral CPB with autologous lungs perfusion, whereas control...
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PMID: 17667230
PDF is available here.
PDF is available here.
Abstract
Mean dark-adapted b-wave amplitudes of operated eye/nonoperated eye ratios +/- SD for BSS-plus and BSS-plus + O2 before surgery and 1 hour, 1 day, 1 week, and 1 month after surgery were 1.01 +/- 0.09, 0.50 +/- 0.11, 0.95 +/- 0.11, 0.97 +/- 0.11, and 0.99 +/- 0.08 and 0.98 +/- 0.08, 0.59 +/- 0.10, 0....
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PMID: 17218921
PDF is available here.
PDF is available here.
Abstract
Abstract
Abstract
In comparison with the original BSS, there was an increase in oxygen saturation of 162 +/- 47% (n = 40; P < 0.05). Without oxygenation perfusion, there was only a 24 +/- 14% (n = 40) increase in oxygen levels in BSS, which was significantly lower than that in treated BSS (P < 0.05). In comparison wi...
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PMID: 17218920
PDF is available here.
PDF is available here.
Abstract
The extracardiac conduit Fontan operation coupled with minimal use of extracorporeal circulation is associated with favorable intraoperative hemodynamics, low fenestration rate, minimal risk of thrombosis or stenosis, and minimal early and late rhythm disturbance....
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PMID: 17059923
PDF is available here.
PDF is available here.
Anaesthesia (61)10 2006
Abstract
Extracorporeal oxygenators are artificial devices that substitute for anatomical lungs by delivering oxygen to, and extracting carbon dioxide from, blood. They were first conceptualised by the English scientist Robert Hooke (1635-1703) and developed into practical extracorporeal oxygenators by Frenc...
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PMID: 16978315
PDF is available here.
PDF is available here.
Abstract
Neurologic impairment is a common complication of adult cardiac surgery. Cerebral gaseous microemboli (GME) detected during cardiopulmonary bypass has been associated with cognitive impairment after adult cardiac surgery. Several previous studies have shown that components comprising the extracorpor...
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PMID: 17089505
PDF is available here.
PDF is available here.
Abstract
We present a new oxygenator that can be used in cardiopulmonary bypass experiments in rats, simple in design and efficient in function,in which the process of blood oxygenation takes place in a vertical cylinder filled up with air or oxygen, with blood being spread onto the wall and then trickling d...
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PMID: 16969752
PDF is available here.
PDF is available here.
Artificial Organs (30)7 2006
Abstract
We have made our own heart-lung machine, mechanical and tissue valves, oxygenators, and artificial hearts and their improved versions. The cost of these parts is much lower as compared with those in the Western market. Although the results of clinical application are good so far, the quality of thes...
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PMID: 16836731
PDF is available here.
PDF is available here.
Abstract
The Trillium coating is designed to minimize adsorption of protein and the attachment of cells and other particles. The present study was undertaken to investigate the effect of surface coating on the adhesion of thrombotic components (activated platelets, white blood cells and fibrin) to the surfac...
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PMID: 16817289
PDF is available here.
PDF is available here.
Abstract
Abstract
The present study comparatively analyzed the clinical effects of three solutions used to fill an extracorporeal circulatory circuit (ECCC). The arterial and venous blood samples taken from patients operated on for valvular disease and coronary heart disease were studied. All patients (n = 61) were d...
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PMID: 16889212
PDF is available here.
PDF is available here.
Abstract
These results suggest that oxygenator exhaust capnography is a simple, inexpensive and reliable method of estimating the PaCO2 in both adult and pediatric patients at all relevant-temperatures....
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PMID: 16485695
PDF is available here.
PDF is available here.
Abstract
We have compared the two membrane oxygenators and pump systems used for paediatric bypass at the Royal Children's Hospital on a regular basis since 1988. We looked at all patients who had the Cobe VPCML (Cobe Laboratories, Denver, CO, USA) and Terumo RX-05 (Terumo Corporation, Tokyo, Japan) oxygenat...
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PMID: 16485698
PDF is available here.
PDF is available here.
Abstract
We hypothesized that the use of modern extracorporeal equipment and the involvement of perfusionists in ECMO patient care is largely underreported in previous studies. To study this hypothesis, we developed a standard survey instrument and queried perfusion teams from the hospitals listed on the Ame...
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PMID: 16524150
PDF is available here.
PDF is available here.
Abstract
During cardiopulmonary bypass, the rates of cooling and rewarming and the maximum temperatures attained are implicated in patient morbidity. Thus, accurate oxygenator arterial outlet temperature measurements are needed. The purpose of this study was to determine the accuracy of the arterial outlet t...
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PMID: 16117461
PDF is available here.
PDF is available here.
Abstract
Continuous monitoring and control of arterial carbon dioxide tension (P(a)CO2) during cardiopulmonary bypass (CPB) is essential. A reliable, accurate, and inexpensive system is not currently available. This study was undertaken to assess whether the continuous monitoring of oxygenator exhaust carbon...
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PMID: 16117458
PDF is available here.
PDF is available here.
Abstract
We did a prospective, randomized clinical trial of 54 Synthesis coated oxygenators and compared them with 54 uncoated Monolyth Pro oxygenators, the latter of which incorporated an external arterial line filter with a standard bypass loop There were few statistically significant differences found bet...
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PMID: 16117460
PDF is available here.
PDF is available here.
Laryngoscope (115)4 2005
Abstract
Ex vivo reperfusion offers a range of experimental advantages over in vivo reperfusion including close control of interventions, ease of outcome measurement, and reduction in animal use. This model is now ready to be used for further studies of interventions to reduce ischemia-reperfusion injury in...
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PMID: 15805884
PDF is available here.
PDF is available here.
Abstract
Nitric oxide plus iloprost reduced the deleterious effects of cardiopulmonary bypass, such as thrombocytopenia, platelet activation, platelet-leukocyte aggregate formation, and suppression of platelet aggregative responses. The reduced postoperative bleeding observed with this treatment suggests tha...
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PMID: 15821644
PDF is available here.
PDF is available here.
Panminerva Medica (47)1 2005
Abstract
Over the last years, several observational studies have suggested that extracorporeal lung assist (ECLA) may be an important contribution to clinical algorithms for the treatment of most severe acute respiratory distress syndrome (ARDS). Today ECLA is used only as a rescue therapy in life threatenin...
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PMID: 15985973
PDF is available here.
PDF is available here.
Abstract
A recently published review on a single-center experience in 255 adult ECMO patients identified using multivariate logistic regression analysis age, sex, initial pH 7.10 or lower and PaO2/FiO2 ratio, and days of mechanical ventilation before ECMO as a significant predictors of survival. Additionally...
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PMID: 15659951
PDF is available here.
PDF is available here.
Abstract
Transplant International (17)11 2005
Abstract
The aim of this study was to determine the potential benefit of aerobic machine preservation (MP) with non-colloidal histidine-tryptophan-ketoglutarate (HTK) solution compared with MP with Belzer machine perfusion solution (MPS) and standard cold storage, after marginal kidneys had been obtained fro...
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PMID: 15717215
PDF is available here.
PDF is available here.
ASAIO Journal (51)5 2005
Abstract
Abstract
We developed a system to measure nitric oxide (NO) concentration during cardiopulmonary bypass in anaesthetized pigs (n = 6). A T-shaped connector, attached to an NO sensor, was mounted in the extracorporeal circuit at two measuring sites: proximal to the membrane oxygenator (venous side) and distal...
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PMID: 15938590
PDF is available here.
PDF is available here.
Abstract
Anaesthesia (59)12 2004
Abstract
Critical Care Medicine (32)10 2004
Abstract
These data demonstrate the ability of this novel single-piston, nonporous hollow silicone fiber oxygenator to adequately support gas exchange, allowing successful performance of total liquid ventilation....
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PMID: 15483421
PDF is available here.
PDF is available here.
Abstract
Abstract
An ultra-short acting glycoprotein IIb/IIIa antagonist, FK633, is effective in preventing both platelet aggregation and thrombocytopenia during CPB, and may be effective for minimizing postoperative bleeding....
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PMID: 15296885
PDF is available here.
PDF is available here.