Abstract
We investigate preventive and therapeutic effects of placental extract in contact hypersensitivity (CHS), a mouse model of allergic contact dermatitis. Administration of placental extract prior to the sensitization of allergic antigen (Ag) significantly inhibited the severity of CHS induced by Ag ch...
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PMID: 20619383
PDF is available here.
Abstract
We analyzed autogenous marrow aspirates obtained from three different graft sites for the mRNA levels of BMPs and their receptors.
Using real-time polymerase chain reaction, we analyzed the mRNA levels of BMPs and their receptors in autogenous bone marrow aspirates obtained from three different bone...
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PMID: 20736795
PDF is available here.
Abstract
Osteogenesis is a complex process that involves the synergistic contribution of multiple cell types and numerous growth factors (GFs). To develop effective bone tissue engineering strategies employing GFs, it is essential to delineate the complex and interconnected role of GFs in ost...
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PMID: 20184436
PDF is available here.
Abstract
I collagen. The experimental results showed that when compared with the normal flow, the swirling flow generated in the test tube significantly reduced the platelet adhesion to the surface of the test tube. Different from normal flow condition under which platelet adhesion increased simply with decr...
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PMID: 19304314
PDF is available here.
Abstract
Open thoraco-abdominal aortic aneurysm repair is a demanding procedure with high impact on the patient and the operating team. Results from expert centres show mortality rates between 3-21%, with extensive morbidity including renal failure and paraplegia. Endovascular repair of abdominal aortic aneu...
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PMID: 20354484
PDF is available here.
Abstract
These results suggest that human neural stem cell transplants enhance endogenous brain repair through multiple modalities in response to HI....
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PMID: 20075340
PDF is available here.
Jie J Shen,
Xiaoling X Fu,
Lailiang L Ou,
Min M Zhang,
Yong Y Guan,
Kai K Wang,
Yongzhe Y Che,
Deling D Kong,
Gustav G Steinhof,
Wenzhong W Li,
Yaoting Y Yu and
Nan N Ma
Abstract
Our results demonstrated that the PCL-L electrospun fibrous scaffold has a high potential for a tissue-engineered ureter especially when seeded with BM-MSCs, which enhanced angiogenesis....
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PMID: 20383857
PDF is available here.
Abstract
Mycophenolic acid (MPA) is a cornerstone immunosuppressant therapy in solid organ transplantation. MPA is metabolized by uridine diphosphate glucuronosyltransferase to inactive 7-O-MPA-glucuronide (MPAG). At least three minor metabolites are also formed, including a pharmacologically active acyl-glu...
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PMID: 20235793
PDF is available here.
Abstract
We were unable to prefabricate a functional vascularized nerve graft by this method....
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PMID: 20179484
PDF is available here.
Abstract
Based on the analysis of the 52 patient cases submitted for the Antibody Treatment Report of Clinical Transplants 2010, there is growing evidence that bortezomib is a viable option for antibody mediated rejection (AMR). Today, some centers have even chosen to use bortezomib as a firs...
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PMID: 21696053
PDF is available here.
Abstract
We analyzed 14 cord blood samples by flow-FISH, ELISA and gematologycal analisator, and also the number of CD34 + CD45dim cells. Average telomere length of leukocytes fraction CB cells was 20.4-4.9 % respectively the control cells 1301 (T-cell lymphoblastic leukemia)....
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PMID: 21427985
PDF is available here.
Abstract
We have reviewed relevant literature on transplantation and clinical mycology of the last 20 years and selected articles relevant for today's treatment decisions. This article reports on the epidemiology of IFD in transplant recipients and current antifungal drugs in the context of tansplantation me...
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PMID: 20001432
PDF is available here.
Abstract
Peyronie's disease (PD), a localized fibrosis of the tunica albuginea surrounding the penile corpora, results in penile curvature and sexual dysfunction. Men with significant penile curvature and satisfactory erectile function are often treated with plaque incision or excision and gr...
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PMID: 19863858
PDF is available here.
Abstract
Peyronie's disease (PD), a localized fibrosis of the tunica albuginea surrounding the penile corpora, results in penile curvature and sexual dysfunction. Men with significant penile curvature and satisfactory erectile function are often treated with plaque incision or excision and gr...
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PMID: 19863858
PDF is available here.
D V Subbotin,
P M Larionov,
D S Sergeevichev,
O A Subbotina,
G S Zaitsev,
R B Novruzov,
A M Orishich,
A N Malov,
N A Maslov,
I A Rozhin,
E L Lushnikova and
L M Nepomnyashih
Abstract
We performed a fluorescent microscopic examination of human and animal aortic grafts at different stages of decellularization. Treatment of aortic grafts with trypsin/EDTA solution for 48 h leads to their complete decellularization and preserved the connective tissue fiber backbone, which gains a ne...
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PMID: 20396770
PDF is available here.
M Ok,
J P Latge,
C Baeuerlein,
F Ebel,
M Mezger,
M Topp,
O Kurzai,
D Killian,
M Kapp,
G-U Grigoleit,
H Sennefelder,
J Arroyo,
H Einsele and
J Loeffler
Abstract
We analyzed the immune response of iDCs to different recombinant A. fumigatus antigens (Aspf1 and Crf1). One of these antigens, the 18-kDa RNase Aspf1, triggered the increased level of expression of genes encoding proinflammatory cytokines and chemokines, and augmented the activation of NFkappaB and...
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PMID: 19675222
PDF is available here.
Abstract
Collectively, the data presented here suggest that the use of human amnion as a source of amniotic stem cells provides a very promising tool for tissue reconstruction....
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PMID: 19721391
PDF is available here.
Ron Shapiro,
Amit Basu,
Henkie P Tan,
Claire Morgan,
Vivek Sharma,
Deanna Blisard,
Parmjeet S Randhawa,
Igor Dvorchik,
Jerry McCauley,
Demetrius Ellis,
J Wallis Marsh,
Steven Webber,
Geoffrey Kurland,
Kenneth R McCurry,
Kareem Abu-Elmagd,
George Mazariegos and
Thomas E Starzl
Abstract
We sought to evaluate the role of alemtuzumab induction in this population.
We evaluated 144 patients undergoing kidney transplantation after nonrenal transplantation between May 18, 1998, and October 8, 2007. Seventy-two patients transplanted between January 15, 2003, and October 8, 2007, received...
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PMID: 19920779
PDF is available here.
Abstract
Mixed chimerism established by nonmyeloablative conditioning induces long-term acceptance of CTA, which is associated with persistent chimerism preferentially in the transplanted donor bone....
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PMID: 19920776
PDF is available here.
Abstract
We discuss the interactions between regenerative biology and engineering, in the context of (i) creation of functional tissue grafts for regenerative medicine (where biological input is critical), and (ii) studies of stem cells, development and disease (where engineered tissues can serve as advanced...
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PMID: 19146967
PDF is available here.
Abstract
We used microarrays to examine whole genome expression profiles using tissue from 53 human renal allograft protocol biopsies obtained both at implantation and after transplantation. The gene expression profiles of living-donor kidneys and pristine deceased-donor kidneys (normal histology, young age)...
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PMID: 19443638
PDF is available here.
Abstract
We study the impact of graft- versus host-derived serotonin innervation. All experiments were performed in l-DOPA treated rats with unilateral 6-hydroxydopamine lesions. As expected, following intrastriatal transplantation of embryonic ventral mesencephalon all the transplanted rats exhibited pronou...
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PMID: 19361557
PDF is available here.
Abstract
Animal survivals were as follows: Group A, 5/5, Group B, 5/5 and Group C, 1/5. PVP rose immediately after reperfusion. PVP in Group C peaked to 28.6 +/- 2.07 mm Hg. Portal blood flow (PBF) measured by CDFI showed that the index of PBF per gram liver tissue reached 3.56 +/- 0.11 ml x min(-1) x g(-1)...
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PMID: 19953877
PDF is available here.
Abstract
The saddle nose deformity results from a disruption in the nose's integral support mechanisms. Reconstructive surgeons must not only reestablish facial aesthetic contours but also rebuild the nose's structural framework while preserving or restoring nasal function. The causes and the classification...
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PMID: 19486741
PDF is available here.
Abstract
We explore the progress we have made in treating the nasal valves, and the deficiencies we still face....
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PMID: 19486744
PDF is available here.
Abstract
The nasal septum is a structure poorly understood and appreciated by the lay public and the nonotolaryngologist--head and neck surgeon alike. Deviation of the caudal portion of the nasal septum may result in nasal obstruction, a crooked nose, and columellar irregularities. The correction of a severe...
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PMID: 19486740
PDF is available here.
Abstract
We present three patients who underwent a deceased donor renal transplant and developed posttransplant diabetes mellitus. In all three patients despite excellent glycemic control (HbA1c....
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PMID: 19473643
PDF is available here.
Abstract
The anterior cruciate ligament (ACL) is one of the most frequently torn ligaments of the knee. With more than 100,000 ACL reconstructions performed yearly in the United States, evaluation of ACL grafts with magnetic resonance imaging is a common occurrence in daily clinical practice. Anterior crucia...
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PMID: 20410802
PDF is available here.
Abstract
To prepare the tissue-engineering ossicle prosthesis which contained controlled release BMP-2 and implant into the acoustic bulla of guinea-pig, and observed the osteogenesis of the prosthesis in the bulla and the effect of the prosthesis on the cochlea.
The acellular...
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PMID: 19954021
PDF is available here.
Abstract
Treatment of patients with chronic hepatitis B virus (HBV) infection who have advanced disease or comorbidities can be challenging, and recommendations may differ from standard guidelines. Among the special populations that merit specific consideration are patients with compensated or decompensated...
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PMID: 19399810
PDF is available here.
Abstract
Reactivation of hepatitis B refers to the abrupt increase in hepatitis B virus (HBV) replication in a patient with inactive or resolved hepatitis B. Reactivation can occur spontaneously, but more typically is triggered by immunosuppressive therapy of cancer, autoimmune disease, or organ transplantat...
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PMID: 19399803
PDF is available here.
Abstract
We concluded that patients undergoing ACL reconstruction with BPTB non-irradiated allograft or autograft had similar clinical outcomes. Non-irradiated BPTB allograft is a reasonable alternative to autograft for ACL reconstruction. While the short term clinical outcomes of the ACL reconstruction with...
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PMID: 19139845
PDF is available here.
Abstract
Tissue engineering is an emerging multidisciplinary field of investigation focused on the regeneration of diseased or injured tissues through the delivery of appropriate molecular and mechanical signals. Therefore, bone tissue engineering covers all the attempts to reestablish a normal physiology or...
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PMID: 18729202
PDF is available here.
Abstract
In the past 50 years, organ transplantation has developed from an improbable laboratory exercise to a major therapeutic success. The surgical problems of organ grafting have, for the most part, been solved. Rejection of grafts is now partially understood and usually controllable by powerful immunosu...
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PMID: 19434339
PDF is available here.
Abstract
All the posterior-pedicle labium minus flaps survived, except for 3 cases in which the epidermis 1 cm around the distal end of posterior-pedicle labium minus flap was exfoliated and recovered 2 weeks after hip bath with potassium permanganate solution (1:5000). All the anterior-pedicle labium minus...
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PMID: 19431985
PDF is available here.
Abstract
Microarrays have been useful in identifying potential biomarkers for chronic rejection in peripheral blood mononuclear cells, novel pathways for induction of tolerance, and genes involved in protecting the graft from the host immune system. Microarray analysis of peripheral blood mononuclear cells f...
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PMID: 19337144
PDF is available here.
Abstract
All the incisions were healed by first intention. Trailing status and toe's dysfunction in extension happened to the right hindlimb of rats in two groups and were improved 6 weeks after operation. General observation showed that the grafts of two groups connected well to the nerves, with appearances...
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PMID: 19275112
PDF is available here.
Abstract
Although it is well accepted that T cells are the major effector cells in acute rejection, there is an increasing recognition that cells of the innate immune system, and in particular NK cells, also play a major role in allograft rejection. SUMMARY: Both NK cells and cytotoxic T cells contribute to...
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PMID: 19337143
PDF is available here.
Abstract
Recent findings have included identification of the signals that drive naive T lymphocytes to express Foxp3 in the thymus and the signals peripherally that induce non-Foxp3 expressing T cells to express FOXP3. Further, the identification of the downstream targets of Foxp3 both by analysis of Foxp3 e...
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PMID: 19337145
PDF is available here.
Abstract
The mastoid bone graft provides adequate autologous bone in most cases of primary or revision rhinoplasty. The donor site carries low morbidity and a well camouflaged scar. It is easily accessible especially for the otolaryngologist who is accustomed to operating on the mastoid bone....
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PMID: 19788797
PDF is available here.
Abstract
Use of synthetic osteoplastic materials not always leads to formation of the necessary bone tissue volume. The alternative high technological implantation material can become tissue engineering constructions containing osteogenic precursor cells. Clinical observation of sinus lifting with the use of...
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PMID: 20081777
PDF is available here.
Abstract
Vascular catheter use in children on HD therapy is high. This is partially explained by expeditious transplantation and technical barriers to AVF/AVG placement in small children; however, only one-third of patients with a vascular catheter underwent transplantation within 1 year. Interventions to de...
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PMID: 18950912
PDF is available here.
Abstract
ISSUE: On August 1, 2007, the Law on the Quality and Safety of Human Tissues and Cells came into force. IMPLICATIONS: As a consequence of the new legislation on human tissue, legislative changes were effected upon the Law Regulating Transplantations, Medicine Law and Transfusion Law and the regulati...
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PMID: 19494644
PDF is available here.
Abstract
When all parameters were considered it was found out that the tunnel localizations in the sagittal tibial plane solely and independently had a significant effect on knee functions. CONCLUSION: It was concluded that especially the tibial tunnel located sagittally in the anterior second half of the pl...
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PMID: 19522688
PDF is available here.
Abstract
We describe the eFOSTr PROJECT, which has involved the design, implementation and testing of a unique Internet-based Personal Health Record (PHR) to support the families of transplant children and their healthcare providers. There are many gaps in the way that information is stored for children unde...
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PMID: 19380961
PDF is available here.
Abstract
Nearly 40 years have passed since the publication of the first report showing higher cancer risks in recipients of organ transplants. Thereafter, studies carried out in immunosuppressed persons have greatly expanded our knowledge on the spectrum of cancers associated with infections. Clinical invest...
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PMID: 19109791
PDF is available here.