Abstract
This review presents the rationale and supporting data for a recent paradigm shift in our understanding of meibomian gland dysfunction (MGD). The historical understanding of MGD has been that of an infectious hypersecretory disorder with obvious signs of inflammation, hypersecretion, and purulent ex...
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PMID: 20847669
PDF is available here.
Abstract
Obstructive sleep apnea is a diagnosis that ophthalmologists can screen for when a patient presents with certain risk factors. Recent literature provides strong data for associations between sleep apnea and ocular disorders.
A potentially serious disorder, sleep apnea can lead to many systemic and o...
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PMID: 20811281
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Abstract
Both horses had a unilateral, fluctuant mass involving the lower eyelid. For horse 1, the mass had been present since birth and had slowly increased in size over time. The mass also changed in size in response to various environmental stimuli, alterations in the position of the horse's head, and dig...
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PMID: 20946082
PDF is available here.
Abstract
We detected a subtle lagophthalmos, which was complicated by upper eyelid retraction in the right eye. A bilateral upper blepharotomy improved the keratopathy.
Patients with AIDS with severe weight loss can present with lagophthalmos because of adipose and muscular atrophy in the so-called wasting s...
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PMID: 20628297
PDF is available here.
Abstract
To perform a retrospective evaluation of a new treatment for obstructive meibomian gland dysfunction (O-MGD) using invasive orifice penetration and intraductal probing.
Office-based ophthalmology private practice.
Medical charts of 25 consecutive patients with O-MGD (based on presence of lid margin...
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PMID: 20622668
PDF is available here.
Abstract
On the basis of these findings, we recommend that physicians use ocular symptom score and lid margin abnormality score in the diagnosis of seborrheic MGD. Seborrheic MGD should be considered very likely when both of the 2 scores are abnormal....
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PMID: 20628302
PDF is available here.
Abstract
We collected clinical information from all 45 living members of a complete family of 48 members and performed molecular analysis of the FOXC2 gene in 30 individuals. We obtained spinal magnetic resonance imaging from all family members with a FOXC2 gene mutation.
Twelve family members carried a muta...
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PMID: 20535019
PDF is available here.
Abstract
I and II bands. A training set of spectra was used to discriminate between Mn and Md with an accuracy of 93%. This shows that certain spectral regions (eigenvectors) contain compositional and structural information about the changes that occur with the principal component (variable), meibomian gland...
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PMID: 20546726
PDF is available here.
Abstract
Improvement in phase transition temperature of the meibomian gland lipid with the determined percent trans rotomer composition of the lipid strongly suggests that the ordering of the lipid molecules is altered in the disease state (MGD) and that azithromycin can improve that abnormal condition towar...
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PMID: 20489573
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Abstract
PURPOSE. To study screening methods and associated factors of Meibomian gland disease and dry eye subtypes in a specialized eye clinic in Singapore. METHODS. This cross-sectional study involved 200 patients in a dry eye clinic. The outcome measures evaluated were dysfunctional tear syndrome (DTS) le...
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PMID: 20181848
PDF is available here.
Abstract
To describe an acquired, smooth white lesion of the caruncle and to underscore the role of subsurface keratinizing squamous epithelium in its formation.
Clinical photographic documentation, histopathologic evaluation, and immunohistochemical staining of an excised specimen from a 25-year-old woman....
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PMID: 20164755
PDF is available here.
Abstract
Azithromycin 1.5% for 3 days (six drops) was as effective as tobramycin for 7 days (36 drops). Furthermore, patients on azithromycin presented earlier clinical cure on Day 3 than patients on tobramycin. Azyter, with its convenient dosing (bid for 3 days), is a step forward in the management of purul...
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PMID: 20223555
PDF is available here.
Abstract
The case of a 57-year-old man with a radix relicta in the maxillary sinus causing a chronic maxillary sinusitis with secondary alteration of orbit and maxillary sinus, compatible with the silent sinus syndrome, is presented. The patient was treated with intranasal antrostomy in which the underlying...
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PMID: 20489466
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Abstract
We present a unique case of a patient with severe unilateral facial lymphedema, which manifested many years after extirpation of a floor-of-the-mouth squamous cell carcinoma, bilateral supraomohyoid neck dissections, and radiation therapy. The massive cheek and eyelid lymphedema, which extended from...
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PMID: 20489462
PDF is available here.
Abstract
Despite early satisfactory results with good closure, six out of 12 implants were extruded within the first year. Two more implants had to be removed due to chronic inflammatory reaction. CONCLUSION: Long term result of gold weight implants in leprosy patient is unsatisfactory and needs further eval...
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PMID: 20496572
PDF is available here.
Abstract
In cases with both lower eyelid retraction and epiblepharon, the retraction should be repaired first, and then the epiblepharon can be corrected selectively according to the severity of the case....
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PMID: 20157407
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Abstract
We report nine cases of lid leishmaniasis with satisfactory responses to intralesional meglumine antimoniate....
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PMID: 20157413
PDF is available here.
Abstract
We have treated many older patients with upper blepharochalasis but no obvious aponeurotic ptosis by infraeyebrow excision of skin and orbicular muscle with tucking of the orbital septum. Thirty-five patients (70 lids) were studied, age range 61-80 years (mean 68). There were 6 men and 29 women, who...
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PMID: 20136468
PDF is available here.
Abstract
Tear EGF concentration was increased in eyes with MGD, corneal subepithelial fibrosis, and MG orifice metaplasia. Elevated tear EGF may promote development of corneal subepithelial fibrosis and lid margin changes....
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PMID: 19815739
PDF is available here.
Abstract
The authors present a female case diagnosed with Gorlin syndrome before admission to the Ophthalmology clinic. There are presented types of diagnosis, evolution and treatment in this case.
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PMID: 21516867
PDF is available here.
Abstract
We report a case of multiple periocular xanthogranulomas arising in a 43 year old man with chronic lymphocytic leukaemia. This case supports the emerging hypothesis that both juvenile and adult xanthogranulomas may share an association with an underlying haematological malignancy. Also highlighted i...
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PMID: 19919911
PDF is available here.
Abstract
In this sample of moderate evaporative-type DED patients, five inflammatory molecules were elevated. Fracktalkine was demonstrated to be present and elevated in tears in human DED. IL-1Ra, IL-6, IL-8/CXCL8, and EGF levels correlated with pain and with clinical parameters measuring tear stability, te...
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PMID: 20508732
PDF is available here.
Abstract
Treating eyelid divided defects with adjacent or distant island skin flap is a suitable method with satisfactory result and less morbidity in donor sites....
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PMID: 20432918
PDF is available here.
Katharina E Schmid-Kubista,
Lukas Kellner,
Harald Maier,
Stefan Felke,
Alexandra Wanka,
Adel El Modeir,
Jolanta B Schmidt,
Alexander Cabaj,
Alois Schmalwieser,
Herbert Rohn,
Heinrich Stadelmann,
Johannes Spiess,
Wolfgang Fischer,
Herbert Hönigsmann and
Susanne Binder
Abstract
Three hundred and ninety-two subjects underwent ophthalmic examinations of whom 297 were farmers and 95 were controls. Due to the survey, 89.7% of the farmers claimed to protect themselves from the sun during work. From these subjects, 83.7% wear a head protection, 71.0% wear sunglasses, and 54.4% u...
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PMID: 20068373
PDF is available here.
Abstract
Reconstruction of the upper eyelid is one of the greatest challenges facing the orbitofacial surgeon. This comprehensive review outlines the principles of reconstruction and the range of techniques available. Methods of assessing upper eyelid defects are discussed, and an algorithm for reconstructio...
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PMID: 20083289
PDF is available here.
Abstract
We report a rare instance of favorable outcome in orbital apex syndrome secondary to herpes zoster ophthalmicus (HZO) in a human immunodeficiency virus (HIV)-positive patient. The patient complained of pain and decrease in vision in one eye (20/640) for 2 weeks accompanied with swelling, inability t...
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PMID: 20952840
PDF is available here.
Abstract
The outcomes of keratitis in lagophthalmos occurring due to various causes despite therapeutic measures are generally poor. The influence of factors, such as drying of the cornea, impairment of its trophism, and infection, leads to the development of rough leukomas, and occasionally to eye death due...
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PMID: 21105377
PDF is available here.
Abstract
The authors report the results of the first experience in using the stabilized hyaluronic acid preparation in patients with lagopthalmos in the presence of facial nerve palsy and thyroid eye disease and resultant keratopathy of varying degrees. The study included 21 patients, including 15 patients w...
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PMID: 20645575
PDF is available here.
Abstract
Diminished levator excursion is associated with increasing levels of eyelid lag and lagophthalmos. Levator excursion is an important clinical measurement in thyroid eye disease patients and may replace eyelid lag grading and lagophthalmos as a more accurate indicator of eyelid retraction in thyroid...
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PMID: 20090475
PDF is available here.
Abstract
A 40-year-old male presented with swelling and erythema in his right upper eyelid that began 4 months prior. Clinical evaluation, rheumatologic serology, sedimentation rate of erythrocyte, and C-reactive protein results were all normal. The patient also did not respond to local and systemic antibiot...
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PMID: 20090498
PDF is available here.
Abstract
A rare case of right eye lime burns resulting in total conjunctival defect, enucleation, and fused eyelids is reported. This article describes total conjunctival sac reconstruction using a split-thickness skin graft combined with a spherical orbital implant, which may be a good choice for treating s...
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PMID: 20090486
PDF is available here.
Abstract
Our 2 patients presented with the typical clinical findings of small papular lesions in which histopathologic examinations disclosed granulomatous inflammation with necrosis associated with inflamed hair follicles. Except for its description as acne agminata by Duke-Elder in 1974, to the authors' kn...
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PMID: 20090495
PDF is available here.
Abstract
Rhodococcus species are rare human pathogens. Most cases of human infection have involved Rhodococcus equi, a natural zoonotic pathogen causing pneumonia in young foals. The human population at risk mainly includes immunocompromised patients. Infection of immunocompetent hosts has been rare, with le...
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PMID: 20305518
PDF is available here.
Abstract
We discuss these associations along with the possible pathophysiological mechanisms and clinical management. It is needed that the ophthalmologist, the primary care physician and the sleep physician are aware of this association so that both sleep disorders and the related ophthalmologic disorders c...
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PMID: 19473675
PDF is available here.
Abstract
A 31 year old black Haitian male presents with severe nodular induration and erythema of both eyelids with hemorrhagic infiltration of the bulbar and palpebral conjunctivae, advanced on the right. Clinical, histological, and immunohistochemical examination yielded the diagnosis of Kaposi's sarcoma....
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PMID: 19654515
PDF is available here.
Abstract
Although S. aureus on the lid margin plays an important role in the onset of catarrhal ulcers, its presence is one among several risk factors....
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PMID: 19574908
PDF is available here.
Abstract
AMCase activity was significantly increased in patients affected by MGD dry eye (18.54 +/- 1.5 nmol/ml/h) and SS dry eye (8.94 +/- 1.0 nmol/ml/h) respectively, compared to healthy controls (1.6 +/- 0.2 nmol/ml/h). AMCase activity was higher in the tears of subjects with MGD dry eye (P < 0.001). AMCa...
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PMID: 19512904
PDF is available here.
Abstract
The choice of surgical procedure considering the age of the patient, the genesis and the exact localisation of the pathology is of utmost importance in order to achieve ideal post-operative results.
Georg Thieme Verlag KG Stuttgart, New York...
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PMID: 19644799
PDF is available here.
Abstract
We are presenting this rare complication with the hope of elucidating further on clinical course of illness and literature review on the possible pathophysiological mechanism....
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PMID: 19225782
PDF is available here.
Abstract
The article presents abnormalities of the eyelids, the orbita and the periorbital areas. One part of these conditions disrupts vision, the main function of the eye. The other reasons why they require correction are the aesthetic value of this distinctly visible area of the body and the necessity of...
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PMID: 19362915
PDF is available here.
Abstract
The eyelids, essential to protecting and cleansing the eye, are a common site for a range of disorders affecting older adults. Some of these are benign and some serious, with the most clinically important being suspicious lid lesions that may harbor malignancy and neurologic disorders, as well as st...
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PMID: 19400595
PDF is available here.
Abstract
We report the case of a three years oÃd child with bilateral NF of the eyelids and toxic shock syndrome secondary to Streptococcus pyogenes infection occurring after a minor skin trauma. Early recognition leading to intensive care treatment and prompt surgical debridement were critical in the fav...
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PMID: 19621147
PDF is available here.
Abstract
We describe our experience with 16 cases of intralymphatic histiocytosis. Clinically, the lesions were located predominantly on the upper and lower limbs, and they consisted of asymptomatic and poorly demarcated erythematous plaques and livedo reticularis-like lesions. They were characterized histop...
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PMID: 19318799
PDF is available here.
Abstract
A 74-year-old man from the rural area of Caicedonia, Valle del Cauca Province, was diagnosed with uncontrolled hypertension, stage IV chronic renal failure and severe anemia. Fifteen years earlier, while living in Guaviare Province, he was diagnosed with leishmaniasis-with lesions located on the rig...
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PMID: 19753833
PDF is available here.
Abstract
We report the case of a 58-year-old female with history of rosacea who developed bilateral periorbital swelling with associated erythema of the conjunctiva (ocular rosacea) over a 4 month period that only responded to oral corticosteroids. Biopsy revealed changes of lymphedematous rosacea....
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PMID: 19266745
PDF is available here.
Abstract
Microbial keratitis in Down syndrome is associated with eyelid problems and ocular atopy, and due to failure of medical therapy alone, surgical intervention is required in majority of cases....
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PMID: 19158558
PDF is available here.
Abstract
Xanthelasma is a common disfiguring condition, which can be difficult to treat. Various treatments have been reported previously with varying degree of success. We report a simple yet effective technique of excision of the lesions with excellent cosmetic outcome.
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PMID: 19200199
PDF is available here.