Abstract
A 62-year-old man presented with diplopia, ocular ductional deficits, and sluggish pupils. Pupillometry demonstrated large hyporeactive pupils with no evidence of damage to the sympathetic or parasympathetic innervation, indicating a myopathy of the iris musculature. A single large deletion in mitoc...
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PMID: 20414131
PDF is available here.
Abstract
Results obtained in the study are discussed and compared with the related current literature. The overall mortality in 113 patients was 56.6%. CONCLUSION: According to the results, the most important determinants of the prognosis are GCS score of the patient on admission, abnormality in pupil reacti...
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PMID: 20517749
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Abstract
AL of myopic eyes was significantly longer. In general, hyperopia was positively correlated with BW, whereas correlation between myopia and BW or GA was not found....
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PMID: 20121489
PDF is available here.
Abstract
Vision was NLP in all eyes at the time of surgery, which was performed 3 days to 14 days after the initial trauma. During a mean follow-up period of 20.5 +/- 5.2 months (range, 11-36 months), except for 1 case of phthisis, other eyes achieved acceptable anatomical and functional outcomes. Postoperat...
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PMID: 19952999
PDF is available here.
Abstract
We report two Creutzfeldt-Jakob disease (CJD) patients with rhythmic pupillary and palpebral oscillation who had a mutation of prion protein codon 200 that resulted in the substitution of lysine for glutamate (Glu/Lys). Alternating dilation and constriction of the pupils combined with elevation and...
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PMID: 20077484
PDF is available here.
Abstract
We identified complex interactions and mutual information in many of the parameters. Variables predicting death differ from those predicting unfavorable versus favorable outcomes (Glasgow Outcome Scale scores of 1-3 versus 4-5 [GOS]). The most important parameter for prediction of unfavorable outcom...
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PMID: 19698072
PDF is available here.
Abstract
We describe the case of a 78-year-old highly myopic woman who had bilateral phacoemulsification with posterior chamber intraocular lens implantation. During surgery, the anterior chamber was extremely deep and the pupil was excessively dilated, consistent with lens-iris diaphragm retropulsion syndro...
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PMID: 20117722
PDF is available here.
Abstract
We report a penetrating orbital injury caused by a bread knife that extended from the orbit to the tegmental dura mater of the temporal bone. The knife's main trajectory coursed through the temporal lobe. Adjacent cerebral structures were explored before removal of the knife....
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PMID: 19830370
PDF is available here.
Abstract
The median age at diagnosis was 1.6 years (range, 0-5.9) with a median follow-up of 1.8 years (range, 0.1 to 11.6). The median time from presenting signs to the time of diagnosis was 5.2 months (range, 0-25.2). Common presenting signs of retinoblastoma were identified; the most common of which were...
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PMID: 19736573
PDF is available here.
Abstract
A secondary angle closure associated with DSEK is reported with air migrating behind the iris, resulting in extensive iridocorneal adhesions. An acute increase in IOP after DSEK can also be induced by air anterior to the iris causing pupillary block. IOP spikes are much more common in the first few...
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PMID: 19512906
PDF is available here.
Abstract
This binocular pupillometer identified all of our patients with > 0.5 log unit rAPDs. Using NDFs, all of our abnormal patients were accurately identified and their rAPDs quantified. Variability in some normals makes them indistinguishable from patients with subtle rAPDs....
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PMID: 19899974
PDF is available here.
Abstract
Iris atrophy and pupillary dilation in a patient with unexplained anterior uveitis suggests the diagnosis of HSV keratouveitis....
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PMID: 19491988
PDF is available here.
Abstract
We describe a patient with PTC and CNV whose CNV regressed and vision normalized after a single intravitreal injection of bevacizumab (Avastin; Genentech, San Francisco, CA)....
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PMID: 18196206
PDF is available here.
Abstract
Ninety-two (7.8%) of 1172 patients had a GCS of 3 and BFDP; eight had 'good', 84 had 'poor' recovery. We found no significant differences in sex (79% male), age (median 32 years), and trauma mechanisms. Trauma was significantly less severe, probability of survival significantly higher (0.48 vs. 0.23...
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PMID: 19282759
PDF is available here.
Abstract
Pupil tests provide a convenient and simple method for evaluation of autonomic function. Most patients with autonomic disorders show evidence of sympathetic or parasympathetic deficits in the pupil, and these can be detected using a combination of clinical signs, pupillometric tests (measuring the r...
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PMID: 19190959
PDF is available here.
Abstract
Traumatic optic neuropathy is a severe complication of a head or face trauma. Diagnosis is established by analyzing pupillary responses to light. Fundus examination and orbital CT scan help to localize the site of the lesion and may show a fracture involving the optic canal. Surgical decompression o...
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PMID: 19247896
PDF is available here.
Abstract
: The technique of FALT is simple and efficient for treating cosmetically blind eyes with leukocoria and may overcome the limitations of previously reported techniques. The long-term safety of the commercially available corneal tattoo dyes should be studied further....
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PMID: 19158567
PDF is available here.
Abstract
Ninety-three patients fulfilled the criteria for inclusion into the study. There were 6 survivors who were all less than 28 years of age, had at least one GCS score above 3 in the pre-hospital phase and were more likely to have had an evacuable mass lesion on CT brain scan and undergo craniotomy. Of...
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PMID: 19070839
PDF is available here.
Abstract
A new PASCAL laser photocoagulator (OptiMedica, USA) was clinically tested. A total of 38 laser interventions were performed in 38 eyes with diabetic retinopathy (n = 25), peripheral retinal dystrophy (n = 2), retinal ruptures (n = 2), hemophthalmos (n = 3), primary open-angle glaucoma (n = 5), and...
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PMID: 19824447
PDF is available here.
Abstract
The presence of neovascular AMD significantly affects the pupil's response to light stimulus when compared to normal subjects....
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PMID: 19253243
PDF is available here.
Abstract
We will review the anatomic predisposing factors, their physiology, signs and symptoms, and therapeutic approach. We will consider two studies and discuss the visual results and risk factors associated with these pathologic conditions....
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PMID: 19696897
PDF is available here.
Abstract
A 25-year-old woman was diagnosed to have tubercular meningitis (TBM) with a right parietal infarct. She responded well to four-drug anti-tubercular treatment (ATT), systemic steroids and pyridoxine. Steroids were tapered off in one and a half months; she was put on two-drug ATT after two months. Si...
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PMID: 19237788
PDF is available here.
Abstract
OTS calculated at initial examination may provide prognostic information in children with open-globe injuries....
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PMID: 19077614
PDF is available here.
Abstract
We identified 5 clinical patterns of peripheral neuropathy: (1) generalized autonomic failure and polyneuropathy with pain (40 patients [62%]), (2) generalized autonomic failure and polyneuropathy without pain (11 [17%]), (3) isolated generalized autonomic failure (7 [11%]), (4) polyneuropathy witho...
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PMID: 18990321
PDF is available here.
Abstract
We present a case of a patient who had pupilloplasty for an atonic pupil following phacoemulsification cataract surgery. Postoperatively, the patient experienced glare that was not relieved by a neodymium:YAG laser capsulotomy. A cosmetic contact lens helped to resolve the symptoms. In cases of glar...
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PMID: 19006752
PDF is available here.
Cecilie Bredrup,
Verena Matejas,
Margaret Barrow,
Kvĕta Bláhová,
Detlef Bockenhauer,
Darren J Fowler,
Richard M Gregson,
Iwona Maruniak-Chudek,
Ana Medeira,
Erica Laima Mendonça,
Mikhail Kagan,
Jens Koenig,
Hermann Krastel,
Hester Y Kroes,
Anand Saggar,
Taylor Sawyer,
Michael Schittkowski,
Janusz Swietliński,
Dorothy Thompson,
Rene G VanDeVoorde,
Dienke Wittebol-Post,
Geoffrey Woodruff,
Aleksandra Zurowska,
Raoul C Hennekam,
Martin Zenker and
Isabelle Russell-Eggitt
Abstract
Loss-of-function mutations in laminin beta2 (LAMB2) cause a broad range of ocular pathology, emphasizing the importance of laminin beta2 in eye development. Patients with Pierson syndrome can initially present with ocular signs alone. In newborns with marked bilateral microcoria, Pierson syndrome sh...
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PMID: 18672223
PDF is available here.
Abstract
Immediate treatment was required when zone I ROP was diagnosed behind persistent hazy media....
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PMID: 18602081
PDF is available here.
Abstract
The frequent coexistence of harlequin and Horner syndromes without other neurologic deficits suggests pathologic changes affecting the superior cervical ganglion. Because either syndrome may occur alone, damage is apparently selective. Among the patients with harlequin syndrome who also have tonic p...
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PMID: 18769278
PDF is available here.
Abstract
Our patient serves as a reminder that isolated internal ophthalmoplegia with cholinergic supersensitivity is compatible with a preganglionic compressive third nerve lesion, particularly in a young child....
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PMID: 18769282
PDF is available here.
Abstract
We report a 40-year-old woman who developed Ross syndrome (impairment of sweating and thermoregulation, tonic pupils, and hyporeflexia) associated with cytomegalovirus (CMV) infection. Her serum CMV IgM and IgG antibody titer levels were elevated. Along with clinical improvement, a gradual decrease...
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PMID: 18508347
PDF is available here.
Abstract
There were only 3 dislocations into the anterior chamber in this series of 200 consecutive eyes (1.5% dislocation rate) and all were successfully reattached with a second air bubble. There were no dislocations in the last 115 consecutive cases. There were two cases of donors that were attached but d...
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PMID: 18061268
PDF is available here.
Abstract
Cataract remains the most important cause of preventable blindness in this poor region of China, and affordable provision of surgery would help to address this problem. Some cases of cataract blindness may not be preventable owing to preexisting comorbidity, as detected by the presence of a pupillar...
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PMID: 17953988
PDF is available here.
Abstract
Our results suggest that both parasympathetic and sympathetic pupillary functions are disturbed already early in the course of MS. However, the disturbance is not severe at this stage of the disease. The dysfunction is age-dependent and thus possibly related to the dimished remyelination capacity of...
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PMID: 18461280
PDF is available here.
Abstract
Pupillary evaluation of retinal asymmetry provides a rapid method for detecting and classifying visual field defects. In this patient population, classification agreed with perimetry in 70% of eyes....
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PMID: 18521026
PDF is available here.
Abstract
We hypothesize that 10-degree angulated and broad haptic junctions can lead to zonular damage and IOL subluxation....
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PMID: 18361996
PDF is available here.
Abstract
We present a case of acute angle closure that occurred after insertion of an implantable contact lens (ICL). The apparent papillary-block angle closure did not resolve after 2 patent iridotomies and a surgical iridectomy, but did respond to pupil dilation (not constriction). Ultrasound biomicroscopy...
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PMID: 18361995
PDF is available here.
Abstract
It was demonstrated that the pupillary light reflex (PLR) depends on the input of suprageniculate neurons, thus supporting the involvement of a cortical pathway also. The site of integration of cortical signals in relation to the PLR into the pupillomotor pathway may be located suprageniculately in...
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PMID: 18347318
PDF is available here.
Abstract
We report 3 siblings from a nonconsanguineous white family with bilateral persistent pupillary membranes with dissimilar forms of severity. Two of the patients required no treatment; 1 was treated surgically for occlusion of the pupillary axis and moderate visual acuity decrease. Anterior segment ex...
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PMID: 18299084
PDF is available here.
Abstract
The discovery of photosensitive retinal ganglion cells not serving vision, but serving circadian rhythm and the pupil initiated many studies. There is evidence that pupil reaction to light might be preserved even if all rods and cones are lost. Spontaneous pupillary contractions in darkness occur in...
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PMID: 18180650
PDF is available here.
Abstract
A 39-year-old man with Marfan syndrome underwent scleral fixation using a three-piece foldable intraocular lens and experienced repeated pupillary intraocular lens captures secondary to a pliable iris. As a result, the patient needed an additional pupilloplasty. In the opposite eye,...
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PMID: 18717443
PDF is available here.
Abstract
Hypertension was the most significant risk factor in our patients. Headache was the most common early clinical symptom, while pyramidal signs were the most frequent findings at neurological examination. Patients with hemorrhagic extension to the putamen had the worst prognosis for stroke....
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PMID: 19295005
PDF is available here.
Abstract
Analyses over a long period of time showed progressive ophthalmic findings in a patient with SSPE....
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PMID: 18203105
PDF is available here.
Abstract
In this case luxated lens and pupillary block was caused by constriction of retrolenticular fibrous membrane. Early surgical intervention is necessary to prevent progressive pathologic changes in eyes with this developmental disorder and to obtain the best possible visual results....
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PMID: 19112865
PDF is available here.