Abstract
We show that PS impairs the morphological and functional maturation of hippocampal granule cells in adult offspring via the downregulated expression of mineralocorticoid receptors. PS reduced the dendritic complexity and spine density of neonatal-generated granule cells, which persists into adulthoo...
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PMID: 21832180
PDF is available here.
Abstract
There is growing concern that exposure to air pollutants during pregnancy affects health outcomes in the offspring due to alterations in the development of immune and other homeostatic processes. To assess the risks of maternal inhalation exposure to ozone (O(3)), timed pregnant BALB...
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PMID: 21534884
PDF is available here.
A A Lagares,
P A PA Gómez,
J F JF Alén,
F F Arikan,
R R Sarabia,
A A Horcajadas,
J J Ibañez,
A A Gabarros,
J J Morera,
A A de la Lama,
L L Ley,
J J Gonçalves,
A A Maillo,
J J Domínguez,
J L JL Llacer,
I I Arrese,
D D Santamarta,
P P Delgado,
G G Rodríguez Boto and
J J Vilalta
Abstract
An actualized revision of the most important aspects of aneurismal subarachnoid hemorrhage is presented from the guidelines previously published by the group of study of cerebrovascular pathology of the Spanish Society of Neurosurgery. The proposed recommendations should be considered as a general gu...
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PMID: 21597651
PDF is available here.
Abstract
Our data demonstrate that subclinical endotoxemia is associated with systemic and AT inflammation in obese pregnant women. Recognition of bacterial pathogens may contribute to the combined dysfunction of innate immunity and the metabolic systems in AT....
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PMID: 20930711
PDF is available here.
Abstract
We examined the relationship of maternal insulin resistance (IR), a metabolically important consequence of increased adiposity, to adverse consequences of obesity for fetal development. We used mice heterozygous for a null allele of the insulin receptor (Insr) to study the contributions of maternal...
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PMID: 20948526
PDF is available here.
Abstract
We present a case of a 30-year-old Japanese female with abdominal pain during menstrual periods was suspected of having ovarian cancer due to exaggerated ascites observed at a local clinic. Subsequently, she was transferred to our hospital for further investigations, and was diagnosed with LAM. Thre...
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PMID: 21314806
PDF is available here.
Abstract
The study aimed at identifying the risk factors for neonatal septicaemia in Zaria.
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PMID: 21445109
PDF is available here.
Abstract
We categorized LE into 5 groups. LE caused by virus infection, autoantibody-mediated LE, LE with autoimmune disease, LE associated with drugs and LE during pregnancy. LE having the antibodies against intracellular antigens frequently related to cancer and are resistant to treatment. While, LE with a...
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PMID: 21400836
PDF is available here.
Abstract
Obesity negatively impacts the health of women in many ways. Being overweight or obese increases the relative risk of diabetes and coronary artery disease in women. Women who are obese have a higher risk of low back pain and knee osteoarthritis. Obesity negatively affects both contra...
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PMID: 21209347
PDF is available here.
Ambrogio Orlando,
Alessandro Armuzzi,
Claudio Papi,
Vito Annese,
Sandro Ardizzone,
Livia Biancone,
Aurora Bortoli,
Fabiana Castiglione,
Renata D'Incà,
Paolo Gionchetti,
Anna Kohn,
Gilberto Poggioli,
Fernando Rizzello,
Maurizio Vecchi,
Mario Cottone,
Italian Society of Gastroenterology and
Italian Group for the study of Inflammatory Bowel Disease
Abstract
Biological therapies are an important step in the management of Inflammatory Bowel Diseases. In consideration of high cost and safety issues there is the need to have clear recommendations for their use. Despite the American Gastroenterological Association and the European Crohn's an...
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PMID: 20843756
PDF is available here.
Abstract
We determined the prevalence of first lifetime use of cigarettes during pregnancy or in the early postpartum period (incident smoking) and identified sociodemographic and health-related characteristics of incident smokers.
We used statistics based on data from a longitudinal study of...
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PMID: 21337931
PDF is available here.
Abstract
Anti-TNF-α antibodies are widely used. The indications for their usage are still increasing. With their emerging use, their infectious complications are seen more often. We describe the first case of a pneumonia with Legionella pneumophila in a pregnant women with Crohn's disease, d...
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PMID: 21122583
PDF is available here.
Abstract
We included seven randomised controlled trials in the meta-analysis, all with EPA and/or DHA supplementation. Most studies were judged to be of low-to-moderate quality, mainly due to small sample sizes and failure to adhere to Consolidated Standards of Reporting Trials guidelines. Some studies were...
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PMID: 21078211
PDF is available here.
Abstract
To estimate the risk of women dying from pregnancy complications in the United States and to examine the risk factors for and changes in the medical causes of these deaths.
De-identified copies of death certificates for women who died during or within 1 year of pregnancy and matching birth or fetal...
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PMID: 21099595
PDF is available here.
Abstract
We need to develop an organized, national approach focused on reducing maternal mortality and morbidity. The goal will be to outline a specific plan for clinical, educational, and research initiatives to put the "M" back in maternal-fetal medicine....
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PMID: 21099610
PDF is available here.
Abstract
We describe here the potential of first-trimester markers to screen for Down syndrome as well as other adverse outcomes such as fetal loss, pre-eclampsia, intrauterine growth retardation, and preterm delivery. This early consultation may be the opportunity to help counsel patients and to screen for...
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PMID: 20599860
PDF is available here.
Abstract
Pelvic girdle pain (PGP) usually presents during pregnancy. About 25% of all pregnant women and 5% of all women suffer from postpartum lumbopelvic pain causing them to seek medical help. This article discusses possible causes, diagnostic aspects and treatment of PGP.
The paper is based on literature...
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PMID: 21052118
PDF is available here.
Abstract
We present the case of a 28 year old lady with refractory Crohn's Disease treated with infliximab throughout her pregnancy. Her baby was born healthy and received a Bacillus Calmette-Guérin (BCG) vaccine aged 3 months. Soon after this the infant became unwell and died aged 4.5 months. At post-morte...
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PMID: 21122568
PDF is available here.
Abstract
To determine the underlying risk factors in early pregnancy complications and outcome.
Case series.
This study was conducted at the Department of Obstetrics and Gynaecology Unit-IV, Liaquat University of Medical and Health Sciences, Jamshoro, from July 2007 to June 2008.
All the women with first tri...
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PMID: 21078248
PDF is available here.
Abstract
To examine the frequency of adverse outcome during pregnancy and delivery and neonatal complications among normal weight, overweight and obese women at the beginning of pregnancy.
The study is a retrospective cohort study of 600 women, divided in 3 groups on the basis of maternal body mass index (BM...
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PMID: 21081792
PDF is available here.
Tiki Bakhshi,
Mark B Landon,
Yinglei Lai,
Catherine Y Spong,
Dwight J Rouse,
Kenneth J Leveno,
Michael W Varner,
Steve N Caritis,
Paul J Meis,
Ronald J Wapner,
Yoram Sorokin,
Menachem Miodovnik,
Marshall Carpenter,
Alan M Peaceman,
Mary J O'Sullivan,
Baha M Sibai,
Oded Langer,
John M Thorp and
Brian M Mercer
Abstract
We compared maternal and neonatal outcomes following repeat cesarean delivery (CD) of women with a prior classical CD with those with a prior low transverse CD. The Maternal Fetal Medicine Units Network Cesarean Delivery Registry was used to identify women with one previous CD who underwent an elect...
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PMID: 20458666
PDF is available here.
Abstract
Transient tachypnea of the newborn (TTN) is a common respiratory problem in newborns. This study aims to determine if cesarean delivery (CD) is a risk factor for TTN, and if labor prior to CD decreases this risk. A linked data set consisting of Arizona birth certificates (1994 to 1998) and infants e...
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PMID: 20486067
PDF is available here.
Abstract
We report six cases of OTC deficiency during pregnancy managed at our institution and review the literature on OTC deficiency during pregnancy. Using the patient database from our Metabolic Clinic, pregnant OTC deficiency carriers were identified. The antenatal, intrapartum, and postpartum periods w...
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PMID: 20458665
PDF is available here.
Abstract
About 11% of pregnant women suffer from a major depression requiring treatment. If left untreated, there are specific risks such as preterm delivery or low birth weight. The initial difficulty lies in diagnosing the depression itself, since many depressive symptoms are falsely ascribed to the pregna...
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PMID: 21043017
PDF is available here.
Abstract
We analysed data obtained from the Northern Finnish Birth Cohort Study conducted in 1966, in which, data on mothers and offspring from pregnancy through to the age of 31 years were collected. The cohort comprised 11 656 individuals born from singleton births (51 % males and 49 % females). Materna...
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PMID: 20522275
PDF is available here.
Abstract
We compared 15,136 gestations born late preterm with 170,593 deliveries between 37 0/7 and 41 6/7 weeks. We defined the following categories of precursors for late preterm delivery: "spontaneous labor," "premature rupture of the membranes (preterm PROM)," "indicated" delivery, and "unknown." Inciden...
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PMID: 20966688
PDF is available here.
Abstract
To estimate the prevalence of major and minor depression, panic disorder, and suicidal ideation during pregnancy while also identifying factors independently associated with antenatal depressive disorders.
In this prospective study, participants were 1,888 women receiving ongoing prenatal care at a...
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PMID: 20966690
PDF is available here.
Abstract
The recent application of concepts of evolution to human disease is proving useful to understand certain pathophysiological mechanisms of different entities that span genomic alterations of immunity, respiratory and hormone function, and the circulatory and neural systems. However, e...
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PMID: 20675202
PDF is available here.
Abstract
We analyzed the association of two adiponectin single-nucleotide polymorphisms (SNPs) with preeclampsia. One hundred eighty-eight Han Chinese pregnant women were enrolled (81 normal-term, 20 mild preeclampsia and 87 severe cases). Serum adiponectin level, and adiponectin exon 2 SNP +45T/G (rs2241766...
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PMID: 20664545
PDF is available here.
Abstract
Vulvar edema is associated with a variety of conditions. The edema can result from inflammatory conditions, infections, infestations, trauma, pregnancy, tumors and iatrogenic causes. At times, it is difficult to determine the cause of the vulvar edema. Treatment consists of determining the origin of...
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PMID: 20883919
PDF is available here.
Abstract
Over half (55%) of pregnant women with abnormalities suggestive of autoimmune thyroiditis and/or hypothyroidism would be missed if only those with high-risk criteria were examined. A more extensive screening of thyroid autoimmunity and dysfunction seems warranted....
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PMID: 20682632
PDF is available here.
Abstract
Inflammatory Bowel Diseases (IBD) affect mainly younger people. Biologic therapies are safe and effective in inducing and maintain remission in that patients. We reviewed herein the current knowledge about the safety and the effectiveness of biologic therapies in managing pregnant IBD patients.
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PMID: 21137576
PDF is available here.
Abstract
Concerns have been expressed about possible adverse effects of the use of antidepressant medication during pregnancy, including risk for neonatal pathology and the presence of congenital malformations.
Data from the Swedish Medical Birth Register (MBR) from 1 July 1995 up to 2007 were used to identi...
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PMID: 20047705
PDF is available here.
Abstract
To report the clinical course of four women treated with intravitreal bevacizumab during pregnancy.
Observational case series.
Four pregnant women were treated with intravitreal bevacizumab for choroidal neovascularization (CNV) because of presumed ocular histoplasmosis syndrome punctate inner choro...
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PMID: 20924262
PDF is available here.
Abstract
We explore the origins of the current preoccupation with risk. Using Pickstone's historical phases of modern health care, the paper explores the way maternity services changed from a social to a medical model over the twentieth century and suggests that the risk agenda was part of this process.
Curr...
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PMID: 20719418
PDF is available here.
Abstract
near-miss case reviews are one of a number of audit approaches currently being used and evaluated by those with an interest in reducing high rates of maternal mortality in developing countries. Researchers are beginning to take an interest in issues relating to the sustainability of audits.
to devel...
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PMID: 20709433
PDF is available here.
Abstract
We used the defined cutoff values in determining vitamins D, A, and E deficiency. The prevalence of vitamin D deficiency was 95.8%, vitamin A was 7%, and vitamin E was 58.6%. The correlation coefficient between serum vitamin D and vitamin E shows an inverse relationship (r=0.24, p=0.004).
Extent vit...
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PMID: 20953527
PDF is available here.