Abstract
Dementia is associated with increased rates and often poorer outcomes of hospitalization, including worsening cognitive status. New evidence is needed to determine whether some admissions of persons with dementia might be potentially preventable.
To determine whether...
|
PMID: 22235087
PDF is available here.
Abstract
Clinical practice guidelines recommend maintaining serum potassium levels between 4.0 and 5.0 mEq/L in patients with acute myocardial infarction (AMI). These guidelines are based on small studies that associated low potassium levels with ventricular arrhythmias in the pre-β-blocker...
|
PMID: 22235086
PDF is available here.
Abstract
We present the first analysis of age-at-onset in the NIMH LOAD sample that allows for both a multilocus trait model and genetic heterogeneity among the contributing sites, while at the same time accommodating age censoring, effects of known genetic covariates, and full pedigree and marker informatio...
|
PMID: 21812099
PDF is available here.
Eric A Engels,
Ruth M Pfeiffer,
Joseph F Fraumeni,
Bertram L Kasiske,
Ajay K Israni,
Jon J Snyder,
Robert A Wolfe,
Nathan P Goodrich,
A Rana Bayakly,
Christina A Clarke,
Glenn Copeland,
Jack L Finch,
Mary Lou Fleissner,
Marc T Goodman,
Amy Kahn,
Lori Koch,
Charles F Lynch,
Margaret M Madeleine,
Karen Pawlish,
Chandrika Rao,
Melanie A Williams,
David Castenson,
Michael Curry,
Ruth Parsons,
Gregory Fant and
Monica Lin
Abstract
Solid organ transplant recipients have elevated cancer risk due to immunosuppression and oncogenic viral infections. Because most prior research has concerned kidney recipients, large studies that include recipients of differing organs can inform cancer etiology.
To d...
|
PMID: 22045767
PDF is available here.
Cynthia C Cardoso,
Ana Carla Pereira,
Vânia N Brito-de-Souza,
Sandra M B Duraes,
Marcelo Ribeiro-Alves,
José Augusto C Nery,
Ângela S Francio,
Patrícia R Vanderborght,
Francisco P C Parelli,
Andrea Alter,
Jorge Luís Salgado,
Elizabeth P Sampaio,
Adalberto R Santos,
Maria Leide W R Oliveira,
Euzenir N Sarno,
Erwin Schurr,
Marcelo T Mira,
Antonio G Pacheco and
Milton O Moraes
Abstract
We first conducted 4 association studies (2639 individuals) that showed a protective effect of the -308A allele (odds ratio [OR] = 0.77; P = .005). Next, results of a meta-analysis reinforced this association after inclusion of our new data (OR = 0.74; P = .04). Furthermore, a subgroup analysis incl...
|
PMID: 21917899
PDF is available here.
Abstract
We assessed RV5 coverage and diarrhea-associated health care use from July 2007 through June 2009 versus July 2001 through June 2006 in children under 5 years of age. We compared the rates of diarrhea-associated health care use in unvaccinated children in the period from January through June (when r...
|
PMID: 21992123
PDF is available here.
Abstract
We hypothesized that a long interdialytic interval is associated with adverse events in patients receiving hemodialysis.
We studied 32,065 participants in the End-Stage Renal Disease Clinical Performance Measures Project, a nationally representative sample of U.S. patients receiving...
|
PMID: 21992122
PDF is available here.
David J Thurman,
Ettore Beghi,
Charles E Begley,
Anne T Berg,
Jeffrey R Buchhalter,
Ding Ding,
Dale C Hesdorffer,
W Allen Hauser,
Lewis Kazis,
Rosemarie Kobau,
Barbara Kroner,
David Labiner,
Kore Liow,
Giancarlo Logroscino,
Marco T Medina,
Charles R Newton,
Karen Parko,
Angelia Paschal,
Pierre-Marie Preux,
Josemir W Sander,
Anbesaw Selassie,
William Theodore,
Torbjörn Tomson and
Samuel Wiebe
Abstract
We discuss: (1) conceptual and operational definitions of epilepsy, (2) data resources and recommended data elements, and (3) methods and analyses appropriate for epidemiologic studies or the surveillance of epilepsy. Variations in these are considered, taking into account differing resource availab...
|
PMID: 21899536
PDF is available here.
Abstract
We hypothesized that ESRD patients with relative thrombocytosis (platelet count >300 × 10(3)/μL) have a higher mortality rate and that this association may be related to malnutrition-inflammation cachexia syndrome (MICS).
We examined the associations of 3-mo-averaged platelet count...
|
PMID: 21813809
PDF is available here.
Abstract
We propose a practical risk stratification system highly predictive of long-term survival outcomes after OLT using DCD grafts. Application of this predictive index for transplant candidates receiving DCD liver grafts would improve patients' outcomes and optimize use of scarce resources....
|
PMID: 21930997
PDF is available here.
Abstract
Erectile dysfunction (ED) is associated with cardiovascular disease (CVD) because it is highly prevalent among those with cardiovascular risk factors (CVRFs). Moreover, it precedes the development of CVD and is considered a subrogate marker of subclinical CVD.
The aim...
|
PMID: 21699670
PDF is available here.
Abstract
We will use the term "refractory" LN, for those cases with none or partial response to first-line therapies. In this sense, numerous epidemiological factors, including racial, socioeconomic, histological and serological parameters, may influence treatment response and, therefore, may have an impact...
|
PMID: 21565286
PDF is available here.
Abstract
Hypertension is found in more than 50% of pediatric patients with CKD. However, its prevalence varies according to the cause of CKD. It is relatively infrequent in children with structural disorders. Acquired renal disorders are associated with an increased prevalence of hypertension...
|
PMID: 21896377
PDF is available here.
Abstract
To determine prevalence and risk factors for hypertension and isolated office hypertension diagnosed by ambulatory blood pressure monitoring in HIV-infected patients.
Cross-sectional study of 310 patients. A 24-hour ambulatory blood pressure monitoring procedure was p...
|
PMID: 21654497
PDF is available here.
Giselle Guerra,
Gaetano Ciancio,
Jeffrey J Gaynor,
Alberto Zarak,
Randolph Brown,
Lois Hanson,
Junichiro Sageshima,
David Roth,
Linda Chen,
Warren Kupin,
Lissett Tueros,
Phillip Ruiz,
Alan S Livingstone and
George W Burke
Abstract
We conducted a randomized trial involving 150 kidney transplant recipients to compare tacrolimus/sirolimus, tacrolimus/mycophenolate mofetil (MMF), and cyclosporine/sirolimus. All patients received daclizumab induction and maintenance corticosteroids. Median follow-up was 8 yr post-transplant. Acute...
|
PMID: 21807891
PDF is available here.
Abstract
Hepatitis belongs to a group of diseases caused by different hepatotropic viruses, which are responsible for inflamation of the liver. The most common form of liver infection is hepatitis B virus (HBV). It is transmitted by blood and other body fluids. The infection can also occur du...
|
PMID: 21991844
PDF is available here.
Abstract
Influenza is one of the most common diseases in the world. It occurs seasonally and is a viral disease contracted by a direct contact (respiratory droplets), causing many serious complications. The best way to prevent influenza is to get vaccinated once a year, which is the cheapest...
|
PMID: 21991845
PDF is available here.
Abstract
Sexual dysfunction in patients diagnosed with depressive disorders affect all phases of sexual response: a decline in libido, erectile dysfunction, ejaculation disorders in men and orgasm and menstruation in women. It is estimated that are present in approximately 70% of patients, af...
|
PMID: 21991854
PDF is available here.
Abstract
This article aims to examine data on Psychiatric diagnoses among deaf people in comparison with hearing people in the psychiatric hospital in Beau-Vallon.
This work proposes to study the diagnostic data from the Summary Psychiatric Minimum (Résumé psychiatrique mini...
|
PMID: 21894115
PDF is available here.
Abstract
We conclude that HPs and SSA/Ps in Korean patients share some, but not all, clinical and molecular characteristics to those that occur in Americans. The data support the theory that the right and left colon are biologically different with regard to susceptibility to serrated cancer, and that anatomi...
|
PMID: 21836485
PDF is available here.
Abstract
Despite advances in the management of cardiovascular diseases, the incidence of cardiovascular diseases is increasing both in developed and developing world. This phenomenon is associated with the worldwide pandemic of obesity and type 2 diabetes; both are related to the life style o...
|
PMID: 21835741
PDF is available here.
Holly M Biggs,
Duy M Bui,
Renee L Galloway,
Robyn A Stoddard,
Sean V Shadomy,
Anne B Morrissey,
John A Bartlett,
Jecinta J Onyango,
Venance P Maro,
Grace D Kinabo,
Wilbrod Saganda and
John A Crump
Abstract
We enrolled consecutive febrile admissions to two hospitals in Moshi, Tanzania. Confirmed leptospirosis was defined as a ≥ 4-fold increase in microscopic agglutination test (MAT) titer; probable leptospirosis as reciprocal MAT titer ≥ 800; and exposure to pathogenic leptospires as titer ≥ 100....
|
PMID: 21813847
PDF is available here.
Abstract
Type 2 diabetes has long been recognized as an independent risk factor for cardiovascular disease (CVD), including coronary artery disease (CAD), stroke, peripheral arterial disease, cardiomyopathy, and congestive heart failure. Cardiovascular (CV) complications are the leading cause...
|
PMID: 21802578
PDF is available here.
Abstract
Major depressive disorder, the most common psychiatric illness, is often chronic and a major cause of disability. Many patients with major depressive episodes who have an underlying but unrecognized bipolar disorder receive pharmacologic treatment with ineffective regimens that do no...
|
PMID: 21810644
PDF is available here.
Suyang Hao,
Thomas W Smith,
Peigou G Chu,
Qin Liu,
Chi Young Ok,
Bruce A Woda,
Di Lu,
Pei Lin,
Sa A Wang,
Karen Dresser,
Kenneth L Rock and
Zhong Jiang
Abstract
We have found that IMP3, an oncofetal RNA-binding protein, is a biomarker to predict aggressive tumors.
To investigate whether IMP3 can be used as a new biomarker to predict the recurrence and overall survival of patients with meningiomas.
One hundred seven patients w...
|
PMID: 21809995
PDF is available here.
Abstract
To assess the prevalence of diabetes and diabetic retinopathy in indigenous Australians aged ≥40 years.
The National Indigenous Eye Health Survey used a stratified, multistage cluster probability sampling frame to provide a representative sample of the indigenous Au...
|
PMID: 21819502
PDF is available here.
Abstract
To validate the accuracy of clinical ophthalmic information held on the West Australian blind register.
Community-based cross-sectional study.
Legally blind or severely vision-impaired people were selected randomly from the Association for the Blind of...
|
PMID: 21819503
PDF is available here.
Abstract
There has been an increase in the number of foreign-born tuberculosis (TB) patients residing in Japan. The purpose of this study is to clarify the clinical features of the foreign-born TB patients treated at our hospital.
|
PMID: 21922779
PDF is available here.
Abstract
Annual reports of tuberculosis (TB) statistics have been compiled using a database built through the nationwide computerized TB surveillance system in Japan. Using the annual report database for 2007-2009, this study compared the drug resistance rates among eight geographical districts. The proportio...
|
PMID: 21922783
PDF is available here.
Abstract
Various early arthritis clinics have provided extensive data on presentation, disease course and outcomes of early inflammatory arthritis (EIA). The present Review summarizes the epidemiological data from these early arthritis cohorts (EACs), which provide information about the frequ...
|
PMID: 21670767
PDF is available here.
Katherine H Ingram,
Cristina Lara-Castro,
Barbara A Gower,
Robert Makowsky,
David B Allison,
Bradley R Newcomer,
A Julian Munoz,
T Mark Beasley,
Jeannine C Lawrence,
Robert Lopez-Ben,
Dana Y Rigsby and
W Timothy Garvey
Abstract
We have examined in a cross-sectional study the interrelationships among IMCL, insulin sensitivity, and adiposity in European Americans (EAs) and African Americans (AAs). In 43 EA and 43 AA subjects, we measured soleus IMCL content with proton-magnetic resonance spectroscopy, insulin sensitivity wit...
|
PMID: 21436797
PDF is available here.
Abstract
Highly active antiretroviral therapy (HAART) use has markedly reduced AIDS-related mortality and opportunistic illness. With improved survival, cardiovascular disease (CVD) has emerged as an important noninfectious chronic comorbidity among antiretroviral (ARV)-treated HIV-infected p...
|
PMID: 21546831
PDF is available here.
Abstract
We characterized levels of acute-phase reactants (C-reactive protein (CRP), interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α), white blood cell (WBC) count), adhesion molecules (E-selectin, vascular cell adhesion molecule-1), and coagulation products (fibrinogen, plasminogen activator inhibito...
|
PMID: 21233809
PDF is available here.
Abstract
We measured the frequency of perceived stigma and discrimination among caregivers of veterans with TBI and examined whether perceived stigma and discrimination are associated with caregiver strain, social isolation, depression, and anxiety.
Seventy caregivers of veterans with TBI com...
|
PMID: 21723524
PDF is available here.