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Heterocyclic Compounds, Bridged-Ring (5):
Recent article
Heterocyclic Compounds, Bridged-Ring
Journal of Hazardous Materials (178)1-3 2010
Abstract
This work reports the electrocatalysis of bisphenol A on Ni(II) tetraamino metallophthalocyanine (NiTAPc) polymer modified gold electrode containing Ni-O-Ni bridges (represented as Ni(OH)TAPc). The Ni(II)TAPc films were electro-transformed in 0.1 mol L(-1) NaOH aqueous solution to form 'O-Ni-O oxo b...
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PMID: 20122800
PDF is available here.
PDF is available here.
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Abstract
Total syntheses of (+)-nankakurine A (2) and (+)-nankakurine B (3) were accomplished by a sequence that employs an intramolecular dipolar cycloaddition of an azomethine imine intermediate to form the azatricyclic moiety and establish the relative configuration of the spiropiperidine ring. These synth...
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PMID: 18680252
PDF is available here.
PDF is available here.
Abstract
Organic Letters (10)12 2008
Abstract
Cyclic sulfonyl hydrazine was demonstrated for the first time as a new functionality for organocatalysis. A series of six-membered cyclic hydrazines derived from camphor sulfonic acid were synthesized. With trichloroacetic acid as cocatalyst, they are efficient organocatalysts for enantioselective D...
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PMID: 18481866
PDF is available here.
PDF is available here.
Abstract
A series of copper(I) complexes with a sterically hindered, bidentate ligand, BL iPr, derived from an N-heterocyclic carbene precursor have been isolated, characterized and their reactivity studied. The ethylene-bridged bis(imidazolin-2-imine) ligand (BL iPr) provides strongly donating N-donor atoms...
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PMID: 18259621
PDF is available here.
PDF is available here.
Journal of Natural Products (70)12 2007
Abstract
Three new Securinega alkaloids, secu'amamines B-D ( 1- 3), were isolated from the wood of the Japanese medicinal plant Securinega suffruticosa var. amamiensis, together with five known analogues ( 4, 6- 9). The structures 1- 3 were elucidated by spectroscopic methods including 2D NMR, and all eight...
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PMID: 18052029
PDF is available here.
PDF is available here.
Abstract
These results supported strongly the participation of an intramolecular pi-pi interaction between the two indolizine rings in these molecules and, hence, of a particular gauche (cis) conformation. However, the conformational considerations and molecular calculations (Mopac PM3) for some bis(indolizi...
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PMID: 17917289
PDF is available here.
PDF is available here.
Abstract
We discovered a microbial fermentation extract that exhibited in vivo anticoccidial activity. Fractionation of this extract led to the discovery of two potent antiprotozoals, emecorrugatin A (1) and coccidiostatin A (2). The former compound exhibited only in vitro activity, whereas the latter new co...
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PMID: 17636951
PDF is available here.
PDF is available here.
Abstract
A series of exceptionally potent agonists at neuronal nicotinic acetylcholine receptors (nAChRs) has been investigated. Several N-(3-pyridinyl) derivatives of bridged bicyclic diamines exhibit double-digit-picomolar binding affinities for the alpha 4 beta 2 subtype, placing them with epibatidine amo...
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PMID: 17585748
PDF is available here.
PDF is available here.
Abstract
Abstract
Journal of Natural Products (69)12 2006
Abstract
A ureido Diels-Alder adduct of sorbicillinol 3 has been isolated from an intertidal marine Paecilomyces marquandii strain, in a screening for new natural products. The structure was determined by spectroscopic methods, and the relative stereochemistry was confirmed by molecular modeling. The absolut...
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PMID: 17190466
PDF is available here.
PDF is available here.
Abstract
The cobalt-catalyzed [6+2] cycloaddition of cyclooctatetraene 1 with alkynes 3 affords monosubstituted bicyclo[4.2.2]deca-2,4,7,9-tetraenes 4 in fair to good yields. Due to the valence tautomerism, 1,3,5-cyclooctatriene 2, in equilibrium with bicyclo[4.2.0]octa-2,4-diene A, and alkynes 3 are convert...
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PMID: 16555854
PDF is available here.
PDF is available here.
Abstract
A series of amino derivatives of 10-(diphenylmethylene)-4-azatricyclo[5.2.1.0(2.6)]dec-8-ene-3,5-dione, analogues of chlorpromazine and aminoperazine have been prepared. These compounds are expected to have antipsychotic and/or anti HIV activity. Molecular structure of III was confirmed by an X-ray...
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PMID: 17203861
PDF is available here.
PDF is available here.
Abstract
A series of aminoalkanol derivatives of 10-(diphenylmethylene)-4-azatricyclo[5.2.1.0(2.6)]dec-8-ene-3,5-dione and 4-hydroxy-4-azatricyclo[5.2.1.0(2,6)]dec-8-ene-3,5-dione have been prepared. The pharmacological profile of selected compounds was evaluated for their affinities at beta-adrenoceptors. T...
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PMID: 17438864
PDF is available here.
PDF is available here.
Abstract
Photophysical studies with semi-rigid, 1, and flexible, 2, donor-bridge-acceptor (D-b-A2+) molecules with D a porphyrin and A2+ a methyl viologen moiety, were performed in neat polar solvents as well as included in surfactant (DTAB) aqueous and in reverse AOT/n-alkane micelles. The micelles acted as...
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PMID: 16474876
PDF is available here.
PDF is available here.
Organic Letters (7)24 2005
Abstract
[reaction: see text] The ABC ring system of the natural product calyciphylline A has been synthesized. The key steps were a palladium-catalyzed intramolecular coupling of an amino-tethered vinyl bromide with a ketone using potassium phenoxide as the base to generate the C-ring and a hydroxyl-directe...
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PMID: 16288531
PDF is available here.
PDF is available here.
Abstract
Two compounds were isolated and identified as: 13-dehydro-1beta-acetyl-2alpha,6beta-dihydroxyhetisine (I) and Guanfu base G (II). CONCLUSION: Compound I is a new alkaloid....
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PMID: 16196272
PDF is available here.
PDF is available here.
Abstract
Crystals of a novel platinum(II) complex with squarato ligand, [Pt(3)(mu(2)-C(4)O(4))(3)(H(2)NPr(i))(6)].3H(2)O (1) (H(2)NPr(i)=ipa), have been isolated from the aqueous solution of cis-[Pt(H(2)O)(2)(H(2)NPr(i))(2)]SO(4) and barium squarate. Slow evaporation of methanol solution of cis-[Pt(NO(3))(2)...
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PMID: 15927264
PDF is available here.
PDF is available here.
Acta Crystallographica Section B (61)Pt 3 2005
Abstract
The homologous series of three-atom bridged biaryls comprising 5,7-dihydro-1,2,3,9,10,11-hexamethoxydibenzo[c,e]oxepine, 6,7-dihydro-1,2,3,9,10,11-hexamethoxy-6-methyl-5H-dibenzo[c,e]azepinium chloride, 5,7-dihydro-1,2,3,9,10,11-hexamethoxydibenzo[c,e]thiepine, and the 6-oxide and 6,6-dioxide deriva...
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PMID: 15914899
PDF is available here.
PDF is available here.
Abstract
We designed and synthesized ABC-ring 6 and CDEFG-ring 7, which are truncated analogues of the northern and southern hemispheres of zoanthenol 5, respectively, and which incorporate all of the functionality of each hemisphere. A preliminary SAR study suggested that the hydrochloride of the CEFG-ring...
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PMID: 15109670
PDF is available here.
PDF is available here.
Abstract
The bis(phosphatediester)-bridged complexes [[Ni([12]aneN(3))(mu-O(2)P(OR)(2))](2)](PF(6))(2) [[12]aneN(3)=Me(3)[12]aneN(3), 2,4,4-trimethyl-1,5,9-triazacyclododec-1-ene; R=Me (1), Bu (2), Ph (3), Ph-4-NO(2) (4); [12]aneN(3)=Me(4)[12]aneN(3), 2,4,4,9-tetramethyl-1,5,9-triazacyclododec-1-ene; R=Me (5...
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PMID: 15054761
PDF is available here.
PDF is available here.
Abstract
Nonstabilized azomethine ylides (i.e. those bearing only hydrogens or alkyl groups) can be generated from (2-azaallyl)stannanes and (2-azaallyl)silanes through an intramolecular N-alkylation/demetalation cascade. The resulting ylides undergo [3+2] cycloaddition with electron-poor or electron-rich di...
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PMID: 15058937
PDF is available here.
PDF is available here.
Abstract
2-Azaallyllithium species [R(1)CH(-)N=C(X)R(2)Li(+), where R(1) and R(2) are alkyl and X = OMe] were generated by tin-lithium exchange of (2-azaallyl)stannanes and underwent [pi4s+pi2s] and [pi6s+pi4s] cycloadditions with cyclic dienes and trienes, respectively, to generate novel bridged azabicyclic...
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PMID: 14961676
PDF is available here.
PDF is available here.
Abstract
The low-temperature reaction of MeSiCl3 with 2-Li-C5H4N (1:3 equivalents) in thf gives [MeSi(2-C5H4N)3LiX](X = 0.2Br, 0.8Cl), containing the first example of a Si-bridged tris(pyridyl) ligand.
Copyright 2004 The Royal Society of Chemistry
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PMID: 15252539
PDF is available here.
PDF is available here.
Journal of Organic Chemistry (68)21 2003
Abstract
A new class of tandem [4+2]/[3+2] cycloadditions of nitroalkenes is described in which both pericyclic processes are intramolecular. Two subclasses of intra [4+2]/intra [3+2] cycloadditions have been explored in which the dipolarophile is tethered at either C(5) or C(6) of the nitronate. For both fa...
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PMID: 14535778
PDF is available here.
PDF is available here.
Abstract
The synthesis and spectroscopic characterization of the mononuclear uranium complex [((ArO)(3)tacn)U(III)(NCCH(3))] is reported. The uranium(III) complex reacts with organic azides to yield uranium(IV) azido as well as uranium(V) imido complexes, [((ArO)(3)tacn)U(IV)(N(3))] and [((ArO)(3)tacn)U(V)(N...
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PMID: 12683828
PDF is available here.
PDF is available here.
Phytochemistry (62)4 2003
Abstract
Five oleanane-type pentacyclic triterpenoids were isolated by chromatographic separation of a chloroform extract of the stem bark of Embelia schimperi. Three of these compounds have a methyleneoxy bridge. Two compounds, embelinone and schimperinone, are reported here for the first time from a natura...
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PMID: 12560028
PDF is available here.
PDF is available here.
Journal of Organic Chemistry (67)24 2002
Abstract
Treatment of molybdenum Fischer carbene complexes with 6-methylene-7-octen-1-yne derivatives at 40 degrees C generates substituted tricyclo[4.3.1.0(1,6)]deca-2,4-dienes in good yield. Pentacarbonyl(butylmethoxycarbene)molybdenum(0) afforded the highest cyclization yields (54%), while the analogous c...
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PMID: 12444658
PDF is available here.
PDF is available here.
Journal of Organic Chemistry (67)23 2002
Abstract
Investigations and stereoselective studies on the tandem reactions of carbonyl ylides generated from alpha-diazo ketones in the presence of carbonyl compounds are presented in this paper. Intramolecular cyclization of rhodium carbenoids generated the transient five- or six-membered-ring carbonyl yli...
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PMID: 12423129
PDF is available here.
PDF is available here.
Abstract
The synthesis and biological testing of a novel series of nonpeptide vasopressin receptor antagonists, containing a bridged bicyclic nucleus, are reported. Variation of substituents (R(1)-R(3)) in general formula 3, and the configuration of the stereocenter, resulted in potent V(2)-selective (e.g.,...
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PMID: 12372506
PDF is available here.
PDF is available here.
Journal of Organic Chemistry (67)15 2002
Abstract
A 10-membered heterocyclic ring system 1,3,8-trisubstituted 2,5,7-trioxo-1,4,8-triazadecane that represents a Ni-to-Ni+ 3-ethylene-bridged partially modified retro-inverso tetrapeptide beta-turn mimetic (EBRIT-BTM) has been designed, synthesized, and structurally analyzed. These compounds utilize an...
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PMID: 12126392
PDF is available here.
PDF is available here.
Abstract
A new class of Mo/Fe/S clusters with the MoFe(3)S(3) core has been synthesized in attempts to model the FeMo-cofactor in nitrogenase. These clusters are obtained in reactions of the (Cl(4)-cat)(2)Mo(2)Fe(6)S(8)(PR(3))(6) [R = Et (I), (n)Pr (II)] clusters with CO. The new clusters include those preli...
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PMID: 11782173
PDF is available here.
PDF is available here.
Journal of Organic Chemistry (66)23 2001
Abstract
Abstract
New compounds having two indolizine nuclei in a molecule were prepared in low to moderate yields from the reactions of potassium 2-indolizinethiolates with 1,omega-dihalides such as 1,2-diiodoethane, 1,3-dibromopropane, 1,4-dibromobutane, alpha,alpha'-dichloro-o-xylene, and alpha,alpha'-dichloro-p-x...
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PMID: 11724229
PDF is available here.
PDF is available here.
Journal of Organic Chemistry (66)21 2001
Abstract
Journal of Organic Chemistry (66)21 2001
Abstract
Abstract
Series of dinuclear species [Ru(2)(L)(2)(LH)(2)-mu-S(2)Cl(2)], [Ru(2)(L)(2)(LH)(4)-mu-Se(2)Cl(2)] (L=L(1)H and L(3)H) and [Ru(2)(L(2))(2)(L(2)H)-mu-Se(2)Cl(2)].2H(2)O, where L(1)H, L(2)H and L(3)H represent for 2-mercapto-5-phenyl-1,3,4-oxadiazole, 2-mercapto-benzimidazole and 2-mercapto-benzothiazo...
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PMID: 11566330
PDF is available here.
PDF is available here.
Phytochemistry (57)8 2001
Abstract
Three quassinoids, iandonosides A and B and iandonone, were isolated from the root of Eurycoma harmandiana, along with five known quassinoids, casteloside B, 13 beta, 21-dihydroeurycomanone, chaparrinone, glaucarubolone and ailanquassin B as well as the coumarin, scopoletin. The structural elucidati...
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PMID: 11454344
PDF is available here.
PDF is available here.
Abstract
A series of analogues related to 1-[2-(diphenylmethoxy)ethyl]-4-(3-phenylpropyl)piperazine (2) and 1-¿2-[bis(4-fluorophenyl)methoxy]ethyl¿-4-(3-phenylpropyl)piperazine (3) (GBR 12935 and GBR 12909, respectively), in which the piperazine moiety was replaced by bridged piperazines for structural rig...
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PMID: 11123994
PDF is available here.
PDF is available here.
Abstract
A molecular dynamics study of chloride capture from water by the tetraprotonated cryptand SC24 is presented. The system under study consisted of a cryptand molecule, chloride ion, and 319 water molecules. Calculations were performed for 19 distances between the cryptand and the chloride. For each...
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PMID: 11542140
PDF is available here.
PDF is available here.
Abstract
The capture of chloride from water by the tetraprotonated form of the spherical macrotricyclic molecule SC24 was studied using molecular dynamics simulation methods. This model ionophore represents a broad class of molecules which remove ions from water. Two binding sites for the chloride were fou...
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PMID: 11542142
PDF is available here.
PDF is available here.