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Blood Group Incompatibility (2):
Recent article
Blood Group Incompatibility
Abstract
We conclude that Foxp3(+) cells are needed to maintain acceptance of major histocompatibility complex-incompatible renal allografts in the first 3 months after transplantation and may act by inhibiting DC maturation.
Copyright © 2011 American Society for Investigative Pathology. Pub...
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PMID: 21435448
PDF is available here.
PDF is available here.
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The Journal of the Louisiana State Medical Society : official organ of the Louisiana State Medical Society (163)2 2011
Abstract
We were able to facilitate three recipients getting transplanted. We discuss the formulation of this unique program, the choosing of potential donor/recipient pairs and outcomes. A review of the controversies of paired kidney donation is also presented....
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PMID: 21667804
PDF is available here.
PDF is available here.
Abstract
We have been using selective immunoadsorption in the two ABO-incompatible kidney transplants performed in our institution. No acute rejection was experienced at 6 and 26 month follow-up and both grafts are functioning well. Despite the ABO-incompatible kidney transplant widespread use, the best dese...
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PMID: 21834478
PDF is available here.
PDF is available here.
The practising midwife (13)11 2010
Abstract
Abstract
Survival following cardiac transplantation in infancy has improved substantially. There is a growing shortage of donors, the impact of which may be offset by increase in ABO-incompatible transplants, size-mismatching and mechanical support. The authors reviewed their results and outcomes following i...
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PMID: 20656734
PDF is available here.
PDF is available here.
Abstract
The LCM-positive LDLT recipients showed significantly poorer outcomes than the LCM-negative recipients. Among the LCM-positive recipients, 44.1% of recipients eventually died and 85.2% of recipients revealed positive C4d findings. The survival rate of LCM-positive and ABO-incompatible group was 0.50...
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PMID: 20096431
PDF is available here.
PDF is available here.
Abstract
With technical advancement, we have been able to reconstruct both HAs in most cases without any HA-related complications, despite the fact that complex HA reconstructions were needed. Group 3 patients had a significantly greater incidence of anastomotic biliary stricture, which was decreased by dual...
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PMID: 19758670
PDF is available here.
PDF is available here.
MMW Fortschritte der Medizin (152)20 2010
Abstract
Abstract
One thousand and ninety-two children were included. Newborns of A, B or AB group delivered from a mother 0 were at increased risk of presenting severe hyperbilirubinemia (OR=2.35 [1.22-4.52]). The negative predictive value was 96%. Yet, the determination of the Coombs test does not increase NPV. CON...
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PMID: 20338695
PDF is available here.
PDF is available here.
Abstract
The 60th anniversary of Israel coincides with the advent of the first hemodialysis in the Middle East. It was performed by Dr. Kurt Steinitz--a Jewish immigrant from Breslau, then in Germany. After spending 9 years at the Istanbul Faculty of Medicine as a clinical biochemist, Steinitz became the dir...
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PMID: 20549930
PDF is available here.
PDF is available here.
Connecticut medicine (74)2 2010
Abstract
We report a patient with myelodysplasia who was noted to have a febrile response to a unit of red blood cells (RBCs). Testing of the posttransfusion specimen raised concerns for a hemolytic transfusion reaction when the patient's RBCs demonstrated a positive direct antiglobulin test (DAT) and the pl...
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PMID: 20218043
PDF is available here.
PDF is available here.
Transfusion (50)2 2010
Abstract
Since the first issue of TRANSFUSION in 1961, there has been a tremendous expansion in not only the number of blood group antigens identified but also in our knowledge of their biochemical basis, function, and more recently, associated DNA changes. As certain techniques became availa...
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PMID: 19906040
PDF is available here.
PDF is available here.
Abstract
Medium age of donors and recipients were 47.8 +/- 12.4 and 44.4 +/- 14.1 years, respectively. 90% of donors were females and 73% of recipients males. Follow-up time was 10.2 +/- 10.2 months. Siblings and spouses were the most frequent relation (n=4, 36.4%, respectively). Chronic glomerulonephritis,...
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PMID: 20038970
PDF is available here.
PDF is available here.
Abstract
Abstract
Abstract
We describe the fate of all patients that were enrolled in our program during 2004-2010.
Data on registration, computerized matching, cross matching, and transplantations within or outside the program were collected.
Between January 2004 and December 2010, 422 pairs w...
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PMID: 21696050
PDF is available here.
PDF is available here.
Abstract
Exchange donor programs and desensitization protocols are available options for ABO-incompatible and positive cross-match living donor kidney transplantations. Patient and donor blood types, the degree of sensitization, and DSA titers should be considered to achieve successful kidney...
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PMID: 21698836
PDF is available here.
PDF is available here.
Abstract
We observed that fetal growth was mildly restricted and the peak systolic velocity of the fetal middle cerebral artery (PSV-MCA) was above the upper limit of the reference range (1.55 multiples of the median). Amniocentesis was also carried out and the DeltaOD450 value was in the lower mid-zone of t...
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PMID: 19923849
PDF is available here.
PDF is available here.
Abstract
Abstract
The authors studied materials of 17 complications due to transfusion of erythrocytes incompatible by AB0 phenotype, developed during 25 years in clinics of the Stavropol krai. All complications were associated with concrete defects in the work of blood service: wrong organization of blood service ma...
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PMID: 20552793
PDF is available here.
PDF is available here.
Transfusion (50)1 2010
Abstract
Abstract
A 49-year old patient with chronic kidney disease was referred for evaluation of living donor kidney transplantation from his spouse in a blood group incompatible setting. CLINICAL INVESTIGATIONS: Patient blood group was 0, donor blood group was A, subtype A. recipient isoagglutinin titer against do...
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PMID: 20013598
PDF is available here.
PDF is available here.
Transfusion (49)12 2009
Abstract
Transplantation (88)3 2009
Abstract
Three of the four patients with liver cirrhosis received rituximab over 3 weeks before LDLT, followed by PEs and post-LDLT IVIG, resulting in no rebound elevation of the isoagglutinin titers. The remaining patient, with fulminant hepatitis, received rituximab 3 days before the LDLT, resulting in ant...
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PMID: 19667930
PDF is available here.
PDF is available here.
Abstract
Although the patient number was small, the finding that there were no hemolytic reactions might promote emergency blood transfusion practices in Japan. High mortality rate and a low rate of uncross-matched, ABO-identical RCC transfusion in patients with compatible RCC transfusion suggest that promot...
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PMID: 19702231
PDF is available here.
PDF is available here.
Revista Medica de Chile (137)8 2009
Abstract
We report a 33 year-old female with a diagnosis of halothane-induce fulminant hepatic failure who was subjected to a liver transplant with an ABO-incompatible graft. The patient received a therapeutic protocol that included total plasma exchange, splenectomy and quadruple immunosuppression. After 5...
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PMID: 19915771
PDF is available here.
PDF is available here.
Transplantation (88)3 2009
Abstract
Abstract
We report two cases of AHR treated with plasmapheresis and rituximab in two ABO-compatible liver-transplant patients with preformed anti-human leukocyte antigen donor-specific antibodies. Patient 1 experienced a biopsy-proven AHR at day 10 post-transplant. She was treated by steroid pulses, and OKT3...
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PMID: 19610146
PDF is available here.
PDF is available here.
Transplantation (87)12 2009
Abstract
Our analysis aids in defining apheresis resource utilization and helps in risk stratification of incompatible renal transplantation. It also aids in predicting allograft rejection and provides an opportunity for preemptive monitoring and treatment....
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PMID: 19543070
PDF is available here.
PDF is available here.
Abstract
We experienced rapid and massive bleeding in a 57-year-old woman undergoing resection of ovarian tumor metastasis. One hour after the start of operation, blood loss increased due to adhesion of the tumor. The blood hemoglobin level decreased from 11.7 to 4.6 g x dl(-1). Since available matched homol...
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PMID: 19364007
PDF is available here.
PDF is available here.
Abstract
We infused a large amount of crystalloid, colloid, and 5% albumin. But he went into circulatory collapse before we could get type AB red blood cell (RBC) and hemoglobin was reduced to 3.8 g x dl(-1). We decided to transfuse 4 units of ABO incompatible type O RBC. Later, type AB RBC and other blood c...
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PMID: 19364015
PDF is available here.
PDF is available here.
Abstract
Transplantation (87)8 2009
Abstract
We present a retrospective review of our single-center experience with 60 consecutive ABOi kidney transplants and describe the evolution of our treatment protocol to one that consists only of a brief escalation in immunosuppression without long-term B-cell suppression from splenectomy or anti-CD20....
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PMID: 19384174
PDF is available here.
PDF is available here.
Abstract
The screening and titer detection of anti-D IgG in RhD negative pregnant women are valuable in the prediction and treatment of HDN....
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PMID: 19292952
PDF is available here.
PDF is available here.
Transplantation (87)6 2009
Abstract
DSA+TPA fell in the first 4 days after transplantation, and greater falls in DSA indicated absorption by the graft. This occurred for class I (57.8% fall compared with 20.2% for TPA, P<0.0005), HLA DR (63.0% vs. 24.3%, P<0.0004), and for HLA DP/DQ/DRB3-4 (34% vs. 17.5%, P=0.014). Peak DSA levels occ...
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PMID: 19300192
PDF is available here.
PDF is available here.
Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine / Zhongguo Zhong xi yi jie he xue hui, Zhongguo Zhong yi yan jiu yuan zhu ban (29)2 2009
Abstract
The antibody titer decreased after treatment in both groups to different extent; the effective rate was 90.0% in Group A and 56.7% in Group B. The bilirubin level in cord blood of Group A was lower than that in Group B significantly (P<0.01). No statistically significant difference was found between...
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PMID: 19382479
PDF is available here.
PDF is available here.
Vojnosanitetski pregled (66)2 2009
Abstract
The pre-transplant treatment consisting of 1-5 PE procedures and immunosuppressive therapy resulted in target ABO agglutinins titers below 4. During a 10-24 month follow-up three patients had an early acute rejection, one patient acute rejection and hemolytic anemia, two patients surgical complicati...
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PMID: 19281122
PDF is available here.
PDF is available here.
Hepato-gastroenterology (56)93 2009
Abstract
We report a case of adult A-to-O liver transplantation in which the recipient's preoperative IgG titer was 1:8192. Plasmapheresis, splenectomy, rituximab administration, and liver-directed anticoagulation therapy in addition to conventional immunosuppression effectively suppressed the antibody titer...
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PMID: 19760964
PDF is available here.
PDF is available here.
Abstract
DNA-based tests are increasingly being used to predict a blood group phenotype to improve transfusion medicine. This is possible because genes encoding 29 of the 30 blood group systems have been cloned and sequenced, and the molecular bases associated with most antigens have been determined. RBCs ca...
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PMID: 20008196
PDF is available here.
PDF is available here.
Abstract
We have recently described a beneficial effect of the combination of IVIG + rituximab on the reduction of anti-human leukocyte antigen (HLA) antibodies with subsequent improvement in rates of transplantation for highly HLA-sensitized patients as well as a potent anti-inflammatory effect that is bene...
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PMID: 19001810
PDF is available here.
PDF is available here.
Abstract
Abstract
We selected five JK*0 alleles that had been encountered by our reference laboratory in two or more samples from unrelated individuals and designed an allele-specific primer PCR assay for use as an initial screening tool. After in-house validation,we tested genomic DNA from a family: a mother and her...
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PMID: 20406024
PDF is available here.
PDF is available here.
Abstract
We have generated three novel anti-Ok(a) Mabs: MIMA-144 is an indirectly agglutinating IgG2b antibody, and MIMA-25 and MIMA-149 are directly agglutinating antibodies (IgM and IgA, respectively), underscoring their usefulness as typing reagents for the clinical laboratory....
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PMID: 20406026
PDF is available here.
PDF is available here.
Abstract
We advise integrating such a program into a national exchange program under supervision of an independent allocation authority. If no Good Samaritan donors are available, an unbalanced kidney paired-exchange program with compatible and incompatible pairs is another strategy that merits future develo...
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PMID: 20524290
PDF is available here.
PDF is available here.
Abstract
A total of 1,859 intestinal transplants was reported to UNOS during the past 20 years (1,822 deceased, and 37 living donors). Forty-three US transplant centers reported at least one intestinal transplant, among them, Jackson Memorial Hospital, Nebraska Medical Center and University of Pittsburgh Med...
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PMID: 20524278
PDF is available here.
PDF is available here.
Abstract
Abstract
Patients whose RBCs are D- may produce anti-D if they are exposed to D on donor RBCs. Except in emergency situations, patients whose RBCs lack D are transfused with only D- RBCs. Platelets carry no Rh antigens, but platelet units may be contaminated by RBCs that could carry D when these units are co...
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PMID: 19856725
PDF is available here.
PDF is available here.
Abstract
The development of RBC autoantibodies resulting from or associated with allogeneic blood transfusions is not an easily determined complication of RBC transfusions. This report discusses one patient who developed RBC autoantibodies in association with an allogeneic blood transfusion and alloimmunizat...
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PMID: 19856726
PDF is available here.
PDF is available here.
Abstract
Passenger lymphocyte syndrome (PLS) is a well-recognized complication that may follow a hematopoietic progenitor cell or solid-organ transplant. Typically, the syndrome presents as acute hemolysis of the recipient's RBCs, which have become serologically incompatible with blood group antibodies forme...
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PMID: 19856729
PDF is available here.
PDF is available here.
Nippon Jinzo Gakkai shi (51)1 2009
Abstract
Abstract
Bilirubin encephalopathy and kernicterus are preventable conditions. Nevertheless cases continue to occur. It is difficult to identify those infants who may develop severe hyperbilirubinemia, because icterus neonatorum occurs in most newborns. The aim of this guideline is to reduce the incidence of...
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PMID: 19785881
PDF is available here.
PDF is available here.
Transplantation (86)12 2008
Abstract
Ten matches moved forward to donation and transplantation, and one is pending. Eight of these matches involved NDD chains, two 2-way exchanges, and 1 a list exchange chain. These matches resulted in 27 transplants. Eighteen transplants occurred in NEPKE-only transplant centers, four in MAPEP-only ce...
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PMID: 19104415
PDF is available here.
PDF is available here.
Transplantation (86)12 2008
Abstract
Of the 276 registered pairs we created 183 computer-matched combinations. However, 62 of 183 recipients proved to have a positive crossmatch with their new donor, which was not predicted by the screening results of the recipient centers. Alternative solutions were found for 39 couples, resulting in...
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PMID: 19104416
PDF is available here.
PDF is available here.
Transplantation (86)12 2008
Abstract
Paired donation has been introduced successfully in the United Kingdom, adding to living donor transplant activity. The new national program has yielded fewer transplants than initially anticipated but as the scheme evolves, with the use of altruistic, nondirected donors to start a "chain" of transp...
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PMID: 19104403
PDF is available here.
PDF is available here.
Journal of Trauma (65)6 2008
Abstract
Of 25,599 trauma patients, 4,241 (16.6%) patients received 29,375 units of PRBC and 1,236 (29.1%) of the transfused patients received 5,166 units of URBC during their resuscitation. Patients requiring URBC had a higher mortality (39.6% vs. 11.9%, p < 0.001) and were more likely to require massive (>...
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PMID: 19077605
PDF is available here.
PDF is available here.
Abstract
We sought to maximize graft-versus-tumor while minimizing GVHD using tumor-specific allogeneic effector T cells rather than open-repertoire T cells. We transferred allogeneic CD8(+) pmel-1 or CD4(+) TRP-1 T cells specific for the melanoma-associated antigens, glycoprotein 100 (gp100) and tyrosinase-...
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PMID: 18799724
PDF is available here.
PDF is available here.
Clinical Chemistry (54)12 2008
Abstract
Transplantation Proceedings (40)10 2008
Abstract
Postoperative anti-donor blood-type antibody titer and B-cell level were effectively suppressed by early rituximab prophylaxis in all patients. HAI therapy was effective to prevent AMR and even resolved mild AMR. However, all patients suffered bacterial infections, and 1 died of septicemia with good...
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PMID: 19100487
PDF is available here.
PDF is available here.
Abstract
ABO incompatible transfusions are still a frequent cause of serious adverse transfusion reactions. Bedside check is intended to detect patient errors and prevent ABO mismatch. France is one of the few countries that includes ABO agglutination test for red blood cells in bedside checks. Evaluation of...
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PMID: 18930425
PDF is available here.
PDF is available here.
Abstract
We were able to list the most serious cases. Public and private hospitals have to notify the serious events and will be bound to evaluate professional practices. These acts will be taken into account by the regional-medical contract....
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PMID: 18938098
PDF is available here.
PDF is available here.