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Welcome to the Pubget Medical Subject Headings (MESH) browser. Click on a topic or subtopic below to explore related papers. In the gold box is the most recent paper about the current MESH term, and below are 20 related papers.
Hypersensitivity (7):
Recent article
Hypersensitivity
Abstract
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New England Journal of Medicine (365)14 2011
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Allergy is an immunological disorder of the upper airways, lung, skin, and the gut with a growing prevalence over the last decades in Western countries. Atopy, the genetic predisposition for allergy, is strongly dependent on familial inheritance and environmental factors. These obser...
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PMID: 21410266
PDF is available here.
PDF is available here.
Abstract
Inflammation is a disease of vigorous uncontrolled activated immune responses. Overwhelming reports have suggested that the modulation of immune responses by curcumin plays a dominant role in the treatment of inflammation and metabolic diseases. Observations from both in-vitro and in...
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PMID: 20828642
PDF is available here.
PDF is available here.
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We compared children living on farms with those in a reference group with respect to the prevalence of asthma and atopy and to the diversity of microbial exposure. In one study--PARSIFAL (Prevention of Allergy-Risk Factors for Sensitization in Children Related to Farming and Anthroposophic Lifestyle...
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PMID: 21345099
PDF is available here.
PDF is available here.
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We propose and validate a strategy to identify genes in which changes in dosage alter susceptibility to disease-relevant phenotypes in the mouse. Our approach relies on sensitized phenotypic screening of megabase-sized chromosomal deletion and deficiency lines carrying altered copy numbers of ∼30...
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PMID: 21204268
PDF is available here.
PDF is available here.
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The hygiene hypothesis was proposed more than two decades ago, but its mechanism remains unclear. This review focuses on recent advances in the field, especially on the role played by dendritic cells (DCs) and their modulating effects on various infections and allergic diseases, incl...
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PMID: 21200379
PDF is available here.
PDF is available here.
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International Archives of Allergy and Immunology (155 Suppl 1) 2011
Eosinophils in allergy and related diseases. Proceedings of a Workshop. Tokyo, Japan. June 19, 2010.
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We reported that TRX directly modulated the chemotaxis of eosinophils, which have been shown to play a pivotal role in the mechanism of allergic airway inflammation, in the absence of T helper (Th)1 or Th2 cytokines. Further, serum TRX levels in patients with asthma were significantly increased in p...
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PMID: 21646810
PDF is available here.
PDF is available here.
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We recently reported that cockroach extracts contain pepstatin A-sensitive proteases that activate PAR-2 and induce activation and degranulation of human eosinophils. This review focuses on the effects of cockroach on various inflammatory cells, including eosinophils, epithelial cells, fibroblasts,...
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PMID: 21646809
PDF is available here.
PDF is available here.
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We will first review the physiological role of HO-1 as determined by the analysis of HO-1-deficient individuals. This will be followed by an examination of the effect of HO-1 within immunopathological contexts such as immune disorders (autoimmunity and allergy) or infections. A section will be devot...
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PMID: 20941616
PDF is available here.
PDF is available here.
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We investigated the mechanism of the anti-allergy effect of FU. FU extract (80 mg/kg), orally administered to Sprague-Dawley (SD) rats, significantly inhibited the passive cutaneous anaphylaxis (PCA) reaction. It inhibited the compound 48/80-induced release of histamine from rat peritoneal mast cell...
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PMID: 21821956
PDF is available here.
PDF is available here.
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Ugeskrift for laeger (172)50 2010
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A 22 year-old patient wearing a down- and feather jacket was brought to the emergency department after a car accident. Initial treatment was according to Advanced Trauma Life Support principles. The patient was awake and stable. A computed tomography showed no abnormalities. However, a severe asthma...
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PMID: 21156114
PDF is available here.
PDF is available here.
The practising midwife (13)11 2010
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We will see new CRTH2 antagonists reaching the market for the treatment of asthma, rhinitis, atopic dermatitis and/or COPD seems good....
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PMID: 20946089
PDF is available here.
PDF is available here.
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The indication for Helicobacter pylori (H. pylori) eradication has been extended to few extragastroduodenal diseases. Scientific rigor needs to be applied as the list of clinical manifestations potentially related to H. pylori has disproportionally grown to its scientific evidence. Some potential be...
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PMID: 20827182
PDF is available here.
PDF is available here.
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We will be able to understand the heterogeneity observed in natural history, response to treatments, susceptibility to infections, genetic risk factors, and associations with other atopic disorders....
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PMID: 20944637
PDF is available here.
PDF is available here.
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Medical Laboratory Observer (42)10 2010
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Around 300 million people world-wide suffer from asthma, and the prevalence of allergic diseases has increased. Much effort has been used in the study of mechanisms involved in the immune response observed in asthma to intervene for the treatment of this condition. During inflammation in asthma, Th2...
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PMID: 20412136
PDF is available here.
PDF is available here.
Journal of Immunology (185)7 2010
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We have previously shown that group V secretory phospholipase A(2) (sPLA(2)) regulates phagocytosis of zymosan and Candida albicans by a mechanism that depends on fusion of phagosomes with late endosomes in macrophages. In this study, we report that group V sPLA(2) (Pla2g5)-null mice exposed to an e...
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PMID: 20817863
PDF is available here.
PDF is available here.
Arerugi = [Allergy] (59)9-10 2010
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Regulatory Peptides (164)2-3 2010
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We analyzed the availability of VIP and its protease, neutral peptidase (NEP), in naïve and Aspergillus-sensitized and challenged murine lungs after 3, 7, and 14days. Both VIP and NEP were predominantly localized to the columnar epithelia of the airways in naïve lungs. A marked decrease in VIP occ...
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PMID: 20566347
PDF is available here.
PDF is available here.
Kidney International (78)10 2010
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Although chemokines, as chemotactic factors, were already known in 70's of the past century, it was only the progress in molecular biology, genetics and immunology which occurred in the past few years that opened the way to discover new molecules, their chemical structure and biological functions. F...
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PMID: 19388544
PDF is available here.
PDF is available here.
Abstract
Component resolved diagnostics introduces new possibilities regarding diagnosis of allergic diseases and individualized, allergen-specific treatment. Furthermore, refinement of IgE-based testing may help elucidate the correlation or lack of correlation between allergenic sensitization and allergic d...
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PMID: 20628838
PDF is available here.
PDF is available here.
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Histamine plays a key role in physiological processes through its interaction with H(1-4) histamine receptors. The H(1) receptor is a key element in the pathophysiology of allergic responses. H(1) antihistamine use is a key strategy for therapy in allergy.
Several new chemical entities with improved...
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PMID: 20716024
PDF is available here.
PDF is available here.
The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology (21)3 2010
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We evaluated anti-allergic effects of a Dahi (yogurt) containing probiotic Lactobacillus acidophilus, L. casei and normal Dahi culture Lactococcus lactis biovar diacetylactis (named probiotic Dahi) on ovalbumin induced allergy in mice.
Allergy was induced by injecting (i.p.) ovalbumin at 0 and 14 da...
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PMID: 20931427
PDF is available here.
PDF is available here.
Internal Medicine Journal (40 Suppl 4) 2010
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The prevalence of sensitization to cat and dog allergens is high in the general population and poses a challenge to the physician managing allergic asthma. Adequate allergen avoidance is difficult to achieve because of the physical characteristics of airborne animal allergens and patient noncomplian...
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PMID: 20929605
PDF is available here.
PDF is available here.
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There is evidence that allergy to common indoor pets, particularly cats and dogs, is closely associated with symptomatic asthma in the United States. Because the presence of pets in a home is a potentially modifiable factor, it is important to consider how much asthma morbidity and health care cost...
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PMID: 20929604
PDF is available here.
PDF is available here.
Abstract
Some environmental toxins like DDT and other chlorinated compounds accumulate in the body because of their fat-soluble nature. Other compounds do not stay long in the body, but still cause toxic effects during the time they are present. For serious health problems to arise, exposure to these rapidly...
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PMID: 21155623
PDF is available here.
PDF is available here.
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The criteria used to identify persons with asthma in epidemiologic studies are varying and, depending on the method used, can be challenging and resource consuming.
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PMID: 20800786
PDF is available here.
PDF is available here.
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Pseudotumor-like reactions can be caused by high wear, but may also occur around implants with low wear, likely because of a metal hypersensitivity reaction. Histologic features including synovial integrity, inflammatory cell infiltrates, tissue organization, and metal particles may help differentia...
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PMID: 20458645
PDF is available here.
PDF is available here.
Orthopedics (33)9 2010
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Early causes of hip pain within the first year of total hip replacement (THR) include failure of fixation, infection, instability, other sources of pain (eg, lumbar spine), and mechanical dysfunction such as psoas tendon impingement or other soft tissue irritation. Metal-on-metal THRs may present wi...
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PMID: 20839693
PDF is available here.
PDF is available here.
Orthopedics (33)9 2010
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In this single-surgeon series, both resurfaced hips in 1 woman and a total hip arthroplasty in another were revised for symptomatic pseudotumor (3 of 588 hips; 0.51% overall incidence; 2.2% in women). All 3 hips had 50-mm acetabular components. There was no difference in mean lateral opening angle (...
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PMID: 20839676
PDF is available here.
PDF is available here.
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While the prevalence of and risk factors for asthma in childhood have been studied extensively, the data for late adolescence are more sparse. The aim of this study was to provide up-to-date information on the prevalence of and risk factors for asthma in the transitional period between childhood and...
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PMID: 20408968
PDF is available here.
PDF is available here.
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Events and exposures in pregnancy can have critical effects on fetal development with lasting implications for subsequent health and disease susceptibility. There is growing interest in how modern environmental changes influence fetal immune development and contribute to the recent epidemic of aller...
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PMID: 20587128
PDF is available here.
PDF is available here.
Vox Sanguinis (99)2 2010
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IgA deficiency is common (1/500) and up to 40% of affected individuals will develop anti-IgA. A few studies suggested that passive transfusion of anti-IgA was not associated with an increased risk of allergic reactions. This study was designed to assess the safety of transfusing blood components con...
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PMID: 20345516
PDF is available here.
PDF is available here.
Abstract
We sought to evaluate the association between early-life pet exposure and allergic sensitization at age 18 years.
Teenagers who had been enrolled in the Detroit Childhood Allergy Study birth cohort in 1987-1989 were contacted at age 18 years. Serum total and allergen-specific IgE levels to 7 common...
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PMID: 20579718
PDF is available here.
PDF is available here.
Abstract
We reveal in this study the IgE production-suppressing activity of the PP fraction in bovine milk. The PP fraction suppressed IgE production by human myeloma cell line U266 cells by depressing the IgE mRNA expression. The suppressive activity of the PP fraction was facilitated by trypsin digestion....
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PMID: 20622462
PDF is available here.
PDF is available here.
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The identification of chemokines in blood platelets has strengthened our view of these cells as participants in immune host defense. Platelet chemokines representing prestored and rapidly releasable proteins may play a major role as first-line inflammatory mediators. This is evident from their capab...
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PMID: 20213276
PDF is available here.
PDF is available here.
Mucosal Immunology (3)4 2010
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We highlight the factors that are specific for this period of life and discuss how they could have an impact on oral tolerance. We pay particular attention to maternal influence on early oral tolerance induction through breast-feeding and outline the major parameters that could be modified to optimi...
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PMID: 20485330
PDF is available here.
PDF is available here.
Mucosal Immunology (3)4 2010
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The absolute requirement of the pulmonary immune system is to limit the inflammatory consequences of inhaled infectious agents while maintaining tolerance to harmless aeroallergens. This tolerance is maintained by a complex network of cells and molecules interacting with lung stromal...
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PMID: 20505664
PDF is available here.
PDF is available here.
Eastern Mediterranean health journal = La revue de sante de la Mediterranee orientale = al-Majallah al-sihhiyah li-sharq al-mutawassit (16)7 2010
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The International Study of Asthma and Allergies in Childhood (ISAAC) uses standardized symptom-based questionnaires to describe the prevalence of symptoms of asthma, rhinoconjunctivitis and eczema in children worldwide. Three governorates in the Syrian Arab Republic (Aleppo, Lattakia and Tartous) pa...
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PMID: 20799526
PDF is available here.
PDF is available here.
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The aim of this study was to evaluate the impact of urban air pollution, assessed through reliable indicators of exposure, on asthma and allergies in schoolchildren. A validated dispersion model combining data on traffic conditions, topography, meteorology and background pollution wa...
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PMID: 20075054
PDF is available here.
PDF is available here.
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We report that the probiotic Escherichia coli Nissle 1917 strain (EcN) is able to activate DC, as shown by important cytokine synthesis together with up-regulation of membrane expression of CD40, CD80 and CD86. This EcN-induced DC activation was strictly dependent on the TLR4 signaling pathway and w...
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PMID: 20432233
PDF is available here.
PDF is available here.
Abstract