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Immunoproliferative Disorders (3):
Recent article
Immunoproliferative Disorders
Annals of Hematology (85)1 2006
Abstract
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Abstract
These data in the CSQ model of cardiac dysfunction indicate that membrane-targeted PI3K activity plays a detrimental role in heart failure, and its inhibition represents a novel therapeutic approach to ameliorate cardiac dysfunction and improve survival....
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PMID: 15936620
PDF is available here.
PDF is available here.
Abstract
The term AIL/AL refers to a heterogeneous group of conditions not unique to a particular type of lymphoid cell. These lesions are easily recognised by the histopathologist because of their extremely unusual angiocentric pattern. Although rare, AIL/AL may present as nodal lesions in children ab initi...
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PMID: 15858132
PDF is available here.
PDF is available here.
Transplant International (17)2 2004
Abstract
During immunosuppressive medication, Epstein-Barr virus (EBV) infection is associated with a risk of developing posttransplant lymphoproliferative disease (PTLD). The appropriateness of a spontaneous EBV B-cell transformation (SET) assay as a monitor of EBV-specific immunity was evaluated to investi...
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PMID: 14652716
PDF is available here.
PDF is available here.
Abstract
For a considerable time, hyperviscosity syndrome has been widely recognized as a serious manifestation of polycythemia and plasma cell dyscrasia. In this article a number of conditions will be considered in which the association with hyperviscosity has been more recently recognized and is less widel...
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PMID: 14631545
PDF is available here.
PDF is available here.
Journal of the Neurological Sciences (213)1-2 2003
Abstract
We report a rare case involving initial progression of CNS symptoms followed by a pulmonary abnormality.A 14-year-old girl suffered from high fever, ataxic gait and paraparesis. MRI revealed diffuse T2 high signals with multiple gadolinium enhancements in the cerebellum, brain stem and cerebral whit...
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PMID: 12873757
PDF is available here.
PDF is available here.
Journal of Endocrinological Investigation (26)8 Suppl 2003
Abstract
Abstract
We treated a 57-year-old woman with AIL of the lung in whom chest radiography and computed tomography showed ground-glass opacity in the left lower lobe and lingular segment. Since macroscopical and intraoperative lung biopsy findings could not rule out the possibility of malignancy, including malig...
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PMID: 12229222
PDF is available here.
PDF is available here.
Abstract
We recommend the imaging of kidneys for diagnosis and following renal biopsy to evaluate the renal involvement of angiocentric immunoproliferative lesions.
Copyright 2002 by the National Kidney Foundation, Inc....
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PMID: 11877592
PDF is available here.
PDF is available here.
Abstract
We review the literature on this unusual entity and discuss the clinical and pathologic findings....
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PMID: 11210903
PDF is available here.
PDF is available here.
Abstract
Leukemia & Lymphoma (39)1-2 2000
Abstract
I PCR in 1 pro-B-ALL, 1 c-ALL, and 2 MM. CDR III IgH PCR has been confirmed as an efficient method for determining clonality in B-cell neoplasias. Some additional monoclonal products can be seen with CDR I-based PCR. Detection of monoclonality depends on the maturation grade of the neoplastic B-cell...
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PMID: 10975394
PDF is available here.
PDF is available here.
Bulletin du cancer (84)8 1997
Abstract
The occurrence of cancers in patients with primary humoral immunodeficiency syndrome (X-linked agammaglobulinemia, common variable immunodeficiency, IgA deficiency) is more than mere coincidence. An increased risk of non Hodgkin's lymphoma and gastric adenocarcinoma, particularly for patients with c...
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PMID: 9339187
PDF is available here.
PDF is available here.
Abstract
The acturial probability of malignant transformation was analyzed in a series of 263 patients with monoclonal gammopathy of undetermined significance (MGUS) over a 15-year period and followed from 5 to 20 years. At a median follow-up of 11.5 years, 157 patients (59.7%) had died of causes unrelated t...
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PMID: 9161471
PDF is available here.
PDF is available here.
Abstract
Three distinct monoclonal gammopathies were identified in the serum of a 79 year-old man. In 1972 he presented with Waldenström's macroglobulinemia IgM Kappa. Twenty years later multiple myeloma was diagnoses. Serum protein electrophoresis performed at this time showed three monoclonal bands. Immun...
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PMID: 9247046
PDF is available here.
PDF is available here.
Abstract
We suggest that this is the first such case in the literature. CONCLUSION: Patients with the Dubowitz syndrome will Dubowitz syndrome will require long-term follow up because there is a considerable risk for the syndrome to co-exist with primary immunodeficiency or for malignancies to develop....
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PMID: 8741037
PDF is available here.
PDF is available here.
Orvosi Hetilap (137)9 1996
Abstract
Angiocentric T-cell lymphoma of the lung. The case history of a patient with primary angiocentric T-cell lymphoma of the lung having an unusually long survival period (> 10 years) is presented. Attention is paid to the possibilities of differential diagnosis that should be taken into account in the...
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PMID: 8714041
PDF is available here.
PDF is available here.
Abstract
Bone Marrow Transplantation (17 Suppl 2) 1996
Abstract
Bone Marrow Transplantation (17 Suppl 2) 1996
Abstract
Abstract
We studied 20,354 patients in the Swedish Cancer Register during 1958-88. A second primary cancer was reported in 1605 patients, compared with an expected number of 1109.5 [standardised incidence ratio (SIR) = 1.45, 95% confidence interval (CI) = 1.38-1.52]. The highest risk was found among patients...
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PMID: 8546916
PDF is available here.
PDF is available here.
Abstract
Abstract
Abstract
Abstract
The ultrasonographic findings in a one-and-a-half-year-old female basenji with immunoproliferative enteropathy are described. On ultrasonographic examination, generalised thickening of the small bowel wall was found, ranging between 4 and 6 mm. The normal layered appearance of the intestinal wall wa...
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PMID: 7723294
PDF is available here.
PDF is available here.
Haematologica (80)1 1995
Abstract
I MM treated with alpha-IFN (3 MU 3 times a week for at least 6 months) were compared to 129 untreated similar patients. Four patients in the IFN group showed a monoclonal component reduction > 50% versus none in the control group, and 25% of patients suffered disease progression (MC increase > 50%...
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PMID: 7758989
PDF is available here.
PDF is available here.
Mayo Clinic Proceedings (69)7 1994
Abstract
On the basis of mouse plasmacytoma models, increased expression of c-myc in B lymphocytes may be the initial oncogenic event that leads to MGUS in humans. Over time, this monoclonal subpopulation may acquire additional genetic abnormalities, such as aberrant interleukin (IL) 1 beta expression. Becau...
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PMID: 8015336
PDF is available here.
PDF is available here.
Zentralblatt fur Pathologie (140)2 1994
Abstract
We describe a case of a 48 year old man who presented repeatedly with a neck lymph node tumor. The tumor grew insidiously over 11 years and the patient died at the age of 58 with the generalization of the tumor into the right cervical, paratracheal lymph nodes and spleen. The tumor was composed of s...
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PMID: 7947623
PDF is available here.
PDF is available here.
Abstract
We report a pulmonary angiocentric immunoproliferative lesion (AIL) in an 11-year-old boy with chronic active Epstein-Barr virus (EBV) infection. The phenotypes of the proliferating lymphoid cells in the biopsied pulmonary lesion were CD2+, CD3+, CD4+, CD5+, CD7+, and HLA-DR+. EBV DNA was detected i...
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PMID: 8179077
PDF is available here.
PDF is available here.
Abstract
Abstract
Abstract
Abstract
Human Pathology (22)11 1991
Abstract
We assessed the clonality of eight AILs using restriction fragment analysis, the Southern blot technique, and probes to assess the configuration of the T-cell receptor beta, gamma, and delta chain genes and the immunoglobulin heavy and K light chain genes. In addition, the presence of the Epstein-Ba...
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PMID: 1743700
PDF is available here.
PDF is available here.
Histopathology (19)1 1991
Abstract
Immunitat und Infektion (19)3 1991
Abstract
We briefly outline 6 syndromes, two of which--the "pluripotential chronic immunoproliferative syndrome" (CPIS) and the "angioimmunoblastic lymphadenopathy" (AILD)--are discussed in more detail. We favor the notion that CPIS is a variant form of AILD clinically dominated by severe autoimmune hemolyti...
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PMID: 1916867
PDF is available here.
PDF is available here.
Abstract
Seminars in Hematology (28)1 1991
Abstract
La Revue du praticien (41)1 1991
Abstract
Pathology annual (26 Pt 2) 1991
Abstract
This report has attempted to review the pathology of immunoblastic proliferations, to indicate their similarities and differences, and hopefully to offer some guidelines in the approach to their diagnosis. Their pathology, immunology, and clinical features overlap, making it necessary to evaluate al...
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PMID: 1861884
PDF is available here.
PDF is available here.
Abstract
We report here a rare case of angiocentric immunoproliferative lesion (AIL) of the stomach. The patient was a 61-year-old Japanese female whose medical history was unremarkable. Following a complaint of abdominal discomfort, a submucosal tumour of the stomach was found and gastrectomy was done. Hist...
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PMID: 1900973
PDF is available here.
PDF is available here.
Human Pathology (21)10 1990
Abstract
We could not confirm identity of PR with other angiocentric immunoproliferative lesions....
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PMID: 2210727
PDF is available here.
PDF is available here.
Pathologie Biologie (38)8 1990
Abstract
Abstract
We used oligonucleotide primers designed from DNA sequences unique to the long internal direct repeated region of Epstein-Barr virus (EBV) to enzymatically amplify this segment of the EBV genome in formalin-fixed, paraffin-embedded tissues. The products amplified from EBV templates were detected by...
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PMID: 2163603
PDF is available here.
PDF is available here.
Annals of Internal Medicine (112)6 1990
Abstract
Monoclonal immunoglobulin deposition occurs in tissues as Congo Red binding fibrils in light chain amyloidosis, as less structured deposits in light chain deposition disease, and as similar but distinct deposits in light and heavy chain deposition disease. The nonamyloid forms were found in 13 patie...
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PMID: 2106817
PDF is available here.
PDF is available here.
Abstract
We have determined the sequences of heavy (VH) and light (VL) chain variable region genes for several human monoclonal autoantibodies and compared these with corresponding sequences reported for other antibodies and autoantibodies. Our data reveal that natural autoantibodies can be encoded by nonmut...
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PMID: 2130121
PDF is available here.
PDF is available here.
Abstract
Cellular Immunology (125)1 1990
Abstract
We tested whether C3H/gld-IgG supports the growth of the IL-3-dependent cell line, FDC-P2/185-4. Serum IgG from C3H/gld mice stimulated FDC-P2/185-4 cells to proliferate. On the other hand, IgG from C3H/HeJ-+/+ did not show such activity. This activity increased with age in both sexes of C3H/gld mic...
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PMID: 2293897
PDF is available here.
PDF is available here.
Abstract
Abstract
The clinical significance of Bence Jones (BJ) proteinuria at low concentration (less than 0.2 g/24 hours) was investigated in 33 unselected patients who had no intact monoclonal immunoglobulin in their serum. The great majority (79%) of the patients were recognized as having malignant lymphoprolifer...
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PMID: 2929504
PDF is available here.
PDF is available here.
La Tunisie medicale (67)4 1989
Abstract
Abstract
The neuropathologic findings of brains and spinal cords removed at autopsy from 26 infants and children with AIDS is described; in two cases, only the spinal cords were available. The most common finding in the brains was dystrophic calcification of blood vessels of all calibers in the basal ganglia...
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PMID: 2736140
PDF is available here.
PDF is available here.
Abstract
We report the diagnostic surgical pathology of two children who underwent multivisceral abdominal transplantation and survived for 1 month and 6 months. There is little relevant literature, and diagnostic criteria for the various clinical possibilities are not established; this is made more complica...
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PMID: 2557597
PDF is available here.
PDF is available here.
Abstract
Sixty-six consecutive patients exhibiting isolated urinary excretion of monoclonal free light chains, i.e. Bence Jones protein (BJP), on screening investigation for serum and urine monoclonal immunoglobulins were studied in order to better define the spectrum of immunoproliferative disorders associa...
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PMID: 3179959
PDF is available here.
PDF is available here.
Abstract
This report describes the clinical and pathologic features of four patients with a florid, systemic immunoblastic proliferation. The blood of these patients exhibited a mild to marked leukocytosis with a high percentage of immunoblasts and plasma cells. The bone marrow also was infiltrated extensive...
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PMID: 3278799
PDF is available here.
PDF is available here.
Abstract
This article discusses the ontogeny of human T cells along with the relationship of normal T-cell maturation to the development of various malignant T-cell syndromes. The impact of monoclonal antibody technology, the discovery of the T-cell receptor for antigen, and the discovery of mechanisms of th...
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PMID: 3282755
PDF is available here.
PDF is available here.
Abstract
These results provide evidence that legionellosis is an important pneumonia etiology in patients with malignant hematological diseases. Thus, Legionella diagnostics should be applied routinely, and antibiotics effective in the treatment of legionellosis should be added to the usual therapy in patien...
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PMID: 3337917
PDF is available here.
PDF is available here.
Abstract
Seventy-five cases of lymphoreticular lesions of the gastrointestinal tract were studied by the immunoperoxidase method on paraffin sections which demonstrated cytoplasmic markers, in particular immunoglobulin (Ig) in B-lymphocytes and alpha-1-antichymotrypsin in histiocytes. There were 4 cases of b...
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PMID: 3329410
PDF is available here.
PDF is available here.
Human Pathology (18)10 1987
Virus-associated hemophagocytic syndrome: identification of an immunoproliferative precursor lesion.
Abstract
We describe the case of a patient with Epstein-Barr virus-associated VAHS in which initial lymph node biopsy samples showed an immunoproliferative lesion that preceded the usual generalized histiocytic proliferation. This finding suggests that some cases of VAHS may have an immunoproliferative precu...
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PMID: 2820860
PDF is available here.
PDF is available here.
Disease Markers (5)3 1987
Abstract