Abstract
Our results confirm the importance of pH and related geochemical factors in fine-tuning acidophilic microbial community structure and function at the species and strain level, and demonstrate the broad utility of proteomics in laboratory community studies....
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PMID: 21228889
PDF is available here.
Abstract
All treated dentin sections showed occluded dentin tubules; with the group A3 showing the highest percent of occluded dentin tubules. The precipitates in the dentin tubules treated with A3 remained while those treated with OX/Ca or OX/P dissolved after exposure to an acidic buffer....
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PMID: 21874938
PDF is available here.
Abstract
Hexokinases are conserved proteins functioning in glucose sensing and signaling. The rice blast fungus Magnaporthe oryzae contains several hexokinases, including MoHxk1 (hexokinase) and MoGlk1 (glucokinase) encoded respectively by MoHXK1 and MoGLK1 genes. The heterologous expression of MoGlk1 and MoH...
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PMID: 21818394
PDF is available here.
Abstract
Single wall Carbon Nanotubes (SWCNTs) are hydrophobic and do not disperse in aqueous solvents. Acid functionalization of SWCNTs results in attachment of carboxy and sulfonate groups to carbon atoms and the resulting acid functionalized product (AF-SWCNTs) is negatively charged and disperses easily in...
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PMID: 21818289
PDF is available here.
Abstract
To compare the ability of two new desensitizing toothpaste technologies (one a 5% NovaMin-based toothpaste and the other an 8% arginine-based toothpaste) to occlude patent dentin tubules in a clinical environment relative to a negative control of water and a control toothpaste after four days of twic...
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PMID: 21905402
PDF is available here.
Abstract
To determine the effect of low-concentration daily topical fluoride application on fluoride release of Giomer and Compomer and to compare the amount of fluoride release from Giomer to that of Compomer.
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PMID: 21521917
PDF is available here.
Abstract
A laboratory-scale, four-stage continuous-flow reactor system was constructed to test the viability of high-strength acid mine drainage (AMD) and municipal wastewater (MWW) passive co-treatment. Synthetic AMD of pH 2.6 and acidity of 1870 mg L(-1) as CaCO3 equivalent containing a mean 46, 0.25, 2.0,...
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PMID: 21488509
PDF is available here.
Abstract
Consuming a highly acidic diet can lead to erosion or excessive wear of dental hard tissues, resulting in the need for oral rehabilitation. Previously, a severely eroded dentition could be rehabilitated only by extensive crown and bridge placement or by removable partial dentures. Ho...
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PMID: 21613039
PDF is available here.
Abstract
As previous work proposed commercial expectations for soluble bio-organic substances (SBO) isolated from compost of urban food, gardening and park trimming residues as chemical auxiliaries, nine urban bio-wastes (BW) treated by aerobic and anaerobic digestion for 0-360 days were used to extract SBO...
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PMID: 20888748
PDF is available here.
Abstract
BINOL-derived phosphoric acids have emerged during the last five years as powerful chiral Brønsted acid catalysts in many enantioselective processes. The most successful transformations carried out with chiral BINOL phosphates include C-C bond formation reactions. The recent advances have been revi...
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PMID: 20820680
PDF is available here.
Marion Tarbe,
Itxaso Azcune,
Eva Balentová,
John J Miles,
Emily E Edwards,
Kim M Miles,
Priscilla Do,
Brian M Baker,
Andrew K Sewell,
Jesus M Aizpurua,
Céline Douat-Casassus and
Stéphane Quideau
Abstract
β-Lactam peptides were envisioned as conformational constraints in antigenic peptides (APs). Three different β-lactam tripeptides of varying flexibility were prepared in solution and incorporated in place of the central part of the altered melanoma associated antigenic peptide Leu(27)-Melan-A(26-3...
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PMID: 20927455
PDF is available here.
Abstract
The asymmetric Friedel-Crafts alkylation reaction of indoles with α,β-unsaturated ketones catalyzed by chiral phosphoric acid is reported. A wide range of indoles and 4,7-dihydroindoles were allowed to react with α,β-unsaturated ketones to give the corresponding 1,4-adducts in good to high chemi...
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PMID: 20877865
PDF is available here.
Abstract
We have analyzed the role of the platinum complexes in the observed reactions and studied the progress of the detected transformations upon variation of the reaction conditions....
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PMID: 20922260
PDF is available here.
Abstract
The emergence of antibiotic-resistant Helicobacter pylori strains has necessitated a search for alternative therapies for the treatment of this infection. The aim of this study was to evaluate whether or not polysaccharide fractions from Aloe vera are effective in inhibiting the adherence of H. pylor...
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PMID: 21054402
PDF is available here.
Abstract
The prevention of aggregation in therapeutic antibodies is of great importance to the biopharmaceutical industry. In our investigation, acid-induced aggregation of monoclonal IgG1 and IgG2 antibodies was studied at pH 3.5 as a function of salt concentration and buffer type. The extent of aggregation...
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PMID: 20843079
PDF is available here.
Abstract
We identified Rab GTPase 14, which regulates apoptotic cell degradation in Caenorhabditis elegans. rab-14 mutants accumulate many persistent cell corpses owing to defective cell corpse clearance. Loss of rab-14 function affects several steps of phagosome maturation including phagosomal acidification...
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PMID: 20921409
PDF is available here.
Abstract
Weak acids are widely used as food preservatives (e.g., acetic, propionic, benzoic, and sorbic acids), herbicides (e.g., 2,4-dichlorophenoxyacetic acid), and as antimalarial (e.g., artesunic and artemisinic acids), anticancer (e.g., artesunic acid), and immunosuppressive (e.g., mycop...
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PMID: 20955006
PDF is available here.
Abstract
I = 0.5 (NaClO(4)). The failure to detect significant catalysis by general acids of chlorine transfer from 1 to the nucleophile, together with the observed inverse solvent deuterium isotope effect on the hydronium ion-catalysed reaction (k(H)/k(D) = 0.37), indicates that this process occurs by proto...
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PMID: 20664852
PDF is available here.
Abstract
Staphylococcus aureus is an important food poisoning bacterium. In food preservation, acidification is a well-known method. Permeant weak organic acids, like lactic and acetic acids, are known to be more effective against bacteria than inorganic strong acids (e.g., HCl). Growth experiments and metab...
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PMID: 20921988
PDF is available here.
Abstract
A fermented soybean paste known as doenjang is a traditional fermented food that is widely consumed in Korea. The quality of doenjang varies considerably by its basic ingredients, species of microflora, and fermentation process. The classification of predefined metabolites (e.g. amino acids, organic...
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PMID: 20572059
PDF is available here.
Abstract
In its broadest definition, biomass can be described as all material that was or is a part of a living organism. For renewable energy applications, however, the definition of biomass is usually limited to include only materials that are plant-derived such as agricultural residues (e.g., wheat straw,...
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PMID: 19768622
PDF is available here.
Abstract
Platinum compounds, including cis-dichlorodiaminoplatinum(II) or cisplatin, are an important class of anti-cancer drugs, which should be carefully monitored in the biological fluids. In this study, electrodeposition coupled with electrothermal atomic absorption spectrometry (ETAAS) was used for dete...
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PMID: 20382490
PDF is available here.
Abstract
Factorial designs were employed to analyze the inhibitory effects of acetic, butyric, lactic, and propionic acids on composting microorganisms. Compost samples were withdrawn on different days of composting and treated with acids alone and in combination (at 0 and 0.5 mmol/g). Microorganisms were en...
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PMID: 20363618
PDF is available here.
Abstract
To reduce the recalcitrance and enhance enzymatic activity, dilute H(2)SO(4) pretreatment was carried out on Alamo switchgrass (Panicum virgatum). Ball-milled lignin was isolated from switchgrass before and after pretreatment. Its structure was characterized by (13)C, HSQC, and (31)P NMR spectroscop...
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PMID: 19701727
PDF is available here.
Abstract
We have already identified the gene encoding 4THase (Af-tth) in this bacterium. The heterologous expression of Af-tth in Escherichia coli resulted in the formation of inclusion bodies of the protein in an inactive form. The recombinant protein (Af-Tth) was successfully activated after an in vitro re...
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PMID: 20546308
PDF is available here.
Abstract
The presence of pharmaceuticals in the environment is a very important problem that requires analytical solutions. The wide variety of matrices and, usually, the low pharmaceuticals levels in the environmental samples requires high sensitive and selective analytical procedures. Wastewaters are one o...
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PMID: 20602981
PDF is available here.
Abstract
We use a combination of laboratory and field-based experiments to show that levels of dissolved CO(2) predicted to occur in the ocean this century alter the behavior of larval fish and dramatically decrease their survival during recruitment to adult populations. Altered behavior of larvae was detect...
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PMID: 20615968
PDF is available here.
Abstract
We investigated the condensed-phase reactions of biogenic VOCs with C double bond C bonds (limonene, C(10)H(16), and terpineol, C(10)H(18)O) catalyzed by sulfuric acid by both bulk solution (BS) experiments and gas-particle (GP) experiments using a flow cell reactor. Product analysis by gas chromato...
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PMID: 20550185
PDF is available here.
Abstract
We investigate whether intrinsic defects in ice surface segregate. We predict that hydronium, hydroxide, and the Bjerrum L- and D-defects are all more stable at the surface. However, the energetic cost to create a D-defect at the surface and migrate it into the bulk crystal is smaller than its bulk...
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PMID: 20615938
PDF is available here.
Abstract
We determined whether growth in differing NaCl concentrations alters the susceptibility of V. parahaemolyticus O3:K6 to other environmental stresses. Vibrio parahaemolyticus was grown at a 1% or 3% NaCl concentration, and the growth and survival of the organism were examined under acid or temperatur...
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PMID: 20472729
PDF is available here.
Abstract
We combined DsrAB gene sequencing and sulfur isotopic profiling to identify the phylogeny and distribution of SRB and to assess their metabolic activity in salt marsh sediments exposed to acid mine drainage (AMD) for over 100 years. Recovered dsrAB sequences from three sites sampled along an AMD flo...
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PMID: 20472728
PDF is available here.
Abstract
In an experiment delineating aciduric strains, food and clinical Listeria monocytogenes isolates tended to produce the most biomass whereas ovine and avian strains produced comparatively less biomass when exposed to high levels of sodium diacetate (SD) and potassium sorbate. Compared...
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PMID: 20511423
PDF is available here.
Abstract
The formation of cis-anethole and various dimers as a result of the exposure of trans-anethole to microporous solid acids (dealuminated HY zeolites), or UV-Vis irradiation was established by means of high resolution gas chromatography coupled to mass spectrometry. 3,4-bis-(4-Methoxyphenyl)-(E)-hex-2...
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PMID: 20657405
PDF is available here.
Abstract
Using a reference-condition comparison, recovery of benthic invertebrate communities from acidification was assessed in three lakes in Killarney Wilderness Park approximately 40-60 km from the massive metal smelters in Sudbury, Canada. Test site analyses (TSAs) were used to compare the park lakes to...
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PMID: 19479335
PDF is available here.
Abstract
The results of the present study identify a novel organelle in chicken egg yolk comprising acidic vesicles with a morphology, physiology and composition similar to those of acidocalcisomes, within larger acidic vacuoles. The elemental composition of these acidocalcisomes is proportionally similar to...
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PMID: 20196772
PDF is available here.
Abstract
To compare the different expression of protein in RAW264.7 macrophage cells induced by two types of MWNTs (multi-walled carbon nanotubes) with different surface modifications (acid-treated MWNTs and tau-MWNTs modified by taurine).
Treating cells with both types of MWN...
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PMID: 20559414
PDF is available here.
Abstract
In this study, three sulfonated water-soluble polymers based on poly(vinyl alcohol) of different molecular weights (10,000, 50,000 and 100,000 Da) were prepared and tested against commercially available poly(acrylic acid) for the removal of cobalt using polymer assisted ultrafiltration. High rejecti...
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PMID: 20227179
PDF is available here.
Abstract
The facilitated extraction of Cr(VI) through an emulsion liquid membrane (ELM) was investigated, using tributyl phosphate (TBP) as mobile carrier. The emulsion liquid membrane phase consists of kerosene as diluent, TBP as carrier, SPAN 80 as surfactant and (NH(4))(2)CO(3) solution as stripping phase...
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PMID: 20227829
PDF is available here.
Abstract
We present a life cycle assessment of a palm oil production process yielding both biodiesel and cooking oil, incorporating the land-use impact and evaluating the effect of treating the palm oil mill effluent (POME) prior to disposal. The results show that the nonrenewable energy requirement, global...
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PMID: 20496929
PDF is available here.
Abstract
An ultrasonically enhanced two-stage acid leaching process on extracting and recovering multiple heavy metals from actual electroplating sludge was studied in lab tests. It provided an effective technique for separation of valuable metals (Cu, Ni and Zn) from less valuable metals (Fe and Cr) in elec...
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PMID: 20197211
PDF is available here.
Abstract
The adsorption of Pb(2+) ions onto Tunisian clay in aqueous solution was studied in a batch system. Four samples of clay (RGC, RRC, AGC, and ARC) were used. The raw RGC and RRC clays were sampled in jebel Tejera-Esghira in Medenine area (Southeast of Tunisia). AGC and ARC corresponds respectively to...
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PMID: 20189300
PDF is available here.
Abstract
We have developed a combined experimental/computational framework to address this problem and used it to understand the genetic basis of ethanol tolerance in Escherichia coli. We used fitness profiling to measure the consequences of single-locus perturbations in the context of ethanol exposure. A mo...
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PMID: 20531407
PDF is available here.
Abstract
These results show that reduction of acetic acid concentration by an extraction process with raw palm oil methyl ester before re-using stillage improves the number of recycles without a major effect on ethanol production. The proposed process generates a palm oil methyl ester that contains organic a...
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PMID: 19748936
PDF is available here.
Abstract
We quantify over 40 end-products (amines, acids, alcohols, aldehydes, or ketones) produced by malignant neuroblastoma under accelerated glycolysis (+glucose (GLU) supply 1-10 mM) +/- mitochondrial toxin; 1-methyl-4-phenylpyridinium (MPP(+)) to abate aerobic respiration to delineate differences betwe...
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PMID: 19784859
PDF is available here.
Abstract
Human disease processes are often characterized by a deviation from the normal physiological concentration of critical biomarkers. The detection of disease biomarkers requires the development of novel sensing methods which are sensitive, specific, efficient and low-cost. To address this need, the ab...
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PMID: 20174872
PDF is available here.
Abstract
Mild and efficient Fischer esterification reactions of lactic acid with a variety of straight chain aliphatic alcohols, cyclohexanol and benzyl alcohol were successfully performed using two novel Brønsted acidic ionic liquids that bear an aromatic sulfonic acid group on the imidazolium or pyridiniu...
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PMID: 20226709
PDF is available here.
Abstract
These results were consistent with those of 1H-NMR spectroscopy. The effect of beta-CD on the degradation rate was studied in more detail. The apparent first order rate constant for the degradation of AMX in the pH 1.2 solution at 37 degrees C was 0.1121 h(-1) (t(1/2)=6.18 h), which decreased with t...
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PMID: 20519868
PDF is available here.
Abstract
We have shown that aqueous arginine solution increases the solubility of proteins in formulation and purification, suppresses aggregation during refolding and storage and improves performance of column chromatography. Acidic arginine solution now finds application for virus inactivation. I will summ...
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PMID: 20519857
PDF is available here.
Abstract
We evaluated the chronological changes in fecal bacteria and organic acids in 6 patients undergoing autologous stem cell transplantation with quinolone-based chemoprophylaxis. All patients developed grade 2-3 diarrhea. Four patients developed grade 3 febrile neutropenia. The total count of obligator...
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PMID: 20567111
PDF is available here.
Abstract
We investigated surA and fkpA, encoding two different classes of peptidyl-prolyl isomerase that function in folding cell envelope proteins. Both surA and fkpA are members of the heat-shock-inducible sigma(E) regulon of Escherichia coli. Although both genes are expressed in C-starved Salmonella cells...
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PMID: 20232248
PDF is available here.
Abstract
Reductive dissolution of lead dioxide (PbO(2)(s)) has been attributed to a major route leading to elevated lead concentrations in drinking water. However, surface processes involved in this heterogeneous reaction have not been elucidated. In this study, the kinetics and mechanism of reductive dissol...
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PMID: 20420362
PDF is available here.
Abstract
Oximes and alpha-ketoacids undergo an unexpectedly facile and chemoselective annulation to afford 2,5-dihydrooxazole 3-oxides. The resulting cyclic nitrones serve as chemically and configurationally stable masked alpha-ketoacids that can be easily elaborated and manipulated. Deprotection is achieved...
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PMID: 20356071
PDF is available here.
Abstract
We concluded that perfluoropentanoic acid (PFPA) had little effect on BSA. However, perfluorooctanoic acid (PFOA) and perfluorodecanoic acid (PFDA) exhibited remarkable fluorescence quenching, which was attributed to the formation of a moderately strong complex. The enthalpy change (DeltaH) and entr...
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PMID: 20397730
PDF is available here.
Abstract
We identified an arylstibonic acid, NSC13778 that specifically binds to the basic region of the C/EBPalpha B-ZIP domain and disrupts DNA binding. We now examine a panel of 14 additional arylstibonic acid derivatives of NSC13778 for their ability to inhibit the DNA binding of five B-ZIP dimers (c-Fos...
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PMID: 20176111
PDF is available here.
Abstract
We have performed substitution of strongly electron-withdrawing perfluoromethyl (CF(3)) group(s) as heme side chain(s) of Mb to obtain large alterations of the heme electronic structure in order to elucidate the relationship between the O(2) affinity of Mb and the electronic properties of heme perip...
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PMID: 20392104
PDF is available here.
Abstract
FH patients are more sensitive to mechanical or chemical stimuli than NERD patients. Sensitization of esophageal acid-sensitive chemoreceptors may exert a significant influence on the pressure-sensitive mechanoreceptors, and there is the cooperative interaction in the process of esophageal visceral...
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PMID: 20393268
PDF is available here.
Abstract
The iso-alpha-acids, the major contributor to bitter beer taste, is well-known to strongly degrade during beer aging. The storage of beer in brown glass bottles revealed a strong depletion of the trans-configured isomers in a highly specific manner, whereas the corresponding cis-iso-alpha-acids seem...
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PMID: 20222658
PDF is available here.
Abstract
We report that a hard Lewis base substantially affects the reaction efficiency of direct catalytic asymmetric gamma-addition of allyl cyanide (1a) to ketones promoted by a soft Lewis acid/hard Brønsted base catalyst. Mechanistic studies have revealed that Cu/(R,R)-Ph-BPE and Li(OC(6)H(4)-p-OMe) ser...
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PMID: 20337453
PDF is available here.