Abstract
We studied the prevalence and pattern of skin disorders in patients with CRF at The University College Hospital, Ibadan, Nigeria, during the period between May 2006 and February 2007. Relevant information was collected with the aid of a questionnaire. The patients were then examined for skin disorde...
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PMID: 21422624
PDF is available here.
Abstract
We report 6 cases of congenital candidiasis limited to nail plates that had favorable outcome....
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PMID: 20664491
PDF is available here.
Abstract
Outcomes and patient satisfaction were good with a low complication rate resulting in a change of practice in our unit to an 'opt-in' system for follow-up....
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PMID: 20513272
PDF is available here.
Abstract
We sought to review the current literature on the clinical and histologic aspects of onychoheterotopia.
A literature search was performed to evaluate peer-reviewed articles on the topic.
Detailed reports have characterized many features of onychoheterotopia. The various etiology and treatment option...
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PMID: 20724029
PDF is available here.
Abstract
Glomus tumours are benign painful tumours of the glomus body, a thermoregulatory shunt in the digits. Glomus tumours of the fingers and toes are associated with the monogenic disorder neurofibromatosis type 1 (NF1) and are recently recognised as part of the NF1 phenotype.
A multi-institutional exper...
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PMID: 20530151
PDF is available here.
Abstract
Examination of patients for skin lesions of TSC could be improved by including inspection for longitudinal nail grooves, red comets, longitudinal leukonychia, and splinter hemorrhages in addition to ungual fibromas. The anatomic distribution of TSC ungual fibromas is not random and appears consisten...
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PMID: 20462663
PDF is available here.
Abstract
We detail the behavior of each species and document the incorporation of human hair into the portable larval shelters constructed by the caterpillars of T. pellionella. Hair of the decedent used as building material for caterpillar shelters provided enough starting template to amplify and sequence t...
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PMID: 20412363
PDF is available here.
Abstract
There is a general acceptance that cellular material will transfer from one person to another person's fingernails through everyday contact. However, the level or degree of contact required to transfer sufficient cellular material in order to obtain a DNA profile is not known. This study examined sw...
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PMID: 20470738
PDF is available here.
Daniela Rollando,
Gian Paolo Bezante,
Alberto Sulli,
Manrico Balbi,
Nicoletta Panico,
Carmen Pizzorni,
Simone Negrini,
Claudio Brunelli,
Antonio Barsotti,
Maurizio Cutolo,
Francesco Indiveri and
Massimo Ghio
Abstract
FMD was significantly reduced in patients with SSc compared to healthy subjects [median 8.0% (3.0%-9.0%) vs 15.0% (12.0%-16.0%), respectively; p < 0.0001]. Patients with an early pattern of microangiopathy showed reduced FMD values compared to controls (p = 0.0001). FMD was significantly reduced in...
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PMID: 20436078
PDF is available here.
Abstract
FBP was significantly lower in patients with SSc (p < 0.05) compared to controls. Heating of the LDF probe at 36 degrees C induced a significant increase of FBP in all subjects (p < 0.001), but the slope of variation was significantly lower in patients with SSc compared to controls (p < 0.05). Patie...
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PMID: 20436070
PDF is available here.
Abstract
This is the first study to demonstrate reliability of the qualitative and semiquantitative NVC assessment in an SSc cohort between raters at different centres. Reliability of NVC assessment is essential for use of this tool in multicentre SSc trials....
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PMID: 20439291
PDF is available here.
Abstract
Two previously healthy women developed nausea, vomiting, headache and dizziness for several days, a massive hair loss about 2 weeks later and a discoloration of the fingernails. Detailed diagnostic procedures did not reveal any pathological results. Therapeutic measures did not show any effect. Thal...
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PMID: 20106940
PDF is available here.
Abstract
Sonography is a noninvasive imaging method that can reliably detect common benign tumors and pseudotumors of the nail and provide precise data about their characteristics. This imaging modality can support diagnosis and surgery and can allow a better definition and improvement of the cosmetic outcom...
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PMID: 20427793
PDF is available here.
Abstract
Nailfold microcirculation as determined by semiquantitative simple capillaroscopy appears to provide useful information in patients with idiopathic inflammatory myopathy, contributing to an early diagnosis and identifying patients with a poor prognosis.
Copyright 2010 Elsevier Inc. All rights reserv...
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PMID: 19022479
PDF is available here.
Abstract
Raman spectra of human nail clippings from various sources were collected and then deconvoluted to obtain the pure component spectra of the underlying constituents present. This blind-deconvolution was performed using a self-modeling curve resolution technique, namely band-target entropy minimizatio...
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PMID: 20152394
PDF is available here.
Abstract
The diagnosis of onychodystrophy has increased in dermatology consultation. This could be due to its esthetic effect, pain or disability, physician awareness for detecting the disease in the context of dermatologic or systemic diseases, or a greater incidence. One of the first differential diagnoses...
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PMID: 20347659
PDF is available here.
Abstract
Carbon monoxide is a component of motor vehicle exhaust fumes, provided a functional catalytic converter is not present. This gas binds avidly to the hemoglobin molecule in red blood cells preventing its oxygen transport function, effectively poisoning the body by starving it of oxygen. In binding t...
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PMID: 19882310
PDF is available here.
Abstract
Reports of foreign bodies in the oral cavity are few in number. Three cases of children of varying ages, presenting with oral foreign bodies, and their subsequent diagnosis and management, are described. The importance of considering foreign bodies, as part of a differential diagnosis in paediatric...
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PMID: 20527577
PDF is available here.
Abstract
We describe its spatiotemporal expression pattern outside the hair follicle during human cutaneous embryogenesis.
We examined immunohistochemically samples from embryonic and fetal human skin for the expression of SOX9 using standard techniques. For comparison reasons, we also includ...
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PMID: 19614725
PDF is available here.
Abstract
We used standard immunohistochemical methods to examine Blimp-1 expression in samples from embryonic, fetal and adult human skin and in 119 sebaceous lesions comprising all major categories of sebocytic lineage, including hamartomas, cysts and benign and malignant neoplasms.
Blimp-1...
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PMID: 19788443
PDF is available here.
Abstract
Studies have shown that various antioxidants are decreased in different age-related degenerative diseases and thus, oxidative stress would have a central role in the pathogenesis of many disorders that involve neuronal degeneration, including Alzheimer's disease (AD). The present study aimed to asse...
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PMID: 19948078
PDF is available here.
Abstract
Exposure of fingernails and toenails to ionizing radiation creates radicals that are stable over a relatively long period (days to weeks) and characterized by an isotropic EPR signal at g = 2.003 (so-called radiation-induced signal, RIS). This signal in readily obtained fingernail parings has the po...
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PMID: 20065699
PDF is available here.
Abstract
We employ these results in the context of so-called shared-parameter models where outcome and missingness models are connected by means of common latent variables or random effects, to devise a sensitivity analysis framework. Precisely, the impact of varying unverifiable assumptions about unobserved...
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PMID: 19937996
PDF is available here.
Abstract
Topical therapy is highly desirable in treating nail disorders due to its localized effects, which results in minimal adverse systemic events and possibly improved adherence. However, the effectiveness of topical therapies is limited by minimal drug permeability through the nail plate. Current resea...
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PMID: 19819318
PDF is available here.
Abstract
Abstract: Tolnaftate, an antifungal of thiocarbamate class, is used topically in 1% formulations. Its penetration into skin layers is a prerequisite for tolnaftate action against dermatophytes. The aim of this work was to optimize and validate a simple, rapid, accurate and reproducible procedure for...
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PMID: 20635527
PDF is available here.
Abstract
Pincer nail has been confused with ingrown nail for decades.
The objectives were to analyze the circumferential length of pincer nail and the relationship between nail deformity and the underlying distal phalangeal shape.
The circumferential length of...
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PMID: 19889164
PDF is available here.
Abstract
The present study indicates a relationship between ONH and finger blood flow in subjects with PVD. This might be an indirect sign of a disturbed autoregulation of ocular blood flow in PVD subjects....
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PMID: 19882525
PDF is available here.
Abstract
We report 1 patient with pustular psoriasis and ACH whom we have treated successfully with etanercept (for 30 months) and then adalimumab (for 13 months and ongoing). Blanching was initially achieved with etanercept 50 mg twice a week, but suppression of periungual inflammation then required combina...
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PMID: 20110631
PDF is available here.
Abstract
Between March and October 2008, the nails of 541 (252 females, 289 males) consecutively born neonates with an average age of 3.2 days were examined in the Neonatology Unit. Of these newborns with nail disorders, 36 were re-examined after a period that ranged from seven days to six months. The most f...
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PMID: 20579456
PDF is available here.
Abstract
Testing for drugs of abuse has become commonplace and is used for a variety of indications. Commonly employed testing methods include immunoassay and chromatography. Testing methods vary in their sensitivity, specificity, time, and cost. While urine remains the most common body fluid used for testin...
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PMID: 20358693
PDF is available here.
Abstract
Fingertip injuries are commonly seen by family and emergency physicians. Many of the cases are simple to treat and do not need specialised treatment by a hand surgeon. However, there are certain conditions where early intervention by a hand surgeon is warranted for better functional and aesthetic ou...
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PMID: 20200781
PDF is available here.
Abstract
NARRATIVE REVIEW: The following review discusses the more common disorders of the perionychium and skin likely to be observed by the hand therapist. To assist the therapist in recognition of abnormalities, the anatomy, physiology, and basic function of the normal nail unit are described. Indications...
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PMID: 20304604
PDF is available here.
Abstract
Fingernail has been suggested as a biomarker of fluoride (F) body burden, but there is no consensus if it would be a reliable indicator of F exposure from dentifrice. Therefore, the present study was conducted to investigate if fingernails would have sensitivity to detect F exposure from dentifrice...
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PMID: 20640353
PDF is available here.
Sujuan Gao,
Yinlong Jin,
Kathleen S Hall,
Chaoke Liang,
Frederick W Unverzagt,
Feng Ma,
Yibin Cheng,
Jianzhao Shen,
Jingxiang Cao,
Janetta Matesan,
Ping Li,
Jianchao Bian,
Hugh C Hendrie and
Jill R Murrell
Abstract
Future studies are needed to examine the mechanism underlying the association between the apoE epsilon4 allele and Se levels, including the role of oxidative stress and that of reduced lipid metabolism in the apoE epsilon4 carriers....
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PMID: 19278567
PDF is available here.
Abstract
Arsenic exposure was associated with small-cell and squamous-cell carcinoma of the lung [OR = 2.75; 95% confidence interval (CI), 1.00-7.57] for toenail arsenic concentration > or = 0.114 microg/g, versus < 0.05 microg/g. A history of lung disease (bronchitis, chronic obstructive pulmonary disease,...
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PMID: 20049123
PDF is available here.
Abstract
We report an infant who had clinical features consistent with pachyonychia congenita type II, with unusual features of microcephaly, seizures, electroencephalogram abnormalities, failure to thrive, and heterochromia iridis....
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PMID: 19887695
PDF is available here.
Abstract
These results were confirmed in plasma samples from 84 patients undergoing gastro-oesophageal endoscopy. Differences between 25 smokers and 59 non-smokers are again much lower for myosmine (0.30 ± 0.35 vs 0.16 ± 0.18 ng ml
-1,
p <0.05) than for cotinine (54.67 ± 29.63 vs 0.61...
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PMID: 19476410
PDF is available here.
Abstract
The aim of this study is to describe by video-nailfold capillaroscopy the microvascular involvement and capillary changes in children with Henoch-Schönlein purpura (HSp) and to establish a possible correlation with clinical outcome. Thirty-one patients underwent capillaroscopic evaluation through a...
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PMID: 19462155
PDF is available here.
Abstract
Onychomycosis is a fungal infection of the nails with broad aetiological scope, and it represents 18-40% of all onychopathies and 39% of all superficial mycotic infections. From July 1996 to December 1999, samples of nails were collected from 588 patients with presumptive diagnosis of onychomycosis...
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PMID: 19424818
PDF is available here.
Ernesto E Soscia,
Raffaele R Scarpa,
Marco Amedeo MA Cimmino,
Mariangela M Atteno,
Rosario R Peluso,
Cesare C Sirignano,
Luisa L Costa,
Salvatore S Iervolino,
Francesco F Caso,
Antonio A Del Puente,
Marco M Salvatore and
Andrea A Soricelli
Abstract
We discuss the advantages and problems related to the use of low- and high-field MRI in the study of the nail unit of patients with PsA....
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PMID: 19661539
PDF is available here.
Abstract
Mycosis of foot or finger nails (onychomycosis) is the second most common fungal skin infection in industrialized countries. In Germany, estimated 10 to 17% of the total adult population and almost one half of all people beyond the age of 65 are suffering from an onychomycosis. In most cases, mycose...
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PMID: 19777736
PDF is available here.
Abstract
We report a case of subungual exostosis located at the hallux in a 14-year-old boy suffering from subungual exostosis of the hallux that presented the characteristic triad of this entity: subungular tumor with nail plate deformity, digital pain and radiologic typical findings....
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PMID: 19753444
PDF is available here.
Abstract
We investigated the prevalence of onychomycosis and tinea pedis in patients with psoriasis compared to control group. A total of 60 patients with psoriasis (27 male, 33 female; mean age: 40.8 +/- 17.6 years) and 60 subjects without psoriasis (27 male, 33 female; mean age: 42.8 +/- 17.3 years) who we...
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PMID: 19795619
PDF is available here.
Abstract
All flaps survived. Wound healed in one-stage in 5 cases, and healed in second stage in 1 case because of swelling. All skin grafting at donor site survived in one-stage. All patients were followed up for 6-8 months. The appearance of flaps were good, and the two-point discrimination was 5-6 mm. Bon...
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PMID: 19514581
PDF is available here.
Abstract
We have recently demonstrated that cathepsin L is the elusive processing and activating protease for transglutaminase 3, an enzyme that is responsible for crosslinking of structural proteins in cornified envelope formation. Here, we study the localization of all players of this pathway in the human...
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PMID: 19005484
PDF is available here.
Abstract
We performed nailfold capillaroscopy in 128 randomly selected patients fulfilling the international classification criteria for BD. Capillaroscopy was done in eight fingers with a x3.2 microscopy. All patients were questioned for history of Raynaud's phenomenon, ischemic ulcers, smoking, and hyperte...
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PMID: 19219480
PDF is available here.