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Welcome to the Pubget Medical Subject Headings (MESH) browser. Click on a topic or subtopic below to explore related papers. In the gold box is the most recent paper about the current MESH term, and below are 20 related papers.
Randomized Controlled Trials as Topic (0):
Recent article
Randomized Controlled Trials as Topic
Abstract
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Abstract
MMW Fortschritte der Medizin (153)41 2011
Abstract
Ideggyogyaszati szemle (64)9-10 2011
Abstract
The deep brain stimulation (DBS) is an emerging treatment option in brain disorders in which randomized multicenter trials proved its efficacy leading to licensing different DBS methods in various brain diseases. More recently more and more brain structures have become candidates for...
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PMID: 22059367
PDF is available here.
PDF is available here.
Abstract
Presse Medicale (40)11 2011
Abstract
Clinical studies of the last 15years have shown the benefit of pharmacological interventions on the progression of chronic kidney disease, confirming the concept of nephroprotection. Pharmacological blockade of the renin angiotensin system remains the cornerstone of the nephroprotect...
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PMID: 21981881
PDF is available here.
PDF is available here.
Presse Medicale (40)11 2011
Abstract
Benfluorex is responsible of restrictive organic valvular regurgitations via one of its metabolites, the norfenfluramine. It has been withdrawn from the european market in June 2010. In France, about five millions of people have been exposed to benfluorex since its market launch in 1...
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PMID: 21981882
PDF is available here.
PDF is available here.
Abstract
About 190,000 Germans experience a myocardial infarction each year. Of these, 25% may be eligible for an implantable cardioverter defibrillator (ICD) due to low left ventricular ejection fraction. Given the high costs of implantation, the purpose of this study was to assess the cost-effectiveness of...
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PMID: 21914500
PDF is available here.
PDF is available here.
Abstract
Hemodynamic control can improve the outcome of surgery. Esophageal Doppler monitoring measures blood flow by ultrasound waves. This work investigates the cost-effectiveness of this procedure during colorectal resection.
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PMID: 21914501
PDF is available here.
PDF is available here.
Abstract
MMW Fortschritte der Medizin (153)36 2011
Abstract
MMW Fortschritte der Medizin (153)36 2011
Abstract
Abstract
Extending intravenous thrombolysis to a broader patient population, clarifying the risk and benefits of intra-arterial reperfusion therapies, and further development of neuroprotective therapies were the key recommendations from STAIR VII....
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PMID: 21852620
PDF is available here.
PDF is available here.
Abstract
Abstract
Background School-based interventions are thought to be the most universally applicable and effective way to counteract low physical activity (PA) and fitness although there is controversy about the optimal strategy to intervene. Objectives The objective of this review was to summarise recent reviews...
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PMID: 21836176
PDF is available here.
PDF is available here.
Abstract
This paper in the series from the World Congress of Gastroenterology addresses the safety and immunogenicity of biological therapy. The safety profile in randomized controlled studies of all biological agents in Crohn's disease (CD) and ulcerative colitis has been generally favorable...
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PMID: 21844919
PDF is available here.
PDF is available here.
Abstract
This paper in the series from the World Congress of Gastroenterology addresses the safety and immunogenicity of biological therapy. The safety profile in randomized controlled studies of all biological agents in Crohn's disease (CD) and ulcerative colitis has been generally favorable...
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PMID: 21844919
PDF is available here.
PDF is available here.
Nippon Geka Gakkai zasshi (112)5 2011
Abstract
Although laparoscopic colon cancer surgery is widely accepted as a feasible alternative to open surgery, there is still limited evidence on the use of the laparoscopic approach for rectal cancer. Although laparoscopic rectal surgery is a technically demanding procedure with a steep l...
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PMID: 21941824
PDF is available here.
PDF is available here.
Nippon Geka Gakkai zasshi (112)5 2011
Abstract
Lateral lymphatics of the rectum originate in the area where branches of the inferior hypogastric plexus and the middle rectal vessels from the internal iliac vessels enter the mesorectum below the level of the peritoneal reflection in the pelvis, then reach the bifurcation of iliac...
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PMID: 21941823
PDF is available here.
PDF is available here.
Clinical Nephrology (76)3 2011
Abstract
Cinacalcet lowers plasma iPTH and serum P, Ca and Ca × P levels in dialysis patients with SHPT, regardless of disease severity. Patients with more severe disease experienced greater reductions in PTH and P, but fewer achieved iPTH ≤ 250 pg/ml by the efficacy assessment phase. Use of cinacalcet wh...
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PMID: 21888861
PDF is available here.
PDF is available here.
Abstract
We are therefore at a juncture where a reduction of LR may be achieved by tumor resection with wide margins, but data regarding optimal margin width are conflicting and the risk/benefit balance of tumorectomy with wide margins has not been demonstrated. A randomized trial of reexcision for close mar...
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PMID: 22010383
PDF is available here.
PDF is available here.
Abstract
I studies. Significant progress has been made in the last 2 years both in the development of novel immunobiologics such as CARs, and in establishing survival benefits of an anti-GD2 monoclonal antibody in randomized studies. Although there is much excitement going forward, a great deal of laboratory...
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PMID: 21854215
PDF is available here.
PDF is available here.
Prescrire international (20)119 2011
Abstract
Management of episodes of herpes labialis (cold sores) in otherwise healthy individuals is mainly based on hygiene measures intended to avoid transmitting the virus. At best, topical treatment with aciclovir, an antiviral drug, simply reduces the duration of the episode. A cream cont...
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PMID: 21954513
PDF is available here.
PDF is available here.
Abstract
We have reviewed the current literature regarding the use of prehabilitation and rehabilitation in relation to major surgery in elderly patients. We have focussed particularly on randomised controlled trials, systematic reviews and meta-analyses. There is currently a paucity of high-quality clinical...
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PMID: 21925410
PDF is available here.
PDF is available here.
Abstract
We systematically searched currently available randomized controlled trials that compared the effects of MLs and SVLs in children. A meta-analysis of nine of these trials showed that MLs with powers ranging from +1.50 to +2.00D were associated with a statistically significantly decrease in myopia pr...
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PMID: 21813146
PDF is available here.
PDF is available here.
Abstract
Abstract
We summarize the design, efficacy, and safety of previous randomized controlled trials and propose adapted algorithms for US settings. We performed a systematic search and included all 14 randomized controlled trials (N = 4467 patients) that investigated procalcitonin algorithms for antibiotic treat...
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PMID: 21824946
PDF is available here.
PDF is available here.
Abstract
The aim of this study was to describe international enrollment and participation in National Institutes of Health (NIH)-sponsored cardiovascular randomized controlled trials (RCTs).
RCTs provide the evidence base for major societal guidelines and profoundly influence...
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PMID: 21816301
PDF is available here.
PDF is available here.
Archives of Ophthalmology (129)8 2011
Abstract
Abstract
Germ cell tumors are cured by cisplatin-based chemotherapy and secondary surgery. Patients with initial poor response to chemotherapy and relapsed disease patients have poor prognosis. Among different therapeutic approaches high dose chemotherapy with hematopoietic stem cell support has been studied....
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PMID: 21821481
PDF is available here.
PDF is available here.
Abstract
We searched MEDLINE (January 1, 1950, through October 31, 2010), Agricola (January 1, 1970, through October 31, 2010), Scopus (January 1, 1996, through October 31, 2010), and the Cochrane Central Register of Controlled Trials (through October 31, 2010) for randomized controlled trials in human being...
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PMID: 21802563
PDF is available here.
PDF is available here.
Abstract
To assess the therapeutic effects and safety of different doses of immunoglobulin in the treatment of Kawasaki disease.
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PMID: 21849113
PDF is available here.
PDF is available here.
Abstract
Systemic lupus erythematosus (SLE) is an autoimmune disease that disproportionately affects women of childbearing age during their most productive years. Current therapeutic measures have improved patient survival; however, the impact of interventions on general and specific domains...
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PMID: 21633837
PDF is available here.
PDF is available here.
Abstract
We conducted a systematic review and meta-analysis to evaluate the efficacy of isolated aerobic exercise programs in overweight and obese populations....
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PMID: 21787904
PDF is available here.
PDF is available here.
Abstract
To determine all cause mortality and deaths from cardiovascular events related to intensive glucose lowering treatment in people with type 2 diabetes.
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PMID: 21791495
PDF is available here.
PDF is available here.
Abstract
MMW Fortschritte der Medizin (153)29-31 2011
Abstract
Abstract
Abstract
Introduction: The knowledge base of drug-induced liver injury (DILI) continues to grow each year as additional drugs are identified as hepatotoxins. There is still a need to improve our ability to predict and diagnose DILI in the preclinical and post-approval settings. Areas covered:...
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PMID: 21510822
PDF is available here.
PDF is available here.
Pflege Zeitschrift (64)7 2011
Abstract
Abstract
Abstract
Abstract
• To systematically review the literature on gemcitabine chemotherapy for advanced or metastatic bladder cancer.
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PMID: 21718430
PDF is available here.
PDF is available here.
Abstract
Abstract
Skeletonization of the internal thoracic artery is supposed to achieve extra length with added advantages of decreased sternal complications. There is no agreement whether skeletonization affects grafts, main adverse cardiac events, mortality, or pulmonary function when compared with the conventional...
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PMID: 21718830
PDF is available here.
PDF is available here.
Abstract
Oral Oncology (47)9 2011
Abstract
Abstract
Dose-effect relationship data suggest that short-term psychotherapy is insufficient for many patients with chronic distress or personality disorders (complex mental disorders).
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PMID: 21719877
PDF is available here.
PDF is available here.
The case for early intervention in anorexia nervosa: theoretical exploration of maintaining factors.
Abstract
We revisit and reinterpret the original study in which the so-called 'Maudsley (London) model' of family therapy was compared with individual therapy for anorexia nervosa. Family therapy was more effective in adolescents with a short duration of illness. However, this is only part of the story. A la...
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PMID: 21719874
PDF is available here.
PDF is available here.
Abstract
MMW Fortschritte der Medizin (153)23 2011
Abstract
Minerva ginecologica (63)3 2011
Abstract
Neoadjuvant chemotherapy for primary breast cancer is the gold standard in the treatment of locally advanced, inoperable breast cancer, but based on a large body of evidence has become a standard treatment option for patients with operable disease, who are clear candidates for adjuvant chemotherapy....
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PMID: 21654611
PDF is available here.
PDF is available here.
Abstract
Cytokines were the only drugs proven to be effective for advanced renal cell carcinoma(RCC). Introducing the targeted drugs prolonged patients' survival. However, limited high-quality evidence is now available for second-line treatment. Everolimus is effective for patients who have experienced progre...
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PMID: 21677480
PDF is available here.
PDF is available here.
Abstract
Abstract
Because it is unusual to find sufficient evidence from RCTs to answer all key questions concerning benefit or the balance of benefits and harms, comparative effectiveness reviewers should routinely assess the appropriateness of inclusion of observational studies for questions of benefit. Furthermore...
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PMID: 21636246
PDF is available here.
PDF is available here.
Abstract
Abstract. The therapeutic efficacies of 3-day regimens of artesunate-amodiaquine and artemether-lumefantrine during 5 years of adoption as first-line treatments were evaluated in 811 ≤ 12-year-old malarious children. Compared with artemether-lumefantrine, amodiaquine-artesunate sig...
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PMID: 21633031
PDF is available here.
PDF is available here.
Abstract
Abstract
Abstract
Background Studies from the Women's Health Initiative have reported an increased risk of breast cancer in users of estrogen plus progestogen. Among users of estrogen alone an increased risk was not observed. Objective To evaluate the evidence for unopposed estrogen. Methods In a rela...
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PMID: 21642263
PDF is available here.
PDF is available here.
Abstract