Abstract
Our results also show that this replacement may change the strain energy distribution within the bone. Based on a semi-mechanistic bone remodeling theory, it is speculated that this alteration in strain energy distribution in artificial bone can destabilize normal bone remodeling process, and theref...
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PMID: 21870458
PDF is available here.
Abstract
We analyzed the response of a stenotic trachea after a stent implantation. An endotracheal stent is the common treatment for tracheal diseases such as stenosis, chronic cough, or dispnoea episodes. Medical treatment and surgical techniques are still challenging due to the difficulties in overcoming...
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PMID: 21823742
PDF is available here.
Abstract
The two-way insertion loss of a 1 m length of waveguide was reduced by nearly 5 dB over a 4% bandwidth at W-band (94 GHz) for an electron paramagnetic resonance (EPR) spectrometer relative to WR10 waveguide. The waveguide has an oversize section of commercially available rectangular WR28 and a novel...
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PMID: 21806211
PDF is available here.
Abstract
Our aim was to compare different magnet arrangements for magnetic cell delivery to human lower leg arteries and investigate the theoretical targeting efficiency under realistic flow conditions as a possible treatment after angioplasty. Additionally the potential of scaling down or translating the ma...
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PMID: 21858990
PDF is available here.
Abstract
The control of the mechanical stimuli transmitted to the cells is critical for the design of functional scaffolds for tissue engineering. The objective of this study was to investigate the dynamics of the mechanical stimuli transmitted to the cells during tissue differentiation in an...
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PMID: 20865437
PDF is available here.
Abstract
Neuroprostheses based on electrical stimulation could potentially help disabled persons. They are based on neural interface that aim at creating an intimate contact with neural cells. The efficacy of neuroprostheses can be improved by increasing the selectivity of the neural interfac...
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PMID: 21693427
PDF is available here.
Abstract
Water ordering near a charged membrane surface is important for many biological processes such as binding of ligands to a membrane or transport of ions across it. In this work, the mean-field Poisson-Boltzmann theory for point-like ions, describing an electrolyte solution in contact...
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PMID: 21613667
PDF is available here.
Abstract
This study introduces the use of high-frequency pulsed electric fields for tissue electroporation. Through the development of finite element models and the use of analytical techniques, electroporation with rectangular, bipolar pulses is investigated. The electric field and temperature distribution a...
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PMID: 21189230
PDF is available here.
Abstract
The superposition of acoustical modes radiated from a transducer can provide directionality from a compact projector. This paper presents the foundation, as well as examples, of piezoelectric ceramic, piezoelectric single crystal, and magnetostrictive versions of this "modal projector." Measured and...
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PMID: 21476644
PDF is available here.
Abstract
A finite-element (FE) model of human skin is proposed for future use in an interactive real-time surgical simulation to teach surgeons procedures, such as facial reconstruction using skin-flap repair. For this procedure, skin is cut into flaps that are stretched to cover openings in the face. Thus, t...
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PMID: 20172812
PDF is available here.
Abstract
This paper proposes a new method of rapidly deriving the transfer matrix for the boundary element method (BEM) forward problem from a tailored female torso geometry in the clinical setting. The method allows rapid calculation of epicardial potentials (EP) from body surface potentials (BSP). The use o...
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PMID: 21095854
PDF is available here.
Abstract
We propose a novel technique for computing shape functions of finite elements (FEs). The technique generates macro FEs (MFEs) based on the local decomposition of elements into tetrahedral subelements with linear shape functions. Such an approach necessitates the direct use of hybrid meshes (HMs) com...
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PMID: 20699206
PDF is available here.
Abstract
We overcame this limitation in a previous study by combining the phantom with a finite-element (FE) mechanical model of the left ventricle (LV) capable of more realistically simulating regional defects caused by ischemia. In the present work, we extend this model giving it the ability to accurately...
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PMID: 21041157
PDF is available here.
Abstract
This study examined the effect of PTH and alendronate alone and in combination on the bone architecture, mineralization, and estimated mechanics in the OVX rat. Female Wistar rats aged 7-9months were assigned to one of five groups: (1) sham+vehicle, (2) OVX+vehicle, (3) OVX+PTH, (4)...
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PMID: 21515436
PDF is available here.
Abstract
In electromagnetic dosimetry, anatomical human models are commonly obtained by segmentation of magnetic resonance imaging or computed tomography scans. In this paper, a human head model extracted from thermal infrared images is examined in terms of its applicability to specific absorption rate (SAR)...
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PMID: 21480080
PDF is available here.
Abstract
Biomechanical models that describe soft tissue deformation provide a relatively inexpensive way to correct registration errors in image-guided neurosurgical systems caused by nonrigid brain shift. Quantifying the factors that cause this deformation to sufficient precision is a challenging task. To ci...
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PMID: 21097376
PDF is available here.
Abstract
This paper proposes a method of parametric representation and functional measurement of 3-D cardiac shapes in a deformable nonuniform rational B-splines (NURBS) model. This representation makes it very easy to automatically evaluate the functional parameters and myocardial kinetics of the heart, sinc...
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PMID: 20952325
PDF is available here.
Abstract
The authors conducted a study to analyze the stress concentration areas in a tooth restored with a post-retained crown under various conditions. Materials and
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PMID: 21357863
PDF is available here.
Abstract
We propose a finite-element method (FEM)-based 3-D tumor growth prediction system using longitudinal kidney tumor images. To the best of our knowledge, this is the first kidney tumor growth prediction system. The kidney tissues are classified into three types: renal cortex, renal medulla, and renal...
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PMID: 21342810
PDF is available here.
Abstract
To investigate the level and distribution of stresses in composite-restored mandibular first molars with various combinations of base materials.
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PMID: 21469399
PDF is available here.
Abstract
We demonstrate an optically powered microelectromechanical system (MEMS) transducer. It was designed and fabricated using MEMS techniques, and can generate narrowband ultrasonic bulk waves from a broadband laser excitation pulse with high efficiency. The transducer is a two-mask-level MEMS device wi...
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PMID: 21342832
PDF is available here.
Abstract
Rapid prototyping techniques are widely used to fabricate well-defined three-dimensional structures of tissue homologs. The piston-assisted microsyringe (PAM2) is a rapid prototyping technology specifically developed for low-shear stress extrusion of viscous hydrogel solutions contai...
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PMID: 20799910
PDF is available here.
Abstract
This study evaluated the risk of failure for an endodontically treated premolar with MOD preparation and three CEREC ceramic restoration configurations.
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PMID: 21227485
PDF is available here.
Abstract
We report a methodology for selecting scaffolds with different permeabilities and surface area/volume ratios that can be used to house a 3D cell aggregate. Such a system can be modeled if the consumption or production rates for metabolites and waste products, respectively and the diffusion coefficie...
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PMID: 21312372
PDF is available here.
Abstract
We call this method Rough PCA. The proposed method is successfully applied for choosing the principal features and then applying the Upper and Lower Approximations to find the reduced set of features from a gene expression data....
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PMID: 21431550
PDF is available here.
Abstract
Insufficient coronal tooth structure may require restoration of endodontically treated (ET) teeth with cast posts and cores (CPCs). The prognosis for these teeth is a matter of scientific debate, especially if they serve as distal abutments in cantilever fixed dental prostheses (FDPs). The purpose of...
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PMID: 21479276
PDF is available here.
Abstract
This study formulates a theory for multigenerational interstitial growth of biological tissues whereby each generation has a distinct reference configuration determined at the time of its deposition. In this model, the solid matrix of a growing tissue consists of a multiplicity of in...
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PMID: 20238138
PDF is available here.
Abstract
The controlled cortical impact (CCI) model is widely used in many laboratories to study traumatic brain injury (TBI). Although external impact parameters during CCI tests could be clearly defined, little is known about the internal tissue-level mechanical responses of the rat brain....
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PMID: 20372960
PDF is available here.
Abstract
We have demonstrated that 0.4 and 1 μm beads conjugated with antibodies can be rapidly assembled into the microwells by applying a pulsed electric field across the chamber. By assembling step-wise a mixture of fluorescently labeled antibody-conjugated microbeads, we incorporated both spatial and fl...
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PMID: 20820631
PDF is available here.
Abstract
We study the geometry of biopolymer networks and effects of the geometry on bulk mechanical properties. It is shown numerically that the physical network geometry can be quantified statistically and regenerated from its statistical description, so that the regenerated network exhibits the same netwo...
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PMID: 21230498
PDF is available here.
Abstract
An improved approach for electrical impedance tomography (EIT) image reconstruction, based on modifying the forward and inverse solutions, is proposed. In this approach, the EIT forward problem is solved via the finite element method (FEM) using two types of elements. The inverse problem is solved b...
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PMID: 20938064
PDF is available here.
Abstract
Interspinous devices are widely used for the treatment of lumbar stenosis. The DIAM spinal stabilization system (Medtronic, Ltd.) is an interspinous implant made of silicone and secured in place with 2 laces. The device can be implanted via posterior access with the sacrifice of the supraspinous lig...
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PMID: 21039145
PDF is available here.
Abstract
The effect of polymer infiltration on the compressive strength of β-tricalcium phosphate (TCP) scaffolds fabricated by robocasting (direct write assembly) is analyzed in this work. Porous structures consisting of a tetragonal three-dimensional mesh of interpenetrating rods were fabr...
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PMID: 20566307
PDF is available here.
Abstract
High porosity and pore interconnectivity are important features of a successful tissue engineering scaffold. The objective of this work was to optimize the pore interconnectivity and to increase the porosity of an elastomeric degradable/polar/hydrophobic/ionic (D-PHI) polyurethane po...
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PMID: 20601230
PDF is available here.
Abstract
Biomechanical stresses play an important role in determining plaque stability. Quantification of these simulated stresses can be potentially used to assess plaque vulnerability and differentiate different patient groups.
54 asymptomatic and 45 acutely symptomatic patients underwent in vivo multicont...
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PMID: 20834184
PDF is available here.
Abstract
These results are in qualitative concordance with experimental results previously reported by other authors. Although the model is a simplified version of the biological process of coagulation, the results here obtained justify the mathematical formulation implemented. It is concluded that the model...
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PMID: 20810103
PDF is available here.
Abstract
We aimed to assess critical stresses at FC(MIN) and the maximum lumen curvature over FC (LC(MAX)) and quantify the difference to see which vulnerable site had the highest critical stress and was, therefore, at highest risk of rupture. One hundred patients underwent high resolution carotid magnetic r...
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PMID: 20499180
PDF is available here.
Abstract
To evaluate the effect of the stabilization of the Coflex device on the biomechanical behavior of the instrumented and adjacent spinal segments.
The study was carried out at the Department of Orthopedics, Shanghai Institute of Traumatology and Orthopedics, Ruijin Hospital, Shanghai, China between Se...
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PMID: 20953529
PDF is available here.
Abstract
To assess under load the biomechanical behavior of the cementing system of feldspathic vs alumina porcelain veneers.
A 3D model of a maxillary central incisor, the periodontal ligament (PDL) and the alveolar bone was generated. Incisors restored with alumina and feldspathic porcelain veneers were co...
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PMID: 20157681
PDF is available here.
Abstract
This study proposes a novel hybrid total knee replacement (TKR) design to improve stress transfer to bone in the distal femur and, thereby, reduce stress shielding and consequent bone loss. Three-dimensional finite element (FE) models were developed for a standard and a hybrid TKR and validated expe...
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PMID: 21138239
PDF is available here.
Abstract
Diamond burs with different grit sizes are often applied to adjust ceramic prostheses in restorative dentistry. However, the quantitative influence of diamond grit size on subsurface damage in adjusting ceramic prostheses is unknown. The aim of this study was to investigate and visualize the quantit...
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PMID: 21138236
PDF is available here.
Abstract
We apply the transformation optical technique to modify or improve conventional refractive and gradient index optical imaging devices. In particular, when it is known that a detector will terminate the paths of rays over some surface, more freedom is available in the transformation approach, since t...
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PMID: 20941020
PDF is available here.
Abstract
During the last few years a quite large number of fluorescence imaging applications have been reported in the literature, as one of the most challenging problems in medical imaging is to "see" a tumor embedded in tissue, which is a turbid medium. This problem has not been fully encountered yet, due...
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PMID: 20060682
PDF is available here.
Abstract
This paper reports the design analysis of a microfabricatable mid-infrared (mid-IR) surface plasmon resonance (SPR) sensor platform. The proposed platform has periodic heavily doped profiles implanted into intrinsic silicon and a thin gold layer deposited on top, making a physically flat grating SPR...
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PMID: 20940835
PDF is available here.
Abstract
We demonstrate the design, fabrication and experimental characterization of a submicron-scale silicon waveguide that is fabricated by local oxidation of silicon. The use of local oxidation process allows defining the waveguide geometry and obtaining smooth sidewalls. The process can be tuned to prec...
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PMID: 20940751
PDF is available here.
Abstract
The bronchial tree has little effect on the global deformation and the accuracy of deformable image registration of lungs. Hence, the homogenous model is a reasonable assumption. Since there are some local deformation differences between nodes as the material properties of the bronchial tree change...
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PMID: 20964173
PDF is available here.
Abstract
This project studies the effect of high-performance polyethylene (HPPE) fibers on stress distributions in a maxillary denture and the influence of fiber position on improving denture performance.
A denture was scanned with a 3D Advanced Topometric Sensor digitizing system. The measuring system conve...
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PMID: 20542552
PDF is available here.
Abstract
Fluorescence molecular imaging/tomography may play an important future role in preclinical research and clinical diagnostics. Time- and frequency-domain fluorescence imaging can acquire more measurement information than the continuous wave (CW) counterpart, improving the image quality of fluorescenc...
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PMID: 20671350
PDF is available here.
Abstract
We report detailed quantitative measurements of the mechanical response of nanosized protein shells (viral capsids) to large-scale physical deformations and compare them with theoretical descriptions from continuum elastic modeling and molecular dynamics (MD). Specifically, we used nanoindentation b...
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PMID: 20713001
PDF is available here.
Abstract
We used a finite element method to evaluate the maximum Von Mises stresses in jaw bones of immediately loaded implant with different thread heights and widths, and the maximum displacements in implant-abutment complex. The implant thread height ranged from 0.20 to 0.60 mm, and the thread width range...
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PMID: 20599193
PDF is available here.
Abstract
The results have demonstrated that the new optimized plate is a hybrid of fixation hardware with the small profile of the smallest miniplate configuration and the superior fixation strength and safety that exceeds that of the larger fracture plate configuration.
Copyright 2010 American Association o...
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PMID: 20537782
PDF is available here.
Abstract
Distal forearm fracture is one of the most frequently observed osteoporotic fractures, which may occur as a result of low energy falls such as falls from a standing height and may be linked to the osteoporotic nature of the bone, especially in the elderly. In order to prevent the occurrence of radiu...
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PMID: 20670056
PDF is available here.
Abstract
A finite element model was developed for numerical simulations of nanoindentation tests on cortical bone. The model allows for anisotropic elastic and post-yield behavior of the tissue. The material model for the post-yield behavior was obtained through a suitable linear transformation of the stress...
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PMID: 20670057
PDF is available here.
Abstract
The cross-sectional design has a greater impact than taper or size of the instrument on the stresses developed in the instrument under either torsion or bending. Certain cross-sectional configurations are prone to fracture by excess torsional stresses.
Copyright 2010 American Association of Endodo...
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PMID: 20647104
PDF is available here.
Abstract
The two simulated conditions highlighted the different mechanical properties of the files; the SystemGT showed slightly better performances under flexural solicitation, whereas the Protaper presented better behavior under torsion solicitations.
Copyright 2010 American Association of Endodontists. P...
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PMID: 20647101
PDF is available here.
Abstract
This study presents a finite element-based computational model to simulate the three-dimensional deformation of a breast and fibroglandular tissues under compression. The simulation was based on 3D MR images of the breast, and craniocaudal and mediolateral oblique compression, as used in mammography...
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PMID: 20601773
PDF is available here.
Abstract
We then modeled the effect of placing a "stimulating" electrode with a saline-like conductivity over F3, and a similar "reference" electrode over a right supraorbital (RS) location, as well as the complements of these locations, to compare expectations derived from the simulation with experimental d...
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PMID: 20350607
PDF is available here.
Abstract
Interfacial behaviour of the bone-cement interface has been studied under tensile, shear and mixed mode loading conditions. Bovine cancellous bone was used to bond with acrylic bone cement to form bone-cement interface samples, which were mechanically tested under selected tensile, shear and mixed m...
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PMID: 20416553
PDF is available here.
Abstract
We introduce an integrative three-dimensional electromechanical model of the left ventricle of the human heart. Electrical activity is represented by the ionic TP06 model for human cardiac cells, and mechanical activity is represented by the Niederer-Hunter-Smith active contractile tension model and...
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PMID: 20400690
PDF is available here.