Abstract
Global system of mobile communication (GSM) and other telecommunication technologies are now common place in Lagos state Nigeria. The introduction of GSM in 2002 considerably increased radiofrequency (RF) radiation exposure of the public from telecommunications transmitting and receiving antennae. Th...
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PMID: 21913539
PDF is available here.
Abstract
We investigated the abundance and distribution of nucleobases and nucleobase analogs in formic acid extracts of 12 different meteorites by liquid chromatography-mass spectrometry. The Murchison and Lonewolf Nunataks 94102 meteorites contained a diverse suite of nucleobases, which included three unus...
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PMID: 21836052
PDF is available here.
Abstract
We have identified these compounds and others in carbonaceous meteorites and/or as low temperature (laboratory) reaction products of pyruvic acid. In meteorites, we observe many as part of three newly reported classes of compounds: keto acids (pyruvic acid and homologs), hydroxy tricarboxylic acids...
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PMID: 21825143
PDF is available here.
Author(s) unavailable
Abstract
The paper gives the data characterizing the status of water supply systems, the efficiency of waterworks, and the quality of drinking and Severnaya Dvina River waters. It generalizes the data characterizing the sanitary-and-epidemiological situation and human health in the region. There is evidence f...
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PMID: 21842746
PDF is available here.
Abstract
Bioanalytical methods are used to quantitatively determine the concentration of drugs, biotransformation products or other specified substances in biological matrices and are often used to provide critical data to pharmacokinetic or bioequivalence studies in support of regulatory sub...
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PMID: 21827269
PDF is available here.
Author(s) unavailable
Abstract
Characterization of features of influenza pandemic development in Russia in relation to global process.
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PMID: 21809641
PDF is available here.
Abstract
Geisinger Health System's award-winning supply chain innovations have achieved an eye-popping $20 million in savings. And it's not stopping there.
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PMID: 21928576
PDF is available here.
Elizabeth R Remily-Wood,
Richard Z Liu,
Yun Xiang,
Yi Chen,
C Eric Thomas,
Neal Rajyaguru,
Laura M Kaufman,
Joana E Ochoa,
Lori Hazlehurst,
Javier Pinilla-Ibarz,
Jeffrey Lancet,
Guolin Zhang,
Eric Haura,
David Shibata,
Timothy Yeatman,
Keiran S M Smalley,
William S Dalton,
Emina Huang,
Ed Scott,
Gregory C Bloom,
Steven A Eschrich and
John M Koomen
Abstract
The Quantitative Assay Database (QuAD), http://proteome.moffitt.org/QUAD/, facilitates widespread implementation of quantitative mass spectrometry in cancer biology and clinical research through sharing of methods and reagents for monitoring protein expression and modification....
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PMID: 21656910
PDF is available here.
Abstract
We report the identification and validation of suitable reference genes in the bed bug, Cimex lectularius, by using qRT-PCR. The expression stability of eight reference genes in different tissues (abdominal cuticle, midgut, Malpighian tubules, and ovary) and developmental stages (early instar nymphs...
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PMID: 21845960
PDF is available here.
Abstract
We investigated the influences of mucormycosis on the hematologic, plasma biochemical, and other indicators of health in free-living platypuses across 18 Tasmanian river catchments. Live trapping enabled sampling of 161 (apparently) healthy and six ulcerated, mucormycosis-affected platypuses in 75 r...
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PMID: 21719813
PDF is available here.
Abstract
Being controlled release dosage forms, tablets allow an improved absorption and release profiles of Ofloxacin. The fact that drugs with fine particles size can be compressed well after wetting, so in our research studies Ofloxacin controlled release matrix tablets were prepared by wet granulation tec...
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PMID: 21715257
PDF is available here.
Abstract
We present an overview of the challenges and approaches to overcome them when performing quantitative bioanalysis of peptides and proteins by LC-MS/MS....
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PMID: 21679032
PDF is available here.
Abstract
We established reference ranges for the PEFR in children 4-18 years of age.
The Mini Wright Peak Flow Meter (MWPFM) and spirometry were used in this study. All tests were conducted using a standardized method recommended by the American Thoracic Society.
From a total...
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PMID: 21980829
PDF is available here.
Abstract
We review the concept of standardization and propose an exhaustive framework for the proper management of technology on pluripotent stem cells based on studies of global and regional initiatives. We demonstrated detailed observational analysis on global initiatives for the standardization of related...
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PMID: 21086070
PDF is available here.
Abstract
A high-performance liquid chromatographic method with triple-quadrupole mass spectrometry detection (LC-MS-MS) was developed and validated for the first time for the simultaneous quantification of zopiclone and its metabolites in rat plasma samples. The analytes were isolated from ra...
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PMID: 21547427
PDF is available here.
Abstract
Enterobacteriaceae producing ESBL and AmpC enzymes can be associated with failure of antibiotic therapy and related morbidity and mortality. Their routine detection in microbiology laboratories is still a problem. The aim of this study was to compare the sensitivity of selected phenotypic methods.
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PMID: 21525803
PDF is available here.
Abstract
This chapter describes the use of reversed-phase HPLC with multichannel coulometric electrochemical detection for the routine, sensitive, and simultaneous measurement of oxidized and reduced CoQ10 and CoQ9 in human plasma and serum. Analytes are first resolved chromatographically prior to electroche...
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PMID: 19082952
PDF is available here.
Abstract
Allergens are molecules with the capacity to elicit IgE responses in humans. When stimulated with allergens, most allergic patients respond with production of IgE specific for several proteins/allergens in the source material. The standardization of allergen extracts is essential in order to control...
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PMID: 18612605
PDF is available here.
Abstract
Selection and standardization of the work reference are the technical issues to be faced with in the bioassay of Chinese materia medica. Taking the bioassay of Coptis chinensis. as an example, the manufacture process of the famous-region drugs extraction was explained from the aspects of original ide...
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PMID: 21842660
PDF is available here.
Abstract
An investigation into activated partial thromboplastin time (APTT) in the plasma samples with varying Factor VIII activities has determined the following parameters of the quality of APTT-control reagent kits: coefficient of variation, linearity, sensitivity, and detection. The kit is shown to meet G...
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PMID: 21786611
PDF is available here.
Abstract
Our results suggested that miR-23a and miR-191 are the optimal reference microRNAs that can be used for normalization in profiling studies of cervical tissues; miR-23a is a novel microRNA normalizer....
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PMID: 21519184
PDF is available here.
Abstract
We present the development process for National Institute of Metrology (NIM) bovine serum albumin (BSA) certified reference material (CRM). Each CRM unit contains about 200 mg of purified BSA. The moisture, ignition residue, molecular weight, and high-performance liquid chromatography (HPLC) purity...
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PMID: 21509484
PDF is available here.
Mai X MX Luong,
Jonathan J Auerbach,
Jeremy M JM Crook,
Laurence L Daheron,
Derek D Hei,
Geoffrey G Lomax,
Jeanne F JF Loring,
Tenneille T Ludwig,
Thorsten M TM Schlaeger,
Kelly P KP Smith,
Glyn G Stacey,
Ren-He RH Xu and
Fanyi F Zeng
Abstract
Human embryonic and induced pluripotent stem cell lines are being generated at a rapid pace and now number in the thousands. We propose a standard nomenclature and suggest the use of a centralized database for all cell line names and a minimum set of information for reporting new derivations.
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PMID: 21474098
PDF is available here.
Abstract
We investigated the accumulation of the corresponding transcripts to those of two other stilbene biosynthesis related genes phenylalanine ammonia lyase (PAL) and stilbene synthase (STS) in response to pathogen infection. Using three computer-based statistical methods and C (t) values or LRE method g...
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PMID: 21340517
PDF is available here.
Abstract
Glycated haemoglobin has been in use to monitor control of blood glucose in diabetic patients for about three decades. It provides an average blood glucose level during preceding 10-12 weeks. It is a very convenient blood test, can be done in any clinical setting regardless of prandi...
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PMID: 21465979
PDF is available here.
Abstract
A simple and rapid HPLC method with UV detection was developed for the separation of ciprofloxacin, levofloxacin and moxifloxacin. Chromatography was carried out using a BDS Hypersil C18 (100 x 4.6 mm, 2.4 microm) HPLC column and an isocratic mobile phase consisting of MeOH/25 mM pho...
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PMID: 21612150
PDF is available here.
Abstract
A quality control material (QCM) is a necessity in hair drug analysis, but it is not always easy to have an authentic hair sample containing various target drugs and metabolites. In the present study, the feasibility of rat hair as a QCM was examined for its application in the determination of metham...
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PMID: 21544724
PDF is available here.
Abstract
Based on the original recommendation of the Expert Panel on the Theory of Reference Values of the International Federation of Clinical Chemistry and Laboratory Medicine (IFCC-LM), updated guidelines were recently published under the auspices of the IFCC-LM and the Clinical and Laboratory Standards In...
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PMID: 21464019
PDF is available here.
Abstract
To develop an HPLC method for determination of gallic acid, hydroxysafflor yellow A, cinnamic aldehyde and piperine in Tibetan medicine Dangzuo, and to compare the content of four active components in Dangzuo of different Tibetan regions.
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PMID: 21809583
PDF is available here.
Abstract
Superabsorbent polyacrylate (SAP) is an important industrial chemical manufactured primarily as sodium polyacrylate but occasionally as potassium salt. It has many applications owing to its intrinsic physical property of very high water absorption, which can be more than 100 times it...
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PMID: 21416441
PDF is available here.
Abstract
Among the most important functions of a pathology or laboratory medicine service is the clear, accurate, and rapid communication of critical test results (critical values) to patient care providers. Pathologists and laboratory professionals are often confronted with many obstacles in the reporting of...
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PMID: 21411773
PDF is available here.
Helen M HM Moore,
Andrea B AB Kelly,
Scott D SD Jewell,
Lisa M LM McShane,
Douglas P DP Clark,
Renata R Greenspan,
Daniel F DF Hayes,
Pierre P Hainaut,
Paula P Kim,
Elizabeth A EA Mansfield,
Olga O Potapova,
Peter P Riegman,
Yaffa Y Rubinstein,
Edward E Seijo,
Stella S Somiari,
Peter P Watson,
Heinz-Ulrich HU Weier,
Claire C Zhu and
Jim J Vaught
Abstract
Human biospecimens are subjected to collection, processing, and storage that can significantly alter their molecular composition and consistency. These biospecimen preanalytical factors, in turn, influence experimental outcomes and the ability to reproduce scientific results. Currently, the extent an...
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PMID: 21433001
PDF is available here.
Abstract
Abstract The recent campaign for standardization of creatinine measurements has been promoted to allow the widespread use of formulas for estimating the glomerular filtration rate (GFR). However, studies on trueness verification and measurement interferences still show disappointing...
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PMID: 21428858
PDF is available here.
Abstract
Our data show that hydration water plays an essential role for enhancing molecular dynamics of residues in tails and interhelical loops, while it is found less important for residues in transmembrane domains or rigid, structured loop segments. In contrast, switching the lipids from the gel to their...
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PMID: 21401038
PDF is available here.
Abstract
We report a 97% complete resonance assignment of the backbone and side-chain (13)C atoms....
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PMID: 21401039
PDF is available here.
Abstract
We report here the identification and complete characterization of a novel oxysterol, 3β,5α-dihydroxycholest-7-en-6-one (DHCEO), as a biomarker for 7-DHC oxidation in fibroblasts from SLOS patients and brain tissue from a SLOS mouse model. Deuterated (d(7))-standards of 7-DHC and DHCEO were synthe...
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PMID: 21402677
PDF is available here.
Abstract
The correlation and bias of four commercial reagent kits for serum total protein were found to be acceptable. Thus, these reagent kits can be used reliably in China....
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PMID: 21391866
PDF is available here.
Abstract
4-Methylimidazole (4MeI) is a nitrogen compound formed during the manufacture of class III and IV caramel colors. The European Commission has limited its content to 250 ppm. Two methods were compared to perform 4MeI quantification in caramels. The first one, currently used and considered to be the re...
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PMID: 21381772
PDF is available here.
Abstract
We report on magic-angle-spinning solid-state NMR studies of the amyloid-like aggregates of an htt N-terminal fragment. We find that the polyQ portion of this peptide exists in a rigid, dehydrated amyloid core that is structurally similar to simpler polyQ fibrils and may contain antiparallel β-shee...
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PMID: 21381744
PDF is available here.
Chen-Hua CH Liu,
Cheng-Chao CC Liang,
Kai-Wen KW Huang,
Chun-Jen CJ Liu,
Shih-I SI Chen,
Jou-Wei JW Lin,
Peir-Haur PH Hung,
Hung-Bin HB Tsai,
Ming-Yang MY Lai,
Pei-Jer PJ Chen,
Jun-Herng JH Chen,
Ding-Shinn DS Chen and
Jia-Horng JH Kao
Abstract
Summary Background and objectives Although percutaneous liver biopsy (PLB) is the gold standard for staging hepatic fibrosis in hemodialysis patients with chronic hepatitis C (CHC) before renal transplantation or antiviral therapy, concerns exist about serious postbiopsy complication...
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PMID: 21393486
PDF is available here.
Abstract
Our hypothesis was that any lignin, regardless of its botanical origin, could be used to construct a standard curve for the purpose of determining lignin concentration in a variety of plants. To test our hypothesis, lignins were isolated from a range of diverse plants and, along with three commercia...
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PMID: 21375240
PDF is available here.
Abstract
We developed a sensitive, quantitative, and highly specific sandwich ELISA to measure apoCIII in both nonhuman primate and human serum. Our assay generates a linear calibration curve from 0.01 μg/ml to 10 μg/ml using an apoCIII standard that was purified from cynomolgus monkey serum. It is highly...
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PMID: 21371998
PDF is available here.
Abstract
We also review medications commonly used for pediatric sedation and pain management and discuss resources available to physicians who provide pediatric sedation....
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PMID: 21485927
PDF is available here.
Abstract
Three IgG class anti-bovine CXCL8 (bCXCL8) monoclonal antibody (mAb)-secreting hybridomas, SH8-8D7, SH8-12A5 and SH8-2A1, were developed. SH8-8D7 was IgG2a, and SH8-12A5 and SH8-2A1 were IgG1. All three mAbs detected recombinant bCXCL8 (rbCXCL8) by immunoprecipitation and Western blotting. SH8-2A1 co...
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PMID: 21436015
PDF is available here.
Abstract
Our aim was to evaluate the influence of both calibrators on GH results....
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PMID: 21361855
PDF is available here.
Abstract
A new gold standard data set for validation of 2D/3D registration based on a porcine cadaver head with attached fiducial markers was presented in the first part of this article. The advantage of this new phantom is the large amount of soft tissue, which simulates realistic conditions for registration...
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PMID: 21520861
PDF is available here.
Abstract
A new frequency-domain estimation algorithm has been developed that uses a priori information to simultaneously improve imaging quality and time resolution in photoacoustic tomography with incomplete data sets.
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PMID: 21520862
PDF is available here.
Abstract
We hypothesised that autoantibodies against HER2 might have a stimulatory capacity and could be the cause of the HER2 gene amplification phenomenon. To investigate this, we developed a test for the detection of autoantibodies against HER2 in serum (S-HER2Ab)....
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PMID: 21320029
PDF is available here.
Abstract
Stocks of 95/560, the 1st International Standard for sex hormone-binding globulin (SHBG), are running out, and 08/266 has been prepared as a replacement. We compared the steroid binding capacities of 95/560 and 08/266.
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PMID: 21345159
PDF is available here.
Abstract
The haemopexin fold is present in almost all life forms and is utilized for carrying out diverse physiological functions. The structure of CP4, a haemopexin-fold protein from cow pea (Vigna unguiculata), was determined at 2.1 Å resolution. The protein exists as a monomer both in solution and in t...
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PMID: 21301085
PDF is available here.