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Fatty Acids (17):
Recent article
Fatty Acids
Abstract
We investigated the roles of Elovl6 in foam cell formation in macrophages and atherosclerosis in mice.
To investigate the roles of Elovl6 in macrophages in the progression of atherosclerosis, we transplanted bone marrow cells of wild-type or Elovl6(-/-) mice into irradiated LDL-R(-/-...
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PMID: 21817094
PDF is available here.
PDF is available here.
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Abstract
We demonstrate that a functional reversal of the β-oxidation cycle can be used as a metabolic platform for the synthesis of alcohols and carboxylic acids with various chain lengths and functionalities. This pathway operates with coenzyme A (CoA) thioester intermediates and directly uses acetyl-CoA...
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PMID: 21832992
PDF is available here.
PDF is available here.
Abstract
The aim of the present study is to examine the effects of dietary saturated fatty acids on liver adiponectin receptor 1 (AdipoR1) and adiponectin receptor 2 (AdipoR2) in ethanol-administered animals and in ethanol-exposed cultured hepatic cells, and to explore the underlying molecula...
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PMID: 21194380
PDF is available here.
PDF is available here.
Abstract
Erythrocyte phospholipids and lipid fatty acid composition was investigated at different stages of exposure to high-caloric diet in male Wistar rats. The revealed modification of erythrocyte lipids shows specific features of membrane response to stress factors of alimentary nature, i...
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PMID: 21961296
PDF is available here.
PDF is available here.
Abstract
We examined the interrelationships among AMPK, ACC2, and fatty acid oxidation under 12 controlled conditions in isolated muscle. Incubation of soleus muscle (0-12 h) did not alter fatty acid oxidation, but did increase AMPK and ACC2 phosphorylation (24%-30%). Muscle incubation with palmitate (2 mmo...
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PMID: 21574785
PDF is available here.
PDF is available here.
Abstract
We hypothesized that diets rich in MCFA result in a lower ectopic lipid accumulation and insulin resistance compared to diets rich in LCFA. Feeding mice high-fat (HF) (45% kcal fat) diets for 8 weeks rich in triacylglycerols composed of MCFA (HFMCT) or LCFA (HFLCT) revealed a lower body weight gain...
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PMID: 20655716
PDF is available here.
PDF is available here.
PLoS Biology (9)3 2011
Abstract
We report on NHR-80/HNF4, a nuclear receptor that specifically mediates longevity induced by depletion of the germ line through a mechanism that implicates fatty acid monodesaturation.
nhr-80/HNF4 is induced in animals lacking a germ line and is specifically required for their extend...
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PMID: 21423649
PDF is available here.
PDF is available here.
Abstract
We investigated whether alterations in cardiac energy metabolism contribute to the cardioprotective effects induced by CR. Hearts from control or short-term CR mice were subjected to ex vivo I/R and metabolism, as well as post-ischemic functional recovery was measured. Even in the presence of elevat...
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PMID: 21140129
PDF is available here.
PDF is available here.
Abstract
We characterize how the O. carboxidovorans proteome adapts to different lifestyles of chemolithoautotrophy and heterotrophy. Fatty acid methyl ester (FAME) analysis of O. carboxidovorans grown with acetate or with syngas showed that the bacterium changes membrane fatty acid composition. Quantitative...
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PMID: 21386900
PDF is available here.
PDF is available here.
Abstract
Our results show that human serum extracts enriched with endogenous long-chain hydroxy fatty acids possess anti-inflammatory and anti-proliferative activity. These findings support a hypothesis that the reduction of these metabolites with age may result in a compromised ability to defend against unc...
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PMID: 21586136
PDF is available here.
PDF is available here.
Abstract
We also present methods for the determination of compositions of constituent fatty acids, distribution of fatty acids between sn-1 and sn-2 positions, and determination of contents of individual lipid classes by gas-liquid chromatography. These methods are applicable to isolated chloroplasts or some...
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PMID: 20960124
PDF is available here.
PDF is available here.
British Journal of Nutrition (105)2 2011
Abstract
The mode of action of highly unsaturated fatty acids (HUFA) in regulating gilthead sea bream (Sparus aurata) head kidney (HK) cortisol production was studied through in vitro trials using a dynamic superfusion system. Fish were previously fed with different diets containing several inclusion levels...
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PMID: 20836902
PDF is available here.
PDF is available here.
British Journal of Nutrition (105)1 2011
Abstract
We suggest that the proteome changes in Longissimus muscle contributed to greater intramuscular lipid content in CLA-supplemented pigs....
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PMID: 20807461
PDF is available here.
PDF is available here.
Abstract
We investigated the effects of withholding feed for the first 48 h PH (delayed feeding, DF) on lipogenic gene expression through 8 days PH. Body weight gain was significantly depressed by DF. Plasma levels of the major metabolic hormones that regulate lipogenic gene expression (insulin, glucagon and...
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PMID: 20817117
PDF is available here.
PDF is available here.
Abstract
We examined the influence of the reproductive cycle and environmental variables on the gonadal fatty acid profile in the tropical scallop Nodipecten nodosus. Individuals from a natural population in north-eastern Venezuela (Caribbean Sea) were sampled monthly during one year. The gonadosomatic index...
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PMID: 20828631
PDF is available here.
PDF is available here.
Critical Care Medicine (38)12 2010
Abstract
Endotoxin triggers a reorganization of the energy metabolic pathway, including the promotion of fatty acid utilization to adapt to a high energy demand during endotoxemia. However, the factors responsible for the metabolic adaptation and characteristic pathologies resulting from defective utilizatio...
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PMID: 20838331
PDF is available here.
PDF is available here.
British Journal of Nutrition (104)12 2010
Abstract
High-fat or high-fat-high-sucrose diets are known to induce non-alcoholic fatty liver disease and this is emerging as one of the most common liver diseases worldwide. Some polyphenols have been reported to decrease rat hepatic lipid accumulation, in particular those extracted from red grapes such as...
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PMID: 20673376
PDF is available here.
PDF is available here.
British Journal of Nutrition (104)12 2010
Abstract
Dietary fish oil modulates skeletal muscle membrane fatty acid composition. Similar changes in heart membrane composition modulate myocardial oxygen consumption and enhance mechanical performance. The rat in vivo autologous perfused hindlimb was used to investigate the influence of membrane composit...
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PMID: 20691135
PDF is available here.
PDF is available here.
British Journal of Nutrition (104)11 2010
Abstract
These results suggest that long-term consumption of CHO-enriched diets may be associated with a sustained pro-inflammatory state....
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PMID: 20691129
PDF is available here.
PDF is available here.
British Journal of Nutrition (104)11 2010
Abstract
We investigated selective and non-selective savannah, savannah/aquatic and aquatic hunter-gatherer/scavenger foraging strategies. We found (range of medians in en%) intakes of moderate-to-high protein (25-29), moderate-to-high fat (30-39) and moderate carbohydrates (39-40). The fatty acid compositio...
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PMID: 20860883
PDF is available here.
PDF is available here.
Abstract
We first studied homologous genes to OAF1 and PIP2 of Saccharomyces cerevisiae, but their disruption did not change growth on oleic acid at all. We next characterized a Y. lipolytica gene, POR1 (primary oleate regulator 1), an ortholog of farA encoding a transcriptional activator that regulates fatt...
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PMID: 20977884
PDF is available here.
PDF is available here.
Abstract
We report the physico-chemical characterisation of fatty acid stabilised aqueous magnetic fluids, which are ideal systems for studying the influence of nanoparticle aggregation on the emergent magnetic resonance properties of the suspensions. Stable colloids of superparamagnetic magnetite, Fe(3)O(4)...
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PMID: 20922236
PDF is available here.
PDF is available here.
Acta Pharmacologica Sinica (31)11 2010
Abstract
To test whether pharmacological inhibition of Diacylglycerol acyltransferase 1 (DGAT1) by a small-molecule inhibitor H128 can improve metabolism disorders in leptin receptor-deficient db/db mice.
To investigate the effect of H128 on intestinal fat absorption,db/db mic...
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PMID: 21052084
PDF is available here.
PDF is available here.
Abstract
To date, studies on volatile metabolites in cereal grain have focused mainly on a single species. In this paper, results are presented of the analysis of volatile compounds in five cereal grain species (spring wheat, durum wheat, triticale, rye, oats and barley) based on representative sampling of a...
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PMID: 20730644
PDF is available here.
PDF is available here.
Abstract
To review the evidence implying a role of inflammatory signaling pathways, specifically nuclear factor-κB and c-Jun NH2-terminal kinase, in fatty acid-induced skeletal muscle insulin resistance and to discuss the potential of dietary interventions to interfere with these processes.
Fatty acids can...
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PMID: 20842028
PDF is available here.
PDF is available here.
British Journal of Nutrition (104)9 2010
Abstract
We investigated the impact of four diets distinct in fat quantity and quality on 8-iso-PGF2α (a major F2-isoprostane and oxidative stress indicator), 15-keto-13,14-dihydro-PGF2α (15-keto-dihydro-PGF2α, a major PGF2α metabolite and marker of cyclooxygenase-mediated inflammation) and C-reactive pr...
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PMID: 20569506
PDF is available here.
PDF is available here.
Health Physics (99)5 2010
Abstract
The biokinetics of radiocarbon (¹⁴C) in rats continuously ingested in the forms of amino acids (glycine and leucine) or as foods (wheat and rapeseed) were examined and compared with each other. The differences in the biokinetics between ¹⁴C-amino acids and ¹⁴C-foods were observed in the exc...
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PMID: 20938237
PDF is available here.
PDF is available here.
Journal of Insect Physiology (56)11 2010
Abstract
We demonstrated that sex pheromone production in mated female Heliothis virescens moths is dependent upon hemolymph trehalose concentration (HTC), which is influenced by activities such as the feeding of adults on sucrose. In this paper we demonstrate, for the first time, that this effect also occur...
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PMID: 20540946
PDF is available here.
PDF is available here.
Abstract
We report that catalytic quantities of the Lewis acidic metal catalysts scandium triflate and bismuth triflate promote conversion of oleic, linoleic, palmitic and myristic acids and their glyceryl triesters to the corresponding methyl esters (biodiesel) in greater than 90% yield upon microwave heati...
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PMID: 20714659
PDF is available here.
PDF is available here.
Abstract
We determined the precise substrate specificities of all the ELOVLs by in vitro analyses. Particularly notable was the high activity exhibited by ELOVL1 toward saturated and monounsaturated C20- and C22-CoAs, and that it was essential for the production of C24 sphingolipids, which are unique in thei...
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PMID: 20937905
PDF is available here.
PDF is available here.
Journal of Biological Chemistry (285)43 2010
Abstract
The intracellular fatty acid-binding proteins (FABPs) are abundantly expressed in almost all tissues. They exhibit high affinity binding of a single long-chain fatty acid, with the exception of liver FABP, which binds two fatty acids or other hydrophobic molecules. FABPs have highly similar tertiary...
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PMID: 20716527
PDF is available here.
PDF is available here.
Acta Pharmacologica Sinica (31)10 2010
Abstract
Insulin plays an important role in the stimulation of vascular nitric oxide production, with both short term (vasomotility and anti-thrombotic effects) and long term (smooth muscle cell growth and migration inhibition) benefits. Impaired vasodilatory response to insulin, the hallmark...
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PMID: 20802503
PDF is available here.
PDF is available here.
Abstract
Some nutritional components of the edible seaweeds Cryptonemia obovata and Rhodymenia corallina were determined. The amino acid content ranged from 1.0 +/- 0.3 to 4174.2 +/- 14.2 mg 100 g(-1) dry wt in C. obovata and between 0.9 +/- 0.3 and 2657.0 +/- 13.5 mg 100 g(-1) dry wt in R. corallina. The mo...
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PMID: 21121265
PDF is available here.
PDF is available here.
Abstract
We conducted a dietary intervention trial to study these effects in participants at risk of developing metabolic syndrome.
We conducted a 5-center, parallel design, randomized controlled trial [RISCK (Reading, Imperial, Surrey, Cambridge, and Kings)]. The primary and secondary outcomes were changes...
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PMID: 20739418
PDF is available here.
PDF is available here.
Abstract
We consider substrate-related compounds, intermediates or products of the Luc catalyzed reactions, in addition to anesthetics and, fatty acids. This review summarizes the main inhibitors of Luc and the corresponding inhibition kinetic parameters.
Copyright 2010 Elsevier B.V. All rights reserved....
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PMID: 20655239
PDF is available here.
PDF is available here.
Abstract
Gas liquid chromatography was used to analyze the composition of plasma free fatty acids (FA) and erythrocyte lipid FAs in patients with metabolic syndrome (MS) in various glucose-insulin homeostasis. The serum lipids of oxylipins were studied in patients with MS, by applying enzyme immunoassay. The...
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PMID: 21162180
PDF is available here.
PDF is available here.
Abstract
Evidence presented over the past 20 years has shown that long-chain polyunsaturated fatty acids (LCPUFAs), especially the n-3 fatty acids such as eicospentaenoic acid (EPA) and docosahexaenoic acid (DHA) are beneficial for bone health. Some studies in humans indicate that LCPUFAs can increase bone f...
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PMID: 20600307
PDF is available here.
PDF is available here.
Abstract
Waste Management (30)10 2010
Abstract
Inocula derived from an anaerobic digester were used to study (i) their potential for methane production and (ii) the utilisation rates of different short chain fatty acids (SCFAs) by the microbial community in defined media with mono-carbon sources (formic-, acetetic-, propionic-, butyric acid) in...
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PMID: 20558054
PDF is available here.
PDF is available here.
Bioresource Technology (101)19 2010
Abstract
Structured lipids (SLs) having long-chain fatty acids at sn-2 and medium-chain caprylic acid (CA, 8:0) at their sn-1,3-positions from corn oil (CO) were obtained and optimized by response surface methodology (RSM) with a three-level, three-factor face-centered cube design. Compositio...
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PMID: 20576567
PDF is available here.
PDF is available here.
Abstract
I (ID03-0561(T)) showed low relatedness to the other strains studied. The three strains in group II (ID03-0784(T), ID03-0808 and ID03-0809) formed a group with high relatedness (98-100 %) and showed low relatedness to the other strains studied. The two strains in group III (ID03-0810(T) and ID03-0...
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PMID: 19933586
PDF is available here.
PDF is available here.
Abstract
A Gram-negative, motile, non-spore-forming bacterial strain, designated MJ07(T), was isolated from a farm soil and was characterized to determine its taxonomic position by using a polyphasic approach. Comparative 16S rRNA gene sequence analysis showed that strain MJ07(T) belongs to the family Alcali...
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PMID: 19933592
PDF is available here.
PDF is available here.
Abstract
We propose the names Mucilaginibacter gossypii sp. nov. (type strain Gh-67(T) =NCIMB 14470(T) =KCTC 22380(T)) and Mucilaginibacter gossypiicola sp. nov. (type strain Gh-48(T) =NCIMB 14471(T) =KCTC 22379(T))....
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PMID: 19946048
PDF is available here.
PDF is available here.
Abstract
I and/or anteiso-C₁₇ :₁ B), iso-C₁₅:₀ and C₁₆:₁ω5c. The fatty acid content of strain 6424S-61(T) mainly comprised iso-C₁₅ :₁ G and iso-C₁₅:₀. Comparative analysis of phenotypic and phylogenetic traits indicated that strains 6424S-25(T) and 6515J-31(T) represented t...
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PMID: 19946049
PDF is available here.
PDF is available here.
Abstract
Two strains of anaerobic, Gram-stain-negative bacilli isolated from the human oral cavity (D033B-12-2(T) and D080A-01) were subjected to a comprehensive range of phenotypic and genotypic tests and were found to be distinct from any previously described species. 16S rRNA gene sequence analysis reveal...
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PMID: 19946051
PDF is available here.
PDF is available here.
Abstract
These results and the differentiating biochemical and chemotaxonomic properties show that strain R4-1A(T) represents a novel species, for which the name Chryseobacterium culicis sp. nov. is proposed. The type strain is R4-1A(T) (=LMG 25442(T) =CCM 7716(T))....
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PMID: 19933582
PDF is available here.
PDF is available here.
Abstract
A marine bacterial strain, designated fav-2-10-05(T), was isolated from the mucus layer of a coral of the genus Favia, collected from the coral reef in the Gulf of Eilat, Israel (29.5 ° N 34.9 ° E). On the basis of 16S rRNA gene sequence comparisons, strain fav-2-10-05(T) was affiliated with t...
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PMID: 19915103
PDF is available here.
PDF is available here.
Abstract
A polyphasic taxonomic study of a halotolerant bacterium, isolated from sandy rhizospheric soil in Sarbandar, Persian Gulf, Iran, revealed that strain HM6(T) represents a novel species within the genus Nocardiopsis. Results of the 16S rRNA gene sequence comparison revealed that strain HM6(T) cluster...
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PMID: 19933587
PDF is available here.
PDF is available here.
Abstract
Three strains of Gram-negative, rod-shaped, non-spore-forming bacteria (M 2040(T), M 1973 and M 1878-SK2), isolated from milk of camels at a camel-milk production farm in the United Arab Emirates, were investigated for their taxonomic allocation. On the basis of 16S rRNA gene sequence similarities,...
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PMID: 19933583
PDF is available here.
PDF is available here.
Abstract
A Gram-positive, endospore-forming, rod-shaped bacterium, strain PD-A10(T), was isolated from salted crab (poo-khem) in Thailand and subjected to a taxonomic study. Phenotypic and chemotaxonomic characteristics, including phylogenetic analyses, showed that the novel strain was a member of the genus...
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PMID: 19933584
PDF is available here.
PDF is available here.
Abstract
A bacterial strain, SPC26(T), was isolated from a sediment sample of the Southern Ocean off Antarctica. The strain was Gram-staining- and catalase-positive and contained lysine and alanine in the cell-wall peptidoglycan. The major cellular fatty acids were anteiso-C₁₅:₀ (54.92 %), iso-C₁...
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PMID: 19783612
PDF is available here.
PDF is available here.
Abstract
These results suggested that strain VN05A0561(T) represents a novel species of the genus Pseudonocardia, for which the name Pseudonocardia babensis sp. nov. is proposed. The type strain is VN05A0561(T) (=VTCC-A-1757(T)=NBRC 105793(T))....
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PMID: 19933589
PDF is available here.
PDF is available here.
Abstract
A Gram-stain-positive, aerobic bacterium, designated strain BZ41(T), was isolated from hydrocarbon-contaminated soil. Phylogenetic analysis based on 16S rRNA gene sequences showed that strain BZ41(T) was related to members of the genus Agromyces and showed highest similarity with the type strain of...
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PMID: 19933590
PDF is available here.
PDF is available here.
Abstract
A novel Gram-negative, rod-shaped, non-motile bacterium, designated strain LW7(T), was isolated from a water sample collected at a depth of 4.5 m from Lonar Lake in Buldhana district, Maharastra, India. The cell suspension was dark-reddish orange due to the presence of carotenoids. The fatty acids w...
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PMID: 19933591
PDF is available here.
PDF is available here.
Abstract
A xylanolytic bacterium, strain S1-3(T), was isolated from soil collected in Nan province, Thailand. It was characterized taxonomically based on phenotypic characteristics and 16S rRNA gene sequence comparison. The strain was a Gram-stain-positive, facultatively anaerobic, spore-forming, rod-shaped...
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PMID: 19915111
PDF is available here.
PDF is available here.
Abstract
A Gram-staining-negative, yellow-coloured, strictly aerobic, non-spore-forming, rod-shaped bacterium, designated HS39(T), isolated from a soil sample collected from a natural Populus euphratica forest in Xinjiang, China, was characterized using a polyphasic approach. The isolate grew optimally at 30...
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PMID: 19933581
PDF is available here.
PDF is available here.
Abstract
A Gram-negative, rod-shaped, non-spore-forming, strictly aerobic strain with gliding motility, designated JAMB N27(T), was isolated from sediment adjacent to sperm whale carcasses off Kagoshima, Japan, at a depth of 219 m. Strain JAMB N27(T) contained MK-6 as the major isoprenoid quinone and iso-C...
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PMID: 19915102
PDF is available here.
PDF is available here.
Abstract
Phenotypic and phylogenetic studies were performed on three strains of an acetogenic bacterium isolated from livestock-impacted soil. The bacterium stained Gram-negative and was a non-spore-forming rod that was motile by peritrichous flagella. The novel strains had an optimum pH for growth of 8.0-8....
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PMID: 19965999
PDF is available here.
PDF is available here.
Abstract
A short coccoid- to rod-shaped, motile, mesophilic actinobacterium, strain MSL-22(T), was isolated from soil on Bigeum Island, Korea. A polyphasic study was undertaken to establish the taxonomic position of this strain. Phylogenetic analysis based on 16S rRNA gene sequences revealed that strain MSL-...
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PMID: 19915109
PDF is available here.
PDF is available here.