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Welcome to the Pubget Medical Subject Headings (MESH) browser. Click on a topic or subtopic below to explore related papers. In the gold box is the most recent paper about the current MESH term, and below are 20 related papers.
Lipoproteins (8):
Recent article
Lipoproteins
Abstract
To test whether obese children with non-alcoholic fatty liver disease have impaired vascular function compared with obese children with normal liver fat content.
Obese children (n = 28, 16 males, mean age 10.9 ± 0.7 years, body mass index [BMI] 31.9 ± 4.5 kg/m(2)) w...
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PMID: 20950125
PDF is available here.
PDF is available here.
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Rejuvenation Research (14)2 2011
Abstract
The aim of this study was to investigate the relationship among apolipoprotein E (APOE) polymorphism, body mass index (BMI), and dyslipidemia and how these factors modify overall mortality in a cohort of hospitalized elderly patients.
Plasma concentrations of total ch...
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PMID: 21595502
PDF is available here.
PDF is available here.
Abstract
We show that the biochemical pathways associated with tumour cell chemosensitivity to platinum-based drugs are highly coincident, i.e. they describe a consensus phenotype. Direct integration of metabolome and transcriptome data at the point of pathway analysis improved the detection of consensus pat...
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PMID: 21483477
PDF is available here.
PDF is available here.
Journal of Proteomics (74)2 2011
Abstract
Lipid rafts are microdomains of the phospholipid bilayer, proposed to form semi-stable "islands" that act as a platform for several important cellular processes; major classes of raft-resident proteins include signalling proteins and glycosylphosphatidylinositol (GPI)-anchored protei...
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PMID: 21070894
PDF is available here.
PDF is available here.
Abstract
We evaluated the potential of Brucella abortus 19 kDa outer membrane protein (U-Omp19) as an edible subunit vaccine against brucellosis. We investigated the protective immune response elicited against oral B. abortus infection after vaccination of mice with leaves from transgenic plants expressing U...
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PMID: 21264260
PDF is available here.
PDF is available here.
Abstract
We showed by DNA microarray that CmeR, a transcriptional regulator repressing the expression of the multidrug efflux pump CmeABC, modulates the expression of a three-gene operon (cj0089, cj0090, and cj0091) encoding a cluster of lipoproteins in C. jejuni.
In this work, we characteriz...
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PMID: 21625391
PDF is available here.
PDF is available here.
Abstract
These results demonstrated that mucosal immunization with chitosan-psaA may successfully generate mucosal and systemic immune responses and prevent pneumococcal nasopharyngeal colonization. Hence, a chitosan-DNA nanoparticle vaccine expressing pneumococcal major immunodominant antigens after intrana...
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PMID: 21047997
PDF is available here.
PDF is available here.
Abstract
We observed that inhibition of Sp1 DNA-binding by mithramycin A diminished ABCA1 expression and ApoAI-mediated cholesterol efflux induced by ApoB-carrying lipoproteins, and that mutation of the Sp1-binding motif in the ABCA1 promoter region diminished ApoB-carrying lipoprotein-induced ABCA1 promoter...
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PMID: 21779326
PDF is available here.
PDF is available here.
Biochimica et Biophysica Acta (1811)1 2011
Abstract
We have characterized the effect of lipid composition of the membrane vesicles on the function of purified HpPAF-AH. Lipid composition of the vesicles was varied by incorporating varying amounts of cholesterol in the matrix phospholipids, POPC and DPPC, and its effect on the membrane binding, membra...
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PMID: 20869463
PDF is available here.
PDF is available here.
EMBO Journal (29)24 2010
Structural basis for docking of peroxisomal membrane protein carrier Pex19p onto its receptor Pex3p.
Abstract
We present the three-dimensional structure of the complex between a cytosolic domain of Pex3p and the binding-region peptide of Pex19p. The overall shape of Pex3p is a prolate spheroid with a novel fold, the 'twisted six-helix bundle.' The Pex19p-binding site is at an apex of the Pex3p spheroid. A 1...
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PMID: 21102411
PDF is available here.
PDF is available here.
Nature Medicine (16)12 2010
Abstract
We report that in wild-type mice, excitation with a wavelength of ∼730 nm identified retinosomes in the retinal pigment epithelium, and excitation with a wavelength of ∼910 nm revealed at least one additional retinal fluorophore. The latter fluorescence was absent in eyes of genetically modified...
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PMID: 21076393
PDF is available here.
PDF is available here.
Epidemiology and Infection (138)12 2010
Abstract
We enrolled adults undergoing chest radiography at three Indian Health Service clinics in the Southwestern United States and collected acute and convalescent serum for measurement of PsaA and PspA titres and urine for pneumococcal antigen detection. Blood and sputum cultures were obtained at the dis...
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PMID: 20334727
PDF is available here.
PDF is available here.
Abstract
We used the sphingomyelin (SM) synthase 2 (Sms2) gene knockout (KO) approach to test our hypothesis that selectively decreasing plasma lipoprotein SM can play an important role in preventing atherosclerosis.
The sphingolipid de novo synthesis pathway is considered a promising target for pharmacologi...
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PMID: 20814016
PDF is available here.
PDF is available here.
Abstract
We isolated several new LolCDE mutants that cause outer membrane localization of lipoproteins possessing LolCDE-avoidance signals. Mutations were found in all three subunits of LolCDE, including the cytoplasmic ATPase subunit LolD. However, the extent of outer membrane sorting of inner membrane-spec...
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PMID: 20888319
PDF is available here.
PDF is available here.
Abstract
Extracellular DNA (eDNA) is a structural component of the polymeric matrix of biofilms from different species. Different mechanisms for DNA release have been proposed including lysis of cells, lysis of DNA-containing vesicles, and DNA secretion. Here, a genome-wide screen of 3985 non-lethal mutation...
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PMID: 20833130
PDF is available here.
PDF is available here.
New Microbiologica (33)4 2010
Abstract
Major progress has been made in the basic research of leptospirosis a global zoonotic disease. Recent knowledge on the genome of L. interrogans and the emergence of new genetic tools for comparative genetic studies have further developed research into the genetic pathogenesis of this illness. Many o...
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PMID: 21213586
PDF is available here.
PDF is available here.
Abstract
Out of the 6 expected genotypes, only 5 were detected in participants: E3/3 (56.0%), E3/4 (23.6%), E4/4 (8.2%), E2/4 (3.3%), E2/3 (8.9%). The ε3 allele (72%) was the most frequent, followed by ε4 (22%) and ε2 (6%). No difference was found in plasma levels of either apoE or in apoE genotype freque...
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PMID: 20455863
PDF is available here.
PDF is available here.
Abstract
Outer membrane proteins of Pasteurella (P.) multocida have been known to be protective immunogens. Pasteurella lipoprotein E (PlpE) has been reported to be an important cross reactive outer membrane protein in P. multocida. The gene encoding the PlpE of P. multocida serotypes A: 3, B: 2 and D: 1 was...
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PMID: 20706030
PDF is available here.
PDF is available here.
Thrombosis and Haemostasis (104)3 2010
Abstract
Our data indicate that coagulation acceleration can be attributed neither to platelet activation and nor to activation of a clotting factor. When TFPI (tissue factor pathway inhibitor) was absent, no effect on lag time was observed and the anticoagulant activity of TFPI was decreased in the presence...
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PMID: 20589323
PDF is available here.
PDF is available here.
Vnitrni lekarstvi (56)9 Suppl 2010
Abstract
New examination approaches in biochemical analysis of lipoproteins can identify and quantify atherogenic plasma lipoproteins, including small dense LDL and characterise a lipoprotein spectrum as a non-atherogenic lipoprotein profile phenotype A, respectively as an atherogenic lipoprotein profile phe...
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PMID: 21137169
PDF is available here.
PDF is available here.
Atherosclerosis (212)1 2010
Abstract
Atherosclerosis (212)1 2010
Abstract
These results demonstrate that exenatide acutely and profoundly inhibits postprandial excursions of proatherogenic lipids and lipoproteins and may offer additional cardiovascular risk reduction (NCT00974272).
Published by Elsevier Ireland Ltd....
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PMID: 20557887
PDF is available here.
PDF is available here.
Atherosclerosis (212)1 2010
Abstract
We performed a systematic review and meta-regression analyses of randomized controlled trials of lipid-modifying treatments selected from a PubMed search on literature published from 1966 to 2008.
We identified 64 randomized controlled trials (active groups, n=96,807; control groups, n=98,681) that...
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PMID: 20457452
PDF is available here.
PDF is available here.
Abstract
These results suggest that postmenopausal women who present with metabolic syndrome had increased fat-rich mid-thigh muscle. Moreover, women with more fat-rich muscle had many features of the metabolic syndrome. These relations were weakened when visceral adipose tissue was taken into account sugges...
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PMID: 20698803
PDF is available here.
PDF is available here.
Circulation Journal (74)8 2010
Abstract
Remnant lipoproteinemia is a strong risk factor for cardiovascular (CV) diseases. This study examined which of 2 common lipid-lowering drugs (fibrates and statins) is more effective in patients with remnant lipoproteinemia and if lowering remnant lipoprotein levels can reduce CV risk.
Remnant lipopr...
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PMID: 20574136
PDF is available here.
PDF is available here.
Tumor Biology (31)4 2010
Abstract
We discuss here some of the approaching strategies that include establishing special methods of identifying CSCs and targeting therapies of CSCs....
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PMID: 20336402
PDF is available here.
PDF is available here.
Abstract
Abstract
We have identified a monomer with the low plasma values of CRP and its bulk (this is a pentamere) with its high plasma values....
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PMID: 20891039
PDF is available here.
PDF is available here.
Zhen ci yan jiu = Acupuncture research / [Zhongguo yi xue ke xue yuan Yi xue qing bao yan jiu suo bian ji] (35)4 2010
Abstract
To compare the effects of electroacupuncture (EA) of Shu-acupoint "Weishu" (BL 21), Mu-acupoint "Zhongwan" (CV 12) and BL 21 + CV 12 on serum large molecular metabolites in functional dyspepsia (FD) rats.
A total of 50 Wistar rats were randomly divided into control, model, BL 21, CV 12 and BL 21 + C...
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PMID: 21090332
PDF is available here.
PDF is available here.
Infection and Immunity (78)8 2010
Abstract
We examined the virulence of an R(low) Delta MGA0674 mutant (P1H9) in vivo and observed reduced recovery and attenuated virulence in the tracheas of experimentally infected chickens. The virulence of two additional R(low) Delta MGA0674 mutants, 2162 and 2204, was assessed in a second in vivo virulen...
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PMID: 20515935
PDF is available here.
PDF is available here.
Thrombosis and Haemostasis (104)2 2010
Abstract
We investigated thrombin generation profiles in RA patients and their dependence on plasma factor/inhibitor composition. Plasma factor (F) compositions (II, V, VII, VIII, IX, X), antithrombin and free tissue factor pathway inhibitor (TFPI) from 46 consecutive RA patients with no cardiovascular event...
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PMID: 20593110
PDF is available here.
PDF is available here.
Thrombosis and Haemostasis (104)2 2010
Abstract
We measured total TFPI in a nested case-control study in the Longitudinal Investigation of Thromboembolism Etiology. Control subjects were frequency matched 2:1 to cases on age, sex, race, and cohort. Odds ratios (ORs) for VTE by TFPI levels were computed using logistic regression models adjusting f...
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PMID: 20431849
PDF is available here.
PDF is available here.
Abstract
The atherosclerotic process starts at an early age and is linked to obesity. However, the exact pathophysiological mechanism is poorly understood.
To investigate the relationship between serum adiponectin and metabolic syndrome and early arteriosclerosis.
176 obese and 88 normal children.
Ultrasound...
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PMID: 21073115
PDF is available here.
PDF is available here.
Abstract
We evaluated the changes of lipidic and coagulative pattern during menopause and the influence of hormone replacement therapy (HRT) on these parameters.
We considered 158 patients divided into 2 groups: Group I consisted of 127 women in physiological/surgical menopause and Group II of 31 women with...
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PMID: 20671654
PDF is available here.
PDF is available here.
Nippon Saikingaku Zasshi (65)2-4 2010
Abstract
Biochemical Journal (429)2 2010
Abstract
We summarize basic information on the lipid composition and distribution in zebrafish tissues, including lipoprotein metabolism, intestinal lipid absorption, the yolk lipids and their mobilization, as well as lipids in the nervous system. We also discuss studies in which zebrafish have been employed...
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PMID: 20578994
PDF is available here.
PDF is available here.
Abstract
These results suggest that ART interruption does not favorably influence overall lipid profile: there was little net effect on total/HDL cholesterol ratio, and no change in small LDL-p or small HDL-p, the lipoprotein particle subclasses most consistently linked to coronary risk. Short-term declines...
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PMID: 20658749
PDF is available here.
PDF is available here.
Abstract
It is unclear whether plant stanols lower serum LDL-cholesterol concentrations and cholesterol-standardized fat-soluble antioxidant concentrations dose-dependently when consumption exceeds the recommended daily intakes of 2.0-3.0 g.
The objective was to study the rela...
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PMID: 20504972
PDF is available here.
PDF is available here.
Abstract
These results reveal LppT as the first candidate of a RGD lectin in Mycoplasma species that is assumed to bind to beta integrins....
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PMID: 20494988
PDF is available here.
PDF is available here.
Abstract
In humans, about 50 ABC proteins play physiologically important roles. Many ABC proteins are involved in lipid outward translocation and lipid homeostasis in the body, and defects in their functions cause various diseases. However, the precise mechanisms of substrate transport remain unclear. In bac...
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PMID: 20412807
PDF is available here.
PDF is available here.
Abstract
The enormous burden of vascular disease is likely to expand rapidly as sedentary obesity and diabetes increase. Although cholesterol plays a major role in atherosclerosis and LDL is the major carrier of cholesterol in the blood, the importance of the postprandial triglyceride-rich lipoproteins in th...
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PMID: 20602562
PDF is available here.
PDF is available here.
Abstract
Typically, chylothorax is a milky exudate with high triglyceride content (>110 mg/dl). However, milky appearance is not always the case and triglyceride levels can be less than 110 mg/dl, especially in fasting or malnourished patients. Transudative chylothoraces have been reported when cirrhosis, ne...
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PMID: 20410823
PDF is available here.
PDF is available here.
Abstract
Niacin treatment caused a moderate increase in the ability of HDL to promote net cholesterol efflux, whereas inhibition of cholesteryl ester transfer protein via anacetrapib led to a more dramatic increase in association with enhanced particle functionality at higher HDL concentrations. All HDLs exh...
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PMID: 20448206
PDF is available here.
PDF is available here.
Abstract
The expression of human D374Y PCSK9 at physiological levels produced a phenotype that closely matched that found in heterozygous D374Y patients and suggested that reduced low-density lipoprotein receptor activity is not the sole cause of their hypercholesterolemia....
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PMID: 20448210
PDF is available here.
PDF is available here.
Abstract
We hypothesized that inhibition of the tissue factor pathway would result in attenuation of pathophysiologic parameters typically associated with hypoxia-induced PH. We tested this hypothesis using a chronic hypoxia-induced murine model of PH using mice that overexpress tissue factor pathway inhibit...
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PMID: 19648471
PDF is available here.
PDF is available here.
Molecular Immunology (47)11-12 2010
Abstract
We show that the rlipo-D1E3 lipoprotein can induce the activation of spleen cells and bone marrow-derived dendritic cells (BM-DCs) in wild-type and TLR4-deficient mice, but not in TLR2(-/-) mice. After analyzing the co-receptor usage of TLR2 using TLR1(-/-) or TLR6(-/-) mice, the TLR2 signaling trig...
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PMID: 20478617
PDF is available here.
PDF is available here.
Abstract
We investigated the expression of these transporters and secretion of their substrates in female control and lactating Sprague Dawley rats and C57BL/6 mice. Expression of Abcg5/Abcg8 mRNA was decreased by 97 and 60% by midlactation in rats and mice, respectively; protein levels of Abcg8 were below d...
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PMID: 20413720
PDF is available here.
PDF is available here.
Abstract
We aimed to elucidate the mechanisms involved in the induction by observing, in human umbilical vein endothelial cells (HUVECs), the phosphorylation of mitogen-activated protein kinases (MAPKs), a major cell signaling system. The level of testosterone regulating several signaling pathways, including...
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PMID: 20442653
PDF is available here.
PDF is available here.
Molecular Microbiology (77)1 2010
Abstract
We studied the mechanism behind this indispensability. We could construct a viable prsA null mutant in the presence of a high concentration of magnesium. Various changes in cell morphology in the absence of PrsA suggested that PrsA is involved in the biosynthesis of the cylindrical lateral wall. Con...
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PMID: 20487272
PDF is available here.
PDF is available here.
Indian Pediatrics (47)7 2010
Abstract
A case-control study was conducted to study the Lipid profile of high risk children (age 2-10 years). There was a significant elevation of total cholesterol (P<0.001) and LDL (P< 0.001). Early dietary and lifestyle modifications can prevent this cascade.
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PMID: 20683118
PDF is available here.
PDF is available here.
Infection and Immunity (78)7 2010
Abstract
We identified NlpI as a novel bacterial determinant contributing to E. coli K1 interaction with HBMECs. The deletion of nlpI did not affect the expression of the known bacterial determinants involved in E. coli K1-HBMEC interaction, such as type 1 fimbriae, flagella, and OmpA, and the contribution o...
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PMID: 20421385
PDF is available here.
PDF is available here.
Infection and Immunity (78)7 2010
Abstract
We evaluated PsaA, a conserved antigen important for S. pneumoniae adhesion to and invasion into nasopharynx epithelia, for its ability to induce protective immunity against S. pneumoniae challenge when delivered by recombinant attenuated Salmonella vaccine (RASVs) strains. RASVs were engineered to...
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PMID: 20479086
PDF is available here.
PDF is available here.
Abstract
Elevated leukocyte cell numbers (leukocytosis), and monocytes in particular, promote atherosclerosis; however, how they become increased is poorly understood. Mice deficient in the adenosine triphosphate-binding cassette (ABC) transporters ABCA1 and ABCG1, which promote cholesterol efflux from macro...
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PMID: 20488992
PDF is available here.
PDF is available here.
Abstract
Abstract
We found that the -287C and -399T alleles affected the activity of the promoter using a reporter gene system. This was also the case for the -33T/C polymorphism. An association regarding the transcriptional activity of the reporter gene was detected between the -287C allele and the -33T/C polymorphi...
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PMID: 20519147
PDF is available here.
PDF is available here.
Abstract
Because atherosclerosis, a leading cause of morbidity and mortality in women, is thought of as a sterol (cholesterol and noncholesterol sterol)-mediated disease, plasma triglyceride (TG) levels (the concentration of all TG trafficked within all of the lipoproteins per dL of plasma), TG biology, and...
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PMID: 20638625
PDF is available here.
PDF is available here.
The Aging Male (13)2 2010
Abstract
Patients with PCa showed higher TG/HDL-chol and diminished HDL-chol than Controls and BPH. PSA correlated inversely with HDL-chol and directly with TG/HDL-chol. FAI, FT, BioT and estradiol levels were higher, and SHBG and adiponectin were lower in PCa than in Controls. No differences were found in a...
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PMID: 19921964
PDF is available here.
PDF is available here.
Abstract
We found that B. burgdorferi populations in the Northeast and Midwest shared a recent common ancestor, which suggests that substantial evolutionary divergence in human invasiveness has not occurred. We propose that differences in either animal ecology or human behavior are the root cause of the diff...
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PMID: 20507740
PDF is available here.
PDF is available here.
Abstract
Adverse lipoprotein patterns were found in patients with MDD. The fact that these associations diminished after adjustment for lifestyle-related factors, especially BMI, suggests that the unfavorable lipid/lipoprotein pattern among depressed subjects is mainly secondary to lifestyle-related factors....
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PMID: 20021996
PDF is available here.
PDF is available here.
Abstract
A high performance liquid chromatography system with a gel permeation column (GP-HPLC) and an on-line dual enzymatic system was applied to lipoprotein analysis in dogs. A high density lipoprotein (HDL) fraction obtained by conventional ultracentrifugation gave a single peak at around 28-29 min. Simi...
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PMID: 20145378
PDF is available here.
PDF is available here.