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Drug Resistance, Bacterial (7):
Recent article
Drug Resistance, Bacterial
Abstract
C. difficile associated diarrhea (CDAD) is now considered to be one of the commonest causes of nosocomial diarrhea. CDAD, once considered to be a "nuisance" disease, has lately become a "killer" disease with appearance of a hypervirulent strain, toxinotype III. Although the incidence and severity of...
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PMID: 21922851
PDF is available here.
PDF is available here.
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Abstract
We identify a previously unknown target of POA as the ribosomal protein S1 (RpsA), a vital protein involved in protein translation and the ribosome-sparing process of trans-translation. Three PZA-resistant clinical isolates without pncA mutation harbored RpsA mutations. RpsA overexpression conferred...
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PMID: 21835980
PDF is available here.
PDF is available here.
Abstract
Incorrect use of antibiotics is a major public health concern both nationally and globally due to the development of antibiotic resistance. The goal of this study was to see if prescription of antibiotics for urinary tract infections in general practice was in accordance with national guidelines.
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PMID: 21901035
PDF is available here.
PDF is available here.
Abstract
Quality-assured worldwide surveillance of antimicrobial resistance (AMR) in Neisseria gonorrhoeae is crucial for public health purposes. In the countries of the eastern part of the WHO European region the knowledge regarding gonococcal AMR is limited, and antimicrobials of many different types, sourc...
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PMID: 21851423
PDF is available here.
PDF is available here.
Abstract
These results showed that these pathogens can be transmitted by human activities, other wild animals, and the environment to feral raccoons and masked palm civets, and vice versa. As these animals have omnivorous behaviour and a wide range of habitats, they can play an important role in the transmis...
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PMID: 21824337
PDF is available here.
PDF is available here.
Saudi medical journal (32)9 2011
Abstract
Abstract
We have previously identified the ter operon (terXYW and terZABCDEF) of the uropathogenic strain Escherichia coli KL53. In this study, we use an innovative approach to identify putative protein-protein interaction partners for one of the essential tellurite resistance proteins - TerB. We observe tha...
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PMID: 21952438
PDF is available here.
PDF is available here.
Abstract
The Lancet (378)9790 2011
Abstract
The Lancet (378)9790 2011
Abstract
The Lancet (378)9790 2011
Abstract
Scientific American (305)2 2011
Abstract
Audio, Transactions of the IRE Professional Group on (53 Suppl 1) 2011
Abstract
We review the existing data on ASPs and their effects on patient care and antimicrobial resistance, as well as strategies for establishing ASPs in different types of hospitals....
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PMID: 21795725
PDF is available here.
PDF is available here.
Veterinary Record (169)3 2011
Abstract
Abstract
There has been an increase in the number of foreign-born tuberculosis (TB) patients residing in Japan. The purpose of this study is to clarify the clinical features of the foreign-born TB patients treated at our hospital.
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PMID: 21922779
PDF is available here.
PDF is available here.
Abstract
We conducted a double-blind, randomized, placebo-controlled trial of preexposure isoniazid prophylaxis against tuberculosis in HIV-infected children and uninfected children exposed to HIV during the perinatal period.
We randomly assigned 548 HIV-infected and 804 HIV-uninfected infant...
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PMID: 21732834
PDF is available here.
PDF is available here.
Abstract
Abstract
We should pay attention and caution on outbreaks by Acinetobacter and spread of drug-resistant Acinetobacter as much as we can....
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PMID: 21861436
PDF is available here.
PDF is available here.
Abstract
Health care-associated pneumonia is a relatively new classification of pneumonia that includes community-dwelling pneumonia patients having contact with the health care system. Current data indicate that health care-associated pneumonia patients present with more severe disease, are more likely to be...
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PMID: 21663884
PDF is available here.
PDF is available here.
Abstract
Various studies have shown the potentially beneficial biological activities of cyclic dipeptides and in particular, cyclo(L-tyrosyl-L-prolyl) (cyclo(Tyr-Pro)) has shown fair antibacterial activity in vitro. This study aimed to determine if liposome encapsulation would have any significant effects on...
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PMID: 21699080
PDF is available here.
PDF is available here.
Abstract
Abstract. Stool samples from children < 5 years of age with diarrhea (N = 239) were examined for enteric pathogens using a combination of culture, enzyme-immunoassay, and polymerase chain reaction methods. Pathogens were detected in 122 (51%) stool samples; single pathogens were dete...
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PMID: 21633024
PDF is available here.
PDF is available here.
Abstract
Clarithromycin resistance has decreased the eradication rates of Helicobacter pylori.
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PMID: 21766091
PDF is available here.
PDF is available here.
Abstract
Approximately two-thirds of the patients with severe sepsis or septic shock are first encountered in the emergency departments (EDs) of western countries, in which bacteremia is present in about 50% of patients with severe sepsis. The situation of bacteremia presenting to the EDs in...
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PMID: 21524617
PDF is available here.
PDF is available here.
Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale (40)3 2011
Abstract
To examine the yield and resistance profile of pathogens in chronic rhinosinusitis (CRS) patients receiving culture-directed management and to pay particular attention to the prevalence of methicillin-resistant Staphylococcus aureus (MRSA) in this population.
Retrospe...
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PMID: 21518646
PDF is available here.
PDF is available here.
Abstract
We performed an agglutination assay. Agglutination in DL treated H. pylori suspension suggested selectivity of DL towards the PE surface receptor of H. pylori. Monotherapy is generally not recommended for treatment of a H. pylori infection due to the danger of development of resistance and unaccepta...
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PMID: 21699071
PDF is available here.
PDF is available here.
Abstract
While most systemic pediatric Haemophilus influenzae infections are caused by the type b strain (Hib), nontypeable H. influenzae: (NTHi) has been considered a respiratory tract pathogen common in local infection such as acute otitis media, acute pneumonia, secondary chronic respiratory disease and ot...
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PMID: 21706841
PDF is available here.
PDF is available here.
Abstract
We used multilocus PCR and electrospray ionization mass spectrometry (PCR/ESI-MS) to determine the genotype and drug resistance profiles for 96 Mycobacterium tuberculosis isolates circulating in regions of high and low tuberculosis (TB) endemicity in China. The dominant principal genetic group (PGG)...
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PMID: 21525214
PDF is available here.
PDF is available here.
Abstract
Abstract
Pseudomonas aeruginosa is a Gram-negative bacillus that is most frequently associated with opportunistic infection, but which can also present in the otherwise healthy patient. The range of P. aeruginosa infections varies from localized infections of the skin to life-threatening systemic disease. Man...
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PMID: 21469761
PDF is available here.
PDF is available here.
Abstract
Abstract
We describe a case of NDM-1 infection in an immunocompromised foreign patient, and discuss its implications....
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PMID: 21552793
PDF is available here.
PDF is available here.
Abstract
We collected the 85 strains that were believed to be aac(6')-Ib positive from clinical isolates. Among them, 38 strains were the wild-type; the remaining 47 strains were the aac(6')-Ib-cr variant. Of these 47 strains, 19 simultaneously harbored aac(6')-Ib and aac(6')-Ib-cr. Our study aims to report...
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PMID: 21524352
PDF is available here.
PDF is available here.
Abstract
We have conducted studies on the drug resistance through docking and binding analysis supported by time-scale (∼ 1000 ps) and unrestrained all-atom molecular dynamics simulations of wild and mutant MtBKatG. The study showed conformational changes of binding residues. Mutant (S315T) showed high doc...
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PMID: 20593210
PDF is available here.
PDF is available here.
Abstract
We developed a microbiology data warehouse for networking hospital laboratories in Akita prefecture. This system, named Akita-ReNICS, is an easy-to-use information management system designed to compare, track, and report the occurrence of antimicrobial-resistant organisms. Participating laboratories...
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PMID: 21626877
PDF is available here.
PDF is available here.
Abstract
Abstract
A total of 91 of 1,480 invasive isolates (6.1%) collected from adults in Barcelona, Spain, in the period of 1994 to 2008 were of serogroup 6 (6B, 47 isolates; 6A, 28; and 6C, 16). Throughout this period, serotype 6B (Spain(6B)-ST90) decreased, and serotype 6A remained stable. An increase in serotype...
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PMID: 21450964
PDF is available here.
PDF is available here.
Abstract
We performed species identification, examined the antibiotic resistance profiles, and determined the mechanisms of resistance and clonal relationships of 123 Acinetobacter isolates obtained from inmates of 20 California correctional facilities (CCFs). We found that 57.7% of the isolates belong to A....
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PMID: 21450955
PDF is available here.
PDF is available here.
Abstract
The cichlid oscar Astronotus ocellatus has worldwide commercial value in the pet fish industry because of its early maturation, relatively high fecundity, ability to identify its caretaker and also to alter colouration amongst conspecifics. Pathogenic strains of Aeromonas veronii res...
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PMID: 21553566
PDF is available here.
PDF is available here.
Abstract
We report the properties and the recent developments of quinoxaline 1,4-di-N-oxide derivatives as potential anti-tuberculosis agents. Specific agents are reviewed that have excellent antitubercular drug properties, are active on drug resistant strains and non-replicating mycobacteria. The properties...
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PMID: 21470099
PDF is available here.
PDF is available here.
Abstract
We identified clinical isolates of Nocardia species by genetic methods and analyzed clinical features of nocardiosis. Nine clinical isolates were obtained in Kyushu University Hospital from 2005 to 2008. Six different Nocardia species were identified by 16Sr RNA: Nocardiafarcinia (n=2), Nocardia bra...
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PMID: 21560401
PDF is available here.
PDF is available here.
Journal of wound care (20)3 2011
Abstract
The sizes of the corrected zones of inhibition varied between and within genera. For example, all Acinetobacter baumannii strains were found to be sensitive to ionic silver at pH 7, with a mean of 2.8mm, compared with 3.5mm at pH 5.5. The silver alginate dressing also demonstrated activity on all st...
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PMID: 21537295
PDF is available here.
PDF is available here.
Leprosy Review (82)1 2011
Abstract
Abstract
We suggested this maybe attributed to the resistivity of the resistant strains to the treatment and consequently prolonged the symptoms and compromised the disease in patients....
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PMID: 21377522
PDF is available here.
PDF is available here.
Abstract
: Although chronically ventilated patients with HAIA have longer ventilator days, higher antibiotics resistance, and high rate per 100 patients of ventilator-associated pneumonia, most patients are treated well. Compared with patients without HAIA, prolonged ventilation days and inappropriate empiric...
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PMID: 21289504
PDF is available here.
PDF is available here.
Abstract
We report the results of 2009 surveillance with emphasis in its interpretation, limitations and future perspectives....
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PMID: 21526281
PDF is available here.
PDF is available here.
Abstract
Nosocomial infection is most commonly registered in the traumatology and surgery units, primarily in the intensive care unit (ICU) that is considered to be an increased risk unit owing to a large number of performed manipulations and the extensive empirical use of antibiotics. In ICU patients with no...
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PMID: 21509988
PDF is available here.
PDF is available here.
Abstract
The post-marketing surveillance of meropenem for children was conducted between May 2004 and September 2006. The safety and the efficacy were analyzed in 1210 cases and 1004 cases, respectively. The results of this surveillance were as follows: The incidence of adverse drug reactions...
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PMID: 21612039
PDF is available here.
PDF is available here.
Abstract
Carbapenems are the drugs of choice for the treatment of serious infections caused by ESBL- and AmpC-positive Enterobacteriaceae. An increasing trend of resistance to these antibiotics has been observed recently. The aim of the study was to determine resistance to carbapenems in clinical isolates of...
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PMID: 21452118
PDF is available here.
PDF is available here.
Epidemiologie, mikrobiologie, imunologie : casopis Spolecnosti pro epidemiologii a mikrobiologii Ceske lekarske spolecnosti J.E. Purkyne (60)1 2011
Abstract
To analyze trends in the resistance of Streptococcus pneumoniae to penicillin and macrolides and of S. pyogenes to macrolides over a 14-year period and to determine serotypes and molecular characteristics in a selected group of S. pneumoniae strains resistant to these antibiotics.
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PMID: 21542231
PDF is available here.
PDF is available here.
Abstract
A total 113 episodes of bacteremia caused by E coli (59.3%), K pneumoniae (39.8%) or both (0.9%) were included. Patients with hematological malignancy were younger (55±22 vs. 69±14 years, p<0.003) and had less co-morbidity, but were more likely to have neutropenia (73.1% vs. 4.6%, p<0.001) than th...
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PMID: 21524962
PDF is available here.
PDF is available here.
Lakartidningen (108)3 2011
Abstract
Lakartidningen (108)22-23 2011
Abstract
Abstract
Clinical microbiologists are highly skilled scientists within national hospitals and reference laboratories who diagnose patients with infections by emerging pathogens. Most advanced training for clinical microbiologists occurs at universities, where an individual can receive certification as a "Medi...
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PMID: 21905578
PDF is available here.
PDF is available here.
Abstract
We found that a systemic strain of C. jejuni, isolated from the cerebrospinal fluid of an infant with meningitis, is relatively more resistant to human serum, the Bactericidal/Permeability-Increasing Protein (BPI), an endogenous cationic antimicrobial protein, and the cationic peptide antibiotic pol...
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PMID: 21266840
PDF is available here.
PDF is available here.
Abstract
I (4, 3.08%), LAM (2, 1.54%), X (N = 1, 0.77%) and S (2, 1.54%). Nine isolates had SIT numbers with no identified sub-lineages while 17 had no SIT numbers. MTBss isolates were more likely to be resistant to streptomycin (p<0.008) and to any drug resistance (p<0.03) when compared to M. africanum....
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PMID: 21779354
PDF is available here.
PDF is available here.
Abstract
We systematically reviewed published studies on drug-resistant TB in China until March 31, 2011, and quantitatively summarized prevalence and patterns of anti-TB drug resistance among new cases and previously treated cases, respectively.
Ninety-five eligible articles, published durin...
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PMID: 21674033
PDF is available here.
PDF is available here.
Abstract
Abstract
Pseudomonas aeruginosa produces multiple virulence factors that have been implicated in pathogenesis and quorum sensing. The aim of this study was to determine differences in the virulence factors of pigmented and non-pigmented P aeruginosa isolates.
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PMID: 21809707
PDF is available here.
PDF is available here.