Abstract
A key step during the synthesis of collagen constructs is the incubation of monomeric collagen in phosphate buffer saline (PBS) to promote fibrillogenesis in the collagen network. Optimal PBS-treatment conditions for monomeric collagen solutions to induce gelation are well establishe...
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PMID: 21540522
PDF is available here.
Abstract
Tendon disorders are common clinical conditions. Tendon tissue engineering provides a new approach for tendon repair by integrating engineered substitutes with their native counterparts. Silk is considered to be a promising candidate for tendon engineering because of its biological a...
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PMID: 21555843
PDF is available here.
Abstract
Tenosynovitis is common in rheumatoid arthritis (RA) but knowledge is limited regarding its response to anti-inflammatory treatment. This study used ultrasonography (US) to examine the distribution and responsiveness of tenosynovitis to anti-tumour necrosis factor (anti-TNF) treatmen...
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PMID: 21091275
PDF is available here.
Abstract
Two novel, bionanocomposite scaffolds were evaluated in a rodent model over the course of three months to determine whether these scaffolds possessed adequate biocompatibility characteristics to warrant further evaluation as possible tissue reconstruction scaffolds. These bionanocomp...
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PMID: 21210516
PDF is available here.
Abstract
The authors' purpose was to study the anatomy of the dorsum of the foot and determine the distribution and caliber of all vascular branches that nourish the skin and the extensor hallucis longus and extensor digitorum longus tendons.
The authors performed 20 cadaver dissections. The skin paddle was...
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PMID: 21124141
PDF is available here.
Abstract
Tendinopathy of the long head of the biceps brachii encompasses a spectrum of pathology ranging from inflammatory tendinitis to degenerative tendinosis. Disorders of the long head of the biceps often occur in conjunction with other shoulder pathology. A thorough patient history, physical examination...
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PMID: 21041799
PDF is available here.
Abstract
Reported healing rates of a subscapularis tenotomy have been extremely variable in the literature. The purpose of this study was to document the subscapularis healing rate after subscapularis tenotomy using ultrasound, and to correlate healing with physical examination findings and shoulder internal...
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PMID: 20510631
PDF is available here.
Abstract
To provide the anatomic evidences and the choice of tendon graft for anatomic reconstruction of posterolateral complex through the morphological and biomechanical study on posterolateral structures of the knee in normal adult cadavers.
Twenty-three fresh lower limb specimens from voluntary donators...
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PMID: 21046807
PDF is available here.
Abstract
The purpose of the present study was to examine musculotendinous stiffness (MTS) and ankle joint range of motion (ROM) in men and women after an acute bout of passive stretching. Thirteen men (mean ± SD age = 21 ± 2 years; body mass = 79 ± 15 kg; and height = 177 ± 7 cm) and 19 women (21 ± 3 ye...
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PMID: 20885189
PDF is available here.
Abstract
Posterolateral rotatory instability of the elbow may be a cause of significant impairment of daily activities. The diagnosis is a clinical one, based on the history and physical examination. Imaging studies are often inconclusive because of the variable anatomy of the radio-ulnohumeral ligamentous c...
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PMID: 20883900
PDF is available here.
Abstract
We studied the effects of mechanical stretching on the cell morphology and mRNA expression of several key genes modulating tendon/ligament genesis. We demonstrate that bone-marrow-derived rat MSCs (rMSCs), when subjected to cyclic uniaxial stretching, express obvious detectable mRNAs for tenascin C...
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PMID: 21141679
PDF is available here.
Abstract
We thoroughly analyze the linear propagation effects that affect polarization-resolved Second Harmonic Generation imaging of thick anisotropic tissues such as collagenous tissues. We develop a theoretical model that fully accounts for birefringence and diattenuation along the excitation propagation,...
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PMID: 20940829
PDF is available here.
Abstract
We report the development of a miniaturized dual-optical-zone endoscope objective lens. The lens has two foci, with 0.18 and 0.50 NAs. We demonstrate multiphoton imaging with dual fields of view and resolutions using the new lens. A combination of multiphoton and single-photon microscopic imaging is...
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PMID: 20717440
PDF is available here.
Abstract
To study the effect of platelet-derived growth factor-BB (PDGF-BB) gene transfected rat tendon cells on the healing and adhesion of rat tendon.
A model of heel tendon injury was reproduced in 90 rats. They were randomly divided into three groups: experiment group [with injection of 20 µL rat tendon...
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PMID: 21029687
PDF is available here.
Abstract
We evaluated the accuracy of sonography for identifying the intracompartmental septum in the first extensor compartment in patients with de Quervain's disease using surgical findings as the reference standard.
We performed surgical release of the first extensor compartment in 43 wris...
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PMID: 20033358
PDF is available here.
Abstract
These results indicate that elevated cyclical mechanical loading of tendon quickly results in altered biochemical tissue responses indicative of tissue injury. More sustained cyclical loading over time may be required for these initial responses to induce more dramatic tissue changes as observed in...
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PMID: 20175712
PDF is available here.
Abstract
The aim of this study was to evaluate if spontaneous (nonforced active) exercise and age (maturation process) alter the biomechanical and biochemical properties of superficial digital flexor tendon. Chickens aged 1, 5, and 8 months were divided into two groups: caged and penned. The caged group was...
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PMID: 20175711
PDF is available here.
Abstract
There is still controversy about the effect of anabolic steroid on connective tissue. This study examines the hypothesis that the local use of nandrolone decanoate, an anabolic steroid on rotator cuff, facilitates the healing process when used in combination with surgical repair.
Forty-eight male ra...
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PMID: 20690845
PDF is available here.
Abstract
To explore the value of color Doppler ultrasound in evaluating the therapeutic effects on ankylosing spondylitis (AS) patients.
Color Doppler high-frequency ultrasound images and blood flow in 30 healthy volunteers and 50 AS patients, changes of high-frequency ultrasound images and blood flow of inv...
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PMID: 20979907
PDF is available here.
Abstract
Reconstruction of the anterior cruciate ligament using the double bundle technique provides better covering of the anatomic insertion site areas and fiber length change behavior. Biomechanical studies and intraoperative measurements with computer navigation systems document increased stability in pa...
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PMID: 20567798
PDF is available here.
Abstract
I study which demonstrates cartilage protection by ACL reconstruction as long as the meniscus is intact at index surgery, shown by bilateral MRI analysis 9 years post-operation. There was no significant difference in the average grade of chondral and meniscus lesions between BPT and HT and in compar...
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PMID: 20607509
PDF is available here.
Abstract
Anterior cruciate ligament (ACL) reconstruction using autologous tendons (BTB patellar tendon, hamstrings, quadriceps tendon) in an implant-free fixation technique is becoming more and more popular due to biological and economical reasons. In 1987 an implant-free press-fit fixation technique of a BT...
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PMID: 20607510
PDF is available here.
Abstract
Press-fit fixation of anterior cruciate ligament autografts is an interesting technique because no hardware is necessary. A total of 168 cadaveric human patellar, quadriceps and hamstring tendons (average age 49.2 +/- 18.5 years) were used and 15 different fixation methods were tested. Constructs we...
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PMID: 20607511
PDF is available here.
Abstract
Angular displacement at a 2 Nm level torque was significantly greater in the sectioned group compared to the deltoid reconstruction group in external rotation and eversion (p = 0.006 and p = 0.017 respectively). There was no statistical difference in angular displacement between the deltoid intact a...
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PMID: 20663434
PDF is available here.
Abstract
In addition to the myotendinous junctions, muscle fibers also are connected to the extracellular matrix along their full peripheral length. Moreover, within the in vivo context, muscle is not an isolated entity. Instead, myofascial tissues connect muscles mechanically to neighboring muscular and non...
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PMID: 20577061
PDF is available here.
Abstract
Anterior cruciate ligament (ACL) deficiency alters 6 degrees of freedom knee kinematics, yet only anterior translation and internal rotation have been the primary measures in previous studies.
To compare the 6 degrees of freedom knee kinematics and the graft forces af...
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PMID: 20392968
PDF is available here.
Abstract
Several trials have compared the clinical results between anatomic double-bundle and single-bundle anterior cruciate ligament reconstruction procedures. However, it remains controversial whether the anatomic double-bundle procedure is superior to the single-bundle procedure....
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PMID: 20423987
PDF is available here.
Abstract
We generated Mkx(-/-) mice. These mice had hypoplastic tendons throughout the body. Despite the reduction in tendon mass, the cell number in tail tendon fiber bundles was similar between wild-type and Mkx(-/-) mice. We also observed small collagen fibril diameters and a down-regulation of type I col...
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PMID: 20498044
PDF is available here.
Abstract
To present the properties of an eccentric contraction and compare neuromuscular and muscle-tendon system adaptations induced by isotonic and isokinetic eccentric trainings.
An eccentric muscle contraction is characterized by the production of muscle force associated to a lengthening of the muscle-te...
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PMID: 20542752
PDF is available here.
Abstract
We have developed a seeding system whereby collagen fibrils were isolated from avian embryonic tendon and added to purified collagen solution, in order to characterise fibril surface nucleation and growth mechanisms. Fragmentation of tendon in liquid nitrogen followed by Dounce homogenisation genera...
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PMID: 20385142
PDF is available here.
Abstract
We conclude that mature human tendon fibroblasts retain an intrinsic capability to perform collagen fibrillogenesis similar to that of developing tendon, which implies that the hormonal/mechanical milieu, rather than intrinsic cellular function, inhibits regenerative potential in mature tendon.
(c)...
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PMID: 20356622
PDF is available here.
Abstract
The results show that this technique provides a detailed mapping of the regions of the complex flexor muscle compartments that correspond to each digit for both the flexor digitorum profundus and the flexor digitorum superficialis. The results also demonstrate the presence of mechanical interdepende...
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PMID: 20512892
PDF is available here.
Abstract
Posttraumatic instability of the elbow in children can be a very challenging problem to diagnose and treat. Posterolateral rotatory instability (PLRI) has been well described with regard to diagnosis and treatment in adults but best clinical practices are less clear for pediatric cases. Children wit...
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PMID: 20526166
PDF is available here.
Abstract
We concluded that obesity provokes alterations in the composition and organization of tendon extracellular matrix components. These alterations might be related to organizational and structural modifications in the collagen bundles, influencing the mechanical properties of the tendon and the progres...
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PMID: 20073987
PDF is available here.
Abstract
We reviewed the prevalence of unilateral and bilateral absence of superficialis function in the published literature. In appropriate studies identified (1352 people), the anomaly was unilateral in 92 individuals (6.8%) and bilateral in 81 (6.0%). If superficialis function is absent in one little fin...
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PMID: 20515987
PDF is available here.
Abstract
The semitendinosus tendon DB revision procedure provided range of motion and anterior stability comparable to those after primary DB surgery and a comparable return to athletic activities. However, the patients tended to have positive pivot-shift test results. The revision cases were also inferior i...
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PMID: 20511035
PDF is available here.
Abstract
The zone 2 FHL tendon sheath can be subdivided into a proximal fibrous zone (2A) and a distal fascial zone (2B). Because of the close proximity of the medial plantar nerve to the tendon sheath, there is a significant risk of iatrogenic nerve injury when surgical procedures are performed in zone 2B....
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PMID: 20511039
PDF is available here.
Abstract
The EndoButton provided the strongest ACL femoral fixation with significantly less graft-implant elongation and significantly higher failure loads. It was also shown in a porcine model that implants on the anterior cortical surface perform better than those on the lateral surface. Increased cortical...
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PMID: 20511038
PDF is available here.
Abstract
Active motion therapy provides greater active finger motion than passive motion therapy after zone-II flexor tendon repair without increasing the risk of tendon rupture. Concomitant nerve injuries, multiple digit injuries, and a history of smoking negatively impact the final outcome of tendon repair...
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PMID: 20516313
PDF is available here.
Abstract
Treatment with the lubricin-containing gel CHL appears to be an effective means of decreasing postoperative flexor tendon adhesions, but it is also associated with some impairment of tendon healing. Future studies will be necessary to determine if the positive effects of CHL on adhesion formation ca...
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PMID: 20516321
PDF is available here.
Abstract
Although there are sound theoretical reasons for the use of botulinum toxin (Btx) as early as possible in the management of severe childhood muscle spasticity, the experience with its safety in children younger than 2 years of age is limited and information about its possible effects on the developm...
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PMID: 19574925
PDF is available here.
Abstract
Above the chiasma, five specimens had a small amount of fat tissue between the tibialis posterior and flexor digitorum longus tendon. In all specimens both tendons had a sheath below the chiasma but not above it. At the central portion of the chiasma there was no soft tissue between the tendons, exc...
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PMID: 19876626
PDF is available here.
Abstract
OBJECTIVE: Ultrasound is well-established as a safe, efficient, and cost-effective method to evaluate superficial structures about the ankle. The purpose of this video article is to review the anatomy, scanning techniques, and sonographic appearance of the tendons and ligaments of the ankle. CONCLUS...
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PMID: 20489070
PDF is available here.
Abstract
Ultrasound can be used to study tendon movement. However, measurement of tendon movement is mostly based on manual tracking of anatomical landmarks such as the musculo-tendinous junction, limiting the applicability to a small number of muscle-tendon units. The aim of this study was to quantify tendo...
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PMID: 20152983
PDF is available here.
Abstract
We summarize fundamental questions, as well as future directions in tendon biology and tissue engineering. TAKE HOME MESSAGE: Multifaceted technologies are increasingly required to control stem cell differentiation, to develop novel stem cell-based therapy, and, ultimately, to achieve more effective...
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PMID: 20367125
PDF is available here.
Abstract
We describe the case of a rock climber who suffered a forced extension injury to the DIPJ of the right index finger, resulting in traumatic rupture of his anomalous FPL-FDP connecting tendon. This is the first reported case of rupture of a Linburg-Comstock anomaly. Through rupture of this anomalous...
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PMID: 20500997
PDF is available here.
Abstract
The medial approach to image the distal biceps tendon complements previously described techniques and should be considered in the evaluation of patients presenting with distal biceps tendon disorders. Future clinical studies may elucidate the relative advantages and disadvantages of sonographic dist...
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PMID: 20427803
PDF is available here.
Abstract
Sonographic guidance can be used to inject the popliteus tendon sheath with a high degree of accuracy. Although the longitudinal approach is potentially more accurate, both approaches may result in injectate overflow into the knee joint, likely through the popliteus hiatus....
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PMID: 20427790
PDF is available here.