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Welcome to the Pubget Medical Subject Headings (MESH) browser. Click on a topic or subtopic below to explore related papers. In the gold box is the most recent paper about the current MESH term, and below are 20 related papers.
Dimethylpolysiloxanes (1):
Recent article
Dimethylpolysiloxanes
Abstract
Embyroid body (EB) formation is a key step in many embryonic stem cell (ESC) differentiation protocols. The EB mimics the structure of the developing embryo, thereby providing a means of obtaining any cell lineage. Traditionally, the two methods of EB formation are suspension and hanging drop. The s...
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PMID: 21042991
PDF is available here.
PDF is available here.
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Abstract
We designed a strategy to improve the efficiency of cell adhesion using hydrophobic cell culture environment to enhance cells adhering to a scaffold. Cells have lower affinity to the surface of polydimethylsiloxane (PDMS) than tissue culture polystyrene (TCPS) plates. When cells were cultured with g...
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PMID: 21504053
PDF is available here.
PDF is available here.
Abstract
A novel method for high-speed fabrication of large scale periodic arrays of nanoparticles (diameters 40-200 nm) is developed. This method is based on a combination of nanosphere lithography and laser-induced transfer. Fabricated spherical nanoparticles are partially embedded into a p...
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PMID: 21539373
PDF is available here.
PDF is available here.
Abstract
We observe a distinct response for 3T3 fibroblasts and RAW 264.7 macrophages to the topographical cues tested. Attachment and proliferation of fibroblasts was substantially enhanced by increasing pillar height, whereas macrophage adherence is significantly diminished by reduced pillar spacing. When...
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PMID: 21332193
PDF is available here.
PDF is available here.
Abstract
We have used an engineered poly(dimethylsiloxane) (PDMS) microwell array as a reductionist approach to study the effect of environmental parameters, independently of each other. It is observed for MCF-7 breast cancer cells, that culture within the three-dimensional (3D) environment of the microwells...
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PMID: 21049126
PDF is available here.
PDF is available here.
Acta Biomaterialia (7)1 2011
Abstract
We have developed a strategy for cultivating dermal papilla (DP) cells to form multiple arrayed spheroidal microtissues for transplantation on a micropatterned polydimethylsiloxane (PDMS)-based tissue culture polystyrene (TCPS) plate system. We also describe the behavior of dermal papilla cells on t...
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PMID: 20728585
PDF is available here.
PDF is available here.
Lab On a Chip (10)23 2010
Abstract
Mixed-scale nano- and microfluidic networks were fabricated in thermoplastics using simple and robust methods that did not require the use of sophisticated equipment to produce the nanostructures. High-precision micromilling (HPMM) and photolithography were used to generate mixed-scale molding tools...
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PMID: 20938506
PDF is available here.
PDF is available here.
Lab On a Chip (10)23 2010
Abstract
A direct molding method for creating a homogeneous, polymer microfluidic channel is presented. By utilizing capillary rise and subsequent absorption of poly(methyl methacrylate) (PMMA) solution into a solvent-permeable poly(dimethyl siloxane) (PDMS) mold, various circular or elliptic polymer microch...
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PMID: 20938498
PDF is available here.
PDF is available here.
Lab On a Chip (10)23 2010
Abstract
We describe the design, fabrication, and testing of a microfabricated metering rotary nanopump for the purpose of driving fluid flow in microfluidic devices. The miniature peristaltic pump is composed of a set of microfluidic channels wrapped in a helix around a central camshaft in which a non-cylin...
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PMID: 20959938
PDF is available here.
PDF is available here.
Lab On a Chip (10)23 2010
Abstract
We report a low cost, disposable polymer microfluidic sample preparation device to perform rapid concentration of bacteria from liquid samples using enhanced evaporation targeted at downstream detection using surface enhanced Raman spectroscopy (SERS). The device is composed of a poly(dimethylsiloxa...
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PMID: 20938505
PDF is available here.
PDF is available here.
Lab On a Chip (10)23 2010
Abstract
Stretchable electronics is a revolutionary technology that will potentially create a world of radically different electronic devices and systems that open up an entirely new spectrum of possibilities. This article proposes a microfluidic based solution for stretchable radio frequency (RF) electronic...
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PMID: 20877884
PDF is available here.
PDF is available here.
Lab On a Chip (10)22 2010
Abstract
A microfluidic device is presented for the serial formation, storage and retrieval of water microdroplets in oil. The principle of operation is similar to that of an electronic shift register. Droplets, considered as units of information, can be arrayed and serially shifted within the device, allowi...
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PMID: 20856984
PDF is available here.
PDF is available here.
Lab On a Chip (10)21 2010
Abstract
We present an efficient, yet inexpensive, approach for isolating viable single cells or colonies from a mixed population. This cell microarray platform possesses innovations in both the array manufacture and the manner of target cell release. Arrays of microwells with bases composed of detachable co...
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PMID: 20838672
PDF is available here.
PDF is available here.
Optics Express (18)20 2010
Abstract
We propose a new method for implementing 3D/2D convertible feature in the projection-type integral imaging by using concave half mirror array. The concave half mirror array has the partially reflective characteristic to the incident light. And the reflected term is modulated by the concave mirror ar...
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PMID: 20940957
PDF is available here.
PDF is available here.
Lab On a Chip (10)18 2010
Abstract
We describe a control system to automatically distribute antibody-functionalized beads to addressable assay chambers within a PDMS microfluidic device. The system used real-time image acquisition and processing to manage the valve states required to sort beads with unit precision. The image processi...
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PMID: 20593069
PDF is available here.
PDF is available here.
Lab On a Chip (10)18 2010
Precise control over the oxygen conditions within the Boyden chamber using a microfabricated insert.
Abstract
We present a newly developed microfabricated polydimethylsiloxane (PDMS) device that easily adapts to the Boyden chamber, and provides more control over the oxygenation conditions exposed to cells. The device equilibrates to 1% oxygen in about 20 min, thus demonstrating the capabilities of a system...
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PMID: 20689862
PDF is available here.
PDF is available here.
Lab On a Chip (10)18 2010
Abstract
The desire to make microfluidic technology more accessible to the biological research community has led to the notion of "modular microfluidics", where users can build a fluidic system using a toolkit of building blocks. This paper applies a modular approach for performing droplet-based screening, i...
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PMID: 20717617
PDF is available here.
PDF is available here.
Optics Express (18)18 2010
Abstract
We present a new method to make liquid lenses. It is based on the microfluidics method and involves the preparation of emulsions one drop at a time. Tests of lenses by image formation are presented. Experimental results are compared with results of an optical design program. We also present a new ty...
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PMID: 20940763
PDF is available here.
PDF is available here.
Abstract
Targeting of vaccines to abundant immune cell populations within our outer thin skin layers using miniaturized devices-much thinner than a needle and syringe, could improve the efficacy of vaccines (and other immunotherapies). To meet this goal, a densely packed dissolving microprojection array (dis...
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PMID: 20665628
PDF is available here.
PDF is available here.
Abstract
Dental Materials Journal (29)4 2010
Abstract
The purpose of this study was to evaluate the dynamic viscoelastic properties of experimental silicone soft lining materials, Silastic MDX 4-4210 reinforced with silica fillers. Storage modulus (E'), loss modulus (E") and damping factor (tan delta) were determined using a dynamic mechanical analyzer...
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PMID: 20647638
PDF is available here.
PDF is available here.
Abstract
We also found optimal cell growth of single neurons inside individual channels. The first successful cultivation of insect neurons in closed-channel microfluidic devices provides a prerequisite for the development of low density neuronal networks on multi electrode arrays combined with microfluidic...
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PMID: 20566412
PDF is available here.
PDF is available here.
Applied Optics (49)22 2010
Abstract
We present a highly integrated optofluidic system made of polydimethylsiloxane (PDMS). The system is replicated in a single-step process from a micromilled polymethyl methacrylate master mold. It already includes the reservoirs, the channel system, as well as the optical interconnect surfaces for hi...
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PMID: 20676190
PDF is available here.
PDF is available here.
Abstract
Sylgard((R)) is a biocompatible elastomer which has been widely used in biomedical applications including in simulations of the mechanical response of soft tissues and mechanotransduction investigations. In this study the effect of fabrication parameters including base to curing agent ratio and curi...
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PMID: 20621030
PDF is available here.
PDF is available here.
Abstract
A complex profile of volatile organic compounds ("VOC"s) emanates from human skin, which is altered by changes in the body's metabolic or hormonal state, the external environment, and the bacterial species colonizing the skin surface. The aim of this study was to compare VOC profiles sampled from ch...
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PMID: 20492633
PDF is available here.
PDF is available here.
Advanced Materials (FRG) (22)25 2010
Abstract
Abstract
Abstract
We observe exceptionally long-lasting current blockades with a fine structure of distinct current levels, suggesting an attractive interaction between the DNA and the PEGylated metallic pore walls....
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PMID: 20564484
PDF is available here.
PDF is available here.
Abstract
We present a novel approach to control endothelial tubulogenesis by spatially patterning cells within micromolded collagen gels. Endothelial cells cultured within microscale channels that were filled with collagen gel organized into tubes with lumens within 24-48 h of seeding. These tubes extended u...
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PMID: 20180698
PDF is available here.
PDF is available here.
Abstract
We therefore reasoned that a gradient in the inorganic content of a hybrid inorganic-organic scaffold may induce an osteochondral-like transition in cell phenotype and matrix production. To test this hypothesis, hydrogels were prepared from poly(ethylene glycol) (PEG) and star poly(dimethylsiloxane)...
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PMID: 20128006
PDF is available here.
PDF is available here.
Journal of Bacteriology (192)13 2010
Abstract
We examine swarm-cell trajectories and ways in which these trajectories are determined by flagellar motion, visualizing the cell bodies by phase-contrast microscopy and the flagellar filaments by fluorescence microscopy. We distinguish four kinds of tracks, defining stalls, reversals, lateral moveme...
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PMID: 20363932
PDF is available here.
PDF is available here.
Lab On a Chip (10)12 2010
A hybrid microfluidic chip with electrowetting functionality using ultraviolet (UV)-curable polymer.
Abstract
We report a simple, low-cost method to construct such microchannels enclosed between two glass plates, each of which comprises electrodes and insulating layers. Our method uses soft imprint lithography with thiolene precursors to design the channel geometry. UV exposure is used to seal the chips per...
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PMID: 20517557
PDF is available here.
PDF is available here.
Lab On a Chip (10)12 2010
Abstract
A direct fabrication method capable of producing fully-reversible, tunable nanochannel arrays, without the use of a molding step, is described. It is based on tunnel cracking of a readily-prepared brittle layer constrained between elastomeric substrates. The resulting nanochannels have adjustable cr...
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PMID: 20517560
PDF is available here.
PDF is available here.
Lab On a Chip (10)12 2010
Abstract
We introduce a new patterning method for PDMS devices, using integrated oxygen reservoirs fabricated simultaneously with the microfluidic channels, which serve as "chemo-masks". Oxygen diffuses through the PDMS to the nearby channel segments and there inhibits functional polymer growth; by placement...
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PMID: 20454730
PDF is available here.
PDF is available here.
Lab On a Chip (10)11 2010
Abstract
We have demonstrated hybrid integrated PDMS microfluidic systems with fused silica capillaries. The hybrid integrated PDMS microfluidics and silica capillary (iPSC) modules exhibit a novel architecture and method for leakage free CE sample injection merely requiring a single high voltage source and...
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PMID: 20480112
PDF is available here.
PDF is available here.
Lab On a Chip (10)11 2010
Abstract
We report a novel method for fabricating ion-selective membranes in poly(dimethylsiloxane) (PDMS)/glass-based microfluidic preconcentrators. Based on the concept of capillary valves, this fabrication method involves filling a lithographically patterned junction between two microchannels with an ion-...
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PMID: 20480116
PDF is available here.
PDF is available here.
Biomedical Microdevices (12)3 2010
Abstract
We report a simple methodology satisfying these two fundamental but sometimes conflicting issues: primary rat hepatocytes were cultured on polydimethylsiloxane (PDMS) membranes with 3D-pillared microstructures with various dimensions, so that the cells could organize themselves around the pillars in...
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PMID: 20174871
PDF is available here.
PDF is available here.
Optics Express (18)11 2010
Abstract
We show that when a x-cut Iron doped Lithium Niobate (LN) crystal is exposed to appropriate structured laser light, a charge density pattern builds-up in the crystal and a space charge field arise that is able to induce self-patterning of the PDMS liquid film deposited on its surface via the dielect...
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PMID: 20588950
PDF is available here.
PDF is available here.
Lab On a Chip (10)10 2010
Abstract
We perform plastic-PDMS bonding at room temperature, mediated by the formation of a chemically robust amine-epoxy bond at the interfaces. Various plastic materials, such as poly(methylmethacrylate) (PMMA), polycarbonate (PC), polyimide (PI), and poly(ethylene terephthalate) (PET) were adopted as cho...
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PMID: 20445880
PDF is available here.
PDF is available here.
Lab On a Chip (10)10 2010
Abstract
We developed microfluidic-based pure chitosan microfibers (approximately 1 meter long, 70-150 microm diameter) for liver tissue engineering applications. Despite the potential of the chitosan for creating bio-artificial liver chips, its major limitation is the inability to fabricate pure chitosan-ba...
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PMID: 20445889
PDF is available here.
PDF is available here.
Analytica Chimica Acta (667)1-2 2010
Abstract
Partition equilibriums and extraction rates of polycyclic aromatic hydrocarbons (PAHs) were examined for live biomonitoring with oligochaetes (black worms, Lumbriculus variegatus) and for high surface area chemical passive samplers constructed from polydimethylsiloxane thin film. The goals were to b...
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PMID: 20441868
PDF is available here.
PDF is available here.
Abstract
Photochromic spirooxazines functionalized with poly(ethylene glycol) (PEG) and poly(dimethylsiloxane) (PDMS) oligomers were monitored using NMR spectroscopy at temperatures between 193 and 233 K before and after in situ exposure to UV irradiation. NOESY and ROESY experiments reveal the TTC (trans-s-...
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PMID: 20384286
PDF is available here.
PDF is available here.
Nanotechnology (21)18 2010
Abstract
Heparin is a potent anticoagulant agent that interacts strongly with antithrombin III to prevent the formation of fibrin clots. In the present work, poly(dimethylsiloxane)(PDMS)/graphite oxide-benzalkonium chloride-heparin (PDMS/modified graphite oxide) nanocomposite films were obtained by the solut...
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PMID: 20378948
PDF is available here.
PDF is available here.
Biomaterials (31)13 2010
Abstract
We demonstrate (i) the ability to control the diameter of circular cross-sections of microchannels from ca. 40-100 mum; (ii) the fabrication of microchannels with constrictions, and (iii) the capability to grow endothelial cells on the inner surface of the microchannels.
Copyright 2010 Elsevier Ltd...
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PMID: 20167361
PDF is available here.
PDF is available here.
Biomaterials (31)13 2010
Abstract
We have developed a new method for measuring the contractility of engineered cardiovascular smooth and striated muscle in vitro during electrical and pharmacological stimulation. We present a growth theory-based finite elasticity analysis for calculating the contractile stresses of a 2D anisotropic...
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PMID: 20149449
PDF is available here.
PDF is available here.
Analyst (Cambridge UK) (135)5 2010
Abstract
Our method provides a rapid and effective, miniaturized electrochemical analysis platform in Hg(2+) measurement and demonstrates great potential for the application of in situ or on-line mercuric pollutant analysis....
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PMID: 20419250
PDF is available here.
PDF is available here.
Nanotechnology (21)16 2010
Abstract
A microheater was established by embedding magnetic nanoparticles into PDMS (MNP-PDMS). MNP-PDMS generated heat under an AC magnetic field and the temperature was controlled by varying the magnetic particle content and the magnetic field intensity. In this study, the MNP-PDMS chip was demonstrated t...
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PMID: 20351408
PDF is available here.
PDF is available here.
Abstract
A Clark-type oxygen chip consisting of a polydimethylsiloxane (PDMS) reservoir containing an amino group-modified PDMS oxygen-permeable membrane (OPM) and a glass substrate containing a three-electrode detector has been constructed by using microfabrication techniques, and it is utilized for in situ...
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PMID: 20188913
PDF is available here.
PDF is available here.
Abstract
We report here a rapid, simple, and simultaneous immunosensing method for two tumor markers, alpha-fetoprotein (AFP) and carcinoembryonic antigen (CEA), by applying the negative-dielectrophoretic (n-DEP) manipulation of microparticles. Microparticles modified with different antibodies rapidly accumu...
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PMID: 20188978
PDF is available here.
PDF is available here.
Abstract
We demonstrate the immobilization of fluorescent IgG antibodies on stationary PDMS-lipid microbubbles through biotin-avidin interactions and on-chip trapping for immunoassays. A PDMS-lipid composition offers several advantages such as biocompatibility and biodegradability for future in vivo use as p...
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PMID: 20163798
PDF is available here.
PDF is available here.
Abstract
Our own measurements using an imaging ellipsometer, which also clearly shows the presence of a precursor film. The diffusion constant of this film, measured with a 60,000 cS PDMS sample spreading on a hydrophilic silicon wafer is D(f)=1.4x10(-11) m(2)/s. Regardless of their size, density and method...
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PMID: 20144831
PDF is available here.
PDF is available here.
Chemical Communications (46)14 2010
Abstract
Micron-sized hollow spheres with zeolitic shell were used as inorganic fillers in PDMS-based mixed matrix membranes, overall enhancing solvent permeabilities as compared to traditional zeolite fillers, while selectivities were maintained.
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PMID: 20379560
PDF is available here.
PDF is available here.
Abstract
Of the 14 patients, 12 answered the questionnaire and eight could be re-examined after a mean of 12 months. One patient had died, while in another patient the prosthesis had been removed due to pain prior to follow-up. A total of 11 patients had subjectively benefitted from the prosthesis. Symptom-i...
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PMID: 20336270
PDF is available here.
PDF is available here.
Abstract
AFM tips terminated with PMMA colloids are used to pattern molecules in both serial and parallel modes by allowing the polymer on the tip to swell under different humidity conditions. This extension of the dip-pen nanolithography technique provides an easy methodology to place inks on different subs...
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PMID: 20225852
PDF is available here.
PDF is available here.
Chemical Communications (46)13 2010
Nanoliter plates--versatile tools for the screening of split-and-mix libraries on-bead and off-bead.
Abstract
Nanoliter plates are versatile tools for the screening of split-and-mix libraries both on-bead and off-bead. The method was evaluated for the identification of hydrolytically active compounds and enzyme inhibitors.
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PMID: 20234908
PDF is available here.
PDF is available here.
Abstract
We demonstrate experimentally that silver, gold, copper, and aluminum semishells can offer distinct plasmonic responses due to the wide range of their material parameters. Numerical calculations combined with the plasmon hybridization theory render us a clear understanding and assignment of the plas...
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PMID: 20131853
PDF is available here.
PDF is available here.
Biomacromolecules (11)3 2010
Abstract
Inorganic-organic hydrogels with tunable chemical and physical properties were prepared from methacrylated star polydimethylsiloxane (PDMS(star)-MA) and diacrylated poly(ethylene glycol) (PEG-DA) for use as tissue engineering scaffolds. A total of 18 compositionally unique hydrogels...
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PMID: 20146518
PDF is available here.
PDF is available here.
Abstract
We used a high throughput platform to investigate the influence of organic metal oxide doping of polydimethylsiloxane (PDMS) coatings on cellular bioactivity and controlled release of vanadium compared with titanium oxide coatings without additional PDMS. Metal-organic-derived titanium and or vanadi...
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PMID: 19301265
PDF is available here.
PDF is available here.
Dental Materials Journal (29)2 2010
Abstract
This study investigated the C. albicans adhesion to cold- and heat-polymerized soft lining materials that were initially incubated in two different artificial body fluids, namely saliva and nasal secretion, and examined the surface roughness the materials (cold and heat polymerized soft liner) teste...
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PMID: 20379032
PDF is available here.
PDF is available here.
Bioscience Reports (30)3 2010
Abstract
We used benzophenone-initiated photopolymerization to graft PNIPAAm on PDMS substrates to construct the PNIPAAm-grafted PDMS surface and this PDMS surface was highly thermo-responsive. hMSCs (human mesenchymal stem cells) were used to analyse the proliferation and multi-differentiation of stem cells...
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PMID: 19445653
PDF is available here.
PDF is available here.