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Organosilicon Compounds (3):
Recent article
Organosilicon Compounds
Chemical Communications (46)40 2010
Abstract
Metal-free deprotonative functionalization of heteroaromatic compounds was achieved using an organic superbase catalyst; an organosilicon additive such as trimethylsilylpropyne was employed for activating the catalytic cycle of 1,2-addition to carbonyl compounds.
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PMID: 20848038
PDF is available here.
PDF is available here.
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Chemical Communications (46)40 2010
Abstract
Fluorinated polysilsesquioxane (FPSQ) hollow spheres with a large empty interior were synthesized in an aqueous medium by using (trifluoropropyl)trimethoxysilane as the sole precursor. The drug release applications of these spheres were demonstrated, and the materials have great potential as fluorin...
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PMID: 20856943
PDF is available here.
PDF is available here.
Acta Biomaterialia (6)11 2010
Abstract
Calcification currently represents a major cause of failure of biological tissue heart valves. It is a complex phenomenon influenced by a number of biochemical and mechanical factors. Recent advances in material science offer new polymers with improved properties, potentially suitabl...
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PMID: 20601232
PDF is available here.
PDF is available here.
Abstract
We present detailed microscopic analysis of the PEU/POSS matrix and demonstrate its biocompatibility with cell culture. The PEU/POSS polymer forms a continuous porous matrix with open pores and interconnected grooves. From SEM image analysis, it is calculated that there are about 950 pores/mm(2) of...
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PMID: 20213627
PDF is available here.
PDF is available here.
Abstract
In this study, the ability to control the shell thickness of hollow polymeric microspheres prepared using electrohydrodynamic processing at ambient temperature was investigated. Polymethylsilsesquioxane (PMSQ) was used as a model material for the microsphere shell encapsulating a core of liquid perf...
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PMID: 20519216
PDF is available here.
PDF is available here.
Abstract
We speculate that the apoplastic pathway can contribute substantially to the total quantity of QDs reaching the stele. Therefore, based on this transport approach, MAA-coated QDs can be utilized for live imaging in plant systems to verify known physiological processes.
Copyright 2010 Elsevier Masso...
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PMID: 20451401
PDF is available here.
PDF is available here.
Abstract
Chirally functionalized hollow nanospheres with different surface properties were successfully synthesized by co-condensation of (2S,1'R,2'R)-N-tert-butyloxycarbonylpyrrolidine-2-carboxylic acid [2'-(4-trimethoxysilylbenzylamide)cyclohexyl] amide with 1,2-bis(trimethoxysilyl)ethane o...
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PMID: 20509127
PDF is available here.
PDF is available here.
Optics Express (18)10 2010
Abstract
Laser emission from leaky waveguides based in dye-doped organic gain media incorporating Polyhedral Oligomeric Silsesquioxanes (POSS) nanoparticles is reported. The samples consist of thin film gain media deposited onto glass substrate defining a planar asymmetric slab waveguide, which does not inco...
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PMID: 20588878
PDF is available here.
PDF is available here.
Abstract
Cube-octameric silsesquioxane (POSS) based conjugation scaffolds for copper catalysed azide-alkyne [3+2] cycloaddition are reported. The synthetic route to octaazido and octaalkyno functionalised POSS templates without cage rearrangements is described. A set of click couplings is conducted including...
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PMID: 20401398
PDF is available here.
PDF is available here.
Abstract
We describe a Fast Agrobacterium-mediated Seedling Transformation (FAST) technique for transient gene expression analysis in Arabidopsis and other dicot or monocot species. This technique makes use of the cocultivation of young plant seedlings with Agrobacterium in the presence of the surfactant Sil...
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PMID: 20439415
PDF is available here.
PDF is available here.
Abstract
A set of modular components was designed, synthesized, and combined to yield an innovative, robust, and reliable methodology for the self-assembly of large supramolecular structures on silicon wafers. Specific host-guest and H-bonding motifs were embedded in a single molecule by exploiting the remar...
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PMID: 20218712
PDF is available here.
PDF is available here.
Abstract
We present the biological activity of silacaptopril, a silylated analogue of captopril, and its binding affinity towards ACE. Based on the recently determined crystal structures of both the ACE domains, a series of docking calculations were carried out in order to study the structural characteristic...
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PMID: 20014331
PDF is available here.
PDF is available here.
Nanotechnology (20)50 2009
Abstract
A triethanolamine-protected silane, 1-(3'-amino)propylsilatrane, was incorporated into the structure of porphyrin- and ruthenium-based dyes and used to link them to transparent semiconductor nanoparticulate metal oxide films. Silatrane reacts with the metal oxide to form strong, covalent silyl ether...
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PMID: 19923652
PDF is available here.
PDF is available here.
Abstract
We propose that these water-soluble organo-silica nanoparticles will be suitable for biomedical applications....
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PMID: 19783256
PDF is available here.
PDF is available here.
Abstract
We exploit a relatively new nanocomposite of POSS (polyhedral oligomeric silsesquioxane) and PCL [poly(caprolactone-urea)urethane] as a material to develop porous scaffolds using a solvent casting/particulate leaching technique to fabricate porous scaffolds in different pore sizes and porosities. Sc...
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PMID: 19860739
PDF is available here.
PDF is available here.
Abstract
We have developed a biodegradable nanocomposite based on polycaprolactone and polycarbonate polyurethane (PCU) with an incorporated polyhedral oligomeric silsesquioxane (POSS) (POSS modified Poly(caprolactone/carbonate) urethane/urea). Previous work on POSS incorporated into PCU (POSS-PCU) has been...
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PMID: 19051308
PDF is available here.
PDF is available here.
Abstract
We show that the design of the drug carrier can be varied and the release mechanism can be controlled by changing the physical state of the component containing the active agent. The structures formed include loaded micrometer-scale tubes and microcapsules and nanocapsules, which can also be utilize...
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PMID: 19845489
PDF is available here.
PDF is available here.
Abstract
Ir silyl pincer complexes insert into the N-H bonds of anilines and ammonia under mild conditions to form isolable [Cy-PSiP]Ir(H)(NHR) complexes that are resistant to N-H bond reductive elimination at room temperature, even in the presence of arenes, alkenes, and phosphines.
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PMID: 19775090
PDF is available here.
PDF is available here.
Abstract
Full details of an anti-selective catalytic asymmetric nitroaldol reaction promoted by a heterobimetallic catalyst comprised of Nd(5)O(O(i)Pr)(13), an amide-based ligand, and NaHMDS (sodium hexamethyldisilazide) are described. A systematic synthesis and evaluation of amide-based ligands led to the i...
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PMID: 19736990
PDF is available here.
PDF is available here.
Journal of Organic Chemistry (74)19 2009
Abstract
The reaction of (trifluoromethyl)dimethylphenylsilylacetylene and (eta(2)-propene)Ti(O(i)Pr)(2) generated in situ smoothly proceeded giving the corresponding (eta(2)-1-dimethylphenylsilyl-2-trifluoromethylalkyne)Ti(O(i)Pr)(2), which reacted with aldehydes and ketones to afford the corresponding addi...
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PMID: 19715289
PDF is available here.
PDF is available here.
Abstract
Novel azido-functionalized POSS were synthesized, which could serve as nanoprecursors for higher-order molecular construction of organic-inorganic hybrids via"click" chemistry.
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PMID: 20448969
PDF is available here.
PDF is available here.
Abstract
The key designing in reliable biosensors is the preparation of thin films in which biomolecular functions may be immobilized and addressed in a controlled and reproducible manner. This requires the controlled preparation of specific binding sites on planar surfaces. Poly(methylsilsesquioxane)-poly(p...
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PMID: 19572510
PDF is available here.
PDF is available here.
Abstract
The aerial spray program for the eradication of coca in Colombia uses Glyphos, a local formulation of glyphosate tank-mixed with an adjuvant product, Cosmo-Flux. There are some potential risks to amphibians from direct overspraying of shallow waters. In order to evaluate potential al...
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PMID: 19672761
PDF is available here.
PDF is available here.
Organic Letters (11)11 2009
Abstract
We studied the epoxidation of substrates with alpha-methylene groups containing (trans) deuterium labels and discovered that oxygen-atom transfer proceeds with > or = 95% stereospecificity in all cases examined. These and other experiments suggest that the mechanism of epoxidation is not distinguish...
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PMID: 19397300
PDF is available here.
PDF is available here.
Abstract
We hypothesized that poly(L-lysine) (PLL), an analog of the protein catalyst responsible for silica formation in primitive marine species, would remain functional on dentin. PLL was applied to dentin discs along with a pre-hydrolyzed silica precursor, tetramethyl orthosilicate (TMOS). Discs were ana...
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PMID: 19407161
PDF is available here.
PDF is available here.
Klinichna khirurhiia / Ministerstvo okhorony zdorov'ia Ukrainy, Naukove tovarystvo khirurhiv Ukrainy ()5 2009
Abstract
The work objective is the results of complex treatment improvement in patients with diabetic foot syndrome. The work is based on the results of complex treatment analysis data in 32 patients suffering diabetes mellitus, complicated by diabetic foot syndrome. There was proved the efficacy of applicat...
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PMID: 19957747
PDF is available here.
PDF is available here.
Abstract
We investigate the structure of the complex nanohybrids in dependence on pH and salinity. The complexation preserves the original size of the micelles according to dynamic light scattering (DLS) measurements. Cryogenic transmission electron microscopy (cryo-TEM) and Fourier-transform infrared spectr...
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PMID: 19708139
PDF is available here.
PDF is available here.
Abstract
The trifluorosilicon(iv) cation [SiF(3)(Me(3)tacn)](+), isolated as salts with [SiF(5)](-), [B{3,5-(CF(3))(2)C(6)H(3)}(4)](-) or Cl(-), is obtained by reaction of SiF(4) with Me(3)tacn under anhydrous conditions, and compared with the tetrafluoro complexes [SiF(4)(tmeda)] and [SiF(4){kappa(2)-Me(2)N...
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PMID: 19259578
PDF is available here.
PDF is available here.
Abstract
The tetradentate tris(phosphino)silyl ligand [SiP(iPr)(3)] ([SiP(iPr)(3)] = [Si(o-C(6)H(4)P(i)Pr(2))(3)](-)) has been prepared, and its complexation with iron, cobalt, nickel, and iridium precursors has been explored. Several coordination complexes have been thoroughly characterized and are describe...
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PMID: 19209938
PDF is available here.
PDF is available here.
Abstract
The trans-selective hydrosilylation of ynones (1) yields beta-silylated enones (2) that undergo a benzylic 1,4-rearrangement/cyclization reaction in the presence of base, yielding 2,5-dihydro-1,2-oxasiloles (3).
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PMID: 19125665
PDF is available here.
PDF is available here.
Abstract
Experiences with childhood hemolytic uremic syndrome (HUS) in Canada will focus on the development of the Canadian Pediatric Kidney Disease Research Centre (CPKDRC) and the results of our collaborative research over a 13-year period (1985-1998).
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PMID: 19180127
PDF is available here.
PDF is available here.
Abstract
Organocatalysts for the asymmetric reduction of ketimines are presented that function well at low catalyst loadings providing chiral amines in good yield and enantioselectivity, the latter appearing to be independent of the ketimine substrate geometry.
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PMID: 19109665
PDF is available here.
PDF is available here.
Carbohydrate Research (344)1 2009
Abstract
H(2)SO(4)-silica-promoted removal of benzylidene, isopropylidene, trityl and tert-butyldimethylsilyl groups from sugar derivatives was accomplished by following an 'on-column' protocol in a virtually waste-free condition.
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PMID: 18977476
PDF is available here.
PDF is available here.
Abstract
With an aim to develop a new approach to synthesize 4'-substituted nucleosides, reactions of thymidine derivatives having a benzenesulfonyl leaving group at the 4'-position with organosilicon and organoaluminum reagents were investigated. Two substrates 4alpha (alpha-L-isomer) and 4...
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PMID: 19749230
PDF is available here.
PDF is available here.
Abstract
We tried to disclose the detailed mechanism of such a discrimination ability of the silylated pyrene-modified DNA....
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PMID: 19749245
PDF is available here.
PDF is available here.
Abstract
Despite their rather recent invention, atomic force microscopes are widely available commercially. AFM and its special modifications (tapping mode and noncontact operation in solution) have been successfully used for topographic studies of a large number of biological objects including DNA, RNA, pro...
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PMID: 19378175
PDF is available here.
PDF is available here.
Abstract
Brooked up! Treatment of (R,Z)-3-(tert-butyldimethylsilyl)-1-cyano-3-hydroxyprop-1-enyl carbamate with a catalytic amount of a base afforded (S,E)-3-(tert-butyldimethylsilyloxy)-1-cyanoallyl diisopropylcarbamate, showing that S(E)2'-type reaction of allylsilicates proceeds in an anti fashion. The ov...
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PMID: 19222083
PDF is available here.
PDF is available here.
Abstract
The reaction conditions for the synthesis [Si(2)((Me)pz)(6)] (1) and [Si((Me)pz)(4)] (4) have been investigated in detail in order to obtain suitable precursor compounds for the synthesis of the hitherto unknown Janus-head ligand tris(3,5-dimethylpyrazolyl)silanide ([Si((Me)pz)(3)](-), (Me)Tpsd). Wi...
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PMID: 20449074
PDF is available here.
PDF is available here.
Abstract
(-)-Dysibetaine has been synthesized in 11 steps from readily available L-malic acid (see scheme). The key step is a unique Ugi 4-center-3-component cyclization reaction, where an ester group acts as the carboxylic acid component. The use of 1,1,1,3,3,3-hexamethyldisilazane as an ammonia equivalent...
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PMID: 19173271
PDF is available here.
PDF is available here.
Biosystems (94)3 2008
Abstract
Fluorescence spectroscopy methods are applied to the study of camptothecin analogue DB-67 and its ester DB-67-4ABTFA (trifluoroacetic acid salt of 20(S)-aminobutyrate substituted DB-67). Camptothecin and many of its analogues exhibit anticancer properties. They are fluorescent compounds, so using th...
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PMID: 18718502
PDF is available here.
PDF is available here.
Abstract
We report the multi-functionalized cubic silsesquioxane (POSS) as the ratiometric multimodal chemosensors for monitoring solvent polarity with fluorescence and (19)F NMR. The alteration of the dispersion state of the modified POSS by changing solvent polarity can be reflected into the orthogonal sig...
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PMID: 18954994
PDF is available here.
PDF is available here.
Abstract
A highly efficient kinetic resolution of racemic cis-4-(2-tert-butyldimethylsilyloxy-1,1-dimethyl)ethyl-3-tert-butyldimethylsilyloxy-azetidin-2-one with 7-O-triethylsilylbaccatin III was carried out to furnish 10-O-acetyl-5′-hydroxybutitaxel after removal of the silyl protecting groups. The compoun...
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PMID: 18977659
PDF is available here.
PDF is available here.
Lab On a Chip (8)12 2008
Abstract
We have, for the first time, demonstrated a simple fabrication process to form the hexamethyldisilazane (HMDS) and poly(ethylene glycol) (PEG) binary molecular surface which can be used to effectively form high fidelity cell arrays. The HMDS self-assembled monolayer (SAM) on glass substrates was pho...
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PMID: 19023473
PDF is available here.
PDF is available here.
Abstract
Silacarbonyl ylides, generated by metal-catalyzed silylene transfer to carbonyls, participate in formal intermolecular 1,3-dipolar cycloaddition reactions with carbonyl compounds and alkynes to form dioxasilacyclopentane acetals and oxasilacyclopentenes in an efficient, one-step process.
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PMID: 18922005
PDF is available here.
PDF is available here.
Journal of Organic Chemistry (73)22 2008
Abstract
A new synthesis of 3,3′-bioxindoles is reported that is well suited for the preparation of unsymmetrical structures. In the key step, 3-hydroxy-3,3′-bioxindoles are constructed by Mukaiyama aldol reaction of 2-siloxyindoles with isatins. These tertiary carbinols are formed in high diastereoselect...
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PMID: 18855482
PDF is available here.
PDF is available here.
Journal of Chromatography A (1211)1-2 2008
Abstract
This paper presents a derivatization, mass fragmentation study relating to the most common six cholic acids, such as cholic, lithocholic, chenodeoxycholic, ursodeoxycholic, 3-hydroxy,7-ketocholanic and dehydrocholic acids, identified and quantified as pollutants in the aquatic environment at the firs...
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PMID: 18849033
PDF is available here.
PDF is available here.
Abstract
A method for the preparation of inorganic superhydrophobic silica coatings using sol-gel processing with tetramethoxysilane and isobutyltrimethoxysilane as precursors is described. Incorporation of isobutyltrimethoxysilane into silica layers resulted in the existence of hydrophobic isobutyl surface...
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PMID: 18656893
PDF is available here.
PDF is available here.
Abstract
An alternative method for the preparation of polyhedral phenylsilsesquioxanes is reported. Phenylsilsesquioxane resin and freshly hydrolysed phenyltrimethoxysilane was refluxed with various phase-transfer catalysts and potassium fluoride in toluene yielding octaphenylsilsesquioxane, or in a mixture...
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PMID: 18802622
PDF is available here.
PDF is available here.
Abstract
Clearance of DB-67 lactone after administration of NL-DB-67 and L-DB-67 were 1.6 and 3.5 l/h/m(2), respectively; DB-67 lactone half-lives after administration of NL-DB-67 and L-DB-67 were 1.4 and 0.9 h, respectively. The percentages of DB-67 lactone in plasma after administration of NL-DB-67 and L-D...
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PMID: 18246299
PDF is available here.
PDF is available here.
Abstract
Our study, based on careful measurements of specular neutron reflectivity and grazing-incidence X-ray diffraction, showed that the blends with a low molecular-mass PalphaMS exhibited a strong segregation of TIPS-pentacene only at the air interface, but surprisingly the blends with a high molecular-m...
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PMID: 18722430
PDF is available here.
PDF is available here.
ChemPhysChem (9)13 2008
Abstract
An ester (PBPOSS) of 1-pyrenebutyric acid (PBA) and 1-(2,3-propanediol)propoxy-3,5,7,9,11,13,15-isobutylpentacyclo-[9.5.1.1(3,9).1(5,15).1(7,13)]octasiloxane (a polyhedral oligomeric silsesquioxane, POSS) is synthesized by simple one-step esterification. Thin films of PBPOSS fabricated by the spin-c...
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PMID: 18756555
PDF is available here.
PDF is available here.
Abstract
Novel amine- and ammonium-terminated carbosilane dendrimers of type G(n)-[Si{CH(2)O-(C(6)H(4))-3-NMe(2)}](x) or G(n)-[Si{CH(2)O-(C(6)H(4))-3-NMe(3)(+)I(-)}](x) have been synthesized and characterized up to second generation by phenolysis of (chloromethyl)silyl-terminated dendrimers with 3-dimethylam...
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PMID: 18802631
PDF is available here.
PDF is available here.
Chemical Reviews (108)9 2008
Abstract
Abstract
A new hybrid thermoplastic polyurethane (TPU) system that incorporates an organic, biodegradable poly(D, L-lactide) soft block with a hard block bearing the inorganic polyhedral oligosilsesquioxane (POSS) moiety is introduced and studied. Changes in the polyol composition made through variation of t...
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PMID: 18698847
PDF is available here.
PDF is available here.
Abstract
Trisiloxane surfactants are widely used in pesticide applications as adjuvants to promote spray drop spreading on leaves. The efficacy of the spray is related to the wetting of plant surfaces. The surface (composite or wetted) formed by the liquid drop instantly contacting with the substrate is vita...
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PMID: 18571664
PDF is available here.
PDF is available here.
Abstract
Conditions for a site-selective ceric ammonium nitrate oxidation have been developed. The reactions proceed nicely on both 1K- and 12K-microelectrode arrays. The procedure for developing the reactions was very simple and demonstrated that the same reagents used for a solution-phase reaction can be u...
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PMID: 18680369
PDF is available here.
PDF is available here.
Analytica Chimica Acta (624)2 2008
Abstract
The solid phase microextraction (SPME) technique with on-fiber derivatization was evaluated for the analysis of alkylphenols (APs), including 4-tert-octylphenol (4-t-OP), technical nonylphenol isomers (t-NPs) and 4-nonylphenol (4-NP), in water. The 85 microm polyacrylate (PA) fiber was used and a tw...
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PMID: 18706331
PDF is available here.
PDF is available here.
Abstract
By making use of the aggregation-induced emission feature of silole, compound 1 with an ammonium group is designed and synthesized with a view to developing a new optical probe for fluorescence turn-on detection of DNA and label-free fluorescence nuclease assay. The fluorescence of 1 increases large...
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PMID: 18576669
PDF is available here.
PDF is available here.
Abstract
Here we report the synthesis of a novel electrochemically active polymer, preparation of adlayers of the polymer on optically transparent electrodes, and an application of the adlayers to immobilization of engineered cells through a direct covalent coupling reaction.
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PMID: 18654707
PDF is available here.
PDF is available here.
Abstract