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Otorhinolaryngologic Neoplasms (4):
Recent article
Otorhinolaryngologic Neoplasms
Abstract
We have designed and evaluated a new, nearly automatic and operator-independent segmentation approach. This incorporated possibility theory, in order to take into account the uncertainty and inaccuracy inherent in the image. The approach remained independent of PET facilities since it did not requir...
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PMID: 20952337
PDF is available here.
PDF is available here.
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Bulletin du cancer (97)12 2010
Abstract
Abstract
The fibula osteoseptocutaneous flap is an excellent option for the reconstruction of segmental mandibular defects. This study was conducted to investigate the relationship between ischemia time and outcome of the fibula flap, thus establishing the critical ischemia time for this procedure.
Between F...
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PMID: 21124137
PDF is available here.
PDF is available here.
Abstract
Various interdisciplinary guidelines recommend that in-patients at risk of venous thromboembolism should receive pharmacologic prophylaxis. Among the anticoagulants low-molecular-weight heparins (LMWH) and fondaparinux can be considered the medications of choice because of the favorable pharmacokine...
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PMID: 20694545
PDF is available here.
PDF is available here.
Abstract
Recurrent disease is one of the main reasons for the persistently poor prognosis of squamous cell carcinoma of the head and neck (HNSCC; European 5-year survival, 42%). The main treatment option for primary and secondary malignancy as well as recurrent disease is surgical therapy. If R0 resection (r...
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PMID: 20628714
PDF is available here.
PDF is available here.
Laryngo-Rhino-Otologie (89)7 2010
Abstract
Organ preservation protocols for advanced head and neck carcinoma have proven to be successful in controlled clinical trials. This has led to an increase in the use of primary chemoradiation for these tumors. However, the intensification of nonoperative treatment protocols has been associated with a...
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PMID: 20617480
PDF is available here.
PDF is available here.
Cancer/Radiothérapie (14)3 2010
Abstract
Control charts, showing drifts, both slow and weak, and also both strong and fast, of mean and standard deviation have been established and have shown special cause introduced (manual shift of the leaf gap of the multileaf collimator). Correlation between dose measured at one point, given with the E...
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PMID: 20434386
PDF is available here.
PDF is available here.
Wiener Medizinische Wochenschrift (160)11-12 2010
Abstract
High-risk types of human papillomaviruses (HR HPV) play an important role in the etiology of a group of head and neck squamous cell cancers (HNSCC). This review is focused on epidemiological, molecular, and clinical aspects of HPV infection in head and neck cancer. High risk HPV DNA is being detecte...
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PMID: 20640929
PDF is available here.
PDF is available here.
Abstract
The use of MLC-5 led to a significantly higher conformity index and an improvement of the 90% coverage of PTV1 (planning target volume) and PTV2 compared with MLC-10. This was noted in the nine- and seven-beam plans. Within the nine-beam group with MLC-5, a reduction of the segment number by up to 2...
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PMID: 20495969
PDF is available here.
PDF is available here.
Abstract
Traditional diagnostic methods such as clinical assessment, histopathological examination and imaging techniques are limited in their capacity to provide information on prognosis and treatment choice of head and neck cancer. In recent years, molecular techniques have been developed that enabled us t...
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PMID: 20037788
PDF is available here.
PDF is available here.
Abstract
Laryngo-Rhino-Otologie (89)5 2010
Abstract
Abstract
The hybrid technique of PET/CT has significantly impacted the imaging and management of HNSCC since its introduction in 2001 and has become the technique of choice for imaging of this cancer. Diagnostic FDG-PET/CT is useful for identification of an unknown primary tumor, delineation...
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PMID: 19910448
PDF is available here.
PDF is available here.
Abstract
We present a case series of 13 patients with imaging findings highly suggestive of hyoid ORN after radiation therapy for head and neck cancers, in which we observed progressive features of hyoid disruption along with adjacent soft-tissue ulceration.
Pretreatment imaging, when availab...
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PMID: 19942694
PDF is available here.
PDF is available here.
Abstract
Does the K-means algorithm do a better job of differentiating benign and malignant neck pathologies compared to only mean ADC? The objective of our study was to analyze the differences between ADC partitions to evaluate whether the K-means technique can be of additional benefit to wh...
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PMID: 20007723
PDF is available here.
PDF is available here.
Abstract
Water in biological structures often displays non-Gaussian diffusion behavior. The objective of this study was to test the feasibility of non-Gaussian fitting by using the kurtosis model of the signal intensity decay curves obtained from DWI by using an extended range of b-values in...
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PMID: 20037133
PDF is available here.
PDF is available here.
Abstract
We present a review of its mechanism of action, indications, side effects and economic issues, accompanied by a clinical example from our institution....
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PMID: 20167650
PDF is available here.
PDF is available here.
Laryngo-Rhino-Otologie (89)2 2010
Abstract
Perioperative immunonutrition is aiming at modulating altered immunological and metabolic functions in the context of major surgery. It is defined as the supplementation of constitutionally essential substrates such as glutamine, arginine, omega-3-fatty acids or nucleotides. The application of such...
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PMID: 20155649
PDF is available here.
PDF is available here.
Abstract
This study included 80 patients having oncological problems in whom defects resulting from the removal of affected tissues were closed using one-step or delayed reconstruction with a m. pectoralis major flap having axial blood supply The patients of different groups were matched for the main clinica...
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PMID: 20436428
PDF is available here.
PDF is available here.
Laryngo-Rhino-Otologie (89)1 2010
Abstract
Human papilloma viruses (HPV) may cause head and neck squamous cell carcinomas. HPV associated carcinomas mostly occur in the oropharynx and particularly in the palatine tonsil and base of tongue. Carcinomas at other sites are infrequently caused by HPV. The viral proteins E6 and E7 are crucial for...
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PMID: 20058217
PDF is available here.
PDF is available here.
Acta Oto-Laryngologica (129)11 2009
Abstract
The prevalence of sleep apnoea among patients following treatment of head and neck carcinomas seems to be slightly higher than in the normal population. The possible importance of tumour treatment features, especially transient tracheostoma, needs further assessment. OBJECTIVES: The epidemiology of...
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PMID: 19863328
PDF is available here.
PDF is available here.
Acta Oto-Laryngologica (129)11 2009
Abstract
In analyzing exons 18-21 of EGFR in 96 patients with SCCHN, only one SNP was found in the 78th site of exon 20 and it mostly existed in specimens coming from the hypopharynx. Further statistical analysis showed that among the clinical or histopathologic parameters, the 78th SNP had a close relations...
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PMID: 19863329
PDF is available here.
PDF is available here.
Ear, Nose and Throat Journal (88)10 2009
Abstract
We report a rare case of an intrathyroidal fourth branchial pouch sinus in an adult. A 36-year-old man presented with a recurrent left-sided deep neck abscess. A diagnostic evaluation by barium pharyngoesophagography in conjunction with computed tomography revealed the presence of a sinus tract that...
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PMID: 19826988
PDF is available here.
PDF is available here.
Bulletin du cancer (96)9 2009
Abstract
Image-guided frameless fractionated stereotactic radiotherapy can be performed with millimetric accuracy using the CyberKnife (Accuray Inc. Sunnyvale, USA) equipped with an integrated tracking system for intra- and extracranial lesions. Highly conformal hypofractionated irradiation has been used to...
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PMID: 19736172
PDF is available here.
PDF is available here.
Abstract
This bibliography is compiled by clinicians from the journals listed at the end of this publication. It is based on literature entered into our database between 1 February 2008 and 31 January 2009 (articles are generally added to the database about two and a half months after publication). In additi...
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PMID: 19454893
PDF is available here.
PDF is available here.
Abstract
Specific oropharyngeal swallowing motility disorders after chemoradiotherapy have been identified. Damage to specific structures has been correlated with specific pharyngeal phase swallow impairment. Swallowing function and quality of life have been examined over time, with improvement seen in both....
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PMID: 19337126
PDF is available here.
PDF is available here.
Laryngoscope (119)6 2009
Abstract
We sought to test similar hypotheses that neck dissection is a volume-sensitive procedure wherein the number of lymph nodes harvested and clinical outcomes are correlated with the number of neck dissections performed.
We conducted a retrospective analysis of 375 neck dissections. The number of nodes...
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PMID: 19296506
PDF is available here.
PDF is available here.
Laryngo-Rhino-Otologie (88)5 2009
Abstract
The present work discusses soft tissue sarcoma in the head and neck area, due to the rare occurrence and the sparse data situation is still a large number of unexplained riddles. The head and neck surgeon plays the central role in the diagnosis and treatment of the vast majority of soft tissue sarco...
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PMID: 19391071
PDF is available here.
PDF is available here.
Bulletin du cancer (96)4 2009
Abstract
The head-and-neck squamous-cell carcinomas (HNSCC) represent in order of frequency the fourth leading cause of cancer deaths among men in France. The term HNSCC includes various anatomopathological and clinical entities with different evolution patterns. For this reason, it is necessary to identify...
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PMID: 19357012
PDF is available here.
PDF is available here.
Laryngo-Rhino-Otologie (88)2 2009
Abstract
The interdisciplinary consensus reached by the experts is not intended to recommend standard guidelines in the management of head and neck cancer but to summarise and stress the impact of FDG PET/CT on the basis of the present literature and current clinical practise....
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PMID: 19219754
PDF is available here.
PDF is available here.
Laryngo-Rhino-Otologie (88)2 2009
Abstract
The dental care in case of head and neck cancer resection should be accomplished by skilled dentists with focus in prosthetics in cooperation with special skilled dental technicians and a specialist in epithetics. The patient must be introduced to the dentist before operation. Otherwise reconstructi...
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PMID: 19219757
PDF is available here.
PDF is available here.
Abstract
Numerical and structural centrosome abnormalities play a critical role in the tumor progression of in head and neck squamous cell carcinoma (HNSCC) and may provide useful information as a prognostic factor for these patients. OBJECTIVES: Centrosome alterations are often linked with aneuploidy, cell...
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PMID: 18607971
PDF is available here.
PDF is available here.
Acta Oto-Laryngologica (129)11 2009
Abstract
Weekly paclitaxel may be an active and well tolerated chemotherapy regimen for patients with platin-resistant advanced head and neck cancer. OBJECTIVES: Weekly paclitaxel should be an active and well tolerated regimen for palliative treatment of platin-resistant patients with recurrent or metastatic...
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PMID: 19863327
PDF is available here.
PDF is available here.
Bulletin du cancer (96)1 2009
Abstract
The objective of Image-Guided Radiotherapy (IGRT) is to take in account the inter- or/and intrafraction anatomic variations (organ motion and deformations) in order to improve treatment accuracy. The IGRT should therefore translate in a clinical benefit the recent advances in both tumor definition t...
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PMID: 19211367
PDF is available here.
PDF is available here.
Abstract
The article aims to understand the coping strategies of postsurgery head and neck cancer patients in Mumbai, India. A descriptive research design with a sample of 80 patients suffering from head and neck cancer was selected to analyze their coping strategies in relation to sociodemographic profile a...
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PMID: 19544181
PDF is available here.
PDF is available here.
Laryngoscope (118)12 2008
Abstract
One hundred thirty-four consecutive patients underwent a total of 137 microvascular FTTs using a coupling device. In our series, a total of 173 end-to-side anastomoses were completed in 96 patients. Of these, 77 patients had both venous anastomoses, 17 underwent one end-to-side and one end-to-end an...
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PMID: 19029861
PDF is available here.
PDF is available here.
Laryngoscope (118)12 2008
Abstract
All patients had en bloc resection of the tumor together with internal carotid artery and reconstruction with ePTFE. Some patients required wound coverage with myocutaneous flaps in eight patients and local flaps in five patients. Intraoperative shunting was used in all patients. Intraoperative hepa...
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PMID: 18797418
PDF is available here.
PDF is available here.
Abstract
These results support previous opinions that the gastric pull-up procedure has good swallowing outcomes, and indicate that such outcomes continue in the long term....
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PMID: 18485250
PDF is available here.
PDF is available here.
Laryngo-Rhino-Otologie (87)12 2008
Abstract
Laryngo-Rhino-Otologie (87)12 2008
Abstract
The dental care because of radiotherapy in case of head and neck cancer should be practiced by skilled dentists. First the residual teeth and the dental restorations have to be cleaned and controlled very well. Radiographs complete examinations. Necessary extractions should consider the later prosth...
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PMID: 19031347
PDF is available here.
PDF is available here.
Abstract
We selected and genotyped one SNP from each of the three previously determined "regions" within the 8q24 loci, rs1447295 (region 1), rs16901979 (region 2), and rs6983267 (region 3), and examined their association with cancers of the lung, oropharynx, nasopharynx, larynx, esophagus, stomach, liver, b...
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PMID: 18990762
PDF is available here.
PDF is available here.
Bulletin du cancer (95)11 2008
Abstract
Abstract
Tumor growth positively correlated and animal survival negatively correlated with increasing EMMPRIN expression. FaDu/E tumor growth was significantly larger at 4 weeks compared with FaDu tumors (P = .006). Similarly, the control vector-transfected FaDu tumors were significantly larger than FaDu/siE...
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PMID: 19015455
PDF is available here.
PDF is available here.
Auris Nasus Larynx (35)3 2008
Abstract
At the point of time T7 we observed a reduction of the tumour growth rate, of the proliferative activity and of the VEGF- as well as of the VEGF-R-expression. At the point of time T70 we found increased values for proliferation, microvessel density, VEGF- and flk-1 expression in the therapy group co...
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PMID: 17980533
PDF is available here.
PDF is available here.
Acta Oto-Laryngologica (128)8 2008
Abstract
The negative predictive value (NPV) of sentinel lymph node biopsy (SNB) in this study was 95%. The accuracy of SNB compared to histopathologic evaluation of surgical specimen of subsequent neck dissection (ND) was 96%. OBJECTIVE: To evaluate NPV of SNB in head and neck cancer. PATIENTS AND METHODS:...
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PMID: 18607941
PDF is available here.
PDF is available here.
Abstract
For high-risk basal cell and squamous cell carcinomas, studies continue to report superior cure rates with Mohs surgery compared with non-Mohs modalities such as standard surgical excision. Despite several supporting studies, Mohs surgery for melanoma continues to be controversial in the literature,...
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PMID: 18626258
PDF is available here.
PDF is available here.
Abstract
The current literature supports the use of anastomotic coupling devices in head and neck reconstructive surgery. They have been reported as consistently reducing the anastomotic time with an associated reduction in cold ischaemic time. There is no evidence available to date that shows different thro...
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PMID: 18626251
PDF is available here.
PDF is available here.
Abstract
Fibrin glues have been used extensively in head and neck procedures. Fibrin glues have been successfully used to reduce wound drainage and to improve other short-term postoperative results. More recently, commercial systems have become available that allow easy and rapid isolation of autologous tiss...
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PMID: 18626248
PDF is available here.
PDF is available here.
Abstract
Protocol patients demonstrated significantly fewer AWS-related ICU transfers and less delirium and violence than preprotocol patients. Mortality, wound complications, hospital charges, and doses of benzodiazepines, clonidine, and haloperidol were not significantly different between these 2 groups. P...
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PMID: 18711062
PDF is available here.
PDF is available here.
Abstract
The mean (+/- SD) SUV(mean), SUV(max), BF, BV, MTT, and PS values in the tumor tissue were 6.26 (+/- 1.48), 15.25 (+/- 3.81), 91.50 (+/- 24.69), 5.08 (+/- 1.17), 7.51 (+/- 2.24), and 23.08 (+/- 8.77), respectively. All PET/CT and PCT parameters of muscle versus tumor tissue were statistically differ...
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PMID: 18483187
PDF is available here.
PDF is available here.
Abstract
Nodal size, shaggy margin, and flare sign criteria were independent and significant MR imaging findings suggestive of extranodal spread in the metastatic nodes. We obtained 77% sensitivity and 93% specificity with the flare sign, 65% sensitivity and 99% specificity with the shaggy margin, and 80% se...
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PMID: 18403554
PDF is available here.
PDF is available here.
Abstract
Bivariate analysis showed a significant correlation of HIF-1alpha expression with high P53 and high OPN expression, high serum VEGF Levels, and low VHL and low Ki67 expression. The CAIX expression was inversely correlated with pH value and directly correlated with T-stage. However, no correlation wa...
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PMID: 18956515
PDF is available here.
PDF is available here.
Abstract
A total of 690 samples were analyzed in 224 patients. The mean selenium value was 75.64 microg/l at the beginning of radiotherapy. 170 patients (77%) had reduced selenium Levels < 89 microg/l. Twelve patients (5.4%), mostly with head-and-neck cancer, had critically low values which need to be contro...
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PMID: 18956518
PDF is available here.
PDF is available here.
Abstract
There was a significant dose-response relationship between mean parotid dose and functional recuperation. If the mean dose was kept <31 Gy, a recuperation of 75% can be expected at 12 months. The authors equally observed a significant correlation between salivary excretion (SE) and the percentage of...
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PMID: 18956516
PDF is available here.
PDF is available here.
Laryngoscope (118)7 2008
Abstract
Chondrosarcoma of the hyoid bone is a rare disease of which only 14 cases have been reported until now. Patients with this disease have no sexual or racial preponderance, and most presented with a mass in the upper neck which has splotchy calcification in radiologic imaging without enhancement. The...
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PMID: 18475210
PDF is available here.
PDF is available here.
Laryngoscope (118)7 2008
Abstract
There is a high incidence of occult metastases in clinically node-negative patients which adversely affects survival, regardless of the use of adjuvant XRT. Postoperative XRT did not significantly affect regional control or survival rates in patients with <3 positive nodes. When ECS was present, sur...
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PMID: 18391764
PDF is available here.
PDF is available here.
Effect of docetaxel on the surgical tumor microenvironment of head and neck cancer in murine models.
Abstract
These preclinical results support further testing of IW docetaxel treatment in HNSCC. Docetaxel appears to exert antitumor activity without affecting factors involved in wound healing in the tumor microenvironment....
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PMID: 18645124
PDF is available here.
PDF is available here.
Abstract
This is the largest reported series, to our knowledge, of implantable Cook-Swartz Doppler use, and our experience would suggest that this is a reliable technique for postoperative monitoring in head and neck reconstruction. Our use of the implantable Doppler probe allowed us to recognize vascular co...
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PMID: 18645123
PDF is available here.
PDF is available here.
Laryngo-Rhino-Otologie (87)7 2008
Abstract
The aggressive character of the SS as well as its high recurrence rate afford a radical therapeutic scheme enclosing surgical, chemotherapeutical and radiological treatment as well as a thorough follow-up. The genetic translocation t(X;18) leads the way to the right diagnosis. The prognosis of head...
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PMID: 18231962
PDF is available here.
PDF is available here.