Abstract
Ion channels in cell membranes are targets for a multitude of ligands including naturally occurring toxins, illicit drugs, and medications used to manage pain and treat cardiovascular, neurological, autoimmune, and other health disorders. In the past decade, the x-ray crystallography...
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PMID: 21961291
PDF is available here.
Abstract
The published literature that addresses the many facets of pharmaceutical ingredients as environmental contaminants has grown exponentially since the 1990s. Although there are several thousand active ingredients used in medical pharmaceuticals worldwide, illicit drug ingredients (IDIs) have generall...
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PMID: 21170703
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Abstract
This study investigated human immunodeficiency virus (HIV) testing and risk behaviors in a longitudinal sample of young men who have sex with men (YMSM).
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PMID: 21361809
PDF is available here.
Abstract
Saccharin avoidance conditioned by drugs of abuse (CSA) has been interpreted as an expression of the appetitive, dopamine-dependent, properties of the drug. Repeated exposure to these drugs induces an increase (sensitization) of their motor stimulant properties associated with differential changes i...
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PMID: 20561960
PDF is available here.
Abstract
Many psychotropic substances are illegally available on the streets and/or via the Internet. This wide distribution has become a serious social problem. To control this problem, many substances have been controlled as 'designated substances' (Shitei-Yakubutsu) in Japan since April 2007 by the Pharma...
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PMID: 21077248
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Abstract
We have assessed the prevalence and predictor factors for driving after alcohol and drug use by adolescents.
A cross-sectional survey involving 11,239 students aged 14-18 years from 252 private and public schools in the Valencia region of Spain was conducted. The prevalence and predictors of driving...
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PMID: 20728658
PDF is available here.
Abstract
The current study set to examine whether there are inter-generational and gender-based differences between family members self-assessing their ability to drive under normal conditions and while under the influence of either alcohol or drugs. Participants were 135 young-adults and both their parents,...
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PMID: 20728671
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Abstract
We selected 10,002 drivers involved in a traffic accident or violation between 2007 and 2008 in Shanghai, Suzhou and Wuxi. We checked for the presence of psychoactive drugs from blood samples using liquid chromatography tandem mass spectrometry (LC-MS-MS). Of the 10,002 drivers, 10.5% tested positiv...
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PMID: 20728679
PDF is available here.
Abstract
The ADVANCED QUALITY One Step Multi-Drug Screen test is a new urine on-site immunoassay test that is designed to detect multiple drugs of abuse in one time (barbiturates, benzodiazepines, cocaine, methylenedioxymethamphetamine (MDMA), methamphetamine, and opiates group). Thus, the present research w...
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PMID: 21114210
PDF is available here.
Abstract
Young people have long been confronted with choices about whether to use alcohol and other drugs. Today, however, they are having to make those decisions at a younger age, and they are encountering substances that were unheard of by members of their parents' generation. This article describes trends...
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PMID: 20957927
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Abstract
Since government and private industry have instituted urine drug testing to ensure a drug-free work force, an industry dedicated to subverting the results of those tests has developed. This article describes that industry, the types of products it markets, and efforts to curb the sale of those produ...
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PMID: 20862879
PDF is available here.
Abstract
Cannabis is the most widely consumed illicit drug in the western world. Cannabis and tobacco smoke contain a similar mix of irritant and toxic chemicals. Therefore, there are reasons to suspect, that cannabis and tobacco have similar side effects. However, the pulmonary effects of smoking cannabis h...
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PMID: 20687046
PDF is available here.
Abstract
The authors systematically reviewed 42 quantitative studies on the relationship between media exposure and tobacco, illicit drug, and alcohol use among children and adolescents. Overall, 83% of studies reported that media was associated with increased risk of smoking initiation, use of illicit drugs...
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PMID: 20687006
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Abstract
The results of a logistic regression analysis indicated a significant association between past-year alcohol consumption and the likelihood of past-year smoking initiation after controlling for respondent race, the past-year use of marijuana, illicit drug use, and prescription drug use. CONCLUSIONS A...
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PMID: 20560839
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Abstract
The types of drugs used by pregnant drug users follow street trends and may affect infant hospitalisation and withdrawal treatment. Of concern is the rise in amphetamine-use and there needs to be increased vigilance for similar trends, especially in previously unidentified drug users....
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PMID: 20618239
PDF is available here.
Abstract
Doping is a phenomenon which in the past years through the various incidences in professional cycling has come more and more into the focus of the public interest. Whilst in the young past the problems were to define the term "doping" exactly, today's problem is to prevent adolescents and children o...
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PMID: 20552290
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Abstract
We carried out a sequential mixed method approach with a sample of 501 health professionals in training or practice from the disciplines of medicine, nursing, psychology and social work. Results evidence the continued existence of stigmatizing attitudes among this population. We discuss some of the...
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PMID: 20496525
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Abstract
Urban frontline services have recorded increases in psychostimulant-related presentations. A convenience sample of 183 street-based psychostimulant injectors recruited in April 2006 was administered the Kessler Psychological Distress Scale (K10) to assess psychological distress. Homelessness, unempl...
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PMID: 20441457
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Abstract
The group who had been diagnosed with a depressive episode, F32 , were less likely to be discharged and appeared to be more likely to suffer from alcoholism, illicit drug abuse, and suicidality. DISCUSSION: Arguably, the F32 group could be a more heterogeneous group of patients, F32 becoming a 'defa...
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PMID: 20562791
PDF is available here.
Abstract
We examined the way recent experiences of a diverse set of stressors predict illicit drug use, alcohol misuse, and inconsistent condom use (i.e., unprotected anal intercourse) among an ethnically diverse cohort of YMSM (N=526). Results indicated that stress related to financial and health concerns w...
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PMID: 19608264
PDF is available here.
Abstract
We used data from a school-based study of 496 adolescent girls to identify qualitatively distinct substance use and substance abuse developmental trajectory groups and tested whether the problematic groups differed from the non-problematic groups on baseline and outcome validation variables. Results...
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PMID: 19640578
PDF is available here.
Abstract
Both music preferences and the substance use behavior of peers are important elements in explaining adolescent substance use. The extent to which music preference and peer use overlap in explaining adolescent substance use remains to be determined. A nationally representative sample of 7324 Dutch sc...
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PMID: 19818488
PDF is available here.
Abstract
Of the 285 AXRs performed 59 were positive, 221 negative and five were indeterminate. The tic-tac sign was present in 93%, double condom sign in 73%, dense surrounding wrapping material in 36% and parallelism in 27%. Sixty one percentage of drug packages were iso-dense to faeces and 39% hyperdense....
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PMID: 20382355
PDF is available here.
Abstract
Alcohol use continues to be a major problem from preadolescence through young adulthood in the United States. Results of recent neuroscience research have substantiated the deleterious effects of alcohol on adolescent brain development and added even more evidence to support the call to prevent and...
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PMID: 20385640
PDF is available here.
Abstract
Low temperature plasma (LTP) ionization is an ambient plasma ionization method that permits the direct mass analysis of samples in their native atmospheric environment with little or no sample preparation. In this work, the low temperature plasma probe is used in the direct and rapid mass spectromet...
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PMID: 20419240
PDF is available here.
Abstract
CEBRID (Brazilian Center of Information on Psychotropic Drugs) conducted two household surveys on drug use in Brazil, the first in 2001 and the second in 2005, making it possible for researchers, for the first time ever, to have a timeline comparison using this type of methodology. The universe stud...
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PMID: 20464178
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Abstract
The objective of this article is to: (1) evaluate the rationality and opportunity of this debate; (2) try to establish links with legal drugs; (3) evaluate the available data on the effect of legalization of a drug; and (4) propose an alternative drug police based on clear objectives to be reached;...
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PMID: 20464172
PDF is available here.
Abstract
The drug addiction process shares many commonalities with normal learning and memory. Addictive drugs subvert normal synaptic plasticity mechanisms, and the consequent synaptic changes underlie long-lasting modifications in behavior that accrue during the progression from drug use to addiction. Supp...
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PMID: 20445070
PDF is available here.
Abstract
We conducted a study to examine the extent of the usage of Mephedrone, Methylone and BZP amongst attendees of Methadone maintenance programs at the DTCB. Two hundred and nine samples in total were tested. The results showed significant usage of these compounds amongst this cohort of drug users, with...
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PMID: 20666082
PDF is available here.
Abstract
We report the case of a 32-year old man, dying suddenly and unexpectedly after a well-known history of drug abuse for more than a decade. The granulomas are caused by foreign particle embolization immediately after intravenous injection of not only the drug itself but also of adulterants, e.g. cotto...
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PMID: 20137873
PDF is available here.
Abstract
Alcoholism is a severely stigmatized condition. In order to change the stigma of alcoholism, studies exploring theoretical models and mechanisms of stigmatization seem necessary.
Copyright Georg Thieme Verlag KG Stuttgart . New York....
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PMID: 20148378
PDF is available here.
Abstract
We conclude that the SMAST-13 and DAST-20 in combination with the AUS and DUS, which are easy and quick to perform, are helpful in establishing a common understanding of the patient's alcohol and drug problems in an early intervention clinic....
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PMID: 19883188
PDF is available here.
Abstract
This study characterizes the prevalence of drug use among Filipino street children compared with Filipino non-street children. A cross-sectional survey was administered to 311 street children and 528 non-street children aged 13 to 17 years. Participants were enrolled through 4 nonprofit organization...
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PMID: 20457649
PDF is available here.
Abstract
Roadside studies indicate that 1-15% of drivers drive under the influence of one or more drugs of abuse. After drug use, drivers are more often culpable for an accident than non-users. Information on drugs and traffic safety comes from roadside studies, epidemiological research, experimental studies...
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PMID: 20088818
PDF is available here.
Abstract
A baseline assessment for an HIV health services study recruited 626 people living with HIV/AIDS (PLWHA) in New York city who participated in an interview querying social support, health status, substance use, and mental health. Data were modeled using hierarchical classes (HICLAS) analysis. HICLAS...
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PMID: 20391231
PDF is available here.
Abstract
This study assessed substance abuse treatment providers' beliefs about empirically supported treatments (ESTs) to determine if providing information about empirical support for interventions would change beliefs. Treatment providers (N=136) completed an interview regarding five interventions with va...
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PMID: 19959299
PDF is available here.
Abstract
One such agent whose epidemiologic characteristics parallel those of gastroschisis is Epstein-Barr virus (EBV). Primary EBV infection in early childhood has been decreasing over time, leaving a greater proportion of adolescents at risk, as reflected by increased rates of infectious mononucleosis ove...
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PMID: 19937602
PDF is available here.
Abstract
The usage of Ecstasy and related drug (ERD) has increasingly been the focus of epidemiological and other public health-related research. One of the more promising methods is the use of the Internet as a recruitment and survey tool. However, there remain methodological concerns and questions about re...
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PMID: 20141457
PDF is available here.
Abstract
Dependence on illicit drugs during pregnancy is a major public health concern as there may be associated adverse maternal, fetal, and neonatal consequences. Sweat patches (n = 389) were collected from 39 pregnant volunteers who provided written informed consent for this Institutional Review Board-ap...
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PMID: 19927046
PDF is available here.
Abstract
"Labelled drug-related public expenditure" is the direct expenditure explicitly labelled as related to illicit drugs by the general government of the state. As part of the reporting exercise corresponding to 2005, the European Monitoring Centre for Drugs and Drug Addiction's network of national foca...
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PMID: 20478069
PDF is available here.
Abstract
Our objective in this study was to examine the prevalence and correlates of intentional fire-setting behavior in the United States. Data were derived from a nationally representative sample of US residents 18 years and older. Structured psychiatric interviews (N = 43,093) were completed by trained l...
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PMID: 20399330
PDF is available here.