Abstract
We are able to support the conservation of native forest resources of medicinal use by means of vegetative propagation techniques....
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PMID: 21834239
PDF is available here.
Abstract
Anti-ulcer potential and proton pump inhibitory activity of kolaviron (KV) isolated from Garcinia kola Heckel has been evaluated using different ulcer models. Cold-restraint (CRU), aspirin (ASP), alcohol (AL), pyloric ligation (PL) induced gastric ulcer models were used to assess anti-ulcerogenic act...
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PMID: 21702226
PDF is available here.
Abstract
We specifically deal with biosynthesis of podophyllotoxin with an emphasis on the literatures of the past decade, highlighting characterization of genes encoding synthetic enzymes and down-stream metabolism of PTOX. The present review focuses on several key biosynthesis processes, important metaboli...
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PMID: 21842631
PDF is available here.
Abstract
The paper aims to specify all important active principles in the herb Genista tinctoria which exert different biological activities. It also mentions the methods of chemical evaluation of these substances.
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PMID: 21650007
PDF is available here.
Jong Bae JB Seo,
Sung Sik SS Choe,
Hyun Woo HW Jeong,
Sang Wook SW Park,
Hyun Jung HJ Shin,
Sun Mi SM Choi,
Jae Young JY Park,
Eun Wook EW Choi,
Jae Bum JB Kim,
Dong Seung DS Seen,
Jae-Yeon JY Jeong and
Tae Gyu TG Lee
Abstract
We performed various obesity-related experiments in vitro and in vivo. In adipogenesis assay, LFE blocked the differentiation of 3T3-L1 preadipocyte in a dose-dependent manner with an IC50 of 2.5 μg/ml. In addition, LFE suppressed the expression of lipogenic genes, while increasing the expression o...
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PMID: 21389766
PDF is available here.
Abstract
Plant-derived medicines have a long history of use for the prevention and treatment of human disease. Today, many pharmaceuticals currently approved by the Food and Drug Administration (FDA) have origins to plant sources. A major role for plant-derived compounds based on the reported...
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PMID: 21056709
PDF is available here.
Abstract
Malaria is a major public health problem in many tropical and subtropical countries and the burden of this disease is getting worse, mainly due to the increasing resistance of Plasmodium falciparum against the widely available antimalarial drugs. There is an urgent need for discovery...
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PMID: 21095187
PDF is available here.
Abstract
To evaluate herbal medicines, other than St. John's wort, in the treatment of depression. DATA SOURCES/SEARCH METHODS: A computer-based search of Medline, Cinahl, AMED, ALT Health Watch, Psych Articles, Psych Info, Current Contents databases, Cochrane Controlled Trials Register, and Cochrane Database...
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PMID: 21438645
PDF is available here.
Abstract
We studied the interaction of [6]-gingerol, [8]-gingerol, [10]-gingerol (racemates), and [6]-shogaol with guinea pig M (3) receptors, guinea pig 5-HT (3) receptors, and rat 5-HT (4) receptors. In whole segments of guinea pig ileum (bioassay for contractile M (3) receptors), [6]-gingerol, [8]-gingero...
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PMID: 21305447
PDF is available here.
Abstract
These results suggest that TCE is a potential agent for alleviating diabetic complications....
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PMID: 21308613
PDF is available here.
Abstract
A dispensary register from 1725 and contemporaneous container subscriptions allows an approach of 18th century pharmacopea different from the treatises' in a Catalonian farmacy. The drugs panel shows comparisons with regional scheme and the role of local flora. The prescription register--exceptional...
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PMID: 21661223
PDF is available here.
Abstract
We also analyzed its effect on cell proliferation IN VITRO, cytotoxicity, and skin irritation. Different extracts obtained from the aerial parts of A. pichinchensis, topically administrated, were evaluated in a healing model by scalpel-blade incision on the rat. The extracts, at 10 % concentrations,...
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PMID: 21267810
PDF is available here.
Abstract
The pathogenicity of staphylococcus aureus is dependent largely upon its ability to secrete a number of virulence factors, therefore, anti-virulence strategy to combat S. aureus-mediated infections is now gaining great interest. It is widely recognized that some plant essential oils could affect the...
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PMID: 21283822
PDF is available here.
Abstract
Dieting plays a central role in healing among Iquito speakers. Specific prohibitions can be explained in terms of specific aspects of illness etiologies, pathophysiologies and treatments. Although the Amazonian literature contains few studies focusing on dietary proscriptions over a wide range of il...
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PMID: 21745400
PDF is available here.
Abstract
Growing interest is on food tree species in general, and particularly indigenous fruit tree species in developing countries since they are inherent to most tropical landscapes and serve the dual function of local livelihood support and biodiversity conservation. It is therefore relevant to assess the...
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PMID: 21284847
PDF is available here.
Abstract
Menzies made the earliest extant botanical collections in the Galápagos; five sheets, representing three endemic species, are known. Menzies's own account of the visit is also extant and is transcribed here from his manuscript journal.
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PMID: 21560440
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Abstract
Methanolic extract of Euphorbia cornigera shoots was separated using HPLC, affording compounds 1-4. Their structures and relative stereochemistry were established after obtaining their spectroscopic (IR, (1)H, (13)C NMR COSY-45°, HOHAHA, HSQC, HMBC, NOESY, and mass measurement) data. On the basis o...
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PMID: 21061221
PDF is available here.
Abstract
In order to find antiosteoporotic agents from natural resources, 32 Indonesian medicinal plants were screened for their effects on osteoblast differentiation by using alkaline phosphatase (ALP) activity in MC3T3-E1 osteoblast cells as a marker. From the extract of Barleria lupulina, which showed the...
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PMID: 21213964
PDF is available here.
Abstract
Two new compounds 1 and 2 have been isolated from the aerial parts of Urena lobata L. The structures of the two new compounds were established as ceplignan-4-O-β-d-glucoside (1) and 2,5-dihydroxy benzoic acid-7-(2,6-dimethyl-6-hydroxy-2,7-octadienoic acid) anhydride-5-O-β-d-apiofuranosyl(1 → 2...
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PMID: 21061218
PDF is available here.
Abstract
Pharmacologically motivated natural product investigations have yielded a large variety of structurally unique lead compounds with interesting biomedical properties, but the natural roles of these molecules often remain unknown. In the present investigation, a series of benzyl substituted-flavone de...
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PMID: 21061220
PDF is available here.
Abstract
Biebersteinia multifida is a common herb known in Iran. Its roots have been used locally in folk medicine of western region of Iran in the treatment of many diseases. The antioxidant activity and its inhibition of erythrocyte hemolysis were investigated.
1,1-diphenyl-2-picryl hydrazyl radical (DPPH)...
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PMID: 21222368
PDF is available here.
Abstract
Mycoplasma spp. are obligate parasites of humans and animals. But due to the special requirements needed to culture Mycoplasma in the laboratory, little or no research has been done to evaluate the efficacy of medicinal plants on the organism.
To screen medicinal plants traditionally used to treat i...
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PMID: 20819025
PDF is available here.
Abstract
We found that IAX could suppress various steps of tumor metastasis including proliferation, migration and invasion in a dose-dependent manner on colorectal cancer cells. Especially matrix metalloproteinase 2 (MMP-2), the pivotal factor in cancer invasion, was suppressed both on activation and expres...
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PMID: 20017136
PDF is available here.
Abstract
Eight known and two new triterpenoid derivatives, neemfruitins A (9) and B (10), have been isolated from the fruits of neem, Azadirachta indica, a traditional antimalarial plant used by Asian and African populations. In vitro antiplasmodial tests evidenced a significant activity of the known gedunin...
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PMID: 20669933
PDF is available here.
Abstract
Screening of a total of 86 crude drugs for retinoid X receptor (RXR) ligands demonstrated that the methanol extract of the bark of Magnolia obovata markedly activated the transcriptional activity of RXRalpha in luciferase reporter assays. Thereafter, honokiol (1) was isolated as a constituent able t...
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PMID: 20695472
PDF is available here.
Abstract
Prolyl oligopeptidase (POP) is a serine protease highly expressed in the brain that hydrolyses peptide bonds at the carboxyl terminal of prolyl residues. There is evidence that this enzyme participates in several functions of the central nervous system. Scutellaria racemosa Pers demonstrated signifi...
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PMID: 20117183
PDF is available here.
Abstract
Phytochemical investigation of the stem bark of Trewia nudiflora led to the isolation of two new cardenolides, trewianin (1) and trewioside (2), along with scopoletin (3) and indole-3-carboxylic acid (4). Structures were established by 1D- and 2D NMR spectroscopy, HR-MS analysis, and by comparison w...
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PMID: 20097274
PDF is available here.
Abstract
We report the complete spectroscopic assignments for 3.
Copyright (c) 2010 Elsevier B.V. All rights reserved....
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PMID: 20080158
PDF is available here.
Abstract
Two new iridoid glucosides, named diffusosides A and B, were isolated from the aerial part of Hedyotis diffusa Willd. Their structures were elucidated by 1D-, 2D-NMR spectroscopic analysis and HRESIMS. These two compounds showed no cytotoxic activity against SMMC-7721, SW480, SW620, Bel7402, and Hep...
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PMID: 20080156
PDF is available here.
Abstract
The seed of Cassia obtusifolia Linn have yielded three new compounds, 2-benzyl-4,6-dihydroxy benzoic acid (1), 2-benzyl-4,6-dihydroxy benzoic acid-6-O-beta-D-glucopyranoside (2) and 2-benzyl-4,6-dihydroxy benzoic acid-4-O-beta-D-glucopyranoside (3). Their structures were determined by spectroscopic...
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PMID: 20211226
PDF is available here.
Abstract
Two secolignan glycoside isomers, urticaside A (1) and urticaside B (2), were isolated from the roots of Urtica triangularis Hand.-Mazz. Their structures were elucidated by means of spectral analyses including 1D, 2D NMR and HR-EI-MS.
Copyright (c) 2010 Elsevier B.V. All rights reserved.
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PMID: 20211227
PDF is available here.
Abstract
Phytochemical investigation of the ethanol extract of the leaves of Andrographis paniculata yielded one novel diterpene (13R, 14R) 3, 13, 14, 19-tetrahydroxy-ent-labda-8 (17), 11-dien-16, 15-olide 1 which has an uncommon cis-diol groups in the lactone moiety, and 3, 19-isopropylidene-14-deoxy-ent-la...
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PMID: 20230876
PDF is available here.
Abstract
Phytochemical study on the ethanol extract of the rhizomes of Curculigo breviscapa led to the isolation of two new norlignans, breviscapin C (1) and breviscaside B (2), together with six known norlignans, curcapital (3), capituloside (4), pilosidine (5), curcapitoside (6), crassifoside H (7), and cr...
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PMID: 20079812
PDF is available here.
Abstract
Although the quinolizidine alkaloids and flavonoids, the main active components of the traditional Chinese medicine Sophora flavescens, have been largely investigated, a new matrine alkaloid derivative 9alpha-hydroxy-7,11-dehydromatrine (1) and a rare 1,4-diazaindan-type alkaloid flavascensine (17),...
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PMID: 20079811
PDF is available here.
Abstract
Two new triterpene saponins, paraquinosides A (1) and B (2) were isolated from the aerial parts of Paraquilegia microphylla (Royle) Dromm. et Hutch, a Tibetan ethnic medicine distributed in the Qinghai-Tibet Plateau. On the basis of 1D and 2D NMR evidence, their structure was elucidated as 3-O-alpha...
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PMID: 20176088
PDF is available here.
Abstract
Two new chalcone derivatives named morachalcones B and C (1 and 2) were isolated from the leaves of Morus alba L. Their structures were elucidated by spectroscopic analysis. Morachalcones B (1) and C (2) represent two examples of chalcones having unusual furan rings which are formed by cyclization b...
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PMID: 20211228
PDF is available here.
Abstract
Two new bufadienolides, named tigencaoside A(1) and tigencaoside B(2), were isolated from the rhizomes of Helleborus thibetanus Franch., along with two known bufadienolides, hellebrigenin (3) and 5beta,14beta-dihydroxy-19-oxo-3beta-[(alpha-L-rhamnopyranosyl)oxy]bufa-20,22-dienolide (4). Their struct...
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PMID: 20230875
PDF is available here.
Abstract
Together with apigenine dimethylether and piperchabamide A, a new amide alkaloid, Kaousine and the Z form of antiepilepsirine were isolated from the aerial part of Piper capense L.f (Piperaceae). Their structures were elucidated by spectrometric methods and their in vitro antiparasitic activities we...
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PMID: 20227469
PDF is available here.
Abstract
We focused on wood of Artocarpus heterophyllus which shows anti-melanogenesis activity. By activity-guided fractionation of A. heterophyllus wood extract, a new prenylated flavonoid, 3-prenyl luteolin (1) was isolated. The IC(50) of mushroom tyrosinase inhibitory activity of 1 was 76.3 microM. The r...
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PMID: 20230878
PDF is available here.
Abstract
Rapid micropropagation of Nepeta rtanjensis, N. sibirica and N. nervosa was performed. Qualitative and quantitative nepetalactone content in methanol extracts of in vitro grown plants was analysed by reverse-phase HPLC coupled with UV and MS detection. Only trans,cis-nepetalactone was detected in sh...
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PMID: 20307630
PDF is available here.
Abstract
Tribulus terrestris L. (Zygophyllaceae) is one of the highly traded raw drugs and also used as a stimulative food additive in Europe and USA. While, Ayurvedic Pharmacopoeia of India recognizes T. terrestris as Goksura, Tribulus lanuginosus and T. subramanyamii are also traded by the same name raisin...
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PMID: 20083169
PDF is available here.
Abstract
To investigate the AAPH scavenging activities of 22 flavonoids and phenolic acids and 9 extracts of Chinese materia medica.
The antioxidant activities of the samples were evaluated by an oxygen radical absorbance capacity method (ORAC), at the same time, the total contents of flavonoids and phenolic...
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PMID: 21137342
PDF is available here.
Abstract
The paper discusses the theory regarding to the Chinese material medical (CMM) regionalization. It is based on the studying of papers and practical experience in the field of CMM regionalization. The basic theories of CMM regionalization are laws of territorial differentiation and location theory. T...
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PMID: 21137354
PDF is available here.
Abstract
Alzheimer's disease (AD) is characterized by dysfunctional intracellular and extracellular biochemical processes that result in neuron death. This article summarizes hypotheses regarding cell dysfunction in AD and discusses the effectiveness of, and problems with, different therapies. Pharmaceutical...
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PMID: 21155625
PDF is available here.
Abstract
These results were consistent with validation experiments.
Studying compatibility principle of TCMF by network theory is a new and feasible method....
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PMID: 21141503
PDF is available here.
Abstract
Flavonoids are an important effective component of traditional Chinese medicine, which are widely distributed in the plant kingdom. The biosynthesis of flavonoid in plants is affected and regulated by various environmental factors. For a necessary environmental factor to plant growth and development...
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PMID: 21141479
PDF is available here.
Abstract
Three hydrolyzable tannins, geraniin, corilagin and gallic acid, main active components of Geranium wilfordii Maxim, have been separated and purified in one-step by both reversed-phase and normal-phase high-speed counter-current chromatography. Gallic acid, corilagin and geraniin were purified from...
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PMID: 20549664
PDF is available here.
Abstract
Aristolochic acids (AAs) are a family of structurally related nitrophenanthrene carboxylic acids existing in Aristolochia, Bragantia, and Asarum species. AAs have been proven to have nephrotoxic and carcinogenic toxicity. In this study, a novel pre-column fluorescence derivatization procedure follow...
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PMID: 20399058
PDF is available here.
Abstract
The antibacterial activity of Vernonia cinerea (L.) extract was investigated using the broth dilution method. The extract showed a favorable antimicrobial activity against Pseudomonas aeruginosa with a minimum inhibition concentration (MIC) value of 3.13 mg/mL. V. cinerea extract at (1/2), 1, or 2 t...
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PMID: 20594042
PDF is available here.
Abstract
Lemon balm (Melissa officinalis, Lamiaceae) is a well-known medicinal plant. Amongst the biologically active ingredients are a number of phenolic compounds, the most prominent of which is rosmarinic acid. To obtain better knowledge of the biosynthesis of these phenolic compounds, two enzymes of the...
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PMID: 20563822
PDF is available here.
Abstract
Progress in the studies on responses of medicinal plants to drought stress including changes of appearance, physiological adaptation, biochemistry response and molecular mechanisms were summarized. Committed steps of controlled experiment of medicinal plants to drought stress were proposed consideri...
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PMID: 20931837
PDF is available here.
Abstract
The eleven Chinese herbal medicine containing flavonoids are applied as raw materials to explore the relationship between the inhibitory ratio of nitrosamine synthesis, the scavenging ratio of nitrite and the flavonoid content in the samples. The inhibitory ratio of nitrosamine synthesis and the sca...
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PMID: 20931851
PDF is available here.
Abstract
Four new steroidal saponins (1-4) were isolated from the stem and bark of two species of Dracaena: deistelianosides A and B (1 and 2) from D. deisteliana and arboreasaponins A and B (3 and 4) from D. arborea. Six known saponins and one known sapogenin were also isolated. The structures of 1-4 were e...
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PMID: 20553003
PDF is available here.
Abstract
Four new chromane derivatives, anthopogochromane (1), anthopogochromene A (2), anthopogochromene B (3), and anthopogochromene C (4), and two known compounds, daurichromenic acid (5) and ilicicolinic acid B (6), have been isolated from the Chinese medicinal plant Rhododendron anthopogonoides. The S a...
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PMID: 20586436
PDF is available here.
Abstract
We show that Psychotria leptothyrsa var. longicarpa (Rubiaceae) contains a suite of different cyclotides. The cyclotide fractions were isolated by RP-HPLC, and sequences of six new peptides, named psyles A-F, were determined by MS/MS sequencing. One of these, psyle C, is the first rubiaceous linear...
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PMID: 20575512
PDF is available here.