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Welcome to the Pubget Medical Subject Headings (MESH) browser. Click on a topic or subtopic below to explore related papers. In the gold box is the most recent paper about the current MESH term, and below are 20 related papers.
Steroids (19):
Recent article
Steroids
Abstract
We hypothesized a role for β-AET in obesity. We now report that plasma levels of β-AET positively correlate with BMI in healthy men and women. Together with previous studies, the observations reported here may suggest a compensatory role for β-AET in preventing the development of metabolic syndro...
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PMID: 20847733
PDF is available here.
PDF is available here.
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Abstract
Abstract
To evaluate and compare the efficacy and safety of bronchodilators and steroids, alone or combined, for the acute management of bronchiolitis in children aged less than 2 years.
Systematic review and meta-analysis.
Medline, Embase, Central, Scopus, Pub...
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PMID: 21471175
PDF is available here.
PDF is available here.
Abstract
We analyzed the steroid sensitivity of ovalbumin (OVA) reactive helper T (Th) cell clones both in vitro and in vivo.
For in vitro experiments, Th clones were cultured with antigen-presenting cells, OVA, and various concentrations of dexamethasone (DEX). The proliferative response of...
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PMID: 21646805
PDF is available here.
PDF is available here.
Abstract
A series of novel methyl spongoate (1) analogs has been synthesized and evaluated for their in vitro cytotoxic properties. It was found that the nature of the C-20 side chain had significant effects on their bioactivities and some analogs showed higher cytotoxicity than 1 against A549, HCT-116, HepG...
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PMID: 20728460
PDF is available here.
PDF is available here.
Abstract
A novel and practical procedure was developed for the preparation of D-ring unsaturated 17-alkynyl steroids by Pd(PPh(3))(4)/AgOAc-catalyzed coupling of steroidal 17-triflates and alkynes. Firstly treatment of the steroid-17-ones with PhN(Tf)(2) and KHMDS in dried THF at -78 degrees C for 2h gives t...
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PMID: 20685217
PDF is available here.
PDF is available here.
Abstract
Timosaponin BII (1), a steroidal saponin showing potential anti-dementia activity, was regioselectively hydrolyzed into its deglycosyl derivatives by the crude enzyme from Aspergillus niger AS 3.0739. Three biotransformation products, timosaponin BII-a (2), timosaponin BII-b (3), and timosaponin BII...
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PMID: 21061217
PDF is available here.
PDF is available here.
Abstract
We retrospectively analyzed 27 patients treated during 5 years with ECP for steroid-refractory acute and chronic GVHD. We performed an "off-line" approach using a continuous flow cell separator (Cobe Spectra) and a Ultraviolet A irradiator (UVAMATIC). Among acute GVHD patients, 11 of 21 obtained a c...
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PMID: 20962677
PDF is available here.
PDF is available here.
Abstract
Abstract
We conducted a retrospective cohort study to determine exposures associated with illness. Eligible patients had an invasive procedure in the 4 days before or after the procedure date of the initial case-patients. Infection control assessments were made, and environmental specimens collected.
Four la...
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PMID: 20975462
PDF is available here.
PDF is available here.
Abstract
Abstract
We report 4 cases to support this postulation. The patients were male adults aged 42 to 89 years, who presented with an infiltrative, firm cervical mass. Two patients also had IgG4-related chronic sclerosing sialadenitis of submandibular gland and lymphadenopathy. Histologically, the cervical soft t...
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PMID: 20871392
PDF is available here.
PDF is available here.
Abstract
We report the screening for the mRNA expression of the ACTH-R, steroidogenic acute regulatory protein (StAR), cholesterol side-chain cleavage enzyme, 3β-hydroxysteroid dehydrogenase, 21-hydroxylase (all in 38 cortisol-secreting ATs), 17α-hydroxylase, and 11β-hydroxylase (both in 28 cortisol-secre...
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PMID: 20920783
PDF is available here.
PDF is available here.
Arerugi = [Allergy] (59)11 2010
Abstract
Arerugi = [Allergy] (59)11 2010
Abstract
Abstract
Asporyergosterol (1), a new steroid with an E double bond between C-17 and C-20, was identified from the culture extracts of Aspergillus oryzae, an endophytic fungus isolated from the marine red alga Heterosiphonia japonica. Moreover, four known steroids including (22E,24R)-ergosta-4,6,8(14),22-tetr...
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PMID: 21121251
PDF is available here.
PDF is available here.
Dermatologic Clinics (28)4 2010
Abstract
Vulvodynia is a multifactorial chronic pain disorder that is distressing to the patient and exigent to the physician. Although the condition is common, it remains little understood, so patients remain undiagnosed and untreated or undertreated for many years. Although multiple therapies exist in the...
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PMID: 20883912
PDF is available here.
PDF is available here.
European Journal of Cancer (46)15 2010
Abstract
Spinal metastases are the most frequently encountered spinal tumour and can affect up to 50% of cancer patients. Both the incidence and prevalence of metastases are thought to be rising due to better detection and treatment options of the systemic malignancy resulting in increased patient survival....
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PMID: 20627705
PDF is available here.
PDF is available here.
Anticancer Research (30)10 2010
Abstract
Modified steroidal derivatives (PK11-PK14) of p-bis(2-chloroethyl)aminophenyl propenate (PK15) were used to study their antitumour activity on Lewis lung carcinoma (LLC) and their effect on sister chromatid exchanges (SCEs) and human lymphocyte proliferation kinetics.
LLC was tested in this study. C...
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PMID: 21036741
PDF is available here.
PDF is available here.
Abstract
We present a retrospective review of 4 patients with previously undiagnosed sarcoidosis who presented with atypical signs and symptoms of sarcoidosis: dysphonia with isolated vocal fold involvement; cough and globus pharyngeus; pediatric sarcoidosis; and severe bilateral vocal fold paresis and dysph...
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PMID: 21049851
PDF is available here.
PDF is available here.
Journal of Chromatography A (1217)44 2010
Abstract
The use of liposomes as coating materials in capillary electrophoresis has recently emerged as an important and popular research area. There are three preparation methods that are commonly used for coating capillaries with liposomes, namely physical adsorption, avidin-biotin binding and covalent cou...
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PMID: 20870242
PDF is available here.
PDF is available here.
Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia (21)5 2010
Abstract
Our study revealed that there was a high prevalence of iSRNS and preponderance of non-MCD lesions, with MPGN and FSGS being the major morphologic lesions. The outcome with steroid and cyclophosphamide-based treatment for iSRNS was further enhanced with addition of either lisinopril or spironolactone...
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PMID: 20814150
PDF is available here.
PDF is available here.
Journal of Arthroplasty (25)6 Suppl 2010
Abstract
We thereby believe that this is a reliable test with low morbidity and can predict the potential benefit of total hip arthroplasty in this diagnostically challenging group of patients.
Copyright 2010 Elsevier Inc. All rights reserved....
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PMID: 20570105
PDF is available here.
PDF is available here.
Abstract
A 56-year-old woman presented with pronounced petechia. She complained about recurrent fever and night sweat for two weeks, having felt unwell during the past years. INVESTIGATIONS: Laboratory examinations showed thrombocytopenia, leukopenia and considerably elevated liver enzymes. Antinuclear antib...
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PMID: 20812155
PDF is available here.
PDF is available here.
Abstract
We describe the case of a 14-year-old boy with steroid-induced osteoporosis, who was treated by pamidronate. This patient exhibited linearly increased bilateral uptake in the shafts of his femora, tibiae, radii, and ulnae that were parallel to the growth plates. A simple radiograph corresponding bon...
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PMID: 20706059
PDF is available here.
PDF is available here.
Abstract
Military Medicine (175)8 2010
Abstract
We present a case in which a 25-year-old, Hispanic woman presented with seizures, memory loss, and unusual behavioral changes. The woman had a teratoma removed 2 months earlier. Because of the time course, a paraneoplastic syndrome was initially considered unlikely. Brain imaging, electroencephalogr...
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PMID: 20731268
PDF is available here.
PDF is available here.
Phytomedicine (17)10 2010
Abstract
A series of Sarsapogenin and Diosgenin derived steroidal constituents (1-12), isolated from Solanum xanthocarpum and Asparagus racemosus were screened for their ability to induce cell death and apoptosis of colon carcinoma cells. The carbohydrate moieties linked to the steroid backbones were found t...
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PMID: 20176464
PDF is available here.
PDF is available here.
Abstract
The purpose of this study was to develop smart polymer based controlled delivery systems to deliver steroidal hormones after single subcutaneous (s.c.) injection at predetermined rates over extended period of time. In vivo absorption and pharmacokinetics of levonorgestrel (LNG) and t...
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PMID: 20213838
PDF is available here.
PDF is available here.
Abstract
Four new steroidal saponins (1-4) were isolated from the stem and bark of two species of Dracaena: deistelianosides A and B (1 and 2) from D. deisteliana and arboreasaponins A and B (3 and 4) from D. arborea. Six known saponins and one known sapogenin were also isolated. The structures of 1-4 were e...
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PMID: 20553003
PDF is available here.
PDF is available here.
Journal of Biological Chemistry (285)29 2010
Abstract
We demonstrate that ARR19 inhibits the transactivation of orphan nuclear receptor Nur77, which is one of the major transcription factors that regulate the expression of steroidogenic enzyme genes in Leydig cells. ARR19 physically interacts with Nur77 and suppresses Nur77-induced promoter activity of...
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PMID: 20472563
PDF is available here.
PDF is available here.
Abstract
We tested this hypothesis by presenting humans' closest living relatives, chimpanzees (Pan troglodytes) and bonobos (Pan paniscus), with a dyadic food competition and measuring their salivary testosterone and cortisol levels. Given that chimpanzees and bonobos differ markedly in their food-sharing b...
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PMID: 20616027
PDF is available here.
PDF is available here.
Abstract
It has been reported that 10-50% of patients with pruritus but no skin rash have an underlying systemic disease and up to 70% a psychiatric one. The aim of this retrospective study was to review the records of a large number of patients with chronic pruritus for concomitant diseases and treatment op...
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PMID: 20574605
PDF is available here.
PDF is available here.
Abstract
I minute Apgar scores, our results do not support utilization of these cord blood levels as the sole tool to predict neonatal outcome....
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PMID: 20862823
PDF is available here.
PDF is available here.
Abstract
A 36-year-old woman was given a diagnosis of hemophagocytic syndrome associated with systemic lupus erythematosus, and was treated with high-dose methylprednisolone and etoposide. She needed endotracheal intubation for mechanical ventilation because of respiratory failure. She developed hoarseness a...
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PMID: 20684210
PDF is available here.
PDF is available here.
Abstract
Three new compounds were isolated from the dried bulbs of Allium macrostemon Bunge. Their structures were elucidated from their spectral data as (25R)-26-O-beta-D-glucopyranosyl-5alpha-furostane-3beta,12beta,22,26-tetraol-3-O-beta-D-glucopyranos-yl (1-->2) [beta-D-glucopyranosyl (1-->3)]-beta-D-gluc...
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PMID: 20657379
PDF is available here.
PDF is available here.
Abstract
We have investigated the antibacterial activity of some new steroidal thiosemicarbazones and their Pd(II) metal complexes were prepared by the reaction of the thiosemicarbazones with [Pd(DMSO)(2)Cl(2)]. The steroidal thiosemicarbazones were prepared by the reaction of thiosemicarbazides with a stero...
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PMID: 20657393
PDF is available here.
PDF is available here.
Abstract
We aim to review and critically evaluate literature focusing on the incidence and clinical presentations of major complications associated with cervical transforaminal steroid injections. The goal of this review is to identify pertinent journal information that aids in the improvement in clinical ca...
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PMID: 20567139
PDF is available here.
PDF is available here.
Abstract
Autoimmune pancreatitis (AIP) has been extensively reported from Japan, Europe, and the United States. Whereas the descriptions of AIP from Japan have predominantly been based on the presence of a distinct clinical phenotype, reports from Europe and the United States describe at least 2 histopatholo...
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PMID: 20562576
PDF is available here.
PDF is available here.
Abstract
Abstract
Abstract
We have reported two cases of the patients with acute steroid-refractory GVHD who underwent allogeneic HSCT. These patients received infusions of third-party clonal mesenchymal stem cells (cMSCs), which were isolated by a subfractionation culturing method (SCM) developed recently by our group, and s...
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PMID: 20514533
PDF is available here.
PDF is available here.
Abstract
Abstract
Mutations in the PLCE1 gene encoding phospholipase C epsilon 1 (PLCepsilon1) have been recently described in patients with early onset nephrotic syndrome (NS) and diffuse mesangial sclerosis (DMS). In addition, two cases of PLCE1 mutations associated with focal segmental glomeruloscl...
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PMID: 20591883
PDF is available here.
PDF is available here.
Abstract
Beneficial impact of ANS on mortality and composite BPD/mortality is evident only after a complete course and persists even with its administration beyond a week from delivery....
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PMID: 20297898
PDF is available here.
PDF is available here.
Endocrinology (151)7 2010
Abstract
We address the molecular and cellular mechanisms underlying the effects of MEHP on basal and human chorionic gonadotropin (hCG)-stimulated steroid production by MA-10 Leydig cells, using a systems biology approach. MEHP induced dose-dependent decreases in hCG-stimulated steroid formation. Changes in...
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PMID: 20463053
PDF is available here.
PDF is available here.
Abstract
GFR showed no significant difference at month 12, with 56.1 in group A versus 58.4 mL/min/1.73 m in group B. In functioning grafts, renal function was significantly better in the SRL group, with higher GFR values at months 1, 2, 3, 6, and 9 (P<0.05). At month 12, patient survival and incidence of bi...
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PMID: 20386144
PDF is available here.
PDF is available here.
Abstract
Delay of Tac does not benefit renal function in liver transplant recipients with a good renal function at baseline....
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PMID: 20495510
PDF is available here.
PDF is available here.
Abstract
Abstract
Anaphylaxis is the quintessential medical emergency where prompt recognition and treatment is life-saving. In the UK the incidence is increasing year on year, and is most common in the sixth and seventh decades of life. More than half of cases are iatrogenic in nature, most of the rest are caused by...
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PMID: 21125060
PDF is available here.
PDF is available here.
Abstract
We found that trophozoite and schizont stages were the most sensitive to SNs. By Giemsa-stained smears, induction of crisis forms was observed. Transmission electron microscopy of treated parasites showed morphological abnormalities such as a cytoplasm rich in vesicles and myelinic figures. The Mito...
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PMID: 20153445
PDF is available here.
PDF is available here.
Abstract
The 17-oxo-17a-aza-d-homo-5-androsten-3beta-yl esters (13-22) were synthesized from commercially available (25R)-5-spirosten-3beta-ol (Diosgenin) (6) as starting material. The synthesized compounds were evaluated for their antiproliferative activity, acute toxicity and effect on serum androgen level...
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PMID: 20171759
PDF is available here.
PDF is available here.
Abstract
Response to treatment with systemic steroids, AZA/6-MP and infliximab are not related to NOD2/CARD15 mutations, age of diagnosis and disease behavior. Patients with colonic disease have higher rates of steroid dependency....
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PMID: 19693669
PDF is available here.
PDF is available here.
Journal of Critical Care (25)2 2010
Abstract
Treatment and evaluation of critical illness-related corticosteroid insufficiency in critically ill patients at our institution are inconsistent. Many patients with VDSS do not receive either treatment or evaluation for critical illness-related corticosteroid insufficiency, and patients who do not m...
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PMID: 19781894
PDF is available here.
PDF is available here.
Chemosphere (80)1 2010
Abstract
Our study demonstrates the applicability of the test with P. antipodarum for a variety of sediments and once again points out the need of suitable in vivo biotests for the risk assessment of field sediments.
2010 Elsevier Ltd. All rights reserved....
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PMID: 20417543
PDF is available here.
PDF is available here.
Abstract
A series of new polyoxygenated steroid derivatives with various steroid skeleton moieties were synthesized. Antitumor activity of the compounds against three tumor cell lines (Breast cancer MCF7, lung cancer NCI and oral cancer KB) were evaluated. Compounds with aromatic A ring of this series exhibi...
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PMID: 20188119
PDF is available here.
PDF is available here.
Abstract
A facile strategy for the annulation of 2,6-dicyanoaniline moiety to steroidal A/B-ring is described from base catalyzed and microwave-promoted reaction of steroidal 3-keto-2-hydroxymethylenes with malononitrile in high yields. The generality of the reaction has been extended to non-steroidal cyclic...
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PMID: 20178810
PDF is available here.
PDF is available here.
Abstract
The reaction of 3beta-hydroxy-21-hydroxymethylidenepregn-5-en-3beta-ol-20-one (1) with phenylhydrazine (2a) affords two regioisomers, 17beta-(1-phenyl-3-pyrazolyl)androst-3-en-3beta-ol (5a) and 17beta-(1-phenyl-5-pyrazolyl)androst-5-en-3beta-ol (6a). The direction of the ring-closure reactions of 1...
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PMID: 20206195
PDF is available here.
PDF is available here.
Abstract
We provide a brief overview of the mechanisms by which sphingolipids regulate steroidogenesis. In addition, we discuss how steroid hormones control sphingolipid metabolism. Finally, we outline evidence supporting the emerging role of bioactive sphingolipids in various nuclear processes and discuss a...
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PMID: 20138078
PDF is available here.
PDF is available here.