Find your PDFs fast.
Welcome to the Pubget Medical Subject Headings (MESH) browser. Click on a topic or subtopic below to explore related papers. In the gold box is the most recent paper about the current MESH term, and below are 20 related papers.
Respiratory System (7):
Recent article
Respiratory System
Abstract
| < More recent | Older article > |
Respirology (16 Suppl 2) 2011
Abstract
Nature Immunology (12)5 2011
Abstract
We will discuss how the expression of IL-22 and IL-22R is regulated, the functions of the IL-22-IL-22R pathway in regulating immunity, inflammation and tissue homeostasis, and the therapeutic potential of targeting this pathway in human disease....
|
PMID: 21502992
PDF is available here.
PDF is available here.
Mucosal Immunology (4)2 2011
Abstract
We find that exposure of bronchiolar epithelial cells to pyocyanin results in MUC2/MUC5AC induction and mucin secretion through release of inflammatory cytokines and growth factors (interleukin (IL)-1β, IL-6, heparin-bound epidermal growth factor, tissue growth factor-α, tumor necrosis factor-α)...
|
PMID: 20962773
PDF is available here.
PDF is available here.
Abstract
We therefore examined the effect of astilbic acid in a mouse model in which asthma was established by sensitization and challenge with ovalbumin (OVA). Astilbic acid inhibited OVA-induced AHR to inhaled methacholine and significantly suppressed the levels of T-helper 2-type cytokines (including IL [...
|
PMID: 21168540
PDF is available here.
PDF is available here.
Epidemiology and Infection (138)12 2010
Abstract
We collected respiratory tract samples of adult outpatients with symptoms of pneumonia in a German nationwide network and detected M. pneumoniae by real-time PCR in 140 specimens. The strains were typed by sequencing and demonstrated the circulation of subtypes 1 and 2 and variants 2a and 2b. The ov...
|
PMID: 20334729
PDF is available here.
PDF is available here.
Anesthesiology (113)6 2010
Abstract
We hypothesized that neostigmine administered after recovery of the train-of-four (TOF) ratio impairs upper airway integrity and genioglossus muscle function.
We measured, in 10 healthy male volunteers, epiglottic and nasal mask pressures, genioglossus electromyogram, air flow, respiratory timing, a...
|
PMID: 20980910
PDF is available here.
PDF is available here.
Toxicology (276)2 2010
Abstract
Young adult male Wistar rats, a species commonly used in inhalation toxicity studies, and OF1 mice, a species often used in sensory irritation studies, were simultaneously nose-only exposed for 45-min to ammonia in concentrations from 92 to 1243 mg/m(3). This study examined airway reflexes by the ch...
|
PMID: 20692317
PDF is available here.
PDF is available here.
Vnitrni lekarstvi (56)10 2010
Abstract
Obesity is an independent risk factor for the development and progression of hypertension, cardiovascular disease and chronic kidney disease. There is growing evidence that obesity and associated metabolic abnormalities may induce and accelerate renal complications in essential hypertension. The clu...
|
PMID: 21105455
PDF is available here.
PDF is available here.
Abstract
Mucociliary clearance (MC), designed by evolution to eliminate inhaled and possibly noxious material from the airways, considerably limits the benefit of inhalation therapy. Although the principles of MC seem to be understood, there are still many open questions on mucociliary particle clearance. In...
|
PMID: 20500091
PDF is available here.
PDF is available here.
Abstract
Airway mucus hypersecretion is a pathophysiological feature of asthma and chronic obstructive pulmonary disease (COPD). The hypersecretion is associated with phenotypic changes in the airways, notably, increases in the number of surface epithelial goblet cells (hyperplasia) and in the size of the su...
|
PMID: 20695774
PDF is available here.
PDF is available here.
Abstract
Recently, many victims of improvised explosive devices have shown varying degrees of facial injuries in different patterns with or without flash burns. In addition, patients have had intense thermal inhalation that leads to oral-nasal-pharyngeal edema and toxic fume inhalation that may require the m...
|
PMID: 20537780
PDF is available here.
PDF is available here.
Abstract
The prevalence rate of GAS carriage is high in school-age children from Tulufan and Buerjin of Xinjiang Province. The GAS carrier rate is associated with the season and ethic group. The children from Buerjin County present a higher GAS carrier rate than those from Tulufan City....
|
PMID: 20704792
PDF is available here.
PDF is available here.
Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology (26)8 2010
Abstract
To investigate the effect of ERK signaling pathway on apoptosis of airway smooth muscle cells (ASMCs) in chronic asthmatic rats.
Thirty Wistar rats were assigned to two groups: control group (A group, n = 15)and chronic asthmatic group (B group, n = 15). The apoptosis of ASMCs were detected by Situ...
|
PMID: 20619097
PDF is available here.
PDF is available here.
Journal of Virology (84)16 2010
Abstract
We generated recombinant human A/Vietnam/1203/04 (VN; clade 1) and A/Turkey/15/06 (TK; clade 2.2) influenza viruses containing the H274Y neuraminidase (NA) mutation, which confers resistance to NA inhibitors, and compared the fitness levels of the wild-type (WT) and resistant virus pairs in ferrets....
|
PMID: 20519385
PDF is available here.
PDF is available here.
Abstract
Lung, cardiovascular system, liver and kidney are some examples for organs that develop ramified three-dimensional networks of epithelial tubes. The tube morphology affects flow rates of transported materials, such as liquids and gases. Therefore, it is important to understand how tu...
|
PMID: 20403463
PDF is available here.
PDF is available here.
Abstract
The following are the proceedings of a symposium held at the Second International Congress for Respiratory Science in Bad Honnef, Germany. The goals of the symposium were to delineate the blood-gas barrier phenotype across vertebrate species; to delineate the interrelationship betwee...
|
PMID: 20096383
PDF is available here.
PDF is available here.
Abstract
Molecular Microbiology (77)1 2010
Abstract
We showed the gene in all tested pneumococci and identified that the observed differences in the molecular mass of PavB rely on the number of repeats, ranging from five to nine SSURE. PavB interacted with fibronectin and plasminogen in a dose-dependent manner as shown by using various SSURE peptides...
|
PMID: 20444103
PDF is available here.
PDF is available here.
Influence of airway wall stiffness and parenchymal tethering on the dynamics of bronchoconstriction.
Abstract
We used lung explants to investigate the effects of enzymatic digestion on the rate and magnitude of airway narrowing induced by acetylcholine. To link the observed changes in narrowing dynamics to the degree of alteration in tissue mechanics, we compared our experimental results with predictions ma...
|
PMID: 20435686
PDF is available here.
PDF is available here.
Abstract
We demonstrate that human ASM mitogens including PDGF, EGF, and thrombin stimulate protein synthesis. Surprisingly, pleiotropic cytokines IFN-beta and IFN-gamma, which inhibit ASM proliferation, also increased cytosolic protein content in ASM cells. Thus IFN-beta alone significantly increased protei...
|
PMID: 20382746
PDF is available here.
PDF is available here.
Abstract
We assessed the impact of mPGES-1 deletion in a mouse model of ozone-induced airway hyper-responsiveness. Ozone exposure increased total lung resistance to inhaled methacholine in wild-type mice. Deletion of mPGES-1 had little effect on total lung resistance in either naive or ozone-exposed animals....
|
PMID: 20371706
PDF is available here.
PDF is available here.
Abstract
Control of the heart rate and cardiorespiratory interactions (CRI) is predominantly parasympathetic in all jawed vertebrates, with the sympathetic nervous system having some influence in tetrapods. Respiratory sinus arrhythmia (RSA) has been described as a solely mammalian phenomenon but respiration...
|
PMID: 20464342
PDF is available here.
PDF is available here.
Nature Immunology (11)7 2010
Abstract
Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery (45)7 2010
Abstract
Abstract
We examined the effects of respiratory muscle work [inspiratory (W(r-insp)); expiratory (W(r-exp))] and arterial oxygenation (Sp(O(2))) on exercise-induced locomotor muscle fatigue in patients with chronic obstructive pulmonary disease (COPD). Eight patients (FEV, 48 +/- 4%) performed constant-load...
|
PMID: 20445160
PDF is available here.
PDF is available here.
Abstract
We tested the hypothesis that exposure to neonatal intermittent hypoxia (n-IH) in rat pups alters central integrative processes following acute and intermittent peripheral chemoreceptor activation in adults. Newborn male rats were exposed to n-IH or normoxia for 10 consecutive days after birth. We t...
|
PMID: 20410478
PDF is available here.
PDF is available here.
Abstract
In 1941, August Krogh published a monograph entitled The Comparative Physiology of Respiratory Mechanisms (Philadelphia, PA: University of Pennsylvania Press, 1941). Since that time comparative studies have continued to contribute significantly to our understanding of the fundamentals of respiratory...
|
PMID: 20357023
PDF is available here.
PDF is available here.
Abstract
The objective of this experiment was to evaluate the central and peripheral expression of selected pro-inflammatory cytokines and Toll-like receptors (TLRs) in pigs infected with porcine reproductive and respiratory syndrome virus (PRRSV). Twenty-four 8-week-old pigs were inoculated with either ster...
|
PMID: 20189253
PDF is available here.
PDF is available here.
Abstract
In 137,819 patient-years of observation (median, 7.3 years/patient), 2537 CF patients died and 5759 patients had MRSA detected. The mortality rate was 18.3 deaths (95% confidence interval [CI], 17.5-19.1) per 1000 patient-years in patients without MRSA and 27.7 deaths (95% CI, 25.3-30.4) per 1000 pa...
|
PMID: 20551409
PDF is available here.
PDF is available here.
Archives of Virology (155)6 2010
Abstract
We further show here that suppression of this sialic acid by siRNA against a sialyltransferase, ST3GAL4, can inhibit H5N1 avian influenza virus infection and that this gene is abundantly expressed in human pharynx, trachea and bronchus. These data suggest that the ST3GAL4 gene is responsible for bio...
|
PMID: 20383541
PDF is available here.
PDF is available here.
Archives of Virology (155)6 2010
Abstract
The mechanisms responsible for virulence of influenza viruses in humans remain poorly understood. A prevailing hypothesis is that the highly pathogenic virus isolates cause a severe cytokinemia precipitating acute respiratory distress syndrome and multiple organ dysfunction syndrome. Cynomolgus maca...
|
PMID: 20372944
PDF is available here.
PDF is available here.
Journal of Critical Care (25)2 2010
Abstract
The risk of abnormal aEEG is high in sick neonates with PPHN or complex CHD. Prospective evaluation of the relationship between aEEG recordings in these disorders and acute cardiorespiratory physiology, comprehensive neuroimaging, and long-term patient outcomes is needed.
Crown Copyright (c) 2010....
|
PMID: 19327328
PDF is available here.
PDF is available here.
Abstract
We examined respiratory secretions by using PCR. XMRV-specific sequences were detected in 2%-3% of samples from 168 immunocompetent carriers and approximately 10% of samples from 161 immunocompromised patients....
|
PMID: 20507757
PDF is available here.
PDF is available here.
Abstract
A subpopulation of nociceptive primary sensory neurons expresses six different transient receptor potential (TRP) ion channels of the vanilloid (V1, V2, V3 and V4), melastatin (M8) and ankyrin (A1) subtypes. TRPV1 mediates the tussive action of capsaicin, which is widely used in cough provocation st...
|
PMID: 20419599
PDF is available here.
PDF is available here.
New Zealand Medical Journal (123)1313 2010
Abstract
Bones from the majority of commonly eaten New Zealand fish species are poorly visible when X-rayed in a background of soft tissue density. Given fishbones frequently impact in regions of high tissue density, plain radiography would appear insufficiently sensitive to exclude upper aerodigestive tract...
|
PMID: 20581893
PDF is available here.
PDF is available here.
Abstract
Although the potential for some residual confounding by smoking could not be eliminated, these data suggest that CRF is inversely associated with lung cancer mortality in men. Continued study of CRF in relation to lung cancer, particularly among smokers, may further our understanding of disease etio...
|
PMID: 19996990
PDF is available here.
PDF is available here.
Abstract
Second hand cigarette smoke consists predominantly of nanoparticles (with two dimensions less than 100 nanometres). The aim of this study was to examine the aerosol of cigarette smoke suspended in the air of a smoking room, its disappearance over the course of time, and its retention in the airways...
|
PMID: 20569876
PDF is available here.
PDF is available here.
Abstract
An extensive toxicology programme on salmeterol hydroxynaphthoate (Serevent), a marketed long-acting beta(2)-adrenoceptor agonist, has been carried out. The studies evaluated both the local (respiratory tract) and systemic tolerance to single and repeated dosing, effects on all stages of reproductio...
|
PMID: 20219844
PDF is available here.
PDF is available here.
Abstract
We assessed epidemiologic data and respiratory samples collected from attendees who sought treatment for influenza-like illness at emergency clinics in Sydney during this outbreak. Isolated influenza viruses were compared with seasonal influenza viruses from the 2008 influenza season. From 100 infec...
|
PMID: 20409371
PDF is available here.
PDF is available here.
Abstract
Abstract
We would predict that higher aPO(2) would be associated with higher critical PO(2) values (CritPO(2)) and lower maximal tracheal conductances (G(max)). We measured CritPO(2) and G(max) for adult and larval vinegar flies reared for 7-9 generations in 10, 21 or 40 kPa O(2). The CritPO(2), CO(2) emissi...
|
PMID: 19682996
PDF is available here.
PDF is available here.
Abstract
Fish and amphibians utilise a suction/force pump to ventilate gills or lungs, with the respiratory muscles innervated by cranial nerves, while reptiles have a thoracic, aspiratory pump innervated by spinal nerves. However, fish can recruit a hypobranchial pump for active jaw occlusion during hypoxia...
|
PMID: 20396858
PDF is available here.
PDF is available here.
Journal of Ethnopharmacology (128)3 2010
Abstract
The four major Stemona alkaloids in Stemona tuberosa do not contribute equally to antitussive potency in guinea pigs. Neotuberostemonine, tuberostemonine and stemoninine target on peripheral cough reflex pathway. Croomine acts on central sites in the cough reflex pathway and demonstrates central res...
|
PMID: 20219659
PDF is available here.
PDF is available here.
Abstract
Sounds from humpback whale songs were analyzed to evaluate possible mechanisms of sound production. Song sounds fell along a continuum with trains of discrete pulses at one end and continuous tonal signals at the other. This graded vocal repertoire is comparable to that seen in false killer whales [...
|
PMID: 20370048
PDF is available here.
PDF is available here.
Abstract
This study did not demonstrate a link between KIPyV infection and symptomatic respiratory disease. Patients positive for KIPyV exhibited less severe clinical symptoms than patients positive for RSV....
|
PMID: 19949359
PDF is available here.
PDF is available here.
Abstract
This study was conducted to determine if microbial infection was a significant factor in patients with undiagnosed craniofacial pain. Of the 150 patients from whom intra-bony cultures were obtained, 23 different groups of isolates were obtained. There were 49 (32.67%) patients whose cultures exhibit...
|
PMID: 20491231
PDF is available here.
PDF is available here.
Abstract
Management of the airway in multitrauma patients is a critical resuscitation task. Prehospital airway management is difficult with a high risk of failure, complications, or both. In-hospital performed conventional oral intubation with manual in-line stabilization, cricoid pressure, and a backup plan...
|
PMID: 20042974
PDF is available here.
PDF is available here.
Abstract
We found clear evidence of effects of PM10 on the occurrence of asthma symptom episodes, and to a lesser extent on cough and PEF. The results for NO2 are more difficult to interpret because they depend on the lag times examined. There was an indication of effect modification by several study conditi...
|
PMID: 20064785
PDF is available here.
PDF is available here.
Abstract
The role of non-motile (primary) cilia as sensory antennae critical for metazoan development and physiology has surfaced over the last decade, long after the function of motile cilia in propelling cells or moving fluids across tissues was well established. A new study of motile cilia...
|
PMID: 19837686
PDF is available here.
PDF is available here.
Abstract
Abstract
In order to optimise the monitoring of potentially exposed workers, it is desirable to determine specific values of absorption for the compounds handled. This study derives specific values of absorption rates for different chemical forms of plutonium from in vitro and animal (monkeys, dogs, mice, ra...
|
PMID: 20220216
PDF is available here.
PDF is available here.
Planta Medica (76)4 2010
Abstract
Our aim was to investigate the impact of thymol by using thyme extracts with either normal or extremely low thymol concentrations (< 0.005 % or > 0.038 %). The antispasmodic effect on smooth muscles of the trachea and the ileum and the effect on ciliary activity (respiratory clearance) were investig...
|
PMID: 19809973
PDF is available here.
PDF is available here.
Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue (22)3 2010
Abstract
Minerva anestesiologica (76)3 2010
Abstract
Inhalation agents represent a basic drug used in modern balanced anesthesia. In the present review, the pharmacokinetics, effectiveness and clinical effects of inhalation agents on different systems are discussed. Data concerning the metabolism and related toxicity of halogenated agents is reviewed,...
|
PMID: 20203550
PDF is available here.
PDF is available here.
Avian Diseases (54)1 Suppl 2010
Abstract
Twelve-week-old Vanaraja (an Indian native dual purpose breed) chickens were inoculated intranasally with different doses (100, 1000, and 10,000 mean embryo infective dose [EID50]) of H5N1 virus, and the clinical disease and pathologic changes were compared. Although the overall severity of clinical...
|
PMID: 20521697
PDF is available here.
PDF is available here.
Abstract
Cluster analysis in patients with severe asthma has suggested the presence of four distinct clinical phenotypes, two with eosinophilic airway inflammation, and two without. Patients with eosinophilic inflammation benefit most from a management strategy targeting the sputum eosinophil count. Molecula...
|
PMID: 19907311
PDF is available here.
PDF is available here.
Abstract
Recently investigated antioxidant therapies for airway inflammation may be broadly grouped into three categories: endogenous metabolic agents, vitamins/nutrients, and botanical extracts. Studies examining effects in upper airway inflammation are limited and primarily consist of in-vitro human and in...
|
PMID: 19935060
PDF is available here.
PDF is available here.
Abstract
Molecular mechanisms of hereditary angioedema reviewed in the literature conclude that it is an autosomal dominant disorder, characterized by the deficiency of C1 inhibitor due to mutations of its gene (SERPING). Hereditary angioedema manifests as episodes of localized swelling in any site of the bo...
|
PMID: 19949324
PDF is available here.
PDF is available here.
Abstract
We summarize recent findings regarding the role of mast cells and basophils in allergic responses and the regulation of signaling pathways downstream of the IgE receptor, the chief inducer of mast cell and basophil activation. We also highlight studies addressing the roles of the protein tyrosine ki...
|
PMID: 19996739
PDF is available here.
PDF is available here.