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Deep Brain Stimulation (0):
Recent article
Deep Brain Stimulation
Abstract
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Psychiatria Danubina (23)1 2011
Abstract
Motor fluctuations and dyskinesia in later stages of Parkinson's disease (PD) are caused by pharmacokinetic as well as pharmacodynamic factors, intermittent dopaminergic stimulation being one of the most important. In the healthy brain, dopamine neurons in the substantia nigra pars c...
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PMID: 21448103
PDF is available here.
PDF is available here.
Versicherungsmedizin / herausgegeben von Verband der Lebensversicherungs-Unternehmen e.V. und Verband der Privaten Krankenversicherung e.V (62)4 2010
Abstract
In Germany about 300,000 to 400,000 people are suffering from Morbus Parkinson at present. It is one of the most common neurological diseases both in Germany and in Europe as a whole. With the rising number of elderly people in our population, the number of Parkinson patients will strongly increase...
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PMID: 21192482
PDF is available here.
PDF is available here.
Clinical Neurophysiology (121)12 2010
Abstract
Experimental Neurology (226)2 2010
Abstract
We tested whether such spontaneous fear-like behaviour could be observed in an open-field test 12 h after dlPAG stimulation. Further, we tested whether this fear-like behaviour could be attenuated by acute or chronic administration of buspirone and escitalopram. Our data demonstrate for the first ti...
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PMID: 20837005
PDF is available here.
PDF is available here.
Revue Neurologique (167)2 2011
Abstract
Movement disorders, especially dystonia, are a frequent manifestation of neurometabolic diseases. Proper characterization and classification of movement disorders is crucial but may be challenging in this setting. The diagnostic work-up should be focused first on treatable disease. Mixed movement dis...
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PMID: 21087782
PDF is available here.
PDF is available here.
Abstract
Abstract
We hypothesized that OCD patients will select a combination of medication and psychotherapy as their most preferred choice overall.
The authors designed a treatment-preference survey using 2 health economics methods, forced-choice and contingent-ranking methods, to elicit preferences for OCD treatme...
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PMID: 21114948
PDF is available here.
PDF is available here.
Abstract
We review DBS in the treatment of gait disturbance due to Parkinson disease and dystonia....
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PMID: 21068459
PDF is available here.
PDF is available here.
Ideggyogyaszati szemle (63)9-10 2010
Abstract
Preoperatively, the patients used 12.05 +/- 4.57 tablets a day out of 3.19 +/- 0.97 different antiparkinsonian drugs, which was significantly reduced by deep brain stimulation to the application of 7.00 +/- 2.96 tablets out of 1-3 (1.84 +/- 0.76) drugs (p < 0.001). Meanwhile, the usage of amantadine...
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PMID: 21033420
PDF is available here.
PDF is available here.
Australasian Psychiatry (18)5 2010
Abstract
The aim of this paper is to discuss the restriction of electroconvulsive therapy (ECT) to the treatment of psychiatric disorders and the prohibition of psychosurgery and deep brain stimulation (DBS) in the NSW Mental Health Act 2007 (MHA), and to examine these restrictions from clinical and human ri...
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PMID: 20863180
PDF is available here.
PDF is available here.
Abstract
We use a modeling approach which is utilized to study the influence of deep brain stimulation on the restoration of segregated activity in the target structures. Besides the spontaneous activity of the target network, the model considers a weak sensory input mimicking signal processing tasks, electr...
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PMID: 20811089
PDF is available here.
PDF is available here.
Neuroscience Letters (481)2 2010
Abstract
We studied the effect of low-frequency stimulation (LFS, 1 Hz) or high-frequency stimulation (HFS, 100 Hz) in the MD on amygdaloid kindling seizures. During the kindling acquisition, DBS in the MD was daily administered immediately after the kindling stimulus or before the kindling stimulus (preempt...
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PMID: 20600600
PDF is available here.
PDF is available here.
Biological Psychiatry (68)4 2010
Abstract
Movement Disorders (25)11 2010
Abstract
Movement Disorders (25)11 2010
Risk factors for executive dysfunction after subthalamic nucleus stimulation in Parkinson's disease.
Abstract
We analyzed data from the neuropsychological protocol in a randomized controlled study comparing DBS with best medical treatment (BMT). Change scores were calculated for the cognitive domains "global cognitive functioning," "memory," "working memory," "attention," and "executive function." These dom...
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PMID: 20589868
PDF is available here.
PDF is available here.
Abstract
We report efficacy data on ALIC-NA DBS in a patient with severe OCD and mild TS.
A 33-year-old man underwent bilateral ALIC-NA DBS. One month following implantation, a post-operative CT scan was obtained to verify lead locations. Yale Global Tic Severity Scales (YGTSS) and modified Rush Videotape Ra...
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PMID: 20178034
PDF is available here.
PDF is available here.
Revista de Neurologia (51)1 2010
Abstract
In the advanced stages of Parkinson's disease (PD), the conventional orally-administered pharmacological treatment can prove to be insufficient to control the motor complications associated with the disease. One of the causes involved in the genesis of the motor fluctuations that are observed in PD...
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PMID: 20568067
PDF is available here.
PDF is available here.
Abstract
We analysed the spectral and spatial characteristics of 314 microelectrode trajectories from 128 patients undergoing subthalamic nucleus deep brain stimulation surgery for Parkinson's disease. We correlated the subthalamic nucleus pathophysiology with the outcome of surgery, as evaluated by the thir...
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PMID: 20534648
PDF is available here.
PDF is available here.
Archives of Neurology (67)6 2010
Abstract
Abstract
Neurobiology of Disease (38)3 2010
Abstract
We need to keep an open mind as we move forward and especially that rational therapy may need to be patient and symptom specific. This review will summarize each disorder (depression, OCD and TS), review pathophysiology (both known and speculated), and update the current observations on DBS in each...
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PMID: 20096357
PDF is available here.
PDF is available here.
Neurobiology of Disease (38)3 2010
Abstract
We review the indications, techniques, and outcomes of DBS for cluster headache....
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PMID: 19501166
PDF is available here.
PDF is available here.
Abstract
Abstract
We briefly describe the evolution of surgical treatments for PD, and the rationale for current DBS procedures. We also provide details of our practice, including patient selection, surgical technique and postoperative stimulation programming and medication adjustment. Current and possible future alt...
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PMID: 20518607
PDF is available here.
PDF is available here.
Georgian medical news ()183 2010
Abstract
The mechanisms underlying pathogenesis of epileptic rections have been studied insufficiently as yet. Therefore, it is considered that determining the structures, transmitters, and receptors of the brain, which putatively produce development and intensity modulation of the convulsions, is highly impo...
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PMID: 20622273
PDF is available here.
PDF is available here.
Neurosurgery (66)5 2010
Abstract
We report a case of parkinsonism-hyperpyrexia syndrome (PHS), a rare complication resulting from discontinuation of antiparkinsonian medication, after a deep brain stimulation (DBS) procedure for bilateral subthalamic-nucleus (STN). CLINICAL PRESENTATION: A 66-year-old woman with an 11-year history...
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PMID: 20404676
PDF is available here.
PDF is available here.
Archives de Pédiatrie (17)5 2010
Abstract
Dystonia is not uncommon in childhood, but is clinically very heterogeneous. Therefore, introduction and follow-up of the treatment of dystonia in children are often a challenge for the physicians. Progresses in functional neurosurgery have open new fields in the treatment of dystonia in children, b...
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PMID: 20362421
PDF is available here.
PDF is available here.
Abstract
Comparison of the DBS-ON and DBS-OFF states revealed that neither amplitudes nor areas of the ERP components changed significantly; however, significant changes were observed in the latency of N100 potential when the target stimulus was applied, although there was no significant change in the latenc...
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PMID: 20116324
PDF is available here.
PDF is available here.
Abstract
Our findings suggest that the presence of pRBD in PD patients undergoing STN-DBS may be associated with a less favourable outcome and a more prominent development of axial symptoms over time.
Copyright 2010 Elsevier Ltd. All rights reserved....
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PMID: 20153238
PDF is available here.
PDF is available here.
Abstract
CNS Spectrums (15)5 2010
Abstract
Minnesota medicine (93)5 2010
Abstract
Abstract
Deep brain stimulation (DBS) is currently being tested as a possible treatment for treatment-refractory psychiatric disorders. Besides the hope set on this new therapeutic approach of DBS, there are at the same time doubts concerning the ethical acceptability in the treatment of individuals sufferin...
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PMID: 20422491
PDF is available here.
PDF is available here.
Abstract
Abstract
We tested the hypothesis that high-frequency electrical stimulation results in local thalamic glutamate release. Enzyme-linked glutamate amperometric biosensors were implanted in anesthetized rat thalamus adjacent to the stimulating electrode. Electrical stimulation was delivered to investigate the...
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PMID: 20332553
PDF is available here.
PDF is available here.
Abstract
These results, although based on a small sample, suggest that STN DBS, in addition to the effect to the mobility, might also favorably regulate sweat in idiopathic PD....
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PMID: 20022689
PDF is available here.
PDF is available here.
Abstract
Deep Brain Stimulation (DBS) has been successfully used throughout the world for the treatment of Parkinson's disease symptoms. To control abnormal spontaneous electrical activity in target brain areas DBS utilizes a continuous stimulation signal. This continuous power draw means that its implanted...
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PMID: 20411594
PDF is available here.
PDF is available here.
Abstract
Journal of Neurosurgery (112)4 2010
Abstract
The authors present the case of a 26-year-old man with a 10-15-year history of worsening bilateral dystonia and baseline chorea occurring up to 20 times per day that was exacerbated by stress and anxiety and was refractory to medical management. Paroxysmal nonkinesigenic dyskinesia was diagnosed, wh...
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PMID: 19799495
PDF is available here.
PDF is available here.
Abstract
The use of deep brain stimulation to control several motor diseases has renewed the interest of this technique for epilepsy. Several neurology and neurosurgery groups have applied this therapy to drug-resistant forms of epilepsy for which resective surgery cannot be applied. The choice of the subcor...
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PMID: 20125010
PDF is available here.
PDF is available here.
Biological Psychiatry (67)6 2010
Abstract
The present study suggests a negative effect of the IL1B gene on pharmacological response and amygdala and ACC function involving the same genotypes of two SNPs (rs16944, rs116343), which taken together increase the risk of nonremission over 6 weeks of antidepressant treatment in MDD.
Copyright 201...
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PMID: 20044070
PDF is available here.
PDF is available here.
Abstract
Our data should not be extrapolated to encourage MRI scanning beyond the present labeling. Rather, our data may contribute to further defining safe MRI scanning parameters that might ultimately be adopted in future product labeling as more centers report in detail their experiences....
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PMID: 20374084
PDF is available here.
PDF is available here.
Neurosurgery (66)3 Suppl Operative 2010
Abstract
The accuracy of identifying the correct brain location was 98.5%. Sensitivity of detecting passes intersecting the STN was 100%, and specificity was 84.9%. Anatomical location of the MER passes was calculated with a mean error of 0.06 mm (95% confidence interval, -0.54 to 0.42 mm) in the medial-late...
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PMID: 20173561
PDF is available here.
PDF is available here.
Journal of Neurosurgery (112)3 2010
Abstract
The authors' technical approach to placement of DBS electrodes adapts the procedure to a standard configuration 1.5-T diagnostic MR imaging scanner in a radiology suite. This method simplifies DBS implantation by eliminating the use of the traditional stereotactic frame and the subsequent requiremen...
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PMID: 19681683
PDF is available here.
PDF is available here.
Fortschritte der Neurologie - Psychiatrie (78 Suppl 1) 2010
Abstract
Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is a powerful treatment for advanced Parkinson's disease with levodopa-induced motor complications. Randomized controlled studies have shown that motor fluctuations and quality of life are significantly more improved by STN-DBS than by be...
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PMID: 20195941
PDF is available here.
PDF is available here.
Fortschritte der Neurologie - Psychiatrie (78 Suppl 1) 2010
Abstract
For the treatment of Parkinson's disease invasive therapies have a long tradition. Deep brain stimulation is a well-established treatment option for the treatment of advanced Parkinson's disease with fluctuations. Further promising interventions for invasive therapy of Parkinson's disease are transp...
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PMID: 20195935
PDF is available here.
PDF is available here.
Abstract
Revista de Neurologia (50 Suppl 2) 2010
Abstract
Patients who undergo DBS must be well-selected, weighing the risks and benefits, in order to obtain the best results with this treatment. Further multicentre studies are necessary to understand the role of DBS on NMS....
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PMID: 20205149
PDF is available here.
PDF is available here.
Biological Cybernetics (102)2 2010
Abstract
We constructed a computational model of the basal ganglia on the population level that generates LFPs to identify the critical pathophysiological alterations that lead to the expression of the beta band peak. To this end, we used experimental data reporting that the strengths of the synaptic connect...
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PMID: 20041261
PDF is available here.
PDF is available here.
Neurosurgery (66)2 2010
Abstract
The most common indication for bilateral invasive monitoring was bilateral ictal onsets on surface video-EEG (76.9%), followed by frequent interictal spikes contralateral to a single ictal focus (7.7%). Intracranial monitoring lasted an average of 8.2 days, with ictal events recorded in all cases. T...
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PMID: 20087126
PDF is available here.
PDF is available here.
Abstract
Treatment-resistant depression (TRD) presents major challenges for both patients and clinicians. There is no universally accepted definition of TRD, but results from the US National Institute of Mental Health's (NIMH) STAR*D (Sequenced Treatment Alternatives to Relieve Depression) programme indicate...
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PMID: 20088620
PDF is available here.
PDF is available here.
Abstract
Repetitive behavior has been increasingly reported in Parkinson's disease (PD) patients. This study evaluates the effect of Deep Brain Stimulation (DBS) treatment on existing repetitive behavior in three PD patients who underwent unilateral STN DBS surgery at the University of Florida Movement Disor...
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PMID: 20391184
PDF is available here.
PDF is available here.
Abstract
Abstract
Psychiatria polska (44)3 2010
Abstract
The deep brain stimulation DBS is the newest physical method of the treatment of depressive disorders. When applying of this technique in neurological illnesses (e.g., Parkinson's disease), mood changes were observed. In 2005, Helen Mayberg et al. used DBS in the therapy of the depression for the fi...
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PMID: 20672511
PDF is available here.
PDF is available here.
European Neurology (63)6 2010
Abstract
Experimental Neurology (221)1 2010
Abstract
We demonstrate for the first time that the beta band oscillations recorded in the local field potential of the subthalamic nuclei (STN), while appearing different across subjects, are occurring at the same frequencies bilaterally (p<0.001) and are coherent between the two STNs of individual PD subje...
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PMID: 19944098
PDF is available here.
PDF is available here.
European Neurology (63)3 2010
Abstract
We retrospectively analyzed 3 PD patients with suicide attempts after STN-DBS. All patients had normal pre- and immediate postoperative psychopathological and cognitive evaluations, with STN-DBS yielding a good motor benefit. Levodopa medication was markedly reduced. Albeit there was a significant r...
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PMID: 20197662
PDF is available here.
PDF is available here.
Abstract
There were twenty assessments (range, 3-5 per procedure) from nine countries--fourteen from Australia, Canada, and United Kingdom. The number of primary RCTs cited by the assessments ranged from 0 to 13. In the assessment reports, "headline" statements about the strength of evidence for efficacy (73...
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PMID: 20059787
PDF is available here.
PDF is available here.