Abstract
Our findings indicated that peripheral adaptations after ULLS could relate to the change in aerobic exercise capacity during one-legged exercise. Our results also suggest that intensive interval training prevents ULLS-induced deconditioning of both aerobic exercise capacity and skeletal muscle volum...
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PMID: 21197852
PDF is available here.
Abstract
Long-term immobilization is known to result in substantial bone loss. The present review examined the existing evidence for deterioration of bone structure during long-term disuse in humans. Paralysis due to spinal cord injury, long-term exposure to microgravity in space or tightly restricted mobili...
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PMID: 20637174
PDF is available here.
Abstract
The CMG demonstrated consistently higher scores on the BART (Days 20 to 40; Mean: CMG, 43.0 to 46.2 and CG, 30.2 to 25.5) and lower levels of arousal on the Affect Grid (Days 7 to 40; Mean: CMG, 6.9 to 6.7 and CG, 8.1 to 8.0) than did the CG. The CMG showed significantly higher performance on the Ar...
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PMID: 20681235
PDF is available here.
Abstract
Bone loss and renal stone are significant medical concerns for bed rest subjects and space flight astronauts. Bone mineral loss occurs as secondary osteoporosis due to the unloading of weight bearing bones during bed rest and space flight. Increased bone resorption and bone metabolic uncoupling prom...
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PMID: 20445282
PDF is available here.
Abstract
In both studies, serum calcium levels remained unchanged. Procollagen type I C-terminal propeptide was lower (P=0.03) in the bedrest phase than in the ambulatory phase in study A and tended to be lower (P=0.08) in bedrest in study B, whereas bone alkaline phosphatase was not affected in either study...
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PMID: 19765953
PDF is available here.
Abstract
The Frank-Starling mechanism describes the relationship between stroke volume and preload to the heart, or the volume of blood that is available to the heart--the central blood volume. Understanding the role of the central blood volume for cardiovascular control has been complicated by the fact that...
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PMID: 20052592
PDF is available here.
Abstract
Initial computed tomography scans of the patient revealed the presence of multiple pedicle fractures with spondylolysis. The patient was advised bed rest for the first 3 days, and when the acute pain subsided, she was permitted to ambulate with a lumbosacral corset. The patient was asymptomatic for...
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PMID: 20308947
PDF is available here.
Abstract
We report a case of a spontaneous occlusion of splenic pseudoaneurysm and renal pseudoaneurysm after blunt abdominal trauma. Angiography and embolization were not required, and contrast-enhanced multi-detector computed tomography was used to monitor the patient. This case shows that spontaneous occl...
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PMID: 18180131
PDF is available here.
Abstract
CIP is very frequent in Hungary probably due the extremely high number of previous induced abortion performed by dilatation and curettage method. CIP associates with an increased risk for preterm births; however, this increased risk was reduced by bed rest alone and mainly by therapeutic cerclage....
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PMID: 20586224
PDF is available here.
Abstract
Formal electrophysiological evaluation of patients with intensive care unit-acquired weakness can identify peripheral neuropathies, myopathies, and combinations of these disorders, although the correlation of these findings to weakness measurable at the bedside is not always precise. For routine cli...
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PMID: 20048676
PDF is available here.
Abstract
Lumbar disc herniation (LDH) is a common disorder among adults with degenerated lumbar intervertebral discs. However, its occurrence in childhood and adolescence is much less frequent mostly because children and adolescents tend to have a healthier lumbar spine as compared with adult...
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PMID: 19890666
PDF is available here.
Abstract
Prevention of preterm labor or arrest of ongoing premature labor in a twin gestation is more difficult to achieve than in singleton pregnancies. This clinical perspective is intended to review currently applied methods and to propose a more effective means to resolve this problem. A number of tocoly...
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PMID: 20506676
PDF is available here.
Abstract
We present a case of a successful pregnancy in a patient with preexisting uterine procidentia. CASE: A 44-year-old woman with a history of complete uterine prolapse presented with an unplanned pregnancy. Upon initial presentation at 15 weeks she had uterine prolapse with cervical elongation that pro...
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PMID: 20337211
PDF is available here.
Jörn Rittweger,
Gisela Beller,
Gabriele Armbrecht,
Edwin Mulder,
Björn Buehring,
Ulf Gast,
Fernando Dimeo,
Harald Schubert,
Arnold de Haan,
Dick F Stegeman,
Hans Schiessl and
Dieter Felsenberg
Abstract
We hypothesized that whole body vibration in combination with resistive exercise (RVE) would be an effective countermeasure. Twenty healthy male volunteers underwent horizontal bed rest for 56 days and were randomly assigned either to a group that performed RVE 11 times per week or to a group that u...
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PMID: 19732856
PDF is available here.
Abstract
There is currently not enough evidence to support a policy of routine hospitalisation for bed rest in multiple pregnancy. No reduction in the risk of preterm birth or perinatal death is evident, although there is a suggestion that fetal growth may be improved. For women with an uncomplicated twin pr...
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PMID: 20614420
PDF is available here.
Abstract
Despite a trend toward a reduction in bedrest time after left heart catheterization (LHC) in many Canadian centres, an evidence-based standard of practice has not been established. Canadian bedrest times range from two to four hours post-LHC. Two recent prospective non-randomized studies (n = 1,000)...
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PMID: 21141230
PDF is available here.
Abstract
The abnormal physiology that manifests itself in healthy humans during their adaptation to the microgravity of space has all the features of accelerated aging. The mechano-skeletal and vestibulo-neuromuscular stimuli which are below threshold in space, result in an overall greater than 10-fold more...
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PMID: 19851058
PDF is available here.
Abstract
To examine the influence of chronic time-in-bed (TIB) restriction on selected health-related outcome variables in older long sleepers.
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PMID: 19928386
PDF is available here.
Abstract
Spontaneous Intracranial Hypotension (SIH) is an uncommon headache syndrome. Patients classically present with orthostatic headache, tinnitus, and diplopia. The authors reported a 43 year-old man who presented with orthostatic headache, tinnitus, and hearing impairment for 3 months. Physical examina...
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PMID: 19938748
PDF is available here.
Abstract
Biopsy samples were taken from the vastus lateralis muscle of seven male subjects pre- and post-35 days bed rest (BR). The myosin heavy chain (MHC) isoform distribution of the samples was determined by densitometry of MHC bands separated by sodium dodecyl sulfate polyacrylamide gel e...
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PMID: 19883388
PDF is available here.
André Volschan,
Denilson Albuquerque,
Bernardo Rangel Tura,
Marcos Knibel,
José Péricles Esteves,
Luiz Carlos Bodanese,
Francisco Silveira,
João Pantoja,
Paulo Cesar Pereira da Silva e Souza,
João Mansur,
Evandro Tinoco Mesquita and
EMEP (Estudo Multicêntrico de Embolia Pulmonar) investigators
Abstract
Overall mortality was 14.1%. The following parameters were identified as independent death risk variables: age > 65 years, bed rest > 72h, chronic cor pulmonale, sinus tachycardia, and tachypnea. After risk stratification, mortalities of 5.4%, 17.8%, and 31.3% were found in the low, moderate and hig...
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PMID: 19838490
PDF is available here.
Abstract
This study focuses on the mid-term (four years) and long-term (ten years) functional outcome of patients treated nonoperatively for a type A spinal fracture without primary neurological deficit. Functional outcome was measured using the visual analogue scale spine score (VAS) and the Roland-Morris d...
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PMID: 18548248
PDF is available here.
Abstract
Loss of functional weightbearing during spaceflight or extended bed rest (BR) causes swelling of the lumbar intervertebral discs (IVDs), elongates the spine, and increases the incidence of low back pain (LBP). Effective interventions for the negative effects of unloading are critical...
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PMID: 19356986
PDF is available here.
Abstract
We found significant differences in the mean loss of wedge and kyphosis angle correction between patients immediately ambulated and those who had 4 weeks of bedrest (0.71 masculine v. - 4.73 masculine for wedge and 1.81 masculine v. - 6.55 masculine for kyphosis, respectively). There was significant...
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PMID: 19503666
PDF is available here.
Abstract
We hypothesized that an exercise prescription, combining supine aerobic treadmill exercise in a lower body negative pressure (LBNP) chamber followed by 10 min of resting LBNP, three to four times a week, and flywheel resistive training every third day would maintain orthostatic tolerance (OT) in wom...
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PMID: 19247686
PDF is available here.
William D Schweickert,
Mark C Pohlman,
Anne S Pohlman,
Celerina Nigos,
Amy J Pawlik,
Cheryl L Esbrook,
Linda Spears,
Megan Miller,
Mietka Franczyk,
Deanna Deprizio,
Gregory A Schmidt,
Amy Bowman,
Rhonda Barr,
Kathryn E McCallister,
Jesse B Hall and
John P Kress
Abstract
We assessed the efficacy of combining daily interruption of sedation with physical and occupational therapy on functional outcomes in patients receiving mechanical ventilation in intensive care.
Sedated adults (>/=18 years of age) in the ICU who had been on mechanical ventilation for...
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PMID: 19446324
PDF is available here.
Abstract
We determined the impact of 60-day bedrest (BR, n=8), 60-day bedrest with exercise-training (BRE, n=8), and 60-day bedrest with a leucine-enriched, high-protein diet (BRN, n=8) on muscle protein composition. Vastus lateralis and soleus muscle biopsies were analyzed for global protein fractions (mixe...
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PMID: 19229964
PDF is available here.
Abstract
There was no difference in baseline patient comorbidities and no significant difference in the number of grafts lost, the number of dressing clinics, bleeding, or wound infections. CONCLUSION: The results suggest that 2 days of convalescence after split-thickness skin grafting to the lower legs may...
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PMID: 19400884
PDF is available here.
Abstract
Mortality was higher among stroke patients with low GCS scores (p < 0.01). Leukocyte counts and systolic blood pressures were significantly higher among non-surviving patients (p = 0.04). No association was found between QT parameters and mortality (all p > 0.05). Among survivors, post-hospitalizati...
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PMID: 19299219
PDF is available here.
Abstract
HDBR transiently reduced muscle sympathetic nerve activity, RR, heart rate variability and baroreceptor reflex sensitivity late during HDBR or early during the recovery phase. Conversely, oscillatory profiles of RR and systolic arterial pressure variability were maintained throughout. Responsiveness...
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PMID: 19262409
PDF is available here.
Abstract
There are controversies surrounding the indications, time and place for elective surgery, and role of multistage operations in the treatment of complicated diverticular disease. Most patients with uncomplicated diverticulitis can be managed non-operatively. Previous indications for elective surgery...
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PMID: 19120008
PDF is available here.
Abstract
In this paper, the effects of bed rest-induced cardiovascular deconditioning were investigated by means of a previously developed multivariate model for the assessment of arterial control of circulation. The vascular response to exercise and tilt, before and after a 14-day head down...
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PMID: 19963898
PDF is available here.
Abstract
This article is the second in a three-part series discussing the effects of long periods of bedrest on the body. It explores what happens to the gastrointestinal, endocrine and renal systems when a person is confined to bed. The effects on the reproductive and nervous systems are also covered. Part...
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PMID: 19579399
PDF is available here.
Abstract
This is the first in a three-part series on the physiological effects of bedrest. It discusses what happens to the cardiovascular, respiratory and haematological systems when a person is bedridden. Other articles in the series will cover the effects of immobility on the digestive, endocrine, renal,...
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PMID: 19548502
PDF is available here.
Abstract
The ECR for intervertebral discs was significantly lower after bed rest than before bed rest (P < 0.01). The ECR for paravertebral equivalent cross-relaxation rate muscles was significantly higher after bed rest than before bed rest (P < 0.05). CONCLUSION: We obtained results indicating that after b...
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PMID: 19214687
PDF is available here.
Abstract
An 8-year-old girl presented at the Accident & Emergency Department with torticollis and neck pain after falling on her head from a climbing frame. A computed tomography scan revealed a Gehweiler type 1 avulsion fracture combined with widening of an anatomically variant single anterior synchondrosis...
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PMID: 19785780
PDF is available here.
Abstract
Eight volunteered male test-subjects (20-40 y.o.) took part in an experiment with 21-hr bed rest aimed to investigate trends in the hemostasis parameters (activated partial thromboplastin time, prothrombin time, thrombin time, fibrinogen, plasminogen, D-dimers, soluble fibrin-monomer complexes (SFMC...
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PMID: 20169734
PDF is available here.
Abstract
Effects of 120-d bed rest on chromosomal aberration rate were studied in lymphocytes of human peripheral blood in vivo. Chromosomal analysis revealed statistically significant increases in dicentrics and paired acentric fragments in blood lymphocytes of human test-subjects.
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PMID: 20169743
PDF is available here.
Abstract
Net muscle force recorded during voluntary contractions with multiple agonist muscles is the summated result of individual muscle forces. The purpose of this article is to synthesize recent findings from several studies on the modulations of muscle activity and force fluctuations during steady volun...
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PMID: 19092689
PDF is available here.
Abstract
Resolution of subjective pain was faster during the first three days and near absent at the end of the study period in group A (p < 0.001). Objective pain seriously reduced in group A during the observation period while in group B decreased during the first three days almost by half but remained con...
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PMID: 20191834
PDF is available here.
Abstract
This study demonstrates that the transfer content is not affected by the immediate ambulation after transfer, illustrating why there is no rationale for bedrest after transfer.
Copyright 2009 S. Karger AG, Basel....
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PMID: 19590224
PDF is available here.
Abstract
A thorough review of current and classic literature was completed to distinguish the influence of bedrest or ambulation on patient treatment outcomes with confirmed deep vein thrombosis.
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PMID: 19927966
PDF is available here.
Abstract
Control of stress and anxiety and the promotion of comfort are challenges facing health practitioners involved in catheterization. The aim of this case-control study was to examine the effect of music on the levels of anxiety, stress, and depression experienced by patients undergoing coronary angiog...
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PMID: 19731780
PDF is available here.
Abstract
Patients with high-grade liver injuries have a longer recovery, more complications, and greater use of resources than in patients with similar injuries to the spleen....
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PMID: 19040949
PDF is available here.
Abstract
Nurses' responses reflected substantial gaps in their knowledge and theoretical understanding of deconditioning, and a strong belief in the need for more education on the prevention of it. Levels of confidence in preventing deconditioning in older adults were modest, but participants expressed posit...
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PMID: 19110729
PDF is available here.
Abstract
NOM of blunt splenic injuries had a 96% success rate following our protocol. The guideline successfully identified all the patients failing NOM during the inpatient observation period with the exception of one patient that was noncompliant to protocol. This guideline for observation is safe and effe...
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PMID: 19077626
PDF is available here.
Abstract
In acute DVT , early walking, thrombus location, and duration of the symptoms did not influence the incidence of symptomatic PE....
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PMID: 19078912
PDF is available here.
Abstract
Adrenaline and noradrenaline concentrations increased significantly in both groups, while the concentration of C-reactive protein decreased. The concentration of C-reactive protein was significantly higher (CTL: 0.028 +/- 0.005 mg x dl(-1); CMS: 0.025 +/-0.003 mg x dl(-1)), and that of adrenaline wa...
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PMID: 19070303
PDF is available here.