Abstract
Lennox-Gastaut syndrome (LGS) is an intractable childhood-onset epileptic encephalopathy. Seizure freedom is rare in LGS. One of the hallmarks of LGS is medical intractability, with generally poor response to antiepileptic drugs (AEDs). Nevertheless, several treatment options are available that can m...
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PMID: 21790561
PDF is available here.
Abstract
We hypothesised that tonic epidural spinal cord stimulation can modulate spinal circuitry in human beings into a physiological state that enables sensory input from standing and stepping movements to serve as a source of neural control to undertake these tasks.
A 23-year-old man who...
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PMID: 21601270
PDF is available here.
Henry G HG Chambers,
Kevin G KG Shea,
Allen F AF Anderson,
Tommy J Jojo TJ Brunelle,
James L JL Carey,
Theodore J TJ Ganley,
Mark V MV Paterno,
Jennifer M JM Weiss,
James O JO Sanders,
William C WC Watters,
Michael J MJ Goldberg,
Michael W MW Keith,
Charles M CM Turkelson,
Janet L JL Wies,
Laura L Raymond,
Kevin M KM Boyer,
Kristin K Hitchcock,
Sara S Anderson,
Patrick P Sluka,
Catherine C Boone and
Nilay N Patel
Abstract
This clinical practice guideline is based on a series of systematic reviews of published studies in the available literature on the diagnosis and treatment of osteochondritis dissecans of the knee. None of the 16 recommendations made by the work group is graded as strong; most are graded inconclusive...
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PMID: 21536629
PDF is available here.
Abstract
Sacral neuromodulation is a well researched and successful treatment for functional bowel disorders. Indications have expanded throughout the years and various studies have been published on clinical efficacy or on technique improvement. The main goal of this retrospective study was to systematicall...
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PMID: 21160319
PDF is available here.
Abstract
We examined the effect of bipolar electrical-conditioning stimulation (50 Hz, 0.2 ms, 5 min) of the dorsal column and lumbar dorsal roots on the response properties of spinal wide dynamic range (WDR) neurons in rats after L5 spinal nerve injury. The conditioning stimulation intensity was set at the...
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PMID: 21068658
PDF is available here.
Abstract
I were 1/96/23, 0/17/103, 0/0/ 120 at the 3rd day, the 7th day and the 14th day after treatment respectively, while in the control group they were 4/42/0, 2/ 44/0, 0/4/42 respectively. There were statistical differences between the two groups with Kruskal-Wallis test. The percent of mid and severe g...
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PMID: 21265202
PDF is available here.
Abstract
Our data show SNM to be an efficient investment with an acceptable incremental cost-effectiveness ratio and a limited impact on the total allocated budget for fecal incontinence....
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PMID: 21178862
PDF is available here.
Abstract
Epilepsy is a common neurological disorder, and between one fourth and one third of the patients do not obtain seizure freedom after treatment with antiepileptic drugs. If the epileptic seizures in such patients have severe consequences, the patients should be assessed for epilepsy surgery. In case...
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PMID: 21055380
PDF is available here.
Abstract
This paper is a summary of the biofeedback technology for the reflex electrical stimulation device to assist walking. The experiments showed that electrical stimulation resulted in prominent stimulation with less habituation. The research elements were an input-type brain machine interface (BMI), fu...
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PMID: 21068460
PDF is available here.
Abstract
Among the 87 patients, 36 had surgical revision of the device for the following reasons: device-related failure due to infection in 4 (successful reimplant in 4), electrode displacement in 2, electrode breakage in 2 (reimplantation of electrode in 4), and dysfunction owing to impedance increase of t...
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PMID: 20940598
PDF is available here.
Abstract
More prevalent in women than men, clinical depression affects approximately 15 million American adults in a given year. Psychopharmaceutical therapy accompanied by psychotherapy and wellness interventions (e.g., nutrition, exercise, counseling) is effective in 80% of diagnosed cases. A lesser known...
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PMID: 20669869
PDF is available here.
Abstract
Neurogenic bladder resulting from spinal cord injury and spina bifida has a profound impact on voiding function. This article reviews the current literature with regards to electrical stimulation for neurogenic bladder and the clinical outcomes associated with sacral neuromodulation, pudendal neurom...
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PMID: 20955907
PDF is available here.
Abstract
Our results suggest a potentially beneficial effect of noninvasive cortical stimulation during rehabilitative motor training of patients who have suffered from subacute strokes....
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PMID: 20962598
PDF is available here.
Abstract
Primary care clinicians need to move beyond first-line therapy for major depression. While initial treatment is ineffective in about two-thirds of patients, patients who have not responded to such initial treatments can be managed effectively. The severity of depression is as high in primary care as...
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PMID: 20977873
PDF is available here.
Abstract
Sciatic pain is often misleading and establishing the link with a local muscular cause can be difficult and lead to errors, especially when faced with a young sportsman, with typical discogenic pain. Simple, specific and reproducible tests enable a better identification and treatment of a muscular c...
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PMID: 21033479
PDF is available here.
Abstract
Of all the joints in the human body, the shoulder has the greatest range of motion. This allows complex movements and functions to be carried out, and is of vital importance to the activities of daily living and work. Any restriction or pain that involves the joint puts a huge amount of strain on pa...
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PMID: 20938608
PDF is available here.
Abstract
The Ponseti method for clubfoot treatment offers satisfactory initial correction, but success correlates with abduction brace compliance, which is variable. Electrical stimulation as a dynamic intervention to prevent relapses was investigated. Data were compared to a control group. There was a signi...
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PMID: 20581693
PDF is available here.
Abstract
We reported that 20 Hz ES increased the number of regenerated and myelinated axons at 4 and 8 weeks after injury. P0 level in the ES-treated groups, as well as myelin sheath thickness, were enhanced compared with the controls. The earlier peak Par-3 in the ES-treated groups indicated earlier initiat...
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PMID: 20553821
PDF is available here.
Abstract
Our findings suggest that a combinatorial treatment strategy of using brief ES and TP together promises to be an effective therapeutic intervention for promoting regeneration following facial nerve injury. Administration of P neither augments nor hinders recovery....
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PMID: 20641084
PDF is available here.
Abstract
In a pediatric population sacral neuromodulation is effective for bladder and bowel dysfunction and should be considered before irreversible surgery.
Copyright (c) 2010 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved....
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PMID: 20561645
PDF is available here.
Abstract
This study reports on the preliminary results of external neuromyogenic electrostimulation (ENS) for the treatment of anorectal continence problems.
A total of seventeen patients with anorectal malformations (n=11), Hirschsprung's disease (n=5) or pelvi-perineal trauma (n=1) were included in the stu...
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PMID: 20503145
PDF is available here.
Abstract
Depressive disorders are highly prevalent and are a leading cause of disability, morbidity, and mortality worldwide; however, they often remain undertreated or untreated. This article provides a broad overview of the many strategies for treating depression. More than 24 antidepressant medications an...
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PMID: 20675972
PDF is available here.
Abstract
The use of electrotherapy has been part of physical therapy treatment for the past few decades. There have been numerous modalities used such as TENS, interferential, diathermy, magnetic therapy, ultrasound, laser and surface electromyography to name a few. There has been an upsurge in the past deca...
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PMID: 20590871
PDF is available here.
Abstract
Eight randomized controlled trials were included. The average Physiotherapy Evidence Database Scale score was 4 out of possible maximum 10. The effect sizes for quadriceps strength measures (isometric or isokinetic torque) from 7 studies ranged from -0.74 to 3.81 at approximately 6 weeks postoperati...
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PMID: 20592480
PDF is available here.
Abstract
Occipital nerve stimulation may be considered a safe and effective therapeutic option in the drug-resistant cluster headache. However, studies with more patients and a longer follow-up are required to evaluate the efficacy of the technique....
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PMID: 20568064
PDF is available here.
Abstract
ICD shocks are common after implantation of LVADs, with nearly equal numbers of appropriate and inappropriate shocks. ICD shocks are associated with higher mortality. Larger studies are needed for assessing the independent relationship of ICDs to a variety of clinical outcomes in patients with LVADs...
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PMID: 20347337
PDF is available here.
Abstract
The combination of amplitude-modulated medium-frequency electrostimulation with EMG-biofeedback in the triple target regimen is superior to EMG-biofeedback alone in the treatment of anal incontinence. Therapy programs for fecal incontinence are most effective if patients participate for longer than...
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PMID: 20551752
PDF is available here.
Abstract
Nearly 60% of patients who received sacral nerve stimulation for constipation experienced at least one reportable event. Although the events were often resolved by reprogramming, more than one-third required surgical intervention or discontinuation of therapy. Patients undergoing sacral nerve stimul...
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PMID: 20551750
PDF is available here.
Abstract
We report our experience with four patients with spinal cord injury in a pilot project, presenting for laparoscopic insertion of diaphragmatic phrenic nerve pacing leads inserted. The surgery took about two hours and diaphragmatic mapping precluded muscle relaxants. We used desflurane with remifenta...
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PMID: 20715740
PDF is available here.
Kenneth A Follett,
Frances M Weaver,
Matthew Stern,
Kwan Hur,
Crystal L Harris,
Ping Luo,
William J Marks,
Johannes Rothlind,
Oren Sagher,
Claudia Moy,
Rajesh Pahwa,
Kim Burchiel,
Penelope Hogarth,
Eugene C Lai,
John E Duda,
Kathryn Holloway,
Ali Samii,
Stacy Horn,
Jeff M Bronstein,
Gatana Stoner,
Philip A Starr,
Richard Simpson,
Gordon Baltuch,
Antonio De Salles,
Grant D Huang,
Domenic J Reda and
CSP 468 Study Group
Abstract
Patients with Parkinson's disease had similar improvement in motor function after either pallidal or subthalamic stimulation. Nonmotor factors may reasonably be included in the selection of surgical target for deep-brain stimulation. (ClinicalTrials.gov numbers, NCT00056563 and NCT01076452.)
2010 Ma...
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PMID: 20519680
PDF is available here.
Abstract
Only stimulated long-term patients (+4.9%) showed a significant (p = 0.013) increase in muscle layer thickness compared with sham-stimulated patients (-3.2%). CONCLUSION: Neuromuscular electrical stimulation appears to be a useful adjunct to revert muscle wasting in intensive care unit long-term pat...
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PMID: 20549166
PDF is available here.
Abstract
After experiencing excellent pain relief over the next 2 days, the patients were implanted with permanent leads and rechargeable or non-rechargeable generator 2-4 weeks later. They reported sustained pain relief at 12-month follow-up visits. CONCLUSION: PNFS provides an effective alternative treatme...
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PMID: 20672555
PDF is available here.
Abstract
N-Acetyl-aspartate (NAA) levels of the stimulated and control rats were the same 16 +/- 2 h post-MCAO (0.52 +/- 0.03, 0.54 +/- 0.03). At 28 days post-occlusion, NAA levels were significantly higher in the treated group (0.60 +/- 0.04) compared with those of the untreated animals (0.50 +/- 0.04; P <...
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PMID: 20512887
PDF is available here.
Abstract
Transcranial stimulation with weak direct current (DC) has been valuable in exploring the effect of cortical modulation on various neural networks. Less attention has been given, however, to cranial stimulation with low-intensity alternating current (AC). Reviewing and discussing the...
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PMID: 20040569
PDF is available here.
Abstract
Transcranial stimulation with weak direct current (DC) has been valuable in exploring the effect of cortical modulation on various neural networks. Less attention has been given, however, to cranial stimulation with low-intensity alternating current (AC). Reviewing and discussing the...
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PMID: 20040569
PDF is available here.
Abstract
Coverage with evidence development studies may yield important information not apparent from randomized clinical trials concerning long-term risks and benefits of a therapy in clinical practice for specific subpopulations, but are likely to be met with criticism from interested parties....
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PMID: 20473203
PDF is available here.
Abstract
I and type II, based on precipitating events. This syndrome manifests in 3 progressive stages, displaying peripheral and central neurologic aberrancies. The exact triggering mechanism is unclear but appears to involve neurogenic inflammation from axonal damage to small-fiber distal nerves. Central s...
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PMID: 20572407
PDF is available here.
Abstract
We report two cases of chronic stroke in which the magnitude of infarct was too large to be improved with single perirolandic stimulation. Patient 1 had severe hemiplegia associated with large cortical infarct in the right frontoparietal area. The patient could neither stand independently or walk. P...
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PMID: 19426588
PDF is available here.
Abstract
After total knee arthroplasty, most elderly subjects can tolerate neuromuscular electrical stimulation at current intensities sufficient to elicit quadriceps femoris muscle contractions within the therapeutic range recommended for muscle strengthening. Although male subjects can tolerate stronger cu...
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PMID: 20489392
PDF is available here.
Abstract
We describe uncommon side effects owing to spinal cord stimulation in a patient with chronic neuropathic pain. Our patient developed unexpected urinary retention during electrical epidural stimulation. RESULTS AND DISCUSSION: This case report highlights the incomplete knowledge about the mechanism o...
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PMID: 20473052
PDF is available here.
Abstract
Two patients experienced clinically meaningful (>or=30%) pain reduction throughout the entire 5-day treatment period. Apparent carryover effect in pain reduction also was observed after daily stimulation. After explant, pain returned to baseline, increasing 36.8% to 45.6% relative to average reduced...
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PMID: 20473041
PDF is available here.
Abstract
We gathered data from questionnaires before implantation, at 1 month after implantation, and at long-term follow-up. Twenty-six patients consented and were phenotyped. At 1 month follow-up and at long-term follow-up a significant decrease in all pain parameters was noted, as well as in analgesic use...
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PMID: 20511204
PDF is available here.
Abstract
We will analyze the device in detail, its placement and the results of studies evaluating its efficacy....
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PMID: 20420555
PDF is available here.
Abstract
We present the technique of pudendal nerve neuromodulation with neurophysiology guidance as a treatment option for RCPPP. This technique is a two-step procedure that includes electrode implantation under neurophysiology guidance followed by the implantation of a permanent generator after a successfu...
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PMID: 20012596
PDF is available here.
Abstract
The pathogenesis of hypertension and its mode of progression are complex, multifactoral and incompletely understood. However, there is accumulating evidence from humans and animal models of hypertension indicating that excessive central sympathetic nerve activity (SNA) plays a pathogenic role in tri...
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PMID: 20304932
PDF is available here.
Abstract
We review briefly here vagus nerve stimulation, the various brain stimulations procedures, multiples subpial transsections, and the corpus callosotomy. For each procedure, we will discuss its indication and outcome....
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PMID: 20499579
PDF is available here.
Abstract
Despite increasing knowledge of cellular and molecular mechanisms determining the success or failure of peripheral nerve regeneration, no effective treatments for peripheral nerve injury exist. Newly developed and validated approaches for precise numerical assessment of motor deficits have recently...
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PMID: 20454881
PDF is available here.
Abstract
Our study supports the involvement of the prefrontal cortex in the pathophysiology of tinnitus....
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PMID: 20186404
PDF is available here.
Abstract
We observed that US treatment and ES treatment were effective in improving pain, isometric extensor muscle strength, and QOL in patients with CLBP....
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PMID: 19644691
PDF is available here.
Abstract
The conduction of pathogenetically substantiated treatment--enterosorption together with procedures of electrostimulation--in patients, suffering obturation jaundice of nontumoral genesis, secures favorable course of postoperative period, the hepatorenal insufficiency prophylaxis, and postcholecyste...
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PMID: 20623975
PDF is available here.
Abstract
Pain scores were measured using a visual analog scale and the McGill Short Form preoperatively and during tonic and burst stimulation. Paresthesia was scored as present or not present. Burst stimulation was significantly better for pain suppression, by both the visual analog scale score and the McGi...
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PMID: 20404705
PDF is available here.